ciprofloxacin has been researched along with Eardrum Perforation in 14 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical ciprofloxacin and dexamethasone have both been shown to disrupt healing of tympanic membrane perforations in animal models." | 4.02 | The Influence of Ciprofloxacin-Dexamethasone Ear Drops on Perforation Closure Rates After Endoscopic Tympanoplasty. ( James, AL; Sharma, SD, 2021) |
| "Objective Ciprofloxacin + dexamethasone ear drops have been associated with higher rates of tympanic membrane perforations than ofloxacin." | 3.88 | Effects of Common Ear Drops on Tympanic Membrane Healing in Rats. ( Antonelli, PJ; Dirain, CO; Kosko, B, 2018) |
| " Local tolerance of topically-administered ciprofloxacin (ear drops) and serum antibiotic levels after 7-10 days of treatment were evaluated in 30 children with tympanic membrane perforation and suppuration." | 3.70 | [Determination of plasma ciprofloxacin levels in children treated with 0.2% topical ciprofloxacin for tympanic perforation]. ( Clarós, A; Clarós, P; Sabater, F, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Dirain, CO | 2 |
| Karnani, DN | 1 |
| Antonelli, PJ | 3 |
| Ahmed, MN | 1 |
| Shetty, P | 1 |
| Saunders, N | 1 |
| Bhutta, MF | 1 |
| Sharma, SD | 1 |
| James, AL | 1 |
| Kosko, B | 1 |
| Gupta, M | 1 |
| Singh, S | 1 |
| Singh, H | 1 |
| Chauhan, B | 1 |
| Maerz, DA | 1 |
| Gainsburg, DM | 1 |
| Vaile, L | 2 |
| Williamson, T | 2 |
| Waddell, A | 2 |
| Taylor, GJ | 1 |
| Winterstein, AG | 1 |
| Schultz, GS | 1 |
| Jaya, C | 1 |
| Job, A | 1 |
| Mathai, E | 1 |
| Antonisamy, B | 1 |
| Dugdale, AE | 1 |
| Taylor, G | 1 |
| Buyten, J | 1 |
| Kaufman, G | 1 |
| Ryan, M | 1 |
| Kasemsuwan, L | 1 |
| Clongsuesuek, P | 1 |
| Clarós, P | 1 |
| Sabater, F | 1 |
| Clarós, A | 2 |
2 reviews available for ciprofloxacin and Eardrum Perforation
| Article | Year |
|---|---|
WITHDRAWN: Interventions for ear discharge associated with grommets (ventilation tubes).
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cerebrospinal Fluid Oto | 2016 |
Interventions for ear discharge associated with grommets (ventilation tubes).
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cerebrospinal Fluid Oto | 2006 |
3 trials available for ciprofloxacin and Eardrum Perforation
| Article | Year |
|---|---|
To study the role of antibiotic+steroid irrigation of the middle ear in active chronic otitis media with small perforation and pulsatile discharge.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Ceftriaxone; Ciprofloxacin; Dexamethasone; Follow-Up | 2014 |
Evaluation of topical povidone-iodine in chronic suppurative otitis media.
Topics: Administration, Topical; Adolescent; Adult; Anti-Infective Agents, Local; Child; Chronic Disease; Ci | 2003 |
A double blind, prospective trial of topical ciprofloxacin versus normal saline solution in the treatment of otorrhoea.
Topics: Administration, Topical; Adult; Aged; Anti-Infective Agents; Bacteria, Aerobic; Cerebrospinal Fluid | 1997 |
9 other studies available for ciprofloxacin and Eardrum Perforation
| Article | Year |
|---|---|
Commercial Quinolone Ear Drops Cause Perforations in Intact Rat Tympanic Membranes.
Topics: Animals; Ciprofloxacin; Dexamethasone; Female; Hydrocortisone; Male; Methylprednisolone Hemisuccinat | 2019 |
Permanent Facial Paralysis and Hearing Loss After Aural Irrigation.
Topics: Aged; Anti-Bacterial Agents; Cerumen; Ciprofloxacin; Facial Paralysis; Female; Hearing Loss, Mixed C | 2020 |
The Influence of Ciprofloxacin-Dexamethasone Ear Drops on Perforation Closure Rates After Endoscopic Tympanoplasty.
Topics: Administration, Topical; Adolescent; Child; Child, Preschool; Ciprofloxacin; Dexamethasone; Humans; | 2021 |
Effects of Common Ear Drops on Tympanic Membrane Healing in Rats.
Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Dexamethasone; Glucocorticoids; Instillation, Drug; M | 2018 |
Tympanic membrane rupture during robotic-assisted laparoscopic prostatectomy.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Dexamethasone; Head-Down Tilt; Human | 2016 |
Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study.
Topics: Administration, Cutaneous; Animals; Anti-Infective Agents; Chi-Square Distribution; Chinchilla; Cipr | 2010 |
Management of chronic suppurative otitis media.
Topics: Administration, Topical; Anti-Infective Agents; Child; Child, Preschool; Chronic Disease; Ciprofloxa | 2004 |
Effects of ciprofloxacin/dexamethasone and ofloxacin on tympanic membrane perforation healing.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Dexamethasone; Ofloxacin; R | 2007 |
[Determination of plasma ciprofloxacin levels in children treated with 0.2% topical ciprofloxacin for tympanic perforation].
Topics: Administration, Topical; Anti-Infective Agents; Child; Child, Preschool; Ciprofloxacin; Ear Diseases | 2000 |