Page last updated: 2024-10-25

ciprofloxacin and Hemolysis

ciprofloxacin has been researched along with Hemolysis in 37 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia."7.72Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia. ( Alam, MG; Lim, S, 2003)
"Our study indicated the inhibitory effect of ciprofloxacin and ceftriaxone on the level of hemolysis, suggesting that the sub-inhibitory concentrations of these antibiotics may affect the outcome of infections."4.12Characterization of Escherichia coli isolated from urinary tract infection and association between virulence expression and antimicrobial susceptibility. ( Aghaei, A; Ahmadi, E; Ahmadi, S; Derakhshan, S; Nasseri, S, 2022)
"Ciprofloxacin has been associated with several side effects including interstitial nephritis and hemolytic anemia."3.72Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia. ( Alam, MG; Lim, S, 2003)
" Moreover, the cytotoxicity results against L929 fibroblast cell line revealed that p(ML) based particle are biocompatible up to 100 μg/mL with 85% cell viability regardless of their nature, and at 200 μg/mL dosage of p(ML), m-p(ML)/TA and m-p(ML)/DETA particles, the cell viabilities were determined as 83."1.48One step preparation of polymeric maltitol particles, from a sugar molecule, maltitol for biomedical applications. ( Sahiner, N, 2018)
"PVP-CD was proved safe and demonstrated excellent biocompatibility, healing and degradation properties."1.38Safety, healing, and efficacy of vascular prostheses coated with hydroxypropyl-β-cyclodextrin polymer: experimental in vitro and animal studies. ( Blanchemain, N; Haulon, S; Hildebrand, HF; Jean-Baptiste, E; Martel, B; Neut, C, 2012)
"Ophthalmic delivery systems such as ocular inserts are useful strategies to improve the ocular bioavailability of topically administered drugs."1.36Biodegradable hybrid polymeric membranes for ocular drug delivery. ( Banerjee, R; Carvalho, E; Jain, D, 2010)
"Ciprofloxacin resistance was identified in 18% and 6% of consecutively collected, clinically significant urinary tract isolates of Escherichia coli from inpatients and outpatients, respectively."1.33Decreased prevalence of virulence factors among ciprofloxacin-resistant uropathogenic Escherichia coli isolates. ( Drews, SJ; Green, K; Low, DE; Mazzulli, T; McGeer, AJ; Pong-Porter, S; Poutanen, SM; Rzayev, Y; Sarabia, A; Willey, B, 2005)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (13.51)18.2507
2000's5 (13.51)29.6817
2010's22 (59.46)24.3611
2020's5 (13.51)2.80

Authors

AuthorsStudies
Nielsen, SF1
Larsen, M1
Boesen, T1
Schønning, K1
Kromann, H1
Zaknoon, F1
Sarig, H1
Rotem, S1
Livne, L1
Ivankin, A1
Gidalevitz, D1
Mor, A1
Abdel-Wahab, BF1
Awad, GE1
Badria, FA1
Singh, MK1
Tilak, R2
Nath, G2
Awasthi, SK2
Agarwal, A2
Lohan, S2
Cameotra, SS1
Bisht, GS1
Fardeau, S1
Dassonville-Klimpt, A1
Audic, N1
Sasaki, A1
Pillon, M1
Baudrin, E1
Mullié, C1
Sonnet, P1
Chugunova, E1
Akylbekov, N1
Bulatova, A1
Gavrilov, N1
Voloshina, A1
Kulik, N1
Zobov, V1
Dobrynin, A1
Syakaev, V1
Burilov, A1
Kant, R1
Singh, V1
Dou, X2
Zhu, X1
Wang, J2
Dong, N1
Shan, A3
Lyu, Y1
Yang, X2
Goswami, S1
Gorityala, BK1
Idowu, T1
Domalaon, R1
Zhanel, GG1
Schweizer, F1
Sharma, KK1
Maurya, IK1
Khan, SI1
Jacob, MR1
Kumar, V1
Tikoo, K1
Jain, R1
Chou, S1
Yang, Z1
Yang, Y1
Wang, Z1
Song, J1
Dias, FRF1
Novais, JS1
Devillart, TADNS1
da Silva, WA1
Ferreira, MO1
Loureiro, RS1
Campos, VR1
Ferreira, VF1
de Souza, MCBV1
Castro, HC1
Cunha, AC1
Qiu, Y1
Chan, ST1
Lin, L1
Shek, TL1
Tsang, TF1
Barua, N1
Zhang, Y1
Ip, M1
Chan, PK1
Blanchard, N1
Hanquet, G1
Zuo, Z1
Ma, C1
Zhang, PL1
Gopala, L1
Zhang, SL1
Cai, GX1
Zhou, CH1
Mandal, D1
Choi, W1
Konshina, AG1
Tiwari, RK1
Efremov, RG1
Maslennikov, I1
Parang, K1
Langer, MK1
Rahman, A1
Dey, H1
Anderssen, T1
Zilioli, F1
Haug, T1
Blencke, HM1
Stensvåg, K1
Strøm, MB1
Bayer, A1
Derakhshan, S1
Ahmadi, S1
Ahmadi, E1
Nasseri, S1
Aghaei, A1
Aziz-Ur-Rehman, -1
Khan, SG1
Bokhari, TH1
Anjum, F1
Akhter, N1
Rasool, S1
Ali Shah, SA1
Shahid, M2
Arshad, A1
Sahiner, N1
Abbasi, MA1
Nazeer, MM1
Rehman, A1
Siddiqui, SZ1
Hussain, G1
Shah, SA1
Ahmad, I1
Sarwar, MS1
Patel, KK1
Tripathi, M1
Pandey, N1
Agrawal, AK1
Gade, S1
Anjum, MM1
Singh, S1
Singh, M1
Gadepalli, R1
Dhawan, B1
Mukhopadhyay, K1
Skwor, T1
Shinko, J1
Augustyniak, A1
Gee, C1
Andraso, G1
Šišková, P1
Černohorská, L1
Mahelová, M1
Turková, K1
Woznicová, V1
Singh, B1
Varshney, L1
Sharma, V1
Jain, D1
Carvalho, E1
Banerjee, R1
Jean-Baptiste, E1
Blanchemain, N1
Martel, B1
Neut, C1
Hildebrand, HF1
Haulon, S1
Seas, C1
Villaverde, H1
Maguiña, C1
Lim, S1
Alam, MG1
Drews, SJ1
Poutanen, SM1
Mazzulli, T1
McGeer, AJ1
Sarabia, A1
Pong-Porter, S1
Rzayev, Y1
Willey, B1
Green, K1
Low, DE1
Soto, SM1
Jimenez de Anta, MT1
Vila, J1
Flynn, MJ1
Slots, J1
Andrews, PA1
Robinson, GT1
Martínez-Martínez, L1
Fernández, F1
Perea, EJ1
Robertson, DG1
Epling, GA1
Kiely, JS1
Bailey, DL1
Song, B1
Ferguson, J1
Johnson, BE1

Other Studies

37 other studies available for ciprofloxacin and Hemolysis

ArticleYear
Cationic chalcone antibiotics. Design, synthesis, and mechanism of action.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Bacterial Agents; Cations; Chalcones; Colony Count, Microbial; Drug Design; Hemolysis; Humans;

2005
Antibacterial properties and mode of action of a short acyl-lysyl oligomer.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:8

    Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Membrane; Erythrocytes; Escherichia col

2009
Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Bacteria; Cell Proliferation; D

2011
Design, synthesis and antimicrobial activity of novel benzothiazole analogs.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Anti-Bacterial Agents; Antifungal Agents; Benzothiazoles; Click Chemistry; Drug Design; Fungi; Gram-

2013
Antibacterial evaluation of structurally amphipathic, membrane active small cationic peptidomimetics: synthesized by incorporating 3-amino benzoic acid as peptidomimetic element.
    European journal of medicinal chemistry, 2014, Aug-18, Volume: 83

    Topics: Anti-Bacterial Agents; Benzoic Acid; Cell Line; Cell Membrane; Drug Design; Drug Resistance, Bacteri

2014
Synthesis and antibacterial activity of catecholate-ciprofloxacin conjugates.
    Bioorganic & medicinal chemistry, 2014, Aug-01, Volume: 22, Issue:15

    Topics: Anti-Bacterial Agents; Catechols; Ciprofloxacin; Erythrocytes; Hemolysis; Humans; Iron Chelating Age

2014
Synthesis and biological evaluation of novel structural hybrids of benzofuroxan derivatives and fluoroquinolones.
    European journal of medicinal chemistry, 2016, Jun-30, Volume: 116

    Topics: Anti-Bacterial Agents; Bacteria; Benzoxazoles; Chemistry Techniques, Synthetic; Drug Design; Fluoroq

2016
Design, synthesis and biological evaluation of ciprofloxacin tethered bis-1,2,3-triazole conjugates as potent antibacterial agents.
    European journal of medicinal chemistry, 2016, Nov-29, Volume: 124

    Topics: Anti-Bacterial Agents; Chemistry Techniques, Synthetic; Ciprofloxacin; Drug Design; Gram-Negative Ba

2016
Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biofilms; Circular Dichr

2017
Amphiphilic Tobramycin-Lysine Conjugates Sensitize Multidrug Resistant Gram-Negative Bacteria to Rifampicin and Minocycline.
    Journal of medicinal chemistry, 2017, 05-11, Volume: 60, Issue:9

    Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive B

2017
Discovery of a Membrane-Active, Ring-Modified Histidine Containing Ultrashort Amphiphilic Peptide That Exhibits Potent Inhibition of Cryptococcus neoformans.
    Journal of medicinal chemistry, 2017, 08-10, Volume: 60, Issue:15

    Topics: Amphotericin B; Animals; Antifungal Agents; Biphenyl Compounds; Cell Line, Tumor; Cell Membrane; Chl

2017
Combating Drug-Resistant Fungi with Novel Imperfectly Amphipathic Palindromic Peptides.
    Journal of medicinal chemistry, 2018, 05-10, Volume: 61, Issue:9

    Topics: Amino Acid Sequence; Animals; Antifungal Agents; Candida albicans; Cytoplasm; Drug Resistance, Funga

2018
Synthesis and antimicrobial evaluation of amino sugar-based naphthoquinones and isoquinoline-5,8-diones and their halogenated compounds.
    European journal of medicinal chemistry, 2018, Aug-05, Volume: 156

    Topics: Amino Sugars; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Halogenation; Hemolysis; Humans

2018
Design, synthesis and biological evaluation of antimicrobial diarylimine and -amine compounds targeting the interaction between the bacterial NusB and NusE proteins.
    European journal of medicinal chemistry, 2019, Sep-15, Volume: 178

    Topics: Aniline Compounds; Anti-Bacterial Agents; Bacterial Proteins; Benzylamines; Caco-2 Cells; Drug Desig

2019
An unanticipated discovery towards novel naphthalimide corbelled aminothiazoximes as potential anti-MRSA agents and allosteric modulators for PBP2a.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Allosteric Regulation; Allosteric Site; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Dr

2022
Small Amphiphilic Peptides: Activity Against a Broad Range of Drug-Resistant Bacteria and Structural Insight into Membranolytic Properties.
    Journal of medicinal chemistry, 2022, 01-13, Volume: 65, Issue:1

    Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteria; Cell Membrane; Cell Survival; Drug

2022
A concise SAR-analysis of antimicrobial cationic amphipathic barbiturates for an improved activity-toxicity profile.
    European journal of medicinal chemistry, 2022, Nov-05, Volume: 241

    Topics: Amines; Anti-Bacterial Agents; Anti-Infective Agents; Barbiturates; Cations; Gram-Negative Bacteria;

2022
Characterization of Escherichia coli isolated from urinary tract infection and association between virulence expression and antimicrobial susceptibility.
    BMC microbiology, 2022, 04-06, Volume: 22, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Ciprofloxacin; Escherichia coli; Escherichia coli Infec

2022
Synthesis, characterization, antibacterial, hemolytic and thrombolytic activity evaluation of 5-(3-chlorophenyl)-2-((N-(substituted)-2-acetamoyl)sulfanyl)-1,3,4-oxadiazole derivatives.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:2(Suppleme

    Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Fibrinolytic Agents; Hemolysis; Microbial Sensitivit

2020
One step preparation of polymeric maltitol particles, from a sugar molecule, maltitol for biomedical applications.
    Materials science & engineering. C, Materials for biological applications, 2018, Aug-01, Volume: 89

    Topics: Animals; Biocompatible Materials; Blood Coagulation; Cell Line; Cell Survival; Chromosomes; Ciproflo

2018
Synthesis of 2-Furyl[(4-aralkyl)-1-piperazinyl]methanone derivatives as suitable antibacterial agents with mild cytotoxicity.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cattle; Ciprofloxacin; Gr

2018
Alginate lyase immobilized chitosan nanoparticles of ciprofloxacin for the improved antimicrobial activity against the biofilm associated mucoid P. aeruginosa infection in cystic fibrosis.
    International journal of pharmaceutics, 2019, May-30, Volume: 563

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Chitosan; Ciprofloxacin; Cystic Fibrosis; Drug Liberation;

2019
Combination of alpha-melanocyte stimulating hormone with conventional antibiotics against methicillin resistant Staphylococcus aureus.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: 3T3 Cells; alpha-MSH; Animals; Anti-Bacterial Agents; Bacterial Proteins; Cell Survival; Ciprofloxac

2013
Aeromonas hydrophila and Aeromonas veronii predominate among potentially pathogenic ciprofloxacin- and tetracycline-resistant aeromonas isolates from Lake Erie.
    Applied and environmental microbiology, 2014, Volume: 80, Issue:3

    Topics: Aeromonas; Anti-Bacterial Agents; Cell Survival; Ciprofloxacin; DNA Gyrase; Drug Resistance, Bacteri

2014
Phenotypes of Escherichia coli isolated from urine: Differences between extended-spectrum β-lactamase producers and sensitive strains.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2015, Volume: 48, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Typing Techniques; beta

2015
Design of sterile mucoadhesive hydrogels for use in drug delivery: effect of radiation on network structure.
    Colloids and surfaces. B, Biointerfaces, 2014, Sep-01, Volume: 121

    Topics: Adhesives; Animals; Ciprofloxacin; Differential Thermal Analysis; Diffusion; Drug Delivery Systems;

2014
Biodegradable hybrid polymeric membranes for ocular drug delivery.
    Acta biomaterialia, 2010, Volume: 6, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Carboxymethylcellulose Sodium; Cell Line; C

2010
Safety, healing, and efficacy of vascular prostheses coated with hydroxypropyl-β-cyclodextrin polymer: experimental in vitro and animal studies.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2012, Volume: 43, Issue:2

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Anti-Bacterial Agents; beta-Cyclodextrins; Blood Vessel

2012
A 60-year-old man from the highlands of Peru with fever and hemolysis.
    The American journal of tropical medicine and hygiene, 2012, Volume: 86, Issue:3

    Topics: Anemia; Bartonella bacilliformis; Bartonella Infections; Ceftriaxone; Ciprofloxacin; Fever; Hemolysi

2012
Ciprofloxacin-induced acute interstitial nephritis and autoimmune hemolytic anemia.
    Renal failure, 2003, Volume: 25, Issue:4

    Topics: Acute Disease; Aged; Anemia, Hemolytic, Autoimmune; Anti-Infective Agents; Ciprofloxacin; Glucosepho

2003
Decreased prevalence of virulence factors among ciprofloxacin-resistant uropathogenic Escherichia coli isolates.
    Journal of clinical microbiology, 2005, Volume: 43, Issue:8

    Topics: Bacteriuria; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Hemolysis; Humans; Nalidix

2005
Quinolones induce partial or total loss of pathogenicity islands in uropathogenic Escherichia coli by SOS-dependent or -independent pathways, respectively.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:2

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field

2006
Beta-hemolytic streptococci in advanced periodontitis.
    Oral microbiology and immunology, 1993, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Ciprofloxacin; Colony Count, Microbial; Cross-Sectional Studie

1993
Intravascular haemolysis and interstitial nephritis in association with ciprofloxacin.
    Nephron, 1999, Volume: 83, Issue:4

    Topics: Anemia, Hemolytic; Anti-Infective Agents; Ciprofloxacin; Female; Hemolysis; Humans; Middle Aged; Nep

1999
Relationship between haemolysis production and resistance to fluoroquinolones among clinical isolates of Escherichia coli.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:2

    Topics: Amoxicillin; Ampicillin; Animals; Anti-Infective Agents; Ciprofloxacin; Clavulanic Acid; Drug Resist

1999
Mechanistic studies of the phototoxic potential of PD 117596, a quinolone antibacterial compound.
    Toxicology and applied pharmacology, 1991, Volume: 111, Issue:2

    Topics: 4-Quinolones; Animals; Anti-Infective Agents; Antioxidants; Ciprofloxacin; Dose-Response Relationshi

1991
Ciprofloxacin-induced photosensitivity: in vitro and in vivo studies.
    The British journal of dermatology, 1990, Volume: 123, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Candida albicans; Cells, Cultured; Ciprofloxacin; DNA; Fema

1990