ciprofloxacin has been researched along with Drug Hypersensitivity in 46 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare meropenem with ciprofloxacin for treatment of gram-negative bacilli sepsis in penicillin-allergic patients in the intensive care unit (ICU) to determine if increased anaphylaxis risk with meropenem precluded its use when weighed against risks of inactive therapy with ciprofloxacin." | 8.87 | Life-years gained with meropenem over ciprofloxacin in penicillin-allergic patients with gram-negative bacilli sepsis: results of a probabilistic model. ( Bolon, MK; Esterly, JS; Lee, TA; Postelnick, M; Reddy, P; Scheetz, MH, 2011) |
| "Serum sickness is a systemic hypersensitivity reaction initially reported in children receiving horse serum." | 5.28 | Serum sickness-like illness associated with ciprofloxacin. ( Slama, TG, 1990) |
| "To compare meropenem with ciprofloxacin for treatment of gram-negative bacilli sepsis in penicillin-allergic patients in the intensive care unit (ICU) to determine if increased anaphylaxis risk with meropenem precluded its use when weighed against risks of inactive therapy with ciprofloxacin." | 4.87 | Life-years gained with meropenem over ciprofloxacin in penicillin-allergic patients with gram-negative bacilli sepsis: results of a probabilistic model. ( Bolon, MK; Esterly, JS; Lee, TA; Postelnick, M; Reddy, P; Scheetz, MH, 2011) |
| "Although ciprofloxacin is a generally well-tolerated fluoroquinolone antibiotic, serious and life-threatening adverse events such as anaphylaxis and pulmonary edema have been described with its use." | 4.86 | Anaphylactoid reaction considered ciprofloxacin related: a case report and literature review. ( Fleisher, J; Kelesidis, T; Tsiodras, S, 2010) |
| " Norfloxacin has been incriminated previously as a cause once only, with acute interstitial nephritis (AIN) as the histopathological finding." | 4.79 | Allergic nephropathy associated with norfloxacin and ciprofloxacin therapy. Report of two cases and review of the literature. ( Almroth, G; Cederbrant, K; Eneström, S; Hadimeri, H; Hultman, P; Lindell, A, 1997) |
| " Additionally, multiple drug hypersensitivity in five patients (distant n = 4, sequential n = 1), among whom two patients showed hypersensitivity against ceftazidime/piperacillin-tazobactam+ ciprofloxacin/levofloxacin, two patients showed hypersensitivity against ceftazidime+ ciprofloxacin n = 2, and one patient showed hypersensitivity against piperacillin-tazobactam+ amikacin+ trimethoprim-sulfamethoxazole." | 4.12 | Antibiotic allergy in children with cystic fibrosis: A retrospective case-control study. ( Güler, N; Süleyman, A; Tamay, Z, 2022) |
| "Neuromuscular blocking agents (NMBAs) like atracurium and rocuronium as well as fluoroquinolones (FQs) cause mast cell-mediated anaphylaxis by activating Mas-related G protein-coupled receptor X2 (MRGPRX2), but many questions remain unanswered." | 4.02 | Novel Insights on MRGPRX2-Mediated Hypersensitivity to Neuromuscular Blocking Agents And Fluoroquinolones. ( Bridts, CH; Campillo-Davo, D; De Puysseleyr, LP; Ebo, DG; Elst, J; Faber, MA; Hagendorens, MM; Lion, E; Maurer, M; Mertens, C; Sabato, V; van der Poorten, MM; Van Gasse, AL; Van Houdt, M; Van Tendeloo, VF, 2021) |
| "To better understand how T cells interact with quinolones, we analysed six patients with delayed hypersensitivity reactions to ciprofloxacin (CPFX), norfloxacin (NRFX) or moxifloxacin (MXFX)." | 3.73 | T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity. ( Depta, JP; Pichler, WJ; Schmid, DA, 2006) |
| "We report a case of ciprofloxacin-related allergic tubulointerstitial nephritis, which manifested as nonoliguric renal failure, eosinophilia, and eosinophiluria." | 3.68 | Allergic nephropathy associated with ciprofloxacin. ( Atkinson, JL; McCarthy, JT; Rastogi, S, 1990) |
| "Moxifloxacin has unique side chains at positions 7 and 8 on its bicyclic ring structure." | 1.36 | Immediate hypersensitivity to moxifloxacin with tolerance to ciprofloxacin: report of three cases and review of the literature. ( Chang, B; Knowles, SR; Weber, E, 2010) |
| "Ciprofloxacin (CPFX) is a widely used fluoroquinolone antibiotic, inducing cutaneous adverse drug reactions in about 1 to 2% of the treated patients." | 1.30 | Cutaneous adverse reaction to ciprofloxacin: demonstration of specific lymphocyte proliferation and cross-reactivity to ofloxacin in vitro. ( Gleichmann, E; Hunzelmann, N; Rönnau, AC; Ruzicka, T; Sachs, B; Schuppe, HC; von Schmiedeberg, S, 1997) |
| "Seven cases of anaphylactoid reaction to ciprofloxacin have now been documented in HIV-infected patients." | 1.28 | Hypersensitivity and anaphylactoid reactions to ciprofloxacin. ( Deamer, RL; Loman, GJ; Prichard, JG, 1992) |
| "Serum sickness is a systemic hypersensitivity reaction initially reported in children receiving horse serum." | 1.28 | Serum sickness-like illness associated with ciprofloxacin. ( Slama, TG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.52) | 18.7374 |
| 1990's | 22 (47.83) | 18.2507 |
| 2000's | 8 (17.39) | 29.6817 |
| 2010's | 10 (21.74) | 24.3611 |
| 2020's | 3 (6.52) | 2.80 |
| Authors | Studies |
|---|---|
| Süleyman, A | 1 |
| Tamay, Z | 1 |
| Güler, N | 1 |
| Loli-Ausejo, D | 1 |
| Vílchez-Sánchez, F | 1 |
| Cabañas, R | 1 |
| Fiandor, A | 1 |
| Lluch-Bernal, M | 1 |
| González-Muñoz, M | 1 |
| Domínguez-Ortega, J | 1 |
| Elst, J | 1 |
| Maurer, M | 1 |
| Sabato, V | 1 |
| Faber, MA | 1 |
| Bridts, CH | 1 |
| Mertens, C | 1 |
| Van Houdt, M | 1 |
| Van Gasse, AL | 1 |
| van der Poorten, MM | 1 |
| De Puysseleyr, LP | 1 |
| Hagendorens, MM | 1 |
| Van Tendeloo, VF | 1 |
| Lion, E | 1 |
| Campillo-Davo, D | 1 |
| Ebo, DG | 1 |
| Dewart, CM | 1 |
| Gao, Y | 1 |
| Rahman, P | 1 |
| Mbodj, A | 1 |
| Hade, EM | 1 |
| Stevenson, K | 1 |
| Hebert, CL | 1 |
| Ouni, B | 1 |
| Fathallah, N | 1 |
| Slim, R | 1 |
| Brahim, A | 1 |
| Ben Salem, C | 1 |
| Roy, S | 1 |
| Gupta, K | 1 |
| Ganguly, A | 1 |
| Ali, H | 1 |
| Dubini, M | 1 |
| Marraccini, P | 1 |
| Pignatti, P | 1 |
| Ang, JY | 1 |
| Abdel-Haq, N | 1 |
| Zhu, F | 1 |
| Thabit, AK | 1 |
| Nicolau, DP | 1 |
| Satlin, MJ | 1 |
| van Duin, D | 1 |
| Kuretski, J | 1 |
| Dahya, V | 1 |
| Cason, L | 1 |
| Chalasani, P | 1 |
| Ramgopal, M | 1 |
| Steurer, J | 1 |
| Contreras Z, E | 1 |
| Zuluaga M, SX | 1 |
| Díaz M, JC | 1 |
| Vejarano J, GL | 1 |
| Loriot, Y | 1 |
| Ferte, C | 1 |
| Gomez-Roca, C | 1 |
| Moldovan, C | 1 |
| Bahleda, R | 1 |
| Wislez, M | 1 |
| Cadranel, J | 1 |
| Soria, JC | 1 |
| Chang, B | 1 |
| Knowles, SR | 1 |
| Weber, E | 1 |
| Kelesidis, T | 1 |
| Fleisher, J | 1 |
| Tsiodras, S | 1 |
| Scheetz, MH | 1 |
| Bolon, MK | 1 |
| Esterly, JS | 1 |
| Reddy, P | 1 |
| Postelnick, M | 1 |
| Lee, TA | 1 |
| Marra, F | 1 |
| Cox, VC | 1 |
| FitzGerald, JM | 1 |
| Moadebi, S | 1 |
| Elwood, RK | 1 |
| Schmid, DA | 1 |
| Depta, JP | 1 |
| Pichler, WJ | 1 |
| Park, M | 1 |
| Markus, P | 1 |
| Matesic, D | 1 |
| Li, JT | 1 |
| Isik, SR | 1 |
| Karakaya, G | 1 |
| Erkin, G | 1 |
| Kalyoncu, AF | 1 |
| Guharoy, SR | 1 |
| Dávila, I | 1 |
| Diez, ML | 1 |
| Quirce, S | 1 |
| Fraj, J | 1 |
| De La Hoz, B | 1 |
| Lazaro, M | 1 |
| Lantner, RR | 1 |
| Matsuno, K | 1 |
| Kunihiro, E | 1 |
| Yamatoya, O | 1 |
| Miyata, K | 1 |
| Hasegawa, H | 1 |
| Fujita, H | 1 |
| Yamauchi, K | 1 |
| Hirakawa, Y | 1 |
| Gea-Banacloche, JC | 1 |
| Metcalfe, DD | 1 |
| Landor, M | 1 |
| Lashinsky, A | 1 |
| Waxman, J | 1 |
| Salon, EJ | 1 |
| Newbrough, MA | 1 |
| Albarracin, CA | 1 |
| Hernandez, JE | 1 |
| Mani, V | 1 |
| Cartwright, K | 1 |
| Dooley, J | 1 |
| Swarbrick, E | 1 |
| Fairclough, P | 1 |
| Oakley, C | 1 |
| Lieu, PK | 1 |
| Tok, SC | 1 |
| Ismail, NH | 1 |
| Chng, HH | 1 |
| Reaño, M | 1 |
| Vives, R | 1 |
| Rodríguez, J | 1 |
| Daroca, P | 1 |
| Canto, G | 1 |
| Fernández, J | 1 |
| Rönnau, AC | 1 |
| Sachs, B | 1 |
| von Schmiedeberg, S | 1 |
| Hunzelmann, N | 1 |
| Ruzicka, T | 1 |
| Gleichmann, E | 1 |
| Schuppe, HC | 1 |
| Hadimeri, H | 1 |
| Almroth, G | 1 |
| Cederbrant, K | 1 |
| Eneström, S | 1 |
| Hultman, P | 1 |
| Lindell, A | 1 |
| Bircher, AJ | 1 |
| Rutishauser, M | 1 |
| Erdem, G | 1 |
| Staat, MA | 1 |
| Connelly, BL | 1 |
| Assa'ad, A | 1 |
| Burke, P | 1 |
| Burne, SR | 1 |
| Scala, E | 1 |
| Giani, M | 1 |
| Pirrotta, L | 1 |
| Guerra, EC | 1 |
| De Pità, O | 1 |
| Puddu, P | 1 |
| Deamer, RL | 1 |
| Prichard, JG | 1 |
| Loman, GJ | 1 |
| Baciewicz, AM | 1 |
| Georges, G | 1 |
| Becker, M | 1 |
| Schnall, AM | 1 |
| Bhatia, RS | 1 |
| Andersen, I | 1 |
| Sjöström, P | 1 |
| Slama, TG | 1 |
| Rastogi, S | 1 |
| Atkinson, JL | 1 |
| McCarthy, JT | 1 |
| Helmink, R | 1 |
| Benediktsson, H | 1 |
| Davis, H | 1 |
| McGoodwin, E | 1 |
| Reed, TG | 1 |
| Ying, LS | 1 |
| Johnson, CA | 1 |
| Rippelmeyer, DJ | 1 |
| Synhavsky, A | 1 |
5 reviews available for ciprofloxacin and Drug Hypersensitivity
| Article | Year |
|---|---|
Anaphylactoid reaction considered ciprofloxacin related: a case report and literature review.
Topics: Adult; Anaphylaxis; Angioedema; Anti-Infective Agents; Ciprofloxacin; Drug Hypersensitivity; Female; | 2010 |
Life-years gained with meropenem over ciprofloxacin in penicillin-allergic patients with gram-negative bacilli sepsis: results of a probabilistic model.
Topics: Anaphylaxis; Anti-Bacterial Agents; Ciprofloxacin; Decision Trees; Drug Hypersensitivity; Gram-Negat | 2011 |
Ciprofloxacin-induced cutaneous vasculitis.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Drug Hypersensitivity; Humans; Male; Vasculitis, Leukocy | 1997 |
Allergic nephropathy associated with norfloxacin and ciprofloxacin therapy. Report of two cases and review of the literature.
Topics: Aged; Anti-Infective Agents; Biopsy; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Kidney; N | 1997 |
Laryngeal edema related to ciprofloxacin therapy.
Topics: Aged; Aged, 80 and over; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Del | 1992 |
1 trial available for ciprofloxacin and Drug Hypersensitivity
| Article | Year |
|---|---|
Topics: Acute Disease; Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Ciprofloxacin; C | 2017 |
40 other studies available for ciprofloxacin and Drug Hypersensitivity
| Article | Year |
|---|---|
Antibiotic allergy in children with cystic fibrosis: A retrospective case-control study.
Topics: Amikacin; Anti-Bacterial Agents; Azithromycin; Case-Control Studies; Ceftazidime; Child; Ciprofloxac | 2022 |
Basophil activation test in the diagnosis of hypersensitivity reactions to quinolones in a real-life setting.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Basophil Degranulation Test; Ciprofloxacin; D | 2021 |
Novel Insights on MRGPRX2-Mediated Hypersensitivity to Neuromuscular Blocking Agents And Fluoroquinolones.
Topics: Anaphylaxis; Anti-Bacterial Agents; Atracurium; Calcium Signaling; Cell Degranulation; Cells, Cultur | 2021 |
Penicillin allergy and association with ciprofloxacin coverage in community-onset urinary tract infection.
Topics: Antimicrobial Stewardship; Ciprofloxacin; Community-Acquired Infections; Drug Hypersensitivity; Drug | 2018 |
Anaphylactic shock secondary to oral ofloxacin administration with cross-reactivity to levofloxacin and ciprofloxacin.
Topics: Administration, Oral; Adolescent; Anaphylaxis; Ciprofloxacin; Cross Reactions; Drug Hypersensitivity | 2018 |
β-Arrestin2 expressed in mast cells regulates ciprofloxacin-induced pseudoallergy and IgE-mediated anaphylaxis.
Topics: Anaphylaxis; Animals; beta-Arrestin 2; Ciprofloxacin; Drug Hypersensitivity; Gene Expression Regulat | 2019 |
Multiple drug allergy: A case of anaphylaxis to levofloxacin but tolerance to ciprofloxacin.
Topics: Adolescent; Amoxicillin; Anaphylaxis; Ciprofloxacin; Clarithromycin; Cross Reactions; Drug Hypersens | 2016 |
Multidrug-Resistant Pseudomonas aeruginosa Infection in a Child with Cystic Fibrosis.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Cystic Fibrosis; Drug Hype | 2016 |
Nocardia Bacteremia and Endocarditis in a Patient With a Sulfa Allergy.
Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Drug Hypersensitivity; Dyspnea; Endocard | 2016 |
[Allergic reaction to ciprofloxacin: a case report].
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Urinary Tract Infection | 2008 |
Pemetrexed-induced pneumonitis: a case report.
Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Non-Small-Ce | 2009 |
Immediate hypersensitivity to moxifloxacin with tolerance to ciprofloxacin: report of three cases and review of the literature.
Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Bronchiectasis; Ciprofloxacin; Drug Eruptions; Drug Hyp | 2010 |
Successful treatment of multidrug-resistant tuberculosis following drug-induced hepatic necrosis requiring liver transplant.
Topics: Adult; Anti-Infective Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Ciprofl | 2004 |
T cell-mediated hypersensitivity to quinolones: mechanisms and cross-reactivity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antigen-Presenting Cells; Aza Compounds; Cell | 2006 |
Safety and effectiveness of a preoperative allergy clinic in decreasing vancomycin use in patients with a history of penicillin allergy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; beta-Lact | 2006 |
Multidrug-induced erythema multiforme.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Ceftriaxone; Ci | 2007 |
Serum sickness secondary to ciprofloxacin use.
Topics: Arthralgia; Cefazolin; Ciprofloxacin; Drug Hypersensitivity; Eosinophilia-Myalgia Syndrome; Female; | 1994 |
Cross-reactivity between quinolones. Report of three cases.
Topics: Adult; Anaphylaxis; Anti-Infective Agents; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Mid | 1993 |
Ciprofloxacin desensitization in a patient with cystic fibrosis.
Topics: Administration, Oral; Adolescent; Ciprofloxacin; Cystic Fibrosis; Desensitization, Immunologic; Drug | 1995 |
Surveillance of adverse reactions due to ciprofloxacin in Japan.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Cipr | 1995 |
Ciprofloxacin desensitization.
Topics: Adult; Ciprofloxacin; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans | 1996 |
Quinolone allergy?
Topics: Biopsy; Ciprofloxacin; Dermatitis Herpetiformis; Diagnosis, Differential; Drug Eruptions; Drug Hyper | 1996 |
Anaphylactoid reaction to ciprofloxacin versus toxic shock syndrome.
Topics: Anti-Infective Agents; Ciprofloxacin; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans | 1997 |
Antibiotic prophylaxis in gastrointestinal endoscopy: a report by a Working Party for the British Society of Gastroenterology Endoscopy Committee.
Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophyla | 1997 |
Ciprofloxacin-induced vasculitis.
Topics: Administration, Oral; Anti-Infective Agents; Autoimmune Diseases; Ciprofloxacin; Diagnosis, Differen | 1997 |
Cutaneous adverse reaction to ciprofloxacin: demonstration of specific lymphocyte proliferation and cross-reactivity to ofloxacin in vitro.
Topics: Aged; Anti-Infective Agents; Ciprofloxacin; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; | 1997 |
Oral "desensitization" of maculopapular exanthema from ciprofloxacin.
Topics: Administration, Oral; Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Desensitization, Immu | 1997 |
Allergic reactions to ciprofloxacin chemoprophylaxis.
Topics: Anti-Infective Agents; Chemoprevention; Ciprofloxacin; Disease Outbreaks; Drug Hypersensitivity; Hum | 1999 |
Anaphylactic reaction to ciprofloxacin in a toddler: successful desensitization.
Topics: Anaphylaxis; Anti-Infective Agents; Child, Preschool; Ciprofloxacin; Desensitization, Immunologic; D | 1999 |
Allergy associated with ciprofloxacin.
Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Hypersensitivity | 2000 |
Multiple drug allergy syndrome: severe anaphylactic reaction due to topical rifamycin SV in a patient with hypersensitivity to ciprofloxacin.
Topics: Anaphylaxis; Anti-Bacterial Agents; Anti-Infective Agents; Antirheumatic Agents; Ciprofloxacin; Drug | 2001 |
Hypersensitivity and anaphylactoid reactions to ciprofloxacin.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Anaphylaxis; Ciprofloxacin; Drug Hy | 1992 |
Adverse reaction to ciprofloxacin.
Topics: Abscess; Adult; Ciprofloxacin; Drug Eruptions; Drug Hypersensitivity; Humans; Male; Premedication | 1991 |
[Ciprofloxacin can cause allergic interstitial nephritis with acute renal failure].
Topics: Acute Kidney Injury; Aged; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Nephritis, Intersti | 1991 |
Serum sickness-like illness associated with ciprofloxacin.
Topics: Arthritis; Bacterial Infections; Ciprofloxacin; Drug Hypersensitivity; Humans; Liver Function Tests; | 1990 |
Allergic nephropathy associated with ciprofloxacin.
Topics: Acute Kidney Injury; Aged; Ciprofloxacin; Drug Hypersensitivity; Eosinophilia; Humans; Male; Nephrit | 1990 |
Ciprofloxacin-induced allergic interstitial nephritis.
Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Drug Hypersensitivity; Drug Therapy, Combination; Humans | 1990 |
Anaphylactoid reactions reported after treatment with ciprofloxacin.
Topics: Adolescent; Adult; Anaphylaxis; Child; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Male; M | 1989 |
Ciprofloxacin-induced interstitial nephritis.
Topics: Adult; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Klebsiella Infections; Klebsiella pneum | 1989 |
Ciprofloxacin and allergic interstitial nephritis.
Topics: Acute Kidney Injury; Ciprofloxacin; Drug Hypersensitivity; Female; Humans; Middle Aged; Nephritis, I | 1988 |