ciprofloxacin has been researched along with Fibroma, Shope in 16 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of the current study was to evaluate the safety and efficacy of ciprofloxacin for the prevention of BK viremia in kidney transplant recipients." | 9.30 | Ciprofloxacin for BK viremia prophylaxis in kidney transplant recipients: Results of a prospective, double-blind, randomized, placebo-controlled trial. ( Gaber, AO; Graviss, EA; Knight, RJ; Kuten, SA; Moore, LW; Musick, WL; Nguyen, DT; Patel, SJ, 2019) |
| " Ciprofloxacin prophylaxis appears safe and effective in reducing the incidence of severe BKHC after allogeneic HSCT." | 5.37 | Efficacy and safety of ciprofloxacin for prophylaxis of polyomavirus BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients. ( Costa, LJ; Glode, A; Hogan, KR; Kramer, C; Miller, AN; Schaub, C; Stuart, RK, 2011) |
| " The purpose of the current study was to evaluate the safety and efficacy of ciprofloxacin for the prevention of BK viremia in kidney transplant recipients." | 5.30 | Ciprofloxacin for BK viremia prophylaxis in kidney transplant recipients: Results of a prospective, double-blind, randomized, placebo-controlled trial. ( Gaber, AO; Graviss, EA; Knight, RJ; Kuten, SA; Moore, LW; Musick, WL; Nguyen, DT; Patel, SJ, 2019) |
| "This analysis demonstrates for the first time that, used in a stepwise fashion, ciprofloxacin and leflunomide are effective and safe treatments for BK viremia in PRTR." | 3.80 | A novel treatment regimen for BK viremia. ( Cheam, H; Ettenger, RB; Malekzadeh, MH; Tsai, EW; Zaman, RA, 2014) |
| "Ciprofloxacin treatment reduced the viral load and improved the clinical findings." | 1.38 | BK virus nephropathy developing after renal transplantation and its treatment with ciprofloxacin: a case report. ( Bakirdoven, S; Cekmen, MB; Sayan, M; Yilmaz, A, 2012) |
| " Ciprofloxacin prophylaxis appears safe and effective in reducing the incidence of severe BKHC after allogeneic HSCT." | 1.37 | Efficacy and safety of ciprofloxacin for prophylaxis of polyomavirus BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients. ( Costa, LJ; Glode, A; Hogan, KR; Kramer, C; Miller, AN; Schaub, C; Stuart, RK, 2011) |
| "We report the first case of toxic shock syndrome that has occurred after a loop electrosurgical excision procedure." | 1.29 | Toxic shock syndrome after loop electrosurgical excision procedure. ( Greenspoon, JS; Margolin, ML; Menashe, Y; Rosen, DJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 10 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, SJ | 1 |
| Knight, RJ | 1 |
| Kuten, SA | 1 |
| Graviss, EA | 1 |
| Nguyen, DT | 1 |
| Moore, LW | 1 |
| Musick, WL | 1 |
| Gaber, AO | 1 |
| Zeidan, S | 1 |
| Esposito, L | 1 |
| Rostaing, L | 1 |
| Kamar, N | 1 |
| Zaman, RA | 1 |
| Ettenger, RB | 1 |
| Cheam, H | 1 |
| Malekzadeh, MH | 1 |
| Tsai, EW | 1 |
| Flores, V | 1 |
| Rodríguez-Sánchez, B | 1 |
| Marín-Jiménez, I | 1 |
| Bouza, E | 1 |
| Menchén, L | 1 |
| Muñoz, P | 1 |
| Halim, MA | 2 |
| Al-Otaibi, T | 2 |
| Gheith, O | 1 |
| Zkaria, Z | 1 |
| Mosaad, A | 1 |
| Said, T | 2 |
| Nair, P | 2 |
| Nampoory, N | 1 |
| Gagneux-Brunon, A | 1 |
| Pillet, S | 1 |
| Laurent, B | 1 |
| Mariat, C | 1 |
| Michalet, M | 1 |
| Lucht, F | 1 |
| Botelho-Nevers, E | 1 |
| Jun, JB | 1 |
| Choi, Y | 1 |
| Kim, H | 1 |
| Lee, SH | 1 |
| Jeong, J | 1 |
| Jung, J | 1 |
| Koukoulaki, M | 1 |
| Apostolou, T | 1 |
| Hadjiconstantinou, V | 1 |
| Drakopoulos, S | 1 |
| El-Kholy, O | 1 |
| Gheith, OA | 1 |
| Al-Waheeb, S | 1 |
| Szucs, G | 1 |
| Pacsa, A | 1 |
| Balaha, MA | 1 |
| Hasaneen, H | 1 |
| Nampoory, MR | 1 |
| Miller, AN | 1 |
| Glode, A | 1 |
| Hogan, KR | 1 |
| Schaub, C | 1 |
| Kramer, C | 1 |
| Stuart, RK | 1 |
| Costa, LJ | 1 |
| Wojciechowski, D | 1 |
| Chanda, R | 1 |
| Chandran, S | 1 |
| Lee, B | 1 |
| Webber, A | 1 |
| Macaraig, M | 1 |
| Tomlanovich, S | 1 |
| Vincenti, F | 1 |
| Cekmen, MB | 1 |
| Bakirdoven, S | 1 |
| Sayan, M | 1 |
| Yilmaz, A | 1 |
| Leung, AY | 1 |
| Chan, MT | 1 |
| Yuen, KY | 1 |
| Cheng, VC | 1 |
| Chan, KH | 1 |
| Wong, CL | 1 |
| Liang, R | 1 |
| Lie, AK | 1 |
| Kwong, YL | 1 |
| Randhawa, PS | 1 |
| Thamboo, TP | 1 |
| Jeffery, KJ | 1 |
| Friend, PJ | 1 |
| Turner, GD | 1 |
| Roberts, IS | 1 |
| Rosen, DJ | 1 |
| Margolin, ML | 1 |
| Menashe, Y | 1 |
| Greenspoon, JS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ciprofloxacin for Prevention of BK Infection in Renal Transplant Recipients[NCT01789203] | Phase 4 | 200 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| BK Viremia and BK Virus Nephropathy Post Kidney Transplant Comparison of New Practices With Traditional Approach: A Combined Retrospective Chart Review and Prospective Observational Study[NCT02758288] | 0 participants (Actual) | Observational | 2015-09-30 | Withdrawn | |||
| Effect of Fluoroquinolones on BK Viremia in the Renal Transplant Recipient, A Multi-Center Study[NCT01034176] | Phase 4 | 43 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of patients with biopsy-proven acute rejection of the allograft at 1 year, based on Banff classification (NCT01789203)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 14 |
| Placebo | 7 |
Proportion of patients developing BK viremia at 1 year (NCT01789203)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 31 |
| Placebo | 8 |
Clostridium difficile infection at 6 months (NCT01789203)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 1 |
| Placebo | 0 |
Patient death at 1 year (NCT01789203)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 1 |
| Placebo | 1 |
First BK plasma viral loads (NCT01789203)
Timeframe: 12 months
| Intervention | copies/mL (Median) |
|---|---|
| Ciprofloxacin | 2514 |
| Placebo | 1423 |
kidney failure within first 1 year of transplant (NCT01789203)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 14 |
| Placebo | 7 |
Number of patients (followed by proportion) developing BK infection at 6 months post-transplant. BK infection is defined as the presence of a detectable BK viral load in plasma by polymerase chain reaction (PCR), or the presence of BK viral inclusions on kidney biopsy specimens. (NCT01789203)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 25 |
| Placebo | 5 |
Number of patients with bacteremic infection at 6 months. Bacteremia defined by a single positive blood culture that was not thought to be contaminated. (NCT01789203)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 3 |
| Placebo | 2 |
Number of patients with gram negative urinary tract infections as defined by a midstream urine sample containing 10^4 or more colony-forming units per mL (NCT01789203)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 17 |
| Placebo | 14 |
Number of patients with quinolone-resistant gram negative bacterial infections, among those with a gram-negative infection (NCT01789203)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 15 |
| Placebo | 7 |
Serious adverse events collected for up to 4 months (3 months on study drug plus 1 additional month) (NCT01789203)
Timeframe: 4 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Ciprofloxacin | 35 |
| Placebo | 18 |
Median time to initial BK viremia episode, days (NCT01789203)
Timeframe: 12 months
| Intervention | days (Median) |
|---|---|
| Ciprofloxacin | 90 |
| Placebo | 76.5 |
Number of patients with >50% reduction in BK viral load at 6 months (NCT01034176)
Timeframe: Baseline and 6 months
| Intervention | participants (Number) |
|---|---|
| Levofloxacin | 15 |
| Placebo | 13 |
Percent change in BK virus copies/mL from Baseline to 3 months (NCT01034176)
Timeframe: Baseline and 3 months
| Intervention | Percent change of BK virus copies (Median) |
|---|---|
| Levofloxacin | 70.3 |
| Placebo | 69.1 |
2 trials available for ciprofloxacin and Fibroma, Shope
| Article | Year |
|---|---|
Ciprofloxacin for BK viremia prophylaxis in kidney transplant recipients: Results of a prospective, double-blind, randomized, placebo-controlled trial.
Topics: Adult; BK Virus; Ciprofloxacin; Double-Blind Method; Female; Fluoroquinolones; Humans; Immunosuppres | 2019 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; BK Virus; Ciprofloxacin; Female; H | 2005 |
14 other studies available for ciprofloxacin and Fibroma, Shope
| Article | Year |
|---|---|
The Achilles tendon of preventing BK virus nephropathy.
Topics: Achilles Tendon; Anti-Bacterial Agents; BK Virus; Ciprofloxacin; Humans; Kidney Diseases; Kidney Tra | 2013 |
A novel treatment regimen for BK viremia.
Topics: Adolescent; BK Virus; Child; Ciprofloxacin; Female; Fluoroquinolones; Glomerular Filtration Rate; Hu | 2014 |
Prospective study of BK virus infection in patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Age Factors; Aged; BK Virus; Case-Control Studies; Ciprofloxacin; Female; Humans; | 2014 |
Active management versus minimization of immunosuppressives of BK virus-associated nephropathy after a kidney transplant.
Topics: Adult; Antiviral Agents; Biopsy; BK Virus; Ciprofloxacin; Drug Substitution; Drug Therapy, Combinati | 2014 |
A case of BK virus nephropathy in a stem cell transplant recipient: a rare or under-recognized cause for Acute Kidney injury.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; BK Virus; Ciprofloxacin; Cord Blood Stem Cell Transplant | 2015 |
BK polyomavirus encephalitis in a patient with thrombotic microangiopathy after an allogeneic hematopoietic stem cell transplant.
Topics: Anemia, Hemolytic; Anti-Bacterial Agents; Antiviral Agents; BK Virus; Cidofovir; Ciprofloxacin; Cyst | 2016 |
Impact of prophylactic administration of ciprofloxacin on BK polyoma virus replication.
Topics: Adult; Aged; Antiviral Agents; BK Virus; Ciprofloxacin; DNA, Viral; Drug Administration Schedule; Fe | 2008 |
Active management of post-renal transplantation BK virus nephropathy: preliminary report.
Topics: Adult; Anti-Infective Agents; Biopsy; BK Virus; Ciprofloxacin; Creatinine; Female; Histocompatibilit | 2009 |
Efficacy and safety of ciprofloxacin for prophylaxis of polyomavirus BK virus-associated hemorrhagic cystitis in allogeneic hematopoietic stem cell transplantation recipients.
Topics: Adult; Aged; Anti-Infective Agents; BK Virus; Ciprofloxacin; Cystitis; Female; Hematologic Neoplasms | 2011 |
Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year.
Topics: Adult; Aged; Anti-Infective Agents; BK Virus; Chi-Square Distribution; Ciprofloxacin; Drug Administr | 2012 |
BK virus nephropathy developing after renal transplantation and its treatment with ciprofloxacin: a case report.
Topics: Antiviral Agents; BK Virus; Ciprofloxacin; Humans; Kidney Diseases; Kidney Transplantation; Male; Po | 2012 |
Anti-BK virus activity of ciprofloxacin and related antibiotics.
Topics: Anti-Infective Agents; BK Virus; Ciprofloxacin; Humans; Polyomavirus Infections; Tumor Virus Infecti | 2005 |
Anti-BK virus activity of ciprofloxacin and related antibiotics.
Topics: Anti-Infective Agents; BK Virus; Ciprofloxacin; Humans; Polyomavirus Infections; Tumor Virus Infecti | 2005 |
Anti-BK virus activity of ciprofloxacin and related antibiotics.
Topics: Anti-Infective Agents; BK Virus; Ciprofloxacin; Humans; Polyomavirus Infections; Tumor Virus Infecti | 2005 |
Anti-BK virus activity of ciprofloxacin and related antibiotics.
Topics: Anti-Infective Agents; BK Virus; Ciprofloxacin; Humans; Polyomavirus Infections; Tumor Virus Infecti | 2005 |
Urine cytology screening for polyoma virus infection following renal transplantation: the Oxford experience.
Topics: Anti-Infective Agents; Ciprofloxacin; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney Tra | 2007 |
Toxic shock syndrome after loop electrosurgical excision procedure.
Topics: Adult; Ciprofloxacin; Electrosurgery; Female; Humans; Papillomaviridae; Postoperative Complications; | 1993 |