Page last updated: 2024-10-25

ciprofloxacin and Leg Ulcer

ciprofloxacin has been researched along with Leg Ulcer in 12 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research Excerpts

ExcerptRelevanceReference
"Forty-eight patients with peripheral vascular disease (46 with diabetes mellitus) who presented to the hospital for treatment of lower extremity infections were randomized in a blinded fashion to receive oral ciprofloxacin at a dosage of either 750 mg or 1,000 mg twice daily."9.06Therapy of lower extremity infections with ciprofloxacin in patients with diabetes mellitus, peripheral vascular disease, or both. ( Canter, K; Clabots, C; Fasching, CE; Gerding, DN; Lissack, LM; Peterson, LR, 1989)
"Ciprofloxacin was clinically more effective than the standard therapy in reducing the size of the ulcer (p less than 0."6.66A comparative study of ciprofloxacin and conventional therapy in the treatment of patients with chronic lower leg ulcers infected with Pseudomonas aeruginosa or other gram-negative rods. ( Kariniemi, AL; Karppinen, L; Valtonen, V, 1989)
"Forty-eight patients with peripheral vascular disease (46 with diabetes mellitus) who presented to the hospital for treatment of lower extremity infections were randomized in a blinded fashion to receive oral ciprofloxacin at a dosage of either 750 mg or 1,000 mg twice daily."5.06Therapy of lower extremity infections with ciprofloxacin in patients with diabetes mellitus, peripheral vascular disease, or both. ( Canter, K; Clabots, C; Fasching, CE; Gerding, DN; Lissack, LM; Peterson, LR, 1989)
"The aims of this study were to evaluate factors influencing the distribution of ciprofloxacin in tissue of patients suffering from varying degrees of peripheral arterial disease (PAD)."3.83Factors Affecting Penetration of Ciprofloxacin in Lower Extremity Ischemic Tissues. ( Azzopardi, LM; Camilleri, L; Cassar, K; LaFerla, G; Serracino-Inglott, A; Vella, J; Vella, M, 2016)
"Ciprofloxacin was clinically more effective than the standard therapy in reducing the size of the ulcer (p less than 0."2.66A comparative study of ciprofloxacin and conventional therapy in the treatment of patients with chronic lower leg ulcers infected with Pseudomonas aeruginosa or other gram-negative rods. ( Kariniemi, AL; Karppinen, L; Valtonen, V, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Salm, J1
Böhme, T1
Noory, E1
Beschorner, U1
Kramer, TS1
Westermann, D1
Zeller, T1
Dilhari, A1
Pathirage, S1
Gunasekara, C1
Fernando, N1
Weerasekara, D1
McBain, A1
Weerasekera, M1
Pires, BMFB1
de Oliveira, BGRB1
de Oliveira, FP1
de Almeida Silva, KCF1
Del Peloso, PF1
Ferreira-Carvalho, BT1
de Paula, GR1
Teixeira, LA1
Vella, J1
Vella, M1
Cassar, K1
Camilleri, L1
Serracino-Inglott, A1
Azzopardi, LM1
LaFerla, G1
Grocholski, AS1
Delage, M1
Samimi, M1
Maruani, A1
Rozin, AP1
Egozi, D1
Ramon, Y1
Toledano, K1
Braun-Moscovici, Y1
Markovits, D1
Schapira, D1
Bergman, R1
Melamed, Y1
Ullman, Y1
Balbir-Gurman, A1
Bousquet, A1
Demoures, T1
Malfuson, JV1
Martinaud, C1
Soler, C1
Livasy, CA1
Kaplan, AM1
Colsky, AS1
Kirsner, RS1
Kerdel, FA1
Semret, M1
Koromihis, G1
MacLean, JD1
Libman, M1
Ward, BJ1
Valtonen, V1
Karppinen, L1
Kariniemi, AL1
Peterson, LR1
Lissack, LM1
Canter, K1
Fasching, CE1
Clabots, C1
Gerding, DN1

Reviews

1 review available for ciprofloxacin and Leg Ulcer

ArticleYear
Ciprofloxacin-induced toxic epidermal necrolysis: a case report.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Fatal Outcome; Female; Humans; Leg Ulcer; Male; M

1997

Trials

2 trials available for ciprofloxacin and Leg Ulcer

ArticleYear
A comparative study of ciprofloxacin and conventional therapy in the treatment of patients with chronic lower leg ulcers infected with Pseudomonas aeruginosa or other gram-negative rods.
    Scandinavian journal of infectious diseases. Supplementum, 1989, Volume: 60

    Topics: Administration, Oral; Aged; Bacterial Infections; Chlorhexidine; Ciprofloxacin; Disinfectants; Drug

1989
Therapy of lower extremity infections with ciprofloxacin in patients with diabetes mellitus, peripheral vascular disease, or both.
    The American journal of medicine, 1989, Volume: 86, Issue:6 Pt 2

    Topics: Adult; Bacteria; Bacterial Infections; Ciprofloxacin; Clinical Trials as Topic; Diabetes Complicatio

1989

Other Studies

9 other studies available for ciprofloxacin and Leg Ulcer

ArticleYear
Arterial leg ulcers-Bacterial patterns, antimicrobial resistance and clinical characteristics, a retrospective single-centre cohort, 2012-2021.
    PloS one, 2023, Volume: 18, Issue:8

    Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Clindamycin; Drug Resistance, Bacterial; Escherichia

2023
    Journal of wound care, 2020, 01-02, Volume: 29, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Cefuroxime; Ciprofloxacin; Cloxacillin; D

2020
Ciprofloxacin-Resistant Kerstersia gyiorum Isolated From a Chronic Wound in Brazil: A Case Report.
    Wound management & prevention, 2020, Volume: 66, Issue:10

    Topics: Aged, 80 and over; Alcaligenaceae; Brazil; Ciprofloxacin; Disease Resistance; Female; Humans; Leg Ul

2020
Factors Affecting Penetration of Ciprofloxacin in Lower Extremity Ischemic Tissues.
    The international journal of lower extremity wounds, 2016, Volume: 15, Issue:2

    Topics: Aged; Amputation, Surgical; Anti-Bacterial Agents; Chromatography, Liquid; Ciprofloxacin; Debridemen

2016
[Acute dermohypodermitis of the right leg (S. putrefaciens) after sea bathing].
    Annales de dermatologie et de venereologie, 2009, Volume: 136, Issue:1

    Topics: Acute Disease; Aged; Anti-Infective Agents; Ciprofloxacin; Humans; Leg Ulcer; Male; Oceans and Seas;

2009
Large leg ulcers due to autoimmune diseases.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; Ciprofloxacin; Cyclophosphamide;

2011
Campylobacter jejuni cutaneous infection in a patient with graft versus host disease.
    Medecine et maladies infectieuses, 2012, Volume: 42, Issue:5

    Topics: Campylobacter Infections; Campylobacter jejuni; Ciprofloxacin; Erysipelas; Graft vs Host Disease; He

2012
Analysis of antibiotic susceptibilities of skin wound flora in hospitalized dermatology patients. The crisis of antibiotic resistance has come to the surface.
    Archives of dermatology, 1998, Volume: 134, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Dermatitis; Drug Resistance, Microbial;

1998
Mycobacterium ulcerans infection (Buruli ulcer): first reported case in a traveler.
    The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:5

    Topics: Adult; Africa; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxa

1999