Page last updated: 2024-10-25

ciprofloxacin and Hepatorenal Syndrome

ciprofloxacin has been researched along with Hepatorenal Syndrome in 1 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Hepatorenal Syndrome: Functional KIDNEY FAILURE in patients with liver disease, usually LIVER CIRRHOSIS or portal hypertension (HYPERTENSION, PORTAL), and in the absence of intrinsic renal disease or kidney abnormality. It is characterized by intense renal vasculature constriction, reduced renal blood flow, OLIGURIA, and sodium retention.

Research Excerpts

ExcerptRelevanceReference
"To compare an intravenous-oral step-down schedule with ciprofloxacin (switch therapy) to intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis, and to evaluate the impact of terlipressin and albumin in the treatment of type 1 hepatorenal syndrome on mortality."9.12Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost. ( Angeli, P; Antona, C; Brollo, L; Cillo, U; Craighero, R; Fasolato, S; Franchin, M; Gatta, A; Guarda, S; Merkel, C; Miola, E; Piccolo, F, 2006)
"To compare an intravenous-oral step-down schedule with ciprofloxacin (switch therapy) to intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis, and to evaluate the impact of terlipressin and albumin in the treatment of type 1 hepatorenal syndrome on mortality."5.12Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost. ( Angeli, P; Antona, C; Brollo, L; Cillo, U; Craighero, R; Fasolato, S; Franchin, M; Gatta, A; Guarda, S; Merkel, C; Miola, E; Piccolo, F, 2006)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Angeli, P1
Guarda, S1
Fasolato, S1
Miola, E1
Craighero, R1
Piccolo, F1
Antona, C1
Brollo, L1
Franchin, M1
Cillo, U1
Merkel, C1
Gatta, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Terlipressin Given As I.V. Boluses Vs Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome (Hrs): Preliminary Results Of A Randomized Controlled Clinical Study.[NCT00742690]Phase 2/Phase 370 participants (Anticipated)Interventional2005-05-31Recruiting
Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis: an Open, Randomized, Controlled Clinical Trial[NCT01455246]Phase 2/Phase 332 participants (Actual)Interventional2010-10-31Terminated (stopped due to Decision of independent monitoring committee after interim analysis: Risk of failure significantly higher in ceftazidime group.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ciprofloxacin and Hepatorenal Syndrome

ArticleYear
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006