Page last updated: 2024-10-25

ciprofloxacin and Crohn Disease

ciprofloxacin has been researched along with Crohn Disease in 59 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

Research Excerpts

ExcerptRelevanceReference
"To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease."9.10Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. ( Dejaco, C; Harrer, M; Miehsler, W; Reinisch, W; Vogelsang, H; Waldhoer, T, 2003)
"Remission and response of perianal fistulas were defined as closure of all fistulas and closure of at least 50% of fistulas that were draining at baseline, respectively."6.74Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study. ( Bernstein, CN; Bitton, A; Cockeram, A; Feagan, BG; Mahadevan, U; Sandborn, WJ; Thia, KT; Wong, C, 2009)
"Ciprofloxacin is effective in perianal Crohn's disease but after treatment discontinuation symptoms reoccur."6.71Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study. ( Drapers, JA; Felt-Bersma, RJ; Hansen, BE; Kuipers, EJ; van der Woude, CJ; van Tilburg, AJ; West, RL, 2004)
"In this study we aimed to determine the microorganisms found in perianal fistulas in Crohn's disease and whether treatment with ciprofloxacin affects these microorganisms."5.11Perianal fistulas in Crohn's disease are predominantly colonized by skin flora: implications for antibiotic treatment? ( Boelens, HA; Endtz, HP; Hansen, BE; Kuipers, EJ; Kusters, JG; Ouwedijk, M; Van der Woude, CJ; West, RL, 2005)
"To evaluate, in a prospective, open-label study, the influence of antibiotics and azathioprine on the clinical outcome of perianal fistulas in patients with Crohn's disease."5.10Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. ( Dejaco, C; Harrer, M; Miehsler, W; Reinisch, W; Vogelsang, H; Waldhoer, T, 2003)
"Microorganisms, their ciprofloxacin resistance, and clinical outcomes were retrospectively analyzed in 78 CD patients with intra-abdominal abscesses, who underwent percutaneous drainage between March 1991, and November 2011."3.80Ciprofloxacin usage and bacterial resistance patterns in Crohn's disease patients with abscesses. ( Byeon, JS; Duk Ye, B; Jung, KW; Kim, JH; Kim, KJ; Lee, SO; Myung, SJ; Park, SK; Sik Yu, C; Yang, DH; Yang, SK, 2014)
"Fifty-two patients (median age 36 yr) with draining perianal fistulas were treated with ciprofloxacin (N = 49) or metronidazole (N = 3) for a median duration of 7 wk."3.74NOD2/CARD15 gene variants are linked to failure of antibiotic treatment in perianal fistulating Crohn's disease. ( Angelberger, S; Dejaco, C; Lichtenberger, C; Miehsler, W; Reinisch, W; Schaeffeler, E; Schwab, M; Teml, A; Vogelsang, H; Waldhoer, T; Wehkamp, J, 2008)
"coli are present in Crohn's disease, but their role in pathogenesis is uncertain."3.01Randomized Trial of Ciprofloxacin Doxycycline and Hydroxychloroquine Versus Budesonide in Active Crohn's Disease. ( Butterworth, J; Culshaw, K; Dallal, H; Flanagan, PK; Hart, A; Horgan, GW; Iqbal, T; Mansfield, J; Martin, K; Parkes, M; Probert, C; Rhodes, JM; Subramanian, S, 2021)
"Remission and response of perianal fistulas were defined as closure of all fistulas and closure of at least 50% of fistulas that were draining at baseline, respectively."2.74Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study. ( Bernstein, CN; Bitton, A; Cockeram, A; Feagan, BG; Mahadevan, U; Sandborn, WJ; Thia, KT; Wong, C, 2009)
"Relapse was defined as an increase in CDAI of >100 points."2.71Lactobacillus GG in inducing and maintaining remission of Crohn's disease. ( Herfarth, HH; Rath, HC; Sartor, RB; Schultz, M; Timmer, A; Vanderhoof, JA, 2004)
"Ciprofloxacin is effective in perianal Crohn's disease but after treatment discontinuation symptoms reoccur."2.71Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study. ( Drapers, JA; Felt-Bersma, RJ; Hansen, BE; Kuipers, EJ; van der Woude, CJ; van Tilburg, AJ; West, RL, 2004)
"In patients with active Crohn's disease of the ileum, the addition of ciprofloxacin and metronidazole to budesonide is an ineffective intervention, but this antibiotic combination may improve outcome when there is involvement of the colon."2.70Combined budesonide and antibiotic therapy for active Crohn's disease: a randomized controlled trial. ( Bitton, A; Cohen, A; Croitoru, K; Drouin, E; Feagan, BG; Greenberg, GR; Leddin, DJ; Mikolainis, S; Seidman, E; Steinhart, AH; Vandervoort, M; Wong, CJ, 2002)
"The etiology of Crohn's disease remains uncertain, and to date no therapy is curative."2.42Antibiotics should be used as first-line therapy for Crohn's disease. ( Greenberg, GR, 2004)
" Moreover, long-term use of glucocorticosteroids is associated with serious and sometimes irreversible side effects."2.42An historical overview of the treatment of Crohn's disease: why do we need biological therapies? ( Rutgeerts, PJ, 2004)
"In general, patients with Crohn's disease are not usually offered IPAA, because recurrence of disease, fistulas, abscesses, and strictures may lead to a higher incidence of pouch failure."2.41Complications after ileal pouch-anal anastomosis. ( Lichtenstein, GR; Stein, RB, 2000)
"Many of the perianal lesions of Crohn's disease respond to short-term metronidazole, and the medium-term (3-6 months) use of broad-spectrum antibiotics, most recently ciprofloxacin, has shown promising results."2.39On the use of antibiotics in Crohn's disease. ( Van Kruiningen, HJ, 1995)
"Stool samples and rectal and perianal fistula swabs were collected."1.72A Microbial Signature for Paediatric Perianal Crohn's Disease. ( Albenberg, L; Baldassano, RN; Bittinger, K; Breton, J; Devas, N; Hwang, R; Kachelries, K; Mattei, P; Rowley, S; Tanes, C; Tu, V; Wu, GD, 2022)
"The elective treatment for acute pouchitis is antibiotics."1.56Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on pouchitis in ulcerative colitis. Part 2: Treatment. ( Barreiro-de Acosta, M; Beltrán, B; Chaparro, M; Espín, E; Ferrer Bradley, I; Gisbert, JP; Guarner, F; Gutiérrez, A; Marín-Jimenez, I; Nos, P; Rodríguez-Lago, I, 2020)
"Ciprofloxacin was selected because of its extensive coverage for intestinal flora, relatively favorable side-effect profile and preliminary data suggesting its efficacy in the treatment of active Crohn's Disease."1.43Methacrylate micro/nano particles prepared by spray drying: a preliminary in vitro/in vivo study. ( Marín Boscá, MT; Muñoz Ortega, B; Sallam, MA, 2016)
"We report three patients with terminal ileitis and positive fecal cultures with Yersinia pseudotuberculosis."1.40Difficulties in diagnosing terminal ileitis due to Yersinia pseudotuberculosis. ( Frénay, IH; Fruth, A; Kuijper, EJ; Notermans, DW; Oostvogel, PM; Wunderink, HF, 2014)
"Fistulas were treated with antibiotics in 59."1.38Genital fistulas in female Crohn's disease patients.: clinical characteristics and response to therapy. ( Bermejo, F; de la Poza, G; Gisbert, JP; López-Sanroman, A; Marín-Jimenez, I; Muriel, A; Opio, V; Taxonera, C, 2012)
"CD-associated perianal fistulas are mainly complex."1.38Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy. ( Assulin, Y; Beer-Gabel, M; Chowers, Y; Lahat, A, 2012)
"Nevertheless, patients with perianal fistulas and CARD15 mutations showed worse response to antibiotics."1.37CARD15 mutations and perianal fistulating Crohn's disease: correlation and predictive value of antibiotic response. ( Andrade, P; Donato, MM; Ferreira, M; Freire, P; Portela, F; Sofia, C, 2011)
"Ampicillin was not effective against intracellular E."1.35Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics. ( Campbell, BJ; Edwards, SW; Hart, CA; Martin, HM; Rhodes, JM; Roberts, CL; Subramanian, S, 2008)
"paratuberculosis; isolates from Crohn's disease patients tended to be more susceptible than were bovine-origin isolates."1.35Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro. ( Collins, MT; Shin, SJ, 2008)
"Colonoscopy diagnosed IBD, a Crohn's disease-like pattern."1.35De-novo [corrected] post renal transplantation inflammatory bowel disease. ( Al-Otaibi, T; Balaha, MA; El-Sayed, A; Elsisi, A; Halim, MA; Nair, P; Nampoory, MR; Said, T, 2008)
"Perianal fistulizing Crohn's disease (PFCD) treatment is based on fistula drainage, antibiotics, immunosuppressant (IS) drugs, and infliximab."1.35Predicting factors of fistula healing and clinical remission after infliximab-based combined therapy for perianal fistulizing Crohn's disease. ( Koning, E; Lerebours, E; Michot, F; Savoye, G; Savoye-Collet, C; Tougeron, D, 2009)
"A pediatric patient with Crohn's disease and colitis with cryptitis developed a prolonged Q-T interval within 48 hours of treatment with ciprofloxacin."1.35Ciprofloxacin-induced Q-T interval prolongation. ( Knorr, JP; Moshfeghi, M; Sokoloski, MC, 2008)
"Recto-urethral fistulas due to Crohn's disease are very uncommon."1.35[Urethral fistula due to Crohn's disease: case report of successful conservative management]. ( Borovicka, J; Engeler, DS; Hetzer, FH; Meyer, D; Schmid, HP; Schwab, C, 2008)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (11.86)18.2507
2000's32 (54.24)29.6817
2010's13 (22.03)24.3611
2020's7 (11.86)2.80

Authors

AuthorsStudies
Subramanian, S2
Roberts, CL1
Hart, CA1
Martin, HM1
Edwards, SW1
Rhodes, JM2
Campbell, BJ1
Shin, SJ1
Collins, MT1
Breton, J1
Tanes, C1
Tu, V1
Albenberg, L1
Rowley, S1
Devas, N1
Hwang, R1
Kachelries, K1
Wu, GD1
Baldassano, RN1
Bittinger, K1
Mattei, P1
Barreiro-de Acosta, M1
Marín-Jimenez, I2
Rodríguez-Lago, I1
Guarner, F1
Espín, E1
Ferrer Bradley, I1
Gutiérrez, A1
Beltrán, B1
Chaparro, M1
Gisbert, JP2
Nos, P1
Limketkai, BN1
Akobeng, AK1
Gordon, M1
Adepoju, AA1
Flanagan, PK1
Horgan, GW1
Martin, K1
Mansfield, J1
Parkes, M1
Hart, A1
Dallal, H1
Iqbal, T1
Butterworth, J1
Culshaw, K1
Probert, C1
Begbey, A1
Guppy, JH1
Mohan, C1
Webster, S1
Effinger, A1
McAllister, M1
Tomaszewska, I1
O'Driscoll, CM1
Taylor, M1
Gomersall, S1
Heaton, J1
Smith, KL1
Sarcevica, I1
Young, SL1
Fotaki, N1
Kayal, M1
Bhagya Rao, B1
Bhattacharya, A1
Ungaro, R1
Cazals-Hatem, D1
Kale-Pradhan, PB1
Zhao, JJ1
Palmer, JR1
Wilhelm, SM1
Herfarth, HH2
Katz, JA1
Hanauer, SB1
Sandborn, WJ2
Loftus, EV1
Sands, BE2
Galanko, JA1
Walkup, D1
Isaacs, KL1
Martin, CF1
Sandler, RS1
Sartor, RB2
Dewint, P1
Hansen, BE3
Verhey, E1
Oldenburg, B1
Hommes, DW1
Pierik, M1
Ponsioen, CI1
van Dullemen, HM1
Russel, M1
van Bodegraven, AA1
van der Woude, CJ3
Gupta, NK1
Masia, R1
Wunderink, HF1
Oostvogel, PM1
Frénay, IH1
Notermans, DW1
Fruth, A1
Kuijper, EJ1
Park, SK1
Kim, KJ1
Lee, SO1
Yang, DH1
Jung, KW1
Duk Ye, B1
Byeon, JS1
Myung, SJ1
Yang, SK1
Kim, JH1
Sik Yu, C1
Su, JW1
Ma, JJ1
Zhang, HJ1
Muñoz Ortega, B1
Sallam, MA1
Marín Boscá, MT1
Massa, AF1
Campos, MA1
Baptista, A1
Costa, C1
Lima, O1
Osório Ferreira, E1
Halim, MA1
Al-Otaibi, T1
Elsisi, A1
El-Sayed, A1
Nair, P1
Said, T1
Balaha, MA1
Nampoory, MR1
Thia, KT1
Mahadevan, U1
Feagan, BG3
Wong, C1
Cockeram, A1
Bitton, A2
Bernstein, CN1
Tougeron, D1
Savoye, G1
Savoye-Collet, C1
Koning, E1
Michot, F1
Lerebours, E1
Freire, P1
Portela, F1
Donato, MM1
Ferreira, M1
Andrade, P1
Sofia, C1
de la Poza, G1
López-Sanroman, A1
Taxonera, C1
Bermejo, F1
Opio, V1
Muriel, A1
Lahat, A1
Assulin, Y1
Beer-Gabel, M1
Chowers, Y1
Bamias, G1
Marini, M1
Moskaluk, CA1
Odashima, M1
Ross, WG1
Rivera-Nieves, J1
Cominelli, F1
Bataille, L1
Rahier, J1
Geubel, A1
Tomás, ME1
Pérez Carreras, M1
Morillasa, JD1
Castellano, G1
Solís, JA1
Ishikawa, T1
Okamura, S1
Oshimoto, H1
Kobayashi, R1
Mori, M1
Castiglione, F1
Rispo, A1
Di Girolamo, E1
Cozzolino, A1
Manguso, F1
Grassia, R1
Mazzacca, G1
Dejaco, C2
Harrer, M1
Waldhoer, T2
Miehsler, W2
Vogelsang, H2
Reinisch, W2
Schultz, M1
Timmer, A1
Vanderhoof, JA1
Rath, HC1
Greenberg, GR3
Wild, GE1
Mow, WS1
Landers, CJ1
Steinhart, AH2
Croitoru, K2
Seidman, E2
Targan, SR1
Rutgeerts, PJ1
West, RL2
Felt-Bersma, RJ1
van Tilburg, AJ1
Drapers, JA1
Kuipers, EJ2
Gionchetti, P1
Rizzello, F1
Morselli, C1
Romagnoli, R1
Campieri, M1
Endtz, HP1
Ouwedijk, M1
Boelens, HA1
Kusters, JG1
Dignass, AU1
Elliott, PR1
Moore, GT1
Bell, SJ1
Connell, WR1
Bressler, B1
Atienza, P1
Myers, AL1
Colombo, J1
Jackson, MA1
Harrison, CJ1
Roberts, CR1
Knorr, JP1
Moshfeghi, M1
Sokoloski, MC1
Angelberger, S1
Wehkamp, J1
Lichtenberger, C1
Schaeffeler, E1
Schwab, M1
Teml, A1
Schwab, C1
Meyer, D1
Hetzer, FH1
Borovicka, J1
Schmid, HP1
Engeler, DS1
Van Kruiningen, HJ1
Prantera, C3
Kohn, A2
Zannoni, F2
Spimpolo, N1
Bonfa, M1
Peppercorn, MA1
Scribano, ML2
Berto, E2
Andreoli, A1
Luzi, C1
Shetty, AK1
Udall, J1
Schmidt-Sommerfeld, E1
Falasco, G1
Colombel, JF1
Lémann, M1
Cassagnou, M1
Bouhnik, Y1
Duclos, B1
Dupas, JL1
Notteghem, B1
Mary, JY1
Stein, RB1
Lichtenstein, GR1
Marteau, P1
Seksik, P1
Arnold, GL1
Beaves, MR1
Pryjdun, VO1
Mook, WJ1
Wong, CJ1
Vandervoort, M1
Mikolainis, S1
Leddin, DJ1
Drouin, E1
Cohen, A1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Randomised Study to Compare Combination Antibiotic Therapy (Ciprofloxacin, Doxycycline and Hydroxychloroquine) With Standard Therapy (Budesonide) in the Treatment of Active Crohn's Disease[NCT01783106]Phase 259 participants (Actual)Interventional2014-02-01Completed
Adalimumab for the Treatment of Perianal Fistulas in Crohn's Disease More Effective Alone or Combined to Ciprofloxacin[NCT00736983]Phase 376 participants (Actual)Interventional2008-09-30Completed
A Prospective Longitudinal Study on the Effect of Tight Control Management on Perianal Crohn's Disease[NCT03861689]40 participants (Anticipated)Interventional2019-07-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for ciprofloxacin and Crohn Disease

ArticleYear
Probiotics for induction of remission in Crohn's disease.
    The Cochrane database of systematic reviews, 2020, 07-17, Volume: 7

    Topics: Adult; Anti-Bacterial Agents; Bifidobacterium longum; Ciprofloxacin; Crohn Disease; Gastrointestinal

2020
[Histoseminar on inflammatory bowel diseases (IBD): Case n
    Annales de pathologie, 2017, Volume: 37, Issue:4

    Topics: Acute Disease; Adult; Anti-Bacterial Agents; Biopsy; Ciprofloxacin; Colon; Crohn Disease; Diagnosis,

2017
The role of antimicrobials in Crohn's disease.
    Expert review of gastroenterology & hepatology, 2013, Volume: 7, Issue:3

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Clarithromycin; Crohn Disease; Humans; Metronidazole; R

2013
Use of antibiotics in patients with Crohn's disease: a systematic review and meta-analysis.
    Journal of digestive diseases, 2015, Volume: 16, Issue:2

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Humans; Randomized Controlled Trials as Topic

2015
Antibiotics should be used as first-line therapy for Crohn's disease.
    Inflammatory bowel diseases, 2004, Volume: 10, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Humans; Imipenem; Metronidazole; Time

2004
The role of antibiotics in the management of Crohn's disease.
    Inflammatory bowel diseases, 2004, Volume: 10, Issue:3

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Clinical Trials as Topic; Crohn Disease; Drug Therapy, Combina

2004
An historical overview of the treatment of Crohn's disease: why do we need biological therapies?
    Reviews in gastroenterological disorders, 2004, Volume: 4 Suppl 3

    Topics: Anti-Infective Agents; Biological Therapy; Ciprofloxacin; Crohn Disease; Glucocorticoids; Humans; Im

2004
Management of inflammatory bowel disease: does rifaximin offer any promise?
    Chemotherapy, 2005, Volume: 51 Suppl 1

    Topics: Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Clinical Trials as Topic; Colitis, Ulcerative; Crohn

2005
Review article: Medical therapy for fistulizing Crohn's disease.
    Alimentary pharmacology & therapeutics, 2006, Nov-01, Volume: 24, Issue:9

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Diseas

2006
[Refractory perineal fistulas in Crohn's disease].
    Gastroenterologie clinique et biologique, 2007, Volume: 31, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Diseas

2007
On the use of antibiotics in Crohn's disease.
    Journal of clinical gastroenterology, 1995, Volume: 20, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Dogs; Humans; Metronidazole

1995
Complications after ileal pouch-anal anastomosis.
    Seminars in gastrointestinal disease, 2000, Volume: 11, Issue:1

    Topics: Anastomosis, Surgical; Ciprofloxacin; Colitis, Ulcerative; Crohn Disease; Humans; Male; Metronidazol

2000

Trials

16 trials available for ciprofloxacin and Crohn Disease

ArticleYear
Randomized Trial of Ciprofloxacin Doxycycline and Hydroxychloroquine Versus Budesonide in Active Crohn's Disease.
    Digestive diseases and sciences, 2021, Volume: 66, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Budesonide; Ciprofloxacin; Crohn Disease; Cross-Ove

2021
Ciprofloxacin for the prevention of postoperative recurrence in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study.
    Inflammatory bowel diseases, 2013, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Anastomosis, Surgical; Anti-Infective Agents; Ciprofloxacin; Crohn Disease; Doubl

2013
Adalimumab combined with ciprofloxacin is superior to adalimumab monotherapy in perianal fistula closure in Crohn's disease: a randomised, double-blind, placebo controlled trial (ADAFI).
    Gut, 2014, Volume: 63, Issue:2

    Topics: Adalimumab; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Mo

2014
Ciprofloxacin or metronidazole for the treatment of perianal fistulas in patients with Crohn's disease: a randomized, double-blind, placebo-controlled pilot study.
    Inflammatory bowel diseases, 2009, Volume: 15, Issue:1

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Crohn Disease; Double-Blind Method; Female; Humans; Mal

2009
Metronidazole plus ciprofloxacin therapy for active Crohn's disease.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:4

    Topics: Adult; Anti-Infective Agents; Blood Sedimentation; C-Reactive Protein; Ciprofloxacin; Crohn Disease;

2003
Antibiotic treatment of small bowel bacterial overgrowth in patients with Crohn's disease.
    Alimentary pharmacology & therapeutics, 2003, Volume: 18, Issue:11-12

    Topics: Adult; Aged; Anti-Infective Agents; Bacterial Infections; Breath Tests; Ciprofloxacin; Colonic Disea

2003
Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease.
    Alimentary pharmacology & therapeutics, 2003, Volume: 18, Issue:11-12

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anus Diseases; Azathioprine;

2003
Lactobacillus GG in inducing and maintaining remission of Crohn's disease.
    BMC gastroenterology, 2004, Mar-15, Volume: 4

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Double-Blind Method; Drug Therapy, Combination;

2004
High-level serum antibodies to bacterial antigens are associated with antibiotic-induced clinical remission in Crohn's disease: a pilot study.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:7-8

    Topics: Anti-Infective Agents; Antibodies, Antineutrophil Cytoplasmic; Antigens, Bacterial; Budesonide; Cipr

2004
Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20, Issue:11-12

    Topics: Adolescent; Adult; Anti-Infective Agents; Antibodies, Monoclonal; Ciprofloxacin; Crohn Disease; Doub

2004
Perianal fistulas in Crohn's disease are predominantly colonized by skin flora: implications for antibiotic treatment?
    Digestive diseases and sciences, 2005, Volume: 50, Issue:7

    Topics: Adult; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Corynebacterium Infections; Crohn

2005
Metronidazole plus ciprofloxacin in the treatment of active, refractory Crohn's disease: results of an open study.
    Journal of clinical gastroenterology, 1994, Volume: 19, Issue:1

    Topics: Adult; Aged; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Female; Humans; Male; Metronid

1994
An antibiotic regimen for the treatment of active Crohn's disease: a randomized, controlled clinical trial of metronidazole plus ciprofloxacin.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Crohn Disea

1996
A controlled trial comparing ciprofloxacin with mesalazine for the treatment of active Crohn's disease. Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives (GETAID).
    The American journal of gastroenterology, 1999, Volume: 94, Issue:3

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin; Crohn Disease;

1999
Preliminary study of ciprofloxacin in active Crohn's disease.
    Inflammatory bowel diseases, 2002, Volume: 8, Issue:1

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Crohn Disease; Female; Humans; Male; Middle Aged;

2002
Combined budesonide and antibiotic therapy for active Crohn's disease: a randomized controlled trial.
    Gastroenterology, 2002, Volume: 123, Issue:1

    Topics: Administration, Oral; Adult; Anti-Infective Agents; Budesonide; Ciprofloxacin; Colon; Crohn Disease;

2002

Other Studies

31 other studies available for ciprofloxacin and Crohn Disease

ArticleYear
Replication of Colonic Crohn's Disease Mucosal Escherichia coli Isolates within Macrophages and Their Susceptibility to Antibiotics.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cell Line; Cells, Cultured; Colon; Crohn Disease; Culture Media; Esc

2008
Thiopurine drugs azathioprine and 6-mercaptopurine inhibit Mycobacterium paratuberculosis growth in vitro.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Animals; Azathioprine; Bacteriological Techniques; Cattle; Cattle Diseases; Colony Count, Microbial;

2008
A Microbial Signature for Paediatric Perianal Crohn's Disease.
    Journal of Crohn's & colitis, 2022, Aug-30, Volume: 16, Issue:8

    Topics: Ciprofloxacin; Crohn Disease; Ecosystem; Humans; Rectal Fistula; Treatment Outcome

2022
Recommendations of the Spanish Working Group on Crohn's Disease and Ulcerative Colitis (GETECCU) on pouchitis in ulcerative colitis. Part 2: Treatment.
    Gastroenterologia y hepatologia, 2020, Volume: 43, Issue:10

    Topics: Acute Disease; Advisory Committees; Algorithms; Anti-Bacterial Agents; Biological Products; Budesoni

2020
    BMJ case reports, 2020, Dec-31, Volume: 13, Issue:12

    Topics: Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ciprofloxacin; Cl

2020
Investigating the Impact of Crohn's Disease on the Bioaccessibility of a Lipid-Based Formulation with an In Vitro Dynamic Gastrointestinal Model.
    Molecular pharmaceutics, 2021, 04-05, Volume: 18, Issue:4

    Topics: Administration, Oral; Animals; Bile Acids and Salts; Ciprofloxacin; Crohn Disease; Excipients; Fasti

2021
Clinical Challenge: From Ulcerative Colitis to Crohn's Disease-Like Pouch Inflammation.
    Digestive diseases and sciences, 2021, Volume: 66, Issue:10

    Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Ciprofloxacin; Colitis, Ulcerative; Crohn Di

2021
Cord colitis syndrome: a cause of granulomatous inflammation in the upper and lower gastrointestinal tract.
    The American journal of surgical pathology, 2013, Volume: 37, Issue:7

    Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Colitis; Cord Blood Stem Cell Transplantation; Crohn Di

2013
Difficulties in diagnosing terminal ileitis due to Yersinia pseudotuberculosis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2014, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacteriological Techniques; Ciprofloxacin; Crohn Disease;

2014
Ciprofloxacin usage and bacterial resistance patterns in Crohn's disease patients with abscesses.
    Journal of clinical gastroenterology, 2014, Volume: 48, Issue:8

    Topics: Abdominal Abscess; Adolescent; Adult; Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Drainage;

2014
Methacrylate micro/nano particles prepared by spray drying: a preliminary in vitro/in vivo study.
    Drug delivery, 2016, Volume: 23, Issue:7

    Topics: Acrylic Resins; Administration, Oral; Ciprofloxacin; Crohn Disease; Desiccation; Drug Liberation; Ex

2016
Paediatric anogenital Crohn's disease 11 years after Lichen planus - same background for two different entities?
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2016, Volume: 30, Issue:7

    Topics: Anal Canal; Azathioprine; Child; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Female; Ge

2016
De-novo [corrected] post renal transplantation inflammatory bowel disease.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2008, Volume: 19, Issue:4

    Topics: Adult; Aminosalicylic Acids; Ciprofloxacin; Crohn Disease; Humans; Immunosuppressive Agents; Inflamm

2008
Predicting factors of fistula healing and clinical remission after infliximab-based combined therapy for perianal fistulizing Crohn's disease.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Ciprof

2009
CARD15 mutations and perianal fistulating Crohn's disease: correlation and predictive value of antibiotic response.
    Digestive diseases and sciences, 2011, Volume: 56, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Female; Genet

2011
Genital fistulas in female Crohn's disease patients.: clinical characteristics and response to therapy.
    Journal of Crohn's & colitis, 2012, Volume: 6, Issue:3

    Topics: Adalimumab; Adolescent; Adult; Age Factors; Anti-Infective Agents; Anti-Inflammatory Agents; Antibod

2012
Endoscopic ultrasound for perianal Crohn's disease: disease and fistula characteristics, and impact on therapy.
    Journal of Crohn's & colitis, 2012, Volume: 6, Issue:3

    Topics: Abscess; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Infective Agents; Anti-Inflammatory

2012
Down-regulation of intestinal lymphocyte activation and Th1 cytokine production by antibiotic therapy in a murine model of Crohn's disease.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Nov-01, Volume: 169, Issue:9

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Cells, Cultured; Ciprofloxacin; Crohn Disease;

2002
Delayed and prolonged cholestatic hepatitis with ductopenia after long-term ciprofloxacin therapy for Crohn's disease.
    Journal of hepatology, 2002, Volume: 37, Issue:5

    Topics: Anti-Infective Agents; Bile Ducts; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Dise

2002
[Rupture of the Achilles' tendon secondary to levofloxacin].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Achilles Tendon; Adult; Ceftriaxone; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Humans

2003
[Management of perianal fistulizing Crohn's disease: a conservative approach].
    Deutsche medizinische Wochenschrift (1946), 2005, Aug-26, Volume: 130, Issue:34-35

    Topics: Anti-Infective Agents; Ciprofloxacin; Combined Modality Therapy; Crohn Disease; Fecal Incontinence;

2005
Severe recurrent Crohn's disease of the ileocolonic anastomosis disappearing completely with antibacterial therapy.
    Gut, 2005, Volume: 54, Issue:12

    Topics: Adult; Anastomosis, Surgical; Anti-Bacterial Agents; Ciprofloxacin; Colon; Crohn Disease; Humans; Il

2005
Tuberculous colitis mimicking Crohn disease.
    Journal of pediatric gastroenterology and nutrition, 2007, Volume: 45, Issue:5

    Topics: Abdominal Pain; Adolescent; Anastomosis, Surgical; Anti-Infective Agents; Antitubercular Agents; App

2007
Ciprofloxacin-induced Q-T interval prolongation.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2008, Mar-15, Volume: 65, Issue:6

    Topics: Abscess; Acetamides; Adolescent; Anti-Infective Agents; Aztreonam; Bradycardia; Ciprofloxacin; Crohn

2008
NOD2/CARD15 gene variants are linked to failure of antibiotic treatment in perianal fistulating Crohn's disease.
    The American journal of gastroenterology, 2008, Volume: 103, Issue:5

    Topics: Adult; Alleles; Anti-Infective Agents; beta-Defensins; Ciprofloxacin; Crohn Disease; Female; Genetic

2008
[Urethral fistula due to Crohn's disease: case report of successful conservative management].
    Der Urologe. Ausg. A, 2008, Volume: 47, Issue:10

    Topics: Azathioprine; Ciprofloxacin; Crohn Disease; Cystoscopy; Cystostomy; Diagnosis, Differential; Drug Th

2008
Is there a role for antibiotics as primary therapy in Crohn's ileitis?
    Journal of clinical gastroenterology, 1993, Volume: 17, Issue:3

    Topics: Adult; Aged; Ciprofloxacin; Crohn Disease; Female; Humans; Ileitis; Male; Middle Aged

1993
Highly destructive perianal Crohn's disease.
    Journal of the National Medical Association, 1998, Volume: 90, Issue:8

    Topics: Adolescent; Anti-Infective Agents; Anti-Inflammatory Agents; Anus Diseases; Ciprofloxacin; Colostomy

1998
Use of antibiotics in the treatment of active Crohn's disease: experience with metronidazole and ciprofloxacin.
    Italian journal of gastroenterology and hepatology, 1998, Volume: 30, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Cro

1998
Case problem: medical nutrition therapy for a patient with Crohn's disease.
    Journal of the American Dietetic Association, 2000, Volume: 100, Issue:4

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Body Weight; Ciprofloxacin; Crohn Disease; Diarrhea

2000
[Role of prebiotics and probiotics in therapeutic management of cryptogenetic inflammatory bowel disease].
    Gastroenterologie clinique et biologique, 2001, Volume: 25, Issue:2 Pt 2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Ciprofloxacin

2001