Page last updated: 2024-10-25

ciprofloxacin and Hypoglycemia

ciprofloxacin has been researched along with Hypoglycemia in 12 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.

Research Excerpts

ExcerptRelevanceReference
"A search was made on the World Health Organization global adverse drug reaction database (August 15, 2018) using "ciprofloxacin" as the drug substance and "hypoglycemia" as the reaction term."3.91Ciprofloxacin and risk of hypolycemia in non-diabetic patients. ( Bahran, F; Berhe, A; Hagos, G; Russom, M, 2019)
"To determine the risk of hypoglycemia and associated costs in older patients prescribed glipizide or glyburide who fill a prescription for an antimicrobial drug."3.80Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas. ( Goodwin, JS; Kuo, YF; Lin, YL; Parekh, TM; Raji, M; Tan, A, 2014)
" The risk of hypoglycemia varied according to the type of fluoroquinolone administered, and was most commonly associated with moxifloxacin."3.79Risk of severe dysglycemia among diabetic patients receiving levofloxacin, ciprofloxacin, or moxifloxacin in Taiwan. ( Chang, CH; Chou, HW; Lai, MS; Lee, JJ; Shau, WY; Wang, JL, 2013)
" On the other hand, ciprofloxacin, which is widely used in the treatment of infectious diseases, is known to cause hypoglycemia as a side effect."3.74[Influence of tacrolimus and ciprofloxacin on glucose metabolism]. ( Arai, S; Gouhara, T; Kihira, K; Kitaura, T; Miyake, K; Morita, S; Nagafuji, T; Sato, E; Tayama, Y, 2007)
"Population-based data are needed to inform the safe prescribing of fluoroquinolone antibiotics to patients with advanced chronic kidney disease (CKD)."1.72Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease. ( Ahmadi, F; Garg, AX; Kim, RB; Knoll, GA; Muanda, FT; Silverman, MS; Sontrop, JM; Sood, MM; Weir, MA; Yoo, E, 2022)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Muanda, FT1
Sood, MM1
Weir, MA1
Sontrop, JM1
Ahmadi, F1
Yoo, E1
Kim, RB1
Silverman, MS1
Knoll, GA1
Garg, AX1
Berhe, A1
Russom, M1
Bahran, F1
Hagos, G1
Chou, HW1
Wang, JL1
Chang, CH1
Lee, JJ1
Shau, WY1
Lai, MS1
Parekh, TM1
Raji, M1
Lin, YL1
Tan, A1
Kuo, YF1
Goodwin, JS1
Kelesidis, T1
Canseco, E1
Vinh, H1
Anh, VT1
Anh, ND1
Campbell, JI1
Hoang, NV1
Nga, TV1
Nhu, NT1
Minh, PV1
Thuy, CT1
Duy, PT1
Phuong, le T1
Loan, HT1
Chinh, MT1
Thao, NT1
Tham, NT1
Mong, BL1
Bay, PV1
Day, JN1
Dolecek, C1
Lan, NP1
Diep, TS1
Farrar, JJ1
Chau, NV1
Wolbers, M1
Baker, S1
Lin, G1
Hays, DP1
Spillane, L1
Roberge, R1
Mohr, JF1
McKinnon, PS1
Peymann, PJ1
Kenton, I1
Septimus, E1
Okhuysen, PC1
Catero, M1
Tayama, Y1
Miyake, K1
Nagafuji, T1
Gouhara, T1
Morita, S1
Arai, S1
Sato, E1
Kitaura, T1
Kihira, K1
Roberge, RJ1
Kaplan, R1
Frank, R1
Fore, C1

Reviews

1 review available for ciprofloxacin and Hypoglycemia

ArticleYear
Dysglycemia and fluoroquinolones: are you putting patients at risk?
    The Journal of family practice, 2007, Volume: 56, Issue:2

    Topics: Adolescent; Adult; Aza Compounds; Bacterial Infections; Blood Glucose; Ciprofloxacin; Dose-Response

2007

Trials

1 trial available for ciprofloxacin and Hypoglycemia

ArticleYear
A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children.
    PLoS neglected tropical diseases, 2011, Volume: 5, Issue:8

    Topics: Anti-Bacterial Agents; Child, Preschool; Ciprofloxacin; Dysentery, Bacillary; Feces; Female; Fluoroq

2011

Other Studies

10 other studies available for ciprofloxacin and Hypoglycemia

ArticleYear
Association of Higher-Dose Fluoroquinolone Therapy With Serious Adverse Events in Older Adults With Advanced Chronic Kidney Disease.
    JAMA network open, 2022, 08-01, Volume: 5, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Cohort Studies; Death, Sudden, Cardia

2022
Ciprofloxacin and risk of hypolycemia in non-diabetic patients.
    Journal of medical case reports, 2019, May-12, Volume: 13, Issue:1

    Topics: Adult; Blood Glucose; Ciprofloxacin; Humans; Hypoglycemia; Male; Urinary Tract Infections

2019
Risk of severe dysglycemia among diabetic patients receiving levofloxacin, ciprofloxacin, or moxifloxacin in Taiwan.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 57, Issue:7

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Cohort Studies; Diabet

2013
Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas.
    JAMA internal medicine, 2014, Volume: 174, Issue:10

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Drug Interactions; Dr

2014
Quinolone-induced hypoglycemia: a life-threatening but potentially reversible side effect.
    The American journal of medicine, 2010, Volume: 123, Issue:2

    Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Type 2; Female; Gastrointestinal Agen

2010
Refractory hypoglycemia from ciprofloxacin and glyburide interaction.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:3

    Topics: Aged; Anti-Infective Agents; Blood Glucose; Ciprofloxacin; Diabetes Mellitus, Type 2; Diet; Drug Int

2004
Comment on "refractory hypoglycemia from ciprofloxacin and glyburide interaction".
    Clinical toxicology (Philadelphia, Pa.), 2005, Volume: 43, Issue:3

    Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relati

2005
A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone.
    Pharmacotherapy, 2005, Volume: 25, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Blood Glucose; Ceftriaxone; Ciprofloxacin; Fe

2005
[Influence of tacrolimus and ciprofloxacin on glucose metabolism].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2007, Volume: 127, Issue:11

    Topics: Animals; Anti-Infective Agents; Body Weight; Cell Survival; Cells, Cultured; Ciprofloxacin; Cricetin

2007
Glyburide-ciprofloxacin interaction with resistant hypoglycemia.
    Annals of emergency medicine, 2000, Volume: 36, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Diabetes Mellitus, Type 2; Diabetic N

2000