ciprofloxacin has been researched along with Hypotension in 4 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, concomitant use of tizanidine with ciprofloxacin, a strong inhibitor of the P450-CYP1A2 cytochrome metabolic pathway of tizanidine, can result in increased tizanidine plasma levels and associated adverse outcomes, particularly hypotension." | 4.12 | Risk of tizanidine-induced adverse events after concomitant exposure to ciprofloxacin: A cohort study in the U.S. ( Giannouchos, TV; Gómez-Lumbreras, A; Malone, DC, 2022) |
| " Some of the important safety signals included interactions between tizanidine in a suspect or interacting role and ciprofloxacin (ROR for hypotension 28." | 4.12 | A Disproportionality Analysis of Drug-Drug Interactions of Tizanidine and CYP1A2 Inhibitors from the FDA Adverse Event Reporting System (FAERS). ( Boyce, RD; Gómez-Lumbreras, A; Horn, J; Malone, DC; Tan, MS; Villa-Zapata, L, 2022) |
| "Suspecting typhoid fever with ciprofloxacin was started." | 3.71 | [Fever and calf tenderness after travel in Thailand: murine typhus and deep vein thrombosis]. ( Döller, PC; Slesak, G, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giannouchos, TV | 1 |
| Gómez-Lumbreras, A | 2 |
| Malone, DC | 2 |
| Villa-Zapata, L | 1 |
| Horn, J | 1 |
| Tan, MS | 1 |
| Boyce, RD | 1 |
| Raza, A | 1 |
| Qawi, H | 1 |
| Lisak, L | 1 |
| Andric, T | 1 |
| Dar, S | 1 |
| Andrews, C | 1 |
| Venugopal, P | 1 |
| Gezer, S | 1 |
| Gregory, S | 1 |
| Loew, J | 1 |
| Robin, E | 1 |
| Rifkin, S | 1 |
| Hsu, WT | 1 |
| Huang, RW | 1 |
| Slesak, G | 1 |
| Döller, PC | 1 |
4 other studies available for ciprofloxacin and Hypotension
| Article | Year |
|---|---|
Risk of tizanidine-induced adverse events after concomitant exposure to ciprofloxacin: A cohort study in the U.S.
Topics: Ciprofloxacin; Clonidine; Cohort Studies; Drug Interactions; Female; Humans; Hypotension; Middle Age | 2022 |
A Disproportionality Analysis of Drug-Drug Interactions of Tizanidine and CYP1A2 Inhibitors from the FDA Adverse Event Reporting System (FAERS).
Topics: Adverse Drug Reaction Reporting Systems; Ciprofloxacin; Clonidine; Cytochrome P-450 CYP1A2; Cytochro | 2022 |
Patients with myelodysplastic syndromes benefit from palliative therapy with amifostine, pentoxifylline, and ciprofloxacin with or without dexamethasone.
Topics: Adult; Aged; Aged, 80 and over; Amifostine; Anorexia; Antineoplastic Combined Chemotherapy Protocols | 2000 |
[Fever and calf tenderness after travel in Thailand: murine typhus and deep vein thrombosis].
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Dehydration; Fever; Fibrinolytic Agents; Germany; Hepar | 2001 |