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ciprofloxacin and Dermatitis, Contact, Phototoxic

ciprofloxacin has been researched along with Dermatitis, Contact, Phototoxic in 15 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"The incidence of phototoxicity as a side effect of ciprofloxacin appears to be increased in patients with cystic fibrosis compared to the general population (approximately 2."7.78Ciprofloxacin-induced phototoxicity in an adult cystic fibrosis population. ( Boyle, J; Elborn, JS; Hall, V; McKenna, KE; Murphy, BP; Tolland, JP, 2012)
"The incidence of phototoxicity as a side effect of ciprofloxacin appears to be increased in patients with cystic fibrosis compared to the general population (approximately 2."3.78Ciprofloxacin-induced phototoxicity in an adult cystic fibrosis population. ( Boyle, J; Elborn, JS; Hall, V; McKenna, KE; Murphy, BP; Tolland, JP, 2012)
" Vitamin C, probably due to its strong antioxidant properties, could improve and partially counteract the toxic effect of UV-A on oxidative stress parameters and prevent the damage in rat's brain tissues."1.56The possible neurobehavioral protective effects of natural antioxidant against phototoxicity attenuation of antimicrobial quinolone group in rats. ( Mansour, HA; Masoud, MA; Sheded, MS; Yahia, R, 2020)
"Liposomes are vesicular preparations that improve bioavailability of many pharmaceuticals, used even in ocular therapy."1.51Multi- and unilamellar liposomal encapsulation of ciprofloxacin as ways to modify its phototoxicity and photodegradation. ( Giebułtowicz, J; Gubernator, J; Nałęcz-Jawecki, G; Podbielska, M; Sommer, S; Zaremba-Czogalla, M; Zgadzaj, A, 2019)
" Vesicle formation observed from 48 hr after irradiation was considered similar to bullous eruptions, a known side effect of fluoroquinolones in humans."1.39A dermal phototoxicity study following intravenous infusion administration of ciprofloxacin hydrochloride in the novel microminipigs. ( Izumi, H; Kawaguchi, H; Miura, N; Miyoshi, N; Takahashi, Y; Tanimoto, A; Utsunomiya, S; Yoshikawa, T, 2013)
"In vitro, phototoxicity for cultured cells of PZFX, which is active principle of PZFX mesilate, was studied, and stability for long-wavelength ultraviolet (UVA) was examined."1.31[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies]. ( Hayakawa, H; Kawamura, Y; Miyazaki, M; Nagasawa, M; Nakamura, S; Nojima, Y, 2002)
"To elucidate the mechanism of phototoxicity induced as a side effect by some of the new quinolone antibiotics, we studied sparfloxacin (SPFX), lomefloxacin, enoxacin, ofloxacin, and ciprofloxacin."1.30Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents. ( Arakane, K; Hirobe, M; Mashiko, S; Nagano, T; Ryu, A; Umezawa, N, 1997)
"Lomefloxacin was the strongest sensitizer, followed by fleroxacin and ciprofloxacin."1.30In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation. ( Gomi, H; Hatanaka, K; Kawada, A; Matsuo, I, 1999)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (40.00)18.2507
2000's2 (13.33)29.6817
2010's6 (40.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Sanchez, JP1
Gogliotti, RD1
Domagala, JM1
Gracheck, SJ1
Huband, MD1
Sesnie, JA1
Cohen, MA1
Shapiro, MA1
Yahia, R1
Masoud, MA1
Sheded, MS1
Mansour, HA1
Zgadzaj, A1
Giebułtowicz, J1
Gubernator, J1
Podbielska, M1
Sommer, S1
Zaremba-Czogalla, M1
Nałęcz-Jawecki, G1
Moghaddam, S1
Connolly, D1
Mealey, KL1
Dassanayake, S1
Burke, NS1
Beberok, A1
Wrześniok, D1
Rzepka, Z1
Rok, J1
Delijewski, M1
Otręba, M1
Respondek, M1
Buszman, E1
Yoshikawa, T1
Takahashi, Y1
Kawaguchi, H1
Utsunomiya, S1
Miura, N1
Izumi, H1
Miyoshi, N1
Tanimoto, A1
Tolland, JP1
Murphy, BP1
Boyle, J1
Hall, V1
McKenna, KE1
Elborn, JS1
Nagasawa, M1
Nakamura, S1
Miyazaki, M1
Nojima, Y1
Hayakawa, H1
Kawamura, Y1
Zhang, T1
Li, JL1
Ma, XC1
Xin, J1
Tu, ZH1
Fujita, H1
Matsuo, I2
Mäkinen, M1
Forbes, PD1
Stenbäck, F1
Umezawa, N1
Arakane, K1
Ryu, A1
Mashiko, S1
Hirobe, M1
Nagano, T1
Ferguson, J1
Dawe, R1
Kawada, A1
Hatanaka, K1
Gomi, H1

Trials

1 trial available for ciprofloxacin and Dermatitis, Contact, Phototoxic

ArticleYear
Phototoxicity in quinolones: comparison of ciprofloxacin and grepafloxacin.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40 Suppl A

    Topics: Adolescent; Adult; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; Dose-Response Relat

1997

Other Studies

14 other studies available for ciprofloxacin and Dermatitis, Contact, Phototoxic

ArticleYear
The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents.
    Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22

    Topics: Animals; Anti-Bacterial Agents; Bacteria; CHO Cells; Cricetinae; Dermatitis, Phototoxic; Drug Design

1995
The possible neurobehavioral protective effects of natural antioxidant against phototoxicity attenuation of antimicrobial quinolone group in rats.
    Journal of biochemical and molecular toxicology, 2020, Volume: 34, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Behavior, Animal; Cerebrum; Ciprofloxac

2020
Multi- and unilamellar liposomal encapsulation of ciprofloxacin as ways to modify its phototoxicity and photodegradation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Mar-01, Volume: 129

    Topics: Anti-Bacterial Agents; Biological Availability; Chemistry, Pharmaceutical; Ciprofloxacin; Dermatitis

2019
Photo-induced Stevens-Johnson syndrome.
    Journal of the American Academy of Dermatology, 2014, Volume: 71, Issue:3

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Dermatitis, Phototoxic; Disease Progression; Female; Humans; S

2014
Tyrosine kinase inhibitors enhance ciprofloxacin-induced phototoxicity by inhibiting ABCG2.
    Oncology, 2014, Volume: 87, Issue:6

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member

2014
Effect of fluoroquinolones on melanogenesis in normal human melanocytes HEMn-DP: a comparative in vitro study.
    Cutaneous and ocular toxicology, 2017, Volume: 36, Issue:2

    Topics: Anti-Bacterial Agents; Cell Line; Cell Survival; Ciprofloxacin; Dermatitis, Phototoxic; Epidermal Ce

2017
A dermal phototoxicity study following intravenous infusion administration of ciprofloxacin hydrochloride in the novel microminipigs.
    Toxicologic pathology, 2013, Volume: 41, Issue:1

    Topics: Animals; Ciprofloxacin; Dermatitis, Phototoxic; Disease Models, Animal; Female; Infusions, Intraveno

2013
Ciprofloxacin-induced phototoxicity in an adult cystic fibrosis population.
    Photodermatology, photoimmunology & photomedicine, 2012, Volume: 28, Issue:5

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cystic Fibrosis; Dermatitis, Phototoxic; Female; Humans

2012
[Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent--in vitro and in vivo studies].
    The Japanese journal of antibiotics, 2002, Volume: 55, Issue:3

    Topics: Animals; Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fe

2002
Reliability of phototoxic tests of fluoroquinolones in vitro.
    Acta pharmacologica Sinica, 2003, Volume: 24, Issue:5

    Topics: 3T3 Cells; Animals; Anti-Infective Agents; Ciprofloxacin; Cricetinae; Cricetulus; Dermatitis, Photot

2003
In vitro phototoxic activities of new quinolone antibacterial agents: lipid peroxidative potentials.
    Photodermatology, photoimmunology & photomedicine, 1994, Volume: 10, Issue:5

    Topics: Absorption; Anti-Infective Agents; Azides; Ciprofloxacin; Dermatitis, Phototoxic; Enoxacin; Fluoroqu

1994
Quinolone antibacterials: a new class of photochemical carcinogens.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 37, Issue:3

    Topics: Animals; Anti-Infective Agents; Carcinoma, Squamous Cell; Ciprofloxacin; Dermatitis, Phototoxic; Fle

1997
Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents.
    Archives of biochemistry and biophysics, 1997, Jun-15, Volume: 342, Issue:2

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA; DNA Damage; Enoxacin; Fl

1997
In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation.
    Photodermatology, photoimmunology & photomedicine, 1999, Volume: 15, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Dermatitis, Phototoxic; DNA Damage; Fleroxacin; Fluoroquinolon

1999