Page last updated: 2024-10-25

ciprofloxacin and Febrile Neutropenia

ciprofloxacin has been researched along with Febrile Neutropenia in 12 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Febrile Neutropenia: Fever accompanied by a significant reduction in the number of NEUTROPHILS.

Research Excerpts

ExcerptRelevanceReference
"A phase III randomized, controlled, clinical trial, open-label parallel-group with a 1:1 ratio, aimed to demonstrate the non-inferiority of oral fosfomycin versus oral ciprofloxacin for febrile neutropenia prevention in patients with acute leukemia (AL) or hematopoietic cell transplant (HSC) receptors."9.69FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients-efficacy and microbiologic safety. ( Amigo, ML; Bernal, T; Blanco, LS; Boluda, B; Burgués, JMB; Calabuig, ML; Casas, MC; de Miguel, MI; de Ugarriza, PL; Del Mar García-Saiz, M; Domínguez, JF; Hernández, SC; Huerta, AJG; Humala, K; Lavín-Alconero, L; Moreno, AF; Verdugo, AF; Zarzuela, MP, 2023)
"Early-stage breast cancer patients receiving TC chemotherapy were randomised to either ciprofloxacin or G-CSF."9.30Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC). ( Clemons, M; Fergusson, D; Hilton, J; Hutton, B; Ibrahim, MF; Joy, A; Kehoe, A; Mallick, R; Mazzarello, S; Price-Hiller, J; Sienkiewicz, M; Stober, C; Vandermeer, L; Verma, S; Zhu, X, 2019)
"The purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis."8.31Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis ( Alıcı, N; Kaya, Z; Kırkız, S; Koçak, Ü, 2023)
" We compared the incidence of bacterial-related complications among 356 patients with multiple myeloma (MM) (n = 202) and lymphoma (n = 154) who underwent AHCT with (n = 177) or without (n = 179) ciprofloxacin prophylaxis between 03/2007 and 10/2012 and between 10/2012 and 07/2016, respectively, at a single centre."7.88Antibacterial prophylaxis with ciprofloxacin for patients with multiple myeloma and lymphoma undergoing autologous haematopoietic cell transplantation: a quasi-experimental single-centre before-after study. ( Bishara, J; Gurion, R; Herscovici, C; Lahav, M; Magen, H; Moshe, M; Naparstek, E; Pasvolsky, O; Peck, A; Raanani, P; Rozovski, U; Sela-Navon, M; Shargian, L; Vaxman, I; Vidal, L; Wolach, O; Yahav, D; Yeshurun, M, 2018)
"A phase III randomized, controlled, clinical trial, open-label parallel-group with a 1:1 ratio, aimed to demonstrate the non-inferiority of oral fosfomycin versus oral ciprofloxacin for febrile neutropenia prevention in patients with acute leukemia (AL) or hematopoietic cell transplant (HSC) receptors."5.69FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients-efficacy and microbiologic safety. ( Amigo, ML; Bernal, T; Blanco, LS; Boluda, B; Burgués, JMB; Calabuig, ML; Casas, MC; de Miguel, MI; de Ugarriza, PL; Del Mar García-Saiz, M; Domínguez, JF; Hernández, SC; Huerta, AJG; Humala, K; Lavín-Alconero, L; Moreno, AF; Verdugo, AF; Zarzuela, MP, 2023)
"Early-stage breast cancer patients receiving TC chemotherapy were randomised to either ciprofloxacin or G-CSF."5.30Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC). ( Clemons, M; Fergusson, D; Hilton, J; Hutton, B; Ibrahim, MF; Joy, A; Kehoe, A; Mallick, R; Mazzarello, S; Price-Hiller, J; Sienkiewicz, M; Stober, C; Vandermeer, L; Verma, S; Zhu, X, 2019)
"The purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis."4.31Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis ( Alıcı, N; Kaya, Z; Kırkız, S; Koçak, Ü, 2023)
" We compared the incidence of bacterial-related complications among 356 patients with multiple myeloma (MM) (n = 202) and lymphoma (n = 154) who underwent AHCT with (n = 177) or without (n = 179) ciprofloxacin prophylaxis between 03/2007 and 10/2012 and between 10/2012 and 07/2016, respectively, at a single centre."3.88Antibacterial prophylaxis with ciprofloxacin for patients with multiple myeloma and lymphoma undergoing autologous haematopoietic cell transplantation: a quasi-experimental single-centre before-after study. ( Bishara, J; Gurion, R; Herscovici, C; Lahav, M; Magen, H; Moshe, M; Naparstek, E; Pasvolsky, O; Peck, A; Raanani, P; Rozovski, U; Sela-Navon, M; Shargian, L; Vaxman, I; Vidal, L; Wolach, O; Yahav, D; Yeshurun, M, 2018)
"Febrile neutropenia: is ambulatory care possible ? Outpatient treatment of neutropenic fever post chemotherapy is possible for patients at low risk of complications."1.46[Febrile neutropenia: is ambulatory care possible]? ( Lafaurie, M, 2017)
"One patient developed Fusarium infection."1.40Bloodstream and central line isolates from hematopoietic stem cell transplant recipients: data from a developing country. ( Adil, SN; Ali, N; Shaikh, MU, 2014)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (66.67)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Yeh, TC1
Hou, JY1
Huang, TH1
Lu, CH1
Sun, FJ1
Huang, HM1
Liu, HC1
Kaya, Z1
Alıcı, N1
Kırkız, S1
Koçak, Ü1
Moreno, AF1
Lavín-Alconero, L1
de Ugarriza, PL1
Blanco, LS1
Hernández, SC1
Burgués, JMB1
de Miguel, MI1
Huerta, AJG1
Zarzuela, MP1
Boluda, B1
Humala, K1
Calabuig, ML1
Amigo, ML1
Casas, MC1
Del Mar García-Saiz, M1
Verdugo, AF1
Domínguez, JF1
Bernal, T1
Oliver, AC1
Riva, E1
Mosquera, R1
Galeano, S1
Pierri, S1
Bello, L1
Caneiro, A1
Gai, R1
Miller, A1
Muxi, P1
Conn, JR1
Catchpoole, EM1
Runnegar, N1
Mapp, SJ1
Markey, KA1
Goodlet, KJ1
Nicolau, DP1
Nailor, MD1
Yeshurun, M1
Vaxman, I1
Shargian, L1
Yahav, D1
Bishara, J1
Pasvolsky, O1
Wolach, O1
Lahav, M1
Gurion, R1
Magen, H1
Vidal, L1
Herscovici, C1
Peck, A1
Moshe, M1
Sela-Navon, M1
Naparstek, E1
Raanani, P1
Rozovski, U1
Clemons, M1
Mazzarello, S1
Hilton, J1
Joy, A1
Price-Hiller, J1
Zhu, X1
Verma, S1
Kehoe, A1
Ibrahim, MF1
Sienkiewicz, M1
Stober, C1
Vandermeer, L1
Hutton, B1
Mallick, R1
Fergusson, D1
Lafaurie, M1
Ali, N1
Adil, SN1
Shaikh, MU1
Borget, I1
Antoun, S1
Chachaty, E1
Gachot, B1
Alibay, A1
Di Palma, M1
Merad, M1
Hallböök, H1
Lidström, AK1
Pauksens, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility of Using an Integrated Consent Model to Compare Two Standard of Care Regimens for Primary Prophylaxis of Taxotere/Cyclophosphamide-Induces Febrile Neutropenia[NCT02173262]Phase 4142 participants (Actual)Interventional2014-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for ciprofloxacin and Febrile Neutropenia

ArticleYear
FOVOCIP study: a multicenter randomized trial of fosfomycin versus ciprofloxacin for febrile neutropenia in hematologic patients-efficacy and microbiologic safety.
    Trials, 2023, Oct-27, Volume: 24, Issue:1

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Febrile Neutropenia; Fosfomycin; Hematopoietic Stem Cell Trans

2023
Low rates of antibiotic resistance and infectious mortality in a cohort of high-risk hematology patients: A single center, retrospective analysis of blood stream infection.
    PloS one, 2017, Volume: 12, Issue:5

    Topics: Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Drug Resistance, Bacterial; Febrile Neutropenia; F

2017
Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC).
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:4

    Topics: Adult; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cip

2019

Other Studies

9 other studies available for ciprofloxacin and Febrile Neutropenia

ArticleYear
Effectiveness and antimicrobial susceptibility profiles during primary antimicrobial prophylaxis for pediatric acute myeloid leukemia.
    Scientific reports, 2021, 10-27, Volume: 11, Issue:1

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Antifungal Agents; Bacteremia; Child; Ciprofloxacin;

2021
Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2023, 08-31, Volume: 40, Issue:3

    Topics: Child; Ciprofloxacin; Febrile Neutropenia; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphobl

2023
Comparison of two different anti-infectious approaches after high-dose chemotherapy and autologous stem cell transplantation for hematologic malignancies in a 12-year period in British Hospital, Uruguay.
    Annals of hematology, 2020, Volume: 99, Issue:4

    Topics: Adolescent; Adult; Aged; Amikacin; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Prot

2020
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:12

    Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug

2017
Antibacterial prophylaxis with ciprofloxacin for patients with multiple myeloma and lymphoma undergoing autologous haematopoietic cell transplantation: a quasi-experimental single-centre before-after study.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2018, Volume: 24, Issue:7

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Ciprofloxacin; Controlled Be

2018
[Febrile neutropenia: is ambulatory care possible]?
    La Revue du praticien, 2017, Volume: 67, Issue:2

    Topics: Administration, Oral; Ambulatory Care; Anti-Bacterial Agents; Ciprofloxacin; Febrile Neutropenia; Hu

2017
Bloodstream and central line isolates from hematopoietic stem cell transplant recipients: data from a developing country.
    Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:1

    Topics: Acyclovir; Adolescent; Adult; Anti-Infective Agents; Bacteremia; Candida albicans; Candidiasis; Cath

2014
[Modalities of management of cancer patients with febrile neutropenia in the oncology emergency unit of Gustave-Roussy and their related costs].
    Bulletin du cancer, 2014, Volume: 101, Issue:10

    Topics: Adult; Aged; Ambulatory Care; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents;

2014
Ciprofloxacin prophylaxis delays initiation of broad-spectrum antibiotic therapy and reduces the overall use of antimicrobial agents during induction therapy for acute leukaemia: A single-centre study.
    Infectious diseases (London, England), 2016, Volume: 48, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Bacterial Infections; Carbapenems

2016