ciprofloxacin has been researched along with Earache in 6 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Earache: Pain in the ear.
| Excerpt | Relevance | Reference |
|---|---|---|
| "025%, otic solution seems to be efficacious and safe in treating acute otitis externa (AOE) compared with ciprofloxacin, 0." | 7.11 | Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Among Patients With Acute Otitis Externa: A Randomized Clinical Trial. ( Aazami, H; Acosta, AM; Ansley, JF; Chu, L; De Valle, O; Dennis, P; Ehmer, D; Hedrick, JA, 2022) |
| "In the light of current concerns regarding ciprofloxacin resistance and the changing face of malignant otitis externa, we reviewed cases of malignant otitis externa treated in our centre, in order both to evaluate the current epidemiology of the condition and to assess the status of drug resistance in our patient population." | 3.76 | Malignant otitis externa: case series. ( Ali, T; Anari, S; ElBadawey, MR; Meade, K; Zammit-Maempel, I, 2010) |
| "025%, otic solution seems to be efficacious and safe in treating acute otitis externa (AOE) compared with ciprofloxacin, 0." | 3.11 | Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Among Patients With Acute Otitis Externa: A Randomized Clinical Trial. ( Aazami, H; Acosta, AM; Ansley, JF; Chu, L; De Valle, O; Dennis, P; Ehmer, D; Hedrick, JA, 2022) |
| " Eight adverse effects were observed in five patients and treatment had to be discontinued in one case." | 2.67 | Study of the efficacy and safety of ciprofloxacin in the treatment of chronic otitis. ( Barrault, S; Dobler, S; Ebbo, D; Fombeur, JP; Koubbi, G; Laurier, JN; Lecomte, F; Sorrel, N, 1994) |
| "Twenty patients were identified." | 1.39 | Skull base osteomyelitis: current microbiology and management. ( Neeff, M; Spielmann, PM; Yu, R, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chu, L | 1 |
| Acosta, AM | 1 |
| Aazami, H | 1 |
| Dennis, P | 1 |
| De Valle, O | 1 |
| Ehmer, D | 1 |
| Hedrick, JA | 1 |
| Ansley, JF | 1 |
| Honnurappa, V | 1 |
| Ramdass, S | 1 |
| Mahajan, N | 1 |
| Vijayendra, VK | 1 |
| Redleaf, M | 1 |
| Orioli, L | 1 |
| Boute, C | 1 |
| Eloy, P | 1 |
| De Wispelaere, JF | 1 |
| De Coene, B | 1 |
| Huang, TD | 1 |
| Ausselet, N | 1 |
| Delaere, B | 1 |
| Ali, T | 1 |
| Meade, K | 1 |
| Anari, S | 1 |
| ElBadawey, MR | 1 |
| Zammit-Maempel, I | 1 |
| Spielmann, PM | 1 |
| Yu, R | 1 |
| Neeff, M | 1 |
| Fombeur, JP | 1 |
| Barrault, S | 1 |
| Koubbi, G | 1 |
| Laurier, JN | 1 |
| Ebbo, D | 1 |
| Lecomte, F | 1 |
| Sorrel, N | 1 |
| Dobler, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase III, Multicenter, Randomized, Double-Blind Clinical Trial to Assess the Efficacy and Safety of DF289 Plus DF277 Otic Solution Compared to DF289 Otic Solution and to DF277 Otic Solution in the Treatment of Acute Otitis Externa (AOE)[NCT03196973] | Phase 3 | 493 participants (Actual) | Interventional | 2017-07-22 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Therapeutic cure will be considered achieved if edema, otalgia and otorrhea are resolved with no further requirement of antimicrobial therapy and bacteriological response is Eradication or Presumed Eradication (NCT03196973)
Timeframe: End of Treatment (Day 8+2)
| Intervention | Participants (Count of Participants) |
|---|---|
| DF289 Plus DF277 | 63 |
| DF289 | 49 |
| DF277 | 20 |
First day on which there is no use of analgesics, the pain score is zero and remains zero until end of study (NCT03196973)
Timeframe: From baseline to End of Study (Day 15+2)
| Intervention | days (Median) |
|---|---|
| DF289 Plus DF277 | 5.0 |
| DF289 | 5.9 |
| DF277 | 7.7 |
2 trials available for ciprofloxacin and Earache
| Article | Year |
|---|---|
Efficacy and Safety of Ciprofloxacin Plus Fluocinolone Acetonide Among Patients With Acute Otitis Externa: A Randomized Clinical Trial.
Topics: Acute Disease; Administration, Topical; Adult; Anti-Bacterial Agents; Ciprofloxacin; Earache; Female | 2022 |
Study of the efficacy and safety of ciprofloxacin in the treatment of chronic otitis.
Topics: Adult; Bacterial Infections; Chronic Disease; Ciprofloxacin; Earache; Female; Humans; Male; Middle A | 1994 |
4 other studies available for ciprofloxacin and Earache
| Article | Year |
|---|---|
Effective Inexpensive Management of Necrotizing Otitis Externa Is Possible in Resource-Poor Settings.
Topics: Anti-Bacterial Agents; Ciprofloxacin; Earache; Female; Humans; India; Male; Meropenem; Middle Aged; | 2019 |
Central skull base osteomyelitis: a rare but life-threatening disease.
Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Delayed Diagnosis; Earache; Humans; Magnetic Resonance I | 2015 |
Malignant otitis externa: case series.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Cranial Nerve Diseases; Diabetes Mell | 2010 |
Skull base osteomyelitis: current microbiology and management.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Anti-Infective Agents; Aspergillosis; Ceftazidime; Cipro | 2013 |