Page last updated: 2024-10-25

ciprofloxacin and Fibrosis

ciprofloxacin has been researched along with Fibrosis in 8 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"Ciprofloxacin (CIP) has poor lung targeting after oral inhalation."5.62Development of Inhalable Nanostructured Lipid Carriers for Ciprofloxacin for Noncystic Fibrosis Bronchiectasis Treatment. ( Aldosari, BN; Alfagih, IM; Aljunaidel, HA; Almarshidy, SS; Almurshedi, AS; Alquadeib, B; Eltahir, EKD; Mohamoud, AZ, 2021)
" To determine if oral ciprofloxacin reduces the severity of scleroderma, a controlled, double-blind randomized clinical trial, with placebo, was conducted on 32 patients with diffuse and limited scleroderma, who received oral ciprofloxacin (250 mg) or placebo every 12 h."5.14Ciprofloxacin utility as antifibrotic in the skin of patients with scleroderma. ( Agustín, OR; Antonio, FM; Huerta, M; Iván, DE; Manuel, VR; Rubén, EC, 2010)
"7%), fibrosis was significantly reduced in the pentoxifylline- and ciprofloxacin-treated groups (4."3.70Effect of preoperative interventions on outcome following liver resection in a rat model of cirrhosis. ( Gong, Y; Johnson, J; Kneteman, N; Minuk, GY; Moser, M; Zhang, M, 2000)
"A total of 150 patients with COPD, non-CF bronchiectasis or asthma, and P."3.11Targeted AntiBiotics for Chronic pulmonary diseases (TARGET ABC): can targeted antibiotic therapy improve the prognosis of Pseudomonas aeruginosa-infected patients with chronic pulmonary obstructive disease, non-cystic fibrosis bronchiectasis, and asthma? ( Alispahic, IA; Andreassen, HF; Armbruster, K; Bangsborg, J; Bodtger, U; Browatzki, A; Christensen, CW; Coia, JE; Datcu, R; Eklöf, J; Ellingsgaard, T; Fenlev, CS; Ghathian, KSA; Gundersen, L; Harboe, ZB; Heidemann, M; Janner, J; Jensen, JUS; Jensen, TT; Johansson, SL; Johnsen, S; Kjærgaard, JL; Lapperre, TS; Linde, H; Moberg, M; Nielsen, TL; Overgaard, RH; Pedersen, L; Rosenvinge, FS; Saeed, MI; Seersholm, N; Sivapalan, P; Sørensen, VM; Titlestad, I; Ulrik, CS; Vijdea, R; Weinreich, UM; Wilcke, T; Østergaard, C, 2022)
"Bacterial infections are common in cirrhotic patients with acute variceal bleeding, occurring in 20% within 48 h."2.50Role of prophylactic antibiotics in cirrhotic patients with variceal bleeding. ( Lee, YY; Mahadeva, S; Tee, HP, 2014)
"Ciprofloxacin (CIP) has poor lung targeting after oral inhalation."1.62Development of Inhalable Nanostructured Lipid Carriers for Ciprofloxacin for Noncystic Fibrosis Bronchiectasis Treatment. ( Aldosari, BN; Alfagih, IM; Aljunaidel, HA; Almarshidy, SS; Almurshedi, AS; Alquadeib, B; Eltahir, EKD; Mohamoud, AZ, 2021)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Eklöf, J1
Alispahic, IA1
Sivapalan, P1
Wilcke, T1
Seersholm, N1
Armbruster, K1
Kjærgaard, JL1
Saeed, MI1
Nielsen, TL1
Browatzki, A1
Overgaard, RH1
Fenlev, CS1
Harboe, ZB1
Andreassen, HF1
Lapperre, TS1
Pedersen, L1
Johnsen, S1
Ulrik, CS1
Janner, J1
Moberg, M1
Heidemann, M1
Weinreich, UM1
Vijdea, R1
Linde, H1
Titlestad, I1
Johansson, SL1
Rosenvinge, FS1
Østergaard, C1
Ghathian, KSA1
Gundersen, L1
Christensen, CW1
Bangsborg, J1
Jensen, TT1
Sørensen, VM1
Ellingsgaard, T1
Datcu, R1
Coia, JE1
Bodtger, U1
Jensen, JUS1
Almurshedi, AS1
Aljunaidel, HA1
Alquadeib, B1
Aldosari, BN1
Alfagih, IM1
Almarshidy, SS1
Eltahir, EKD1
Mohamoud, AZ1
Grimwood, K1
Chang, AB1
Lee, YY1
Tee, HP1
Mahadeva, S1
Rubén, EC1
Manuel, VR1
Agustín, OR1
Huerta, M1
Antonio, FM1
Iván, DE1
Caliskan, B1
Guven, A1
Ozler, M1
Cayci, T1
Ozcan, A1
Bedir, O1
Surer, I1
Korkmaz, A1
Gomes-Filho, JE1
Duarte, PC1
de Oliveira, CB1
Watanabe, S1
Lodi, CS1
Cintra, LT1
Bernabé, PF1
Moser, M1
Zhang, M1
Gong, Y1
Johnson, J1
Kneteman, N1
Minuk, GY1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Targeted AntiBiotics for Chronic Pulmonary Disease: Can Targeted Antibiotic Therapy Improve the Prognosis of Pseudomonas Aeruginosa Infected Patients With Chronic Pulmonary Obstructive Disease, Non-cystic Fibrosis Bronchiectasis and Asthma? A Multicenter,[NCT03262142]Phase 451 participants (Actual)Interventional2018-01-10Terminated (stopped due to Slow recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ciprofloxacin and Fibrosis

ArticleYear
Role of prophylactic antibiotics in cirrhotic patients with variceal bleeding.
    World journal of gastroenterology, 2014, Feb-21, Volume: 20, Issue:7

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciprofloxacin; Endoscopy; Esoph

2014

Trials

2 trials available for ciprofloxacin and Fibrosis

ArticleYear
Targeted AntiBiotics for Chronic pulmonary diseases (TARGET ABC): can targeted antibiotic therapy improve the prognosis of Pseudomonas aeruginosa-infected patients with chronic pulmonary obstructive disease, non-cystic fibrosis bronchiectasis, and asthma?
    Trials, 2022, Sep-27, Volume: 23, Issue:1

    Topics: Anti-Bacterial Agents; Asthma; beta-Lactams; Bronchiectasis; Ciprofloxacin; Fibrosis; Humans; Predni

2022
Ciprofloxacin utility as antifibrotic in the skin of patients with scleroderma.
    The Journal of dermatology, 2010, Volume: 37, Issue:4

    Topics: Administration, Oral; Adult; Ciprofloxacin; Female; Fibrosis; Humans; Kidney; Liver; Male; Middle Ag

2010

Other Studies

5 other studies available for ciprofloxacin and Fibrosis

ArticleYear
Development of Inhalable Nanostructured Lipid Carriers for Ciprofloxacin for Noncystic Fibrosis Bronchiectasis Treatment.
    International journal of nanomedicine, 2021, Volume: 16

    Topics: Administration, Inhalation; Anti-Bacterial Agents; Bronchiectasis; Chitosan; Ciprofloxacin; Drug Car

2021
A new dawn: inhaled antibiotics for patients with bronchiectasis.
    The Lancet. Respiratory medicine, 2019, Volume: 7, Issue:3

    Topics: Anti-Bacterial Agents; Bronchiectasis; Ciprofloxacin; Fibrosis; Humans; Pseudomonas aeruginosa

2019
Ozone therapy prevents renal inflammation and fibrosis in a rat model of acute pyelonephritis.
    Scandinavian journal of clinical and laboratory investigation, 2011, Volume: 71, Issue:6

    Topics: Acute Disease; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Calcitonin; Ciprofloxaci

2011
Tissue reaction to a triantibiotic paste used for endodontic tissue self-regeneration of nonvital immature permanent teeth.
    Journal of endodontics, 2012, Volume: 38, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Apexification; Biocompatible Materials; Calcinosis; Calcium Hydroxid

2012
Effect of preoperative interventions on outcome following liver resection in a rat model of cirrhosis.
    Journal of hepatology, 2000, Volume: 32, Issue:2

    Topics: Animals; Anti-Infective Agents; Aspartate Aminotransferases; Bilirubin; Ciprofloxacin; Diagnosis, Co

2000