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ciprofloxacin and Experimental Radiation Injuries

ciprofloxacin has been researched along with Experimental Radiation Injuries in 8 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"The effect of oral therapy with three quinolones (ofloxacin, ciprofloxacin, and pefloxacin) in the prevention of postirradiation bacteremia and mortality was tested in B6D2F1 mice given 9."3.68Quinolone therapy in the prevention of mortality after irradiation. ( Brook, I; Elliott, TB, 1991)
"Ionizing radiation exposure combined with wound injury increases animal mortalities than ionizing radiation exposure alone."1.42Ciprofloxacin Therapy Results in Mitigation of ATP Loss after Irradiation Combined with Wound Trauma: Preservation of Pyruvate Dehydrogenase and Inhibition of Pyruvate Dehydrogenase Kinase 1. ( Kiang, JG; Smith, JT; Swift, JM, 2015)
"Severe hematopoietic loss is one of the major therapeutic targets after radiation-combined injury (CI), a kind of injury resulting from radiation exposure combined with other traumas."1.40Ciprofloxacin enhances stress erythropoiesis in spleen and increases survival after whole-body irradiation combined with skin-wound trauma. ( Burns, TM; Fukumoto, R; Kiang, JG, 2014)
"Radiation combined injury (CI) is a radiation injury (RI) combined with other types of injury, which generally leads to greater mortality than RI alone."1.39Ciprofloxacin modulates cytokine/chemokine profile in serum, improves bone marrow repopulation, and limits apoptosis and autophagy in ileum after whole body ionizing irradiation combined with skin-wound trauma. ( Cary, LH; Elliott, TB; Fukumoto, R; Gorbunov, NV; Kiang, JG; Lombardini, ED, 2013)
"Ciprofloxacin-treated animals had higher survival compared with clindamycin-treated animals in two experiments, and less survival in a third experiment, although differences were not statistically significant."1.33Clindamycin and quinolone therapy for Bacillus anthracis Sterne infection in 60Co-gamma-photon-irradiated and sham-irradiated mice. ( Bolduc, DL; Brook, I; Camp-Hyde, TD; Elliott, TB; Foriska, MA; Germana, A; Giraldo, DE; Jackson, WE; Ledney, GD; Shoemaker, MO; Thakar, JH, 2005)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukumoto, R3
Cary, LH1
Gorbunov, NV1
Lombardini, ED1
Elliott, TB4
Kiang, JG4
Burns, TM1
Swift, JM1
Smith, JT1
Brook, I3
Germana, A1
Giraldo, DE1
Camp-Hyde, TD1
Bolduc, DL1
Foriska, MA1
Thakar, JH1
Shoemaker, MO1
Jackson, WE1
Ledney, GD2
Romanchuk, LA1
Bush, V1
Korshunov, VM1

Other Studies

8 other studies available for ciprofloxacin and Experimental Radiation Injuries

ArticleYear
Ciprofloxacin modulates cytokine/chemokine profile in serum, improves bone marrow repopulation, and limits apoptosis and autophagy in ileum after whole body ionizing irradiation combined with skin-wound trauma.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Anti-Infective Agents; Apoptosis; Autophagy; Bacterial Infections; Ciprofloxacin; Cytokines

2013
Ciprofloxacin enhances stress erythropoiesis in spleen and increases survival after whole-body irradiation combined with skin-wound trauma.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Anemia; Animals; Bone Morphogenetic Protein 4; Ciprofloxacin; Erythropoiesis; Erythropoietin; Female

2014
Ciprofloxacin increases survival after ionizing irradiation combined injury: γ-H2AX formation, cytokine/chemokine, and red blood cells.
    Health physics, 2014, Volume: 106, Issue:6

    Topics: Animals; Bone Marrow Cells; Chemokines; Ciprofloxacin; Erythrocyte Count; Female; Histones; Mice; Ra

2014
Ciprofloxacin Therapy Results in Mitigation of ATP Loss after Irradiation Combined with Wound Trauma: Preservation of Pyruvate Dehydrogenase and Inhibition of Pyruvate Dehydrogenase Kinase 1.
    Radiation research, 2015, Volume: 183, Issue:6

    Topics: Adenosine Triphosphate; Administration, Oral; Animals; Ciprofloxacin; Female; Gamma Rays; HSP70 Heat

2015
Clindamycin and quinolone therapy for Bacillus anthracis Sterne infection in 60Co-gamma-photon-irradiated and sham-irradiated mice.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 56, Issue:6

    Topics: Administration, Oral; Animals; Anthrax; Anti-Bacterial Agents; Aza Compounds; Bacillus anthracis; Bl

2005
[Selective decontamination of the intestine and total gnotobiologic isolation in treatment of mice with acute radiation sickness].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1992, Volume: 37, Issue:1

    Topics: Acute Disease; Amikacin; Animals; Ciprofloxacin; Decontamination; Germ-Free Life; Intestines; Mice;

1992
Quinolone therapy in the prevention of mortality after irradiation.
    Radiation research, 1991, Volume: 128, Issue:1

    Topics: Animals; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Cobalt Radioisotopes; Female; Gamma Rays;

1991
Quinolone therapy of Klebsiella pneumoniae sepsis following irradiation: comparison of pefloxacin, ciprofloxacin, and ofloxacin.
    Radiation research, 1990, Volume: 122, Issue:2

    Topics: Animals; Ciprofloxacin; Female; Klebsiella Infections; Klebsiella pneumoniae; Mice; Ofloxacin; Peflo

1990