Page last updated: 2024-10-25

ciprofloxacin and Kidney Failure

ciprofloxacin has been researched along with Kidney Failure in 20 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"The antibiotic nitrofurantoin is commonly used to treat uncomplicated urinary tract infections."7.81Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women. ( Gandhi, S; Garg, AX; Jain, AK; Liu, AR; McArthur, E; Moist, L; Singh, N; Sood, MM, 2015)
"The purpose of this study is to describe clinical characteristics of Salmonella bacteremia in adult patients and analyze ciprofloxacin-nonsusceptible isolates."7.81Clinical characteristics in adult patients with Salmonella bacteremia and analysis of ciprofloxacin-nonsusceptible isolates. ( Cheng, MW; Lee, CM; Lin, CC; Liu, CP; Shih, SC; Wang, NY; Weng, LC; Wu, AY, 2015)
" After intravenous dosing of ciprofloxacin (10-30 mg kg(-1)), ciprofloxacin levels in plasma and brain were measured in normal rats (Wistar, male, 10-week-old) and those with acute renal and hepatic injuries which were induced by uranyl nitrate and carbon tetrachloride (CCl4), respectively."5.30Distribution of ciprofloxacin into the central nervous system in rats with acute renal or hepatic failure. ( Hirano, H; Ichikawa, N; Iwamoto, K; Naora, K, 1999)
"Oral ciprofloxacin therapy was continued for 10 days and the patient remained free of symptoms with formed stools thereafter."5.29Pseudomonas aeruginosa as a cause of infectious diarrhea successfully treated with oral ciprofloxacin. ( Porco, FV; Visconte, EB, 1995)
"The antibiotic nitrofurantoin is commonly used to treat uncomplicated urinary tract infections."3.81Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women. ( Gandhi, S; Garg, AX; Jain, AK; Liu, AR; McArthur, E; Moist, L; Singh, N; Sood, MM, 2015)
"The purpose of this study is to describe clinical characteristics of Salmonella bacteremia in adult patients and analyze ciprofloxacin-nonsusceptible isolates."3.81Clinical characteristics in adult patients with Salmonella bacteremia and analysis of ciprofloxacin-nonsusceptible isolates. ( Cheng, MW; Lee, CM; Lin, CC; Liu, CP; Shih, SC; Wang, NY; Weng, LC; Wu, AY, 2015)
"This analysis demonstrates for the first time that, used in a stepwise fashion, ciprofloxacin and leflunomide are effective and safe treatments for BK viremia in PRTR."3.80A novel treatment regimen for BK viremia. ( Cheam, H; Ettenger, RB; Malekzadeh, MH; Tsai, EW; Zaman, RA, 2014)
" No dosage modifications were made in patients with renal impairment."2.68The pharmacokinetics of intravenous ciprofloxacin 400 mg 12 hourly in patients with severe sepsis: the effect of renal function and intra-abdominal disease. ( Hedges, AJ; Jones, EM; Lovering, AM; MacGowan, AP; McMullin, CM; Reeves, DS; White, LO, 1997)
"Malacoplakia is a rare chronic inflammatory disease that most commonly involves the genitourinary tract with a wide spectrum of clinical presentation."1.48Bilateral hydroureteronephrosis with renal failure caused by malacoplakia. ( Audino, P; Cavallone, B; Di Stasio, A; Serao, A; Tiranti, D; Vota, P, 2018)
"NC, with renal failure secondary to bilateral dysplastic kidneys, received an LRD renal transplant (tx) at 17 months of age."1.40Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child. ( Habib, S; Latiolais, LS; McClure, GB; Reisman, L; Vanchiere, JA, 2014)
" The relationship between the efficacies of these 3 dosage schemes could have been predicted by AUC above MIC and AUIC, but not by AUC/MIC or time above MIC."1.33Dose adjustment of ciprofloxacin in renal failure: reduce the dose or prolong the administration interval? ( Czock, D; Rasche, FM, 2005)
"To define in critically ill patients receiving intravenous (iv) ciprofloxacin (200 mg or 400 mg twice daily) and undergoing routine therapeutic drug monitoring (TDM) the interindividual pharmacokinetic variability and the reliable pharmacodynamic breakpoint enabled by these fixed dosing regimens according to the PK/PD principles and to the pattern of susceptibility to this antibiotic."1.33Which reliable pharmacodynamic breakpoint should be advised for ciprofloxacin monotherapy in the hospital setting? A TDM-based retrospective perspective. ( Furlanut, M; Pavan, F; Pea, F; Poz, D; Viale, P, 2006)
"Levofloxacin clearance was substantially increased during both CVVH and CVVHDF, while ciprofloxacin clearance was affected less."1.31Pharmacokinetics of levofloxacin and ciprofloxacin during continuous renal replacement therapy in critically ill patients. ( Abraham, E; Fish, DN; Malone, RS; Teitelbaum, I, 2001)
" These results suggest an increased bioavailability of ciprofloxacin in nephrectomized rats, which was confirmed by a nonlinear mixed-effect model."1.30Influence of renal failure on ciprofloxacin pharmacokinetics in rats. ( Carbon, C; Dautrey, S; Farinotti, R; Laouari, D; Nouaille-Degorce, B; Tod, M; Veau, C, 1998)
" After intravenous dosing of ciprofloxacin (10-30 mg kg(-1)), ciprofloxacin levels in plasma and brain were measured in normal rats (Wistar, male, 10-week-old) and those with acute renal and hepatic injuries which were induced by uranyl nitrate and carbon tetrachloride (CCl4), respectively."1.30Distribution of ciprofloxacin into the central nervous system in rats with acute renal or hepatic failure. ( Hirano, H; Ichikawa, N; Iwamoto, K; Naora, K, 1999)
"Percutaneous drainage of renal hydatid cysts is a safe and effective method for preventing renal loss, and decreasing morbidity and the duration of hospital stay."1.29Percutaneous drainage of renal hydatid cyst: early results and follow-up. ( Agarwal, MR; Goel, MC; Misra, A, 1995)
" The mean Cmax was 3."1.29Pharmacokinetics of ciprofloxacin in subjects with varying degrees of renal function and undergoing hemodialysis or CAPD. ( Bailie, GR; Echols, M; Kowalsky, SF; McCormick, E; Schwartz, MT, 1993)
"Oral ciprofloxacin therapy was continued for 10 days and the patient remained free of symptoms with formed stools thereafter."1.29Pseudomonas aeruginosa as a cause of infectious diarrhea successfully treated with oral ciprofloxacin. ( Porco, FV; Visconte, EB, 1995)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (50.00)18.2507
2000's5 (25.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cavallone, B1
Serao, A1
Audino, P1
Di Stasio, A1
Tiranti, D1
Vota, P1
Zaman, RA1
Ettenger, RB1
Cheam, H1
Malekzadeh, MH1
Tsai, EW1
Reisman, L1
Habib, S1
McClure, GB1
Latiolais, LS1
Vanchiere, JA1
Singh, N1
Gandhi, S1
McArthur, E1
Moist, L1
Jain, AK1
Liu, AR1
Sood, MM1
Garg, AX1
Cheng, MW1
Lee, CM1
Wang, NY1
Wu, AY1
Lin, CC1
Weng, LC1
Liu, CP1
Shih, SC1
Monescillo Francia, A1
Czock, D1
Rasche, FM1
Pea, F1
Poz, D1
Viale, P1
Pavan, F1
Furlanut, M1
Goel, MC1
Agarwal, MR1
Misra, A1
Xie, W1
Li, X1
Kowalsky, SF1
Echols, M1
Schwartz, MT1
Bailie, GR1
McCormick, E1
Porco, FV1
Visconte, EB1
Iakovlev, SV1
Iakovlev, VP1
Izotova, GN1
Jones, EM1
McMullin, CM1
Hedges, AJ1
Lovering, AM1
White, LO1
Reeves, DS1
MacGowan, AP1
Nouaille-Degorce, B1
Veau, C1
Dautrey, S2
Tod, M1
Laouari, D2
Carbon, C2
Farinotti, R2
Rabbaa, L1
Lacour, B1
Naora, K1
Ichikawa, N1
Hirano, H1
Iwamoto, K1
Lomaestro, BM1
Malone, RS1
Fish, DN1
Abraham, E1
Teitelbaum, I1
Dhawan, A1
Marwaha, RK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288]0 participants (Actual)Observational2015-09-30Withdrawn
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for ciprofloxacin and Kidney Failure

ArticleYear
[Pharmacokinetics of fluoroquinolones in patients with renal insufficiency].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1995, Volume: 40, Issue:10

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Ofloxacin; Pefloxacin; Quinolones; R

1995
Fluoroquinolone-induced renal failure.
    Drug safety, 2000, Volume: 22, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Renal Insufficiency

2000

Trials

1 trial available for ciprofloxacin and Kidney Failure

ArticleYear
The pharmacokinetics of intravenous ciprofloxacin 400 mg 12 hourly in patients with severe sepsis: the effect of renal function and intra-abdominal disease.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:1

    Topics: Abdomen; Adult; Aged; Bacteremia; Ciprofloxacin; Creatine; Dose-Response Relationship, Drug; Female;

1997

Other Studies

17 other studies available for ciprofloxacin and Kidney Failure

ArticleYear
Bilateral hydroureteronephrosis with renal failure caused by malacoplakia.
    Urologia, 2018, Volume: 85, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Ascorbic Acid; Ciprofloxacin; Female; Humans; Hydronephrosis; Malacopla

2018
A novel treatment regimen for BK viremia.
    Transplantation, 2014, Jun-15, Volume: 97, Issue:11

    Topics: Adolescent; BK Virus; Child; Ciprofloxacin; Female; Fluoroquinolones; Glomerular Filtration Rate; Hu

2014
Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child.
    Pediatric transplantation, 2014, Volume: 18, Issue:7

    Topics: Administration, Oral; Biopsy; BK Virus; Child, Preschool; Ciprofloxacin; Creatinine; Cytosine; DNA,

2014
Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2015, Jun-16, Volume: 187, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Ciprofl

2015
Clinical characteristics in adult patients with Salmonella bacteremia and analysis of ciprofloxacin-nonsusceptible isolates.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2015, Volume: 48, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; Base Sequence; beta-Lactamases;

2015
[Spontaneous bacterial peritonitis].
    Revista espanola de enfermedades digestivas, 2009, Volume: 101, Issue:9

    Topics: Anti-Bacterial Agents; Cefotaxime; Ciprofloxacin; Humans; Ofloxacin; Peritonitis; Primary Prevention

2009
Dose adjustment of ciprofloxacin in renal failure: reduce the dose or prolong the administration interval?
    European journal of medical research, 2005, Apr-20, Volume: 10, Issue:4

    Topics: Anti-Infective Agents; Area Under Curve; Ciprofloxacin; Computer Simulation; Dose-Response Relations

2005
Which reliable pharmacodynamic breakpoint should be advised for ciprofloxacin monotherapy in the hospital setting? A TDM-based retrospective perspective.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:2

    Topics: Analysis of Variance; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Chromatography,

2006
Percutaneous drainage of renal hydatid cyst: early results and follow-up.
    British journal of urology, 1995, Volume: 75, Issue:6

    Topics: Adult; Albendazole; Ciprofloxacin; Drainage; Echinococcosis; Female; Follow-Up Studies; Humans; Kidn

1995
Experience in treating secondary systemic mycotic infection after severe burns associated with electric injury.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1995, Volume: 10, Issue:1

    Topics: Adult; Amputation, Surgical; Burns, Electric; Candidiasis; Ciprofloxacin; Fluconazole; Humans; Male;

1995
Pharmacokinetics of ciprofloxacin in subjects with varying degrees of renal function and undergoing hemodialysis or CAPD.
    Clinical nephrology, 1993, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Ciprofloxacin; Female; Half-Life; Humans; Least-Squares Analysis; Male;

1993
Pseudomonas aeruginosa as a cause of infectious diarrhea successfully treated with oral ciprofloxacin.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:11

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Cross Infection

1995
Influence of renal failure on ciprofloxacin pharmacokinetics in rats.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:2

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Ciprofloxacin; Infusions, Parenteral; Kidney;

1998
Influence of renal failure on intestinal clearance of ciprofloxacin in rats.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3

    Topics: Animals; Anti-Infective Agents; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Ciprof

1999
Distribution of ciprofloxacin into the central nervous system in rats with acute renal or hepatic failure.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:5

    Topics: Animals; Anti-Infective Agents; Central Nervous System; Ciprofloxacin; Liver Failure; Male; Rats; Ra

1999
Pharmacokinetics of levofloxacin and ciprofloxacin during continuous renal replacement therapy in critically ill patients.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:10

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Critical Illness; Female; Hemofiltration; Humans;

2001
Acute glomerulonephritis in multi-drug resistant Salmonella typhi infection.
    Indian pediatrics, 1992, Volume: 29, Issue:8

    Topics: Blood Chemical Analysis; Child; Ciprofloxacin; Fever; Glomerulonephritis; Humans; Male; Peritoneal D

1992