Page last updated: 2024-10-25

ciprofloxacin and Corneal Ulcer

ciprofloxacin has been researched along with Corneal Ulcer in 76 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Corneal Ulcer: Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.

Research Excerpts

ExcerptRelevanceReference
"Knowledge on possible delaying effects of topical ciprofloxacin on corneal ulcer healing is scarce in avian patients."9.69Evaluation of delaying effects of different short-term dosage regimens of topical ciprofloxacin on corneal ulcer healing in an avian model. ( Masoudian, M; Mosleh, N; Namazi, F; Shomali, T; Tavangarrad, N, 2023)
"This prospective, randomized, double-masked controlled clinical trial was conducted on 41 patients (41 eyes) with suspected bacterial corneal ulcers who were randomized into 2 groups: 23 patients were in the lomefloxacin group and 18 patients in the ciprofloxacin group."9.11Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers. ( Booranapong, W; Kosrirukvongs, P; Prabhasawat, P; Srivannaboon, S; Suttiprakarn, P, 2004)
"To assess topical ciprofloxacin in patients with moderate severity of suspected bacterial corneal ulcers."9.09Topical ciprofloxacin for bacterial corneal ulcer. ( Buranapongs, W; Kosrirukvongs, P, 2000)
"3% monotherapy is equivalent clinically and statistically to standard therapy (fortified tobramycin-cefazolin) for the treatment of bacterial corneal ulcers and produces significantly less discomfort."9.08Comparison of ciprofloxacin ophthalmic solution 0.3% to fortified tobramycin-cefazolin in treating bacterial corneal ulcers. Ciprofloxacin Bacterial Keratitis Study Group. ( Adenis, JP; Badrinath, SS; Caldwell, DR; Eiferman, RA; Hyndiuk, RA; Katz, HR; Klauss, V; Reddy, MK; Rosenwasser, GO; Santos, CI, 1996)
"3% is at least as effective as ciprofloxacin at healing corneal ulcers infected with Pseudomonas aeruginosa when gatifloxacin is administered less frequently than ciprofloxacin."7.73Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits. ( Carrier, M; Jensen, H; Short, B; Zerouala, C, 2005)
"Knowledge on possible delaying effects of topical ciprofloxacin on corneal ulcer healing is scarce in avian patients."5.69Evaluation of delaying effects of different short-term dosage regimens of topical ciprofloxacin on corneal ulcer healing in an avian model. ( Masoudian, M; Mosleh, N; Namazi, F; Shomali, T; Tavangarrad, N, 2023)
"Honey based ophthalmic drop can acceleratethe corneal epithelial defect healing in patients with foreign body induced corneal ulcer, compared to ophthalmic ciprofloxacin as a standard treatment."5.41Efficacy of Honey-based Ophthalmic Formulation in Patients with Corneal Ulcer: A Randomized Clinical Trial. ( Akbarizadeh, AR; Daneshamouz, S; Heydari, M; Nejabat, M; Soltanzadeh, K; Yasemi, M, 2021)
"Lomefloxacin was found to have significant efficacy in the healing of Staphylococcus aureus-induced corneal ulcers and associated lesions."5.30Comparative studies on topical lomefloxacin and ciprofloxacin on ocular kinetic and experimental corneal ulcer. ( Agarwal, HC; Biswas, NR; Gupta, SK; Gupta, YK; Velpandian, T, 1999)
"This prospective, randomized, double-masked controlled clinical trial was conducted on 41 patients (41 eyes) with suspected bacterial corneal ulcers who were randomized into 2 groups: 23 patients were in the lomefloxacin group and 18 patients in the ciprofloxacin group."5.11Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers. ( Booranapong, W; Kosrirukvongs, P; Prabhasawat, P; Srivannaboon, S; Suttiprakarn, P, 2004)
"To assess topical ciprofloxacin in patients with moderate severity of suspected bacterial corneal ulcers."5.09Topical ciprofloxacin for bacterial corneal ulcer. ( Buranapongs, W; Kosrirukvongs, P, 2000)
"3% monotherapy is equivalent clinically and statistically to standard therapy (fortified tobramycin-cefazolin) for the treatment of bacterial corneal ulcers and produces significantly less discomfort."5.08Comparison of ciprofloxacin ophthalmic solution 0.3% to fortified tobramycin-cefazolin in treating bacterial corneal ulcers. Ciprofloxacin Bacterial Keratitis Study Group. ( Adenis, JP; Badrinath, SS; Caldwell, DR; Eiferman, RA; Hyndiuk, RA; Katz, HR; Klauss, V; Reddy, MK; Rosenwasser, GO; Santos, CI, 1996)
"To compare the therapeutic effectiveness of a single intrastromal dose of gentamycin, tobramycin, ciprofloxacin and ofloxacin for the treatment of corneal ulcers due to Pseudomonas aeruginosa."3.75[Bacterial corneal ulcer treated with intrastromal antibiotic. Experimental model in vivo]. ( Naranjo-Tackman, R; Stangogiannis-Druya, C; Stangogiannis-Druya, E; Vanzzini, V; Villar-Kurí, J, 2009)
"3% is at least as effective as ciprofloxacin at healing corneal ulcers infected with Pseudomonas aeruginosa when gatifloxacin is administered less frequently than ciprofloxacin."3.73Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits. ( Carrier, M; Jensen, H; Short, B; Zerouala, C, 2005)
" Twelve days later, she was diagnosed with posterior scleritis and treated with oral ciprofloxacin."3.73Posterior scleritis secondary to Pseudomonas aeruginosa keratitis. ( Dastjerdi, M; Fahim, K; Houghton, O; Mian, SI, 2005)
"A patient underwent intensive topical treatment of an infectious corneal ulcer with commercially available ciprofloxacin 0."3.71Scanning electron microscopic study of a Ciloxan bottle blocked by ciprofloxacin crystals. ( John, T, 2001)
"To report a clinical case of a 21-year old male with a severe corneal abscess due to Pseudomonas aeruginosa refractory to intensive treatment with topical Ciprofloxacin."3.71[Pseudomonas aeruginosa corneal abscess refractory to fluoroquinolones]. ( Alós Cortés, JI; Arteaga Sánchez, A; Díaz Valle, D; Díaz-Valle, T; Poza Morales, Y; Toledano Fernández, N, 2002)
"Devices such as contact lenses and collagen shields have been used to improve the antibiotic bioavailability of eye drops formulations in the treatment of ulcerative keratitis."1.56PVA/anionic collagen membranes as drug carriers of ciprofloxacin hydrochloride with sustained antibacterial activity and potential use in the treatment of ulcerative keratitis. ( Chaud, MV; da Conceição Amaro Martins, V; Daza, JHU; Lopes Baratella da Cunha Camargo, I; Maria de Guzzi Plepis, A; Righetto, GM, 2020)
"Ciprofloxacin resistance was found in 8 (17."1.37Antibiotic resistance in microbial keratitis: ten-year experience of corneal scrapes in the United Kingdom. ( Baker, M; Gurbaxani, A; Nash, J; Shalchi, Z, 2011)
"Levofloxacin 1."1.36Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models. ( Gordon, YJ; Kowalski, RP; Mah, FS; Romanowski, EG; Shanks, RM, 2010)
"One month later, a recurrence of PUK on the donor button was noted."1.35Recurrence of peripheral ulcerative keratitis on the corneoscleral button in a young man treated successfully with oral corticosteroids. ( Bakiah, S; Ibrahim, M; Selvaraja, V; Wahid, WA, 2008)
"An 11-year-old boy, a known case of lamellar ichthyosis, presented with microbial keratitis."1.35Microbial keratitis in a case of lamellar ichthyosis. ( Chaurasia, S; Das, S; Ramamurthy, B, 2008)
"Treatment with ciprofloxacin and amikacin resolved the ulcer."1.33Mycobacterium chelonae keratitis: elucidation of diagnosis through evaluation of smears of fluid from patient's contact lens care system. ( Bottone, EJ; Cho, KW, 2005)
"Fungal corneal ulcers are not uncommon."1.30Infectious keratitis in leprosy. ( Daniel, E; John, D, 1999)
"Ciprofloxacin was not detected by either method in the precipitate obtained from one patient."1.30Antibacterial activity of the white precipitate formed on the corneal surface after treatment with ciprofloxacin ophthalmic solution. ( Joseph, PR; Madhavan, HN; Rao, SK; Sulochana, KN, 1999)
"Lomefloxacin was found to have significant efficacy in the healing of Staphylococcus aureus-induced corneal ulcers and associated lesions."1.30Comparative studies on topical lomefloxacin and ciprofloxacin on ocular kinetic and experimental corneal ulcer. ( Agarwal, HC; Biswas, NR; Gupta, SK; Gupta, YK; Velpandian, T, 1999)
" These results suggest that either salt of prednisolone, when combined with ciprofloxacin, reduces ocular inflammation without affecting the antimicrobial efficacy of the antibiotic."1.29Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis. ( Callegan, MC; Engel, LS; Hill, JM; Hobden, JA; O'Callaghan, RJ, 1993)
"Two patients had acquired immunodeficiency syndrome (AIDS), one was human immunodeficiency virus (HIV)-positive, and the fourth refused HIV testing."1.29Spontaneous ulcerative keratitis in immunocompromised patients. ( Aristimuño, B; Hemady, RK; Nirankari, VS; Rodrigues, MM, 1993)
"Ciprofloxacin appears to be an effective single agent in the treatment of ulcerative keratitis."1.29Comparison of topical ciprofloxacin to conventional antibiotic therapy in the treatment of ulcerative keratitis. ( Abrams, DA; Katz, HR; Parks, DJ; Sarfarazi, FA, 1993)
"Amikacin was more effective in reducing the number of organisms in corneas infected with ATCC-6841 than in corneas infected with the patient isolate (p = 0."1.28Mycobacterium fortuitum keratitis. A comparison of topical ciprofloxacin and amikacin in an animal model. ( Berlin, OG; Bruckner, DA; Holland, GN; Paschal, JF; Phinney, RB; Stevens, RK, 1992)
"Ciprofloxacin is a new quinolone antibiotic with a broad spectrum of activity against most aerobic gram-positive and gram-negative bacteria."1.28Successful treatment of methicillin-resistant Staphylococcus aureus Keratitis with topical ciprofloxacin. ( Fish, LA; Hill, JM; Hobden, JA; Insler, MS; O'Callaghan, RJ; Silbernagel, J, 1991)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's22 (28.95)18.2507
2000's35 (46.05)29.6817
2010's13 (17.11)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
Tavangarrad, N1
Mosleh, N1
Shomali, T1
Namazi, F1
Masoudian, M1
Nejabat, M1
Soltanzadeh, K1
Yasemi, M1
Daneshamouz, S1
Akbarizadeh, AR1
Heydari, M1
Quan, AV1
Huang, AM1
Galor, A1
Díaz Barrón, A1
Sanz Gallen, L1
Hervás Hernandis, JM1
Tarragó Simón, E1
Duch-Samper, AM1
Cornée, C1
Mainguy, A1
Coeuru, D1
Routier, M1
Lebranchu, P1
Vabres, B1
Daza, JHU1
Righetto, GM1
Chaud, MV1
da Conceição Amaro Martins, V1
Lopes Baratella da Cunha Camargo, I1
Maria de Guzzi Plepis, A1
Palioura, S1
Gibbons, A1
Miller, D2
OʼBrien, TP1
Alfonso, EC2
Spierer, O1
Bennett, HY1
Hayes, RA1
O'Hagan, S1
Fennelly, E1
Greenan, E1
Murphy, CC1
Hazlett, LD1
Ekanayaka, SA1
McClellan, SA1
Francis, R1
Kaliamurthy, J3
Kalavathy, CM4
Parmar, P4
Nelson Jesudasan, CA1
Thomas, PA4
Konda, N1
Motukupally, SR1
Garg, P2
Sharma, S2
Ali, MH1
Willcox, MD1
McDonald, EM1
Ram, FS1
Patel, DV1
McGhee, CN1
Sand, D1
She, R1
Shulman, IA1
Chen, DS1
Schur, M1
Hsu, HY1
Fernandes, M1
Vira, D1
Medikonda, R1
Kumar, N1
Wahid, WA1
Selvaraja, V1
Bakiah, S1
Ibrahim, M1
Karicherla, P1
Hobden, JA4
Stangogiannis-Druya, E1
Stangogiannis-Druya, C1
Naranjo-Tackman, R1
Vanzzini, V1
Villar-Kurí, J1
Diec, J1
Carnt, N2
Tilia, D1
Evans, V1
Rao, V1
Ozkan, J1
Holden, BA2
Kowalski, RP4
Romanowski, EG3
Mah, FS3
Shanks, RM1
Gordon, YJ4
Shih, MH1
Huang, FC1
Borsali, E1
Le Bouter, A1
Abdiche, G1
Goldschmdt, P1
Legrand, P1
Batellier, L1
Gleize, D1
Laroche, L1
Chaumeil, C1
Shalchi, Z1
Gurbaxani, A1
Baker, M1
Nash, J1
Salman, A2
Jesudasan, CA3
Donnenfeld, ED1
O'Brien, TP3
Solomon, R1
Perry, HD1
Speaker, MG1
Wittpenn, J1
Sweeney, DF1
Sankaridurg, PR1
Edwards, K1
Stretton, S1
Stapleton, F1
Daines, BS1
Vroman, DT1
Sandoval, HP1
Steed, LL1
Solomon, KD1
Wilhelmus, KR2
Abshire, RL2
Schlech, BA1
Dhaliwal, DK1
Karenchak, LM1
Ritterband, DC1
Lee, KY1
Lim, L1
Barequet, IS1
Denton, P1
Osterhout, GJ1
Tuli, S1
Booranapong, W1
Kosrirukvongs, P2
Prabhasawat, P1
Srivannaboon, S1
Suttiprakarn, P1
Ramalingam, K1
Hyon, JY1
Joo, MJ1
Hose, S1
Sinha, D1
Dick, JD1
Weyenberg, W1
Vermeire, A1
Dhondt, MM1
Adriaens, E1
Kestelyn, P1
Remon, JP1
Ludwig, A1
Jensen, H1
Zerouala, C1
Carrier, M1
Short, B1
Bottone, EJ1
Cho, KW1
Fahim, K1
Houghton, O1
Dastjerdi, M1
Mian, SI1
Caballero, AR1
Marquart, ME1
O'Callaghan, RJ4
Thibodeaux, BA1
Johnston, KH1
Dajcs, JJ1
Prasanth, DA1
Schornack, MM1
Peterson, D1
Sharma, N1
Sinha, R1
Singhvi, A1
Tandon, R1
Yates, KA1
Chaurasia, S1
Das, S1
Ramamurthy, B1
Lee, SM1
Kim, MK1
Lee, JL1
Wee, WR1
Lee, JH1
Guzek, JP1
Chacko, D1
Kettering, JD1
Wessels, IF1
Aprecio, RM1
Engel, LS1
Hill, JM3
Callegan, MC2
Hyndiuk, RA2
Caldwell, DR2
Folkens, AT1
Godio, LB1
Aristimuño, B1
Nirankari, VS1
Hemady, RK1
Rodrigues, MM1
Parks, DJ1
Abrams, DA1
Sarfarazi, FA1
Katz, HR4
Maffett, M1
O'Day, DM1
Leahey, AB1
Jones, D1
Eiferman, RA2
Rosenwasser, GO1
Santos, CI1
Badrinath, SS1
Reddy, MK1
Adenis, JP1
Klauss, V1
Brancato, R1
Carones, F1
Venturi, E1
Cavallero, A1
Gesu, G1
Hill, VE1
Brownstein, S1
Jackson, WB1
Mintsioulis, G1
Kunimoto, DY1
Rao, GN1
John, D1
Daniel, E1
Goldstein, MH1
Colatrella, N1
Daniel, TE1
Madhavan, HN2
Rao, SK2
Joseph, PR1
Sulochana, KN1
Velpandian, T1
Gupta, SK1
Gupta, YK1
Agarwal, HC1
Biswas, NR1
Alexandrakis, G1
Buranapongs, W1
Prajna, NV1
George, C1
Selvaraj, S1
Lu, KL1
McDonnell, PJ1
Srinivasan, M1
Chen, KH1
Kuang, TM1
Hsu, WM1
Pinna, A1
Sechi, LA1
Zanetti, S1
Usai, D1
Delogu, G1
Cappuccinelli, P1
Carta, F1
Snyder, JP1
Nordquist, RE1
John, T1
Díaz Valle, D1
Alós Cortés, JI1
Arteaga Sánchez, A1
Toledano Fernández, N1
Poza Morales, Y1
Díaz-Valle, T1
Yolton, DP1
Stevens, RK1
Holland, GN1
Paschal, JF1
Phinney, RB1
Berlin, OG1
Bruckner, DA1
Insler, MS2
Snyder, ME1
Fish, LA1
Silbernagel, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Swiss PACK-CXL (Photoactivated Chromophore for Infectious Keratitis Cross-linking) Multicenter Trial for the Treatment of Infectious Keratitis[NCT02717871]Phase 335 participants (Actual)Interventional2016-03-31Completed
Contribution of Fast Molecular Bacterial Identification by Real-time PCR in Managing of Postoperative Acute Endophthalmitis[NCT02850653]150 participants (Anticipated)Interventional2007-11-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for ciprofloxacin and Corneal Ulcer

ArticleYear
Topical antibiotics for the management of bacterial keratitis: an evidence-based review of high quality randomised controlled trials.
    The British journal of ophthalmology, 2014, Volume: 98, Issue:11

    Topics: Administration, Topical; Anti-Bacterial Agents; Ciprofloxacin; Corneal Ulcer; Eye Infections, Bacter

2014
Infectious keratitis after photorefractive keratectomy.
    Ophthalmology, 2003, Volume: 110, Issue:4

    Topics: Adult; Ciprofloxacin; Corneal Ulcer; Cross Infection; Drug Therapy, Combination; Eye Infections, Bac

2003
Microbial keratitis and vision loss with contact lenses.
    Eye & contact lens, 2003, Volume: 29, Issue:1 Suppl

    Topics: Adult; Alcaligenes; Anti-Infective Agents; Ciprofloxacin; Contact Lenses, Extended-Wear; Corneal Ulc

2003
Rapid diagnosis and treatment of mycobacterial keratitis after laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:5

    Topics: Amikacin; Bacteriological Techniques; Ciprofloxacin; Clarithromycin; Corneal Ulcer; Diagnostic Techn

2003
New antibacterial drugs for topical ophthalmic use.
    Optometry clinics : the official publication of the Prentice Society, 1992, Volume: 2, Issue:4

    Topics: Ciprofloxacin; Conjunctivitis, Bacterial; Corneal Ulcer; Drug Therapy, Combination; Eye Infections,

1992

Trials

10 trials available for ciprofloxacin and Corneal Ulcer

ArticleYear
Evaluation of delaying effects of different short-term dosage regimens of topical ciprofloxacin on corneal ulcer healing in an avian model.
    Veterinary medicine and science, 2023, Volume: 9, Issue:2

    Topics: Animals; Ciprofloxacin; Cornea; Corneal Ulcer; Matrix Metalloproteinase 9; Ulcer

2023
Efficacy of Honey-based Ophthalmic Formulation in Patients with Corneal Ulcer: A Randomized Clinical Trial.
    Current drug discovery technologies, 2021, Volume: 18, Issue:3

    Topics: Adult; Apitherapy; Ciprofloxacin; Corneal Ulcer; Eye Foreign Bodies; Female; Honey; Humans; Male; Mi

2021
Influence of fluoroquinolone susceptibility on the therapeutic response of fluoroquinolone-treated bacterial keratitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:9

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Cornea; Corneal Ulcer; Drug Resistance, Bacterial; E

2003
Comparison of topical lomefloxacin 0.3 per cent versus topical ciprofloxacin 0.3 per cent for the treatment of presumed bacterial corneal ulcers.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87, Issue:3

    Topics: Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Chi-Square Distribution; Child; C

2004
Ocular bioerodible minitablets as strategy for the management of microbial keratitis.
    Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:9

    Topics: Absorbable Implants; Administration, Topical; Adult; Anti-Infective Agents; Chromatography, High Pre

2004
Comparison of topical gatifloxacin 0.3% and ciprofloxacin 0.3% for the treatment of bacterial keratitis.
    American journal of ophthalmology, 2006, Volume: 141, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Bacteria; Child; Ciprofloxacin;

2006
0.3% ciprofloxacin ophthalmic ointment in the treatment of bacterial keratitis. The Ciprofloxacin Ointment/Bacterial Keratitis Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:9

    Topics: Administration, Topical; Bacteria; Ciprofloxacin; Cornea; Corneal Ulcer; Drug Administration Schedul

1993
Comparison of ciprofloxacin ophthalmic solution 0.3% to fortified tobramycin-cefazolin in treating bacterial corneal ulcers. Ciprofloxacin Bacterial Keratitis Study Group.
    Ophthalmology, 1996, Volume: 103, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria;

1996
Topical ciprofloxacin for bacterial corneal ulcer.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2000, Volume: 83, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Cipro

2000
Bacteriologic and clinical efficacy of ofloxacin 0.3% versus ciprofloxacin 0.3% ophthalmic solutions in the treatment of patients with culture-positive bacterial keratitis.
    Cornea, 2001, Volume: 20, Issue:2

    Topics: Adult; Anti-Infective Agents; Bacteria; Ciprofloxacin; Corneal Ulcer; Double-Blind Method; Drug Admi

2001

Other Studies

61 other studies available for ciprofloxacin and Corneal Ulcer

ArticleYear
Ciprofloxacin Corneal Deposits With Complete Dissipation After Switching to Moxifloxacin.
    JAMA ophthalmology, 2020, 03-01, Volume: 138, Issue:3

    Topics: Administration, Ophthalmic; Aged; Anti-Bacterial Agents; Chemical Precipitation; Ciprofloxacin; Corn

2020
Bacterial keratitis due to Moraxella nonliquefaciens.
    Archivos de la Sociedad Espanola de Oftalmologia, 2020, Volume: 95, Issue:7

    Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftazidime; Ciprofloxac

2020
[Corneal ulcer secondary to Pasteurella multocida and Klebsiella oxytoca in a 79-year-old patient with dysthyroid orbitopathy].
    Journal francais d'ophtalmologie, 2020, Volume: 43, Issue:7

    Topics: Aged; Amnion; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Coinfection; Combined Modality Ther

2020
PVA/anionic collagen membranes as drug carriers of ciprofloxacin hydrochloride with sustained antibacterial activity and potential use in the treatment of ulcerative keratitis.
    Journal of biomaterials applications, 2020, Volume: 35, Issue:3

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Ciprofloxacin; Collagen; Contact Lenses; Cornea; Cor

2020
Clinical Features, Antibiotic Susceptibility Profile, and Outcomes of Infectious Keratitis Caused by Stenotrophomonas maltophilia.
    Cornea, 2018, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Corneal

2018
First two cases of Exserohilum rostratum keratitis in Australia.
    Clinical & experimental ophthalmology, 2019, Volume: 47, Issue:5

    Topics: Adult; Antifungal Agents; Ascomycota; Australia; Ciprofloxacin; Corneal Ulcer; Drug Therapy, Combina

2019
Corneal melt secondary to eosinophilic granulomatosis with polyangiitis.
    BMJ case reports, 2019, Jun-21, Volume: 12, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Ciprofloxacin; Corneal Perforat

2019
Glycyrrhizin Use for Multi-Drug Resistant Pseudomonas aeruginosa: In Vitro and In Vivo Studies.
    Investigative ophthalmology & visual science, 2019, 07-01, Volume: 60, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Corneal Ulcer; Drug Resista

2019
Spectrum of bacterial keratitis at a tertiary eye care centre in India.
    BioMed research international, 2013, Volume: 2013

    Topics: Aza Compounds; Ciprofloxacin; Corneal Ulcer; Fluoroquinolones; Gatifloxacin; Gram-Positive Bacteria;

2013
Microbial analyses of contact lens-associated microbial keratitis.
    Optometry and vision science : official publication of the American Academy of Optometry, 2014, Volume: 91, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Bacteria; Cefazolin; Ciprofloxacin; Contact Lenses; Corneal Ulcer; Dru

2014
Microbial keratitis in los angeles: the doheny eye institute and the los angeles county hospital experience.
    Ophthalmology, 2015, Volume: 122, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Child; Ciprofloxacin; C

2015
Extensively and pan-drug resistant Pseudomonas aeruginosa keratitis: clinical features, risk factors, and outcome.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016, Volume: 254, Issue:2

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Colistin; Corneal Ulcer; Drug Resistance, Multiple, Bacterial;

2016
Recurrence of peripheral ulcerative keratitis on the corneoscleral button in a young man treated successfully with oral corticosteroids.
    Cornea, 2008, Volume: 27, Issue:7

    Topics: Administration, Oral; Adult; Amnion; Anti-Infective Agents; Ciprofloxacin; Corneal Transplantation;

2008
Nona-D-arginine therapy for Pseudomonas aeruginosa keratitis.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:1

    Topics: Animals; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Ulcer; Disease Models, Animal; Drug

2009
[Bacterial corneal ulcer treated with intrastromal antibiotic. Experimental model in vivo].
    Archivos de la Sociedad Espanola de Oftalmologia, 2009, Volume: 84, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Cornea;

2009
Prompt diagnosis and treatment of microbial keratitis in a daily wear lens.
    Optometry and vision science : official publication of the American Academy of Optometry, 2009, Volume: 86, Issue:7

    Topics: Administration, Topical; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Contact Lenses;

2009
Topical levofloxacin 1.5% overcomes in vitro resistance in rabbit keratitis models.
    Acta ophthalmologica, 2010, Volume: 88, Issue:4

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Colony Count, Mic

2010
Effects of photodynamic therapy on rapidly growing nontuberculous mycobacteria keratitis.
    Investigative ophthalmology & visual science, 2011, Jan-05, Volume: 52, Issue:1

    Topics: Amikacin; Animals; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Colony Count, Microbial; Cor

2011
[Ornithinimicrobium pekingense ocular infection].
    Medecine et maladies infectieuses, 2011, Volume: 41, Issue:6

    Topics: Actinomycetales; Actinomycetales Infections; Aged; Cataract; Ciprofloxacin; Corneal Edema; Corneal U

2011
Antibiotic resistance in microbial keratitis: ten-year experience of corneal scrapes in the United Kingdom.
    Ophthalmology, 2011, Volume: 118, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Bacteriological Techniques; Cefurox

2011
Pneumococcal keratitis: a clinical profile.
    Clinical & experimental ophthalmology, 2003, Volume: 31, Issue:1

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cornea; Corneal Ulcer; Dacryocystitis; Dacryocystorhino

2003
Gatifloxacin and moxifloxacin: an in vitro susceptibility comparison to levofloxacin, ciprofloxacin, and ofloxacin using bacterial keratitis isolates.
    American journal of ophthalmology, 2003, Volume: 136, Issue:3

    Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Bacte

2003
Pseudomonas keratitis associated with continuous wear silicone-hydrogel soft contact lens: a case report.
    Eye & contact lens, 2003, Volume: 29, Issue:4

    Topics: Adult; Cefazolin; Ciprofloxacin; Contact Lenses, Extended-Wear; Corneal Ulcer; Drug Therapy, Combina

2003
Treatment of experimental bacterial keratitis with topical trovafloxacin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:1

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Biological Availability; Ciprofloxacin; Col

2004
Trimethoprim-sulphamethoxazole therapy in Nocardia keratitis.
    Clinical & experimental ophthalmology, 2004, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Child; Ciprofloxacin; Corneal Ulcer; Eye Infections,

2004
Comparative efficacy of topical gatifloxacin with ciprofloxacin, amikacin, and clarithromycin in the treatment of experimental Mycobacterium chelonae keratitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2004, Volume: 122, Issue:8

    Topics: Administration, Topical; Amikacin; Animals; Anti-Bacterial Agents; Ciprofloxacin; Clarithromycin; Co

2004
Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated with Pseudomonas aeruginosa-induced ulcerative keratitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2005, Volume: 21, Issue:1

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Cornea; Corneal Ulcer; Disea

2005
Mycobacterium chelonae keratitis: elucidation of diagnosis through evaluation of smears of fluid from patient's contact lens care system.
    Cornea, 2005, Volume: 24, Issue:3

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Contact Lens Solutions; Contact Lenses; Corne

2005
Posterior scleritis secondary to Pseudomonas aeruginosa keratitis.
    Cornea, 2005, Volume: 24, Issue:7

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Disease Progression; Eye Enucleation; Eye Infec

2005
Effectiveness of fluoroquinolones against Mycobacterium abscessus in vivo.
    Current eye research, 2006, Volume: 31, Issue:1

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Colony Count,

2006
Staphylococcus aureus ulcer associated with continuous wear of silicone hydrogel contact lenses.
    Eye & contact lens, 2006, Volume: 32, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Contact Lenses, Extended-Wear; Corneal Ulcer

2006
Pseudomonas keratitis after laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Cefazolin; Cephalosporin Resistance; Ciprofloxacin; Corneal Ulcer; Dru

2006
Zymar (Gatifloxacin 0.3%) shows excellent Gram-negative activity against Serratia marcescens and Pseudomonas aeruginosa in a New Zealand White rabbit keratitis model.
    Cornea, 2007, Volume: 26, Issue:5

    Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colony Count, Microbial; Corneal Ulcer; Disease Model

2007
Microbial keratitis in a case of lamellar ichthyosis.
    International ophthalmology, 2008, Volume: 28, Issue:5

    Topics: Anti-Bacterial Agents; Cefazolin; Child; Ciprofloxacin; Corneal Ulcer; Drug Therapy, Combination; Ec

2008
Experience of Comamonas acidovorans keratitis with delayed onset and treatment response in immunocompromised cornea.
    Korean journal of ophthalmology : KJO, 2008, Volume: 22, Issue:1

    Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Corneal Ulcer; Delftia acidovorans; Dru

2008
Comparison of topical ciprofloxacin to conventional antibiotic therapy in the treatment of experimental Pseudomonas aeruginosa keratitis.
    Cornea, 1994, Volume: 13, Issue:6

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Ciprofloxacin; Cornea; Corneal Ulcer; Disea

1994
Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis.
    Current eye research, 1993, Volume: 12, Issue:5

    Topics: Animals; Aqueous Humor; Ciprofloxacin; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combinat

1993
Spontaneous ulcerative keratitis in immunocompromised patients.
    American journal of ophthalmology, 1993, Feb-15, Volume: 115, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Administration, Topical; Adult; Amikacin; Amphotericin B; Candid

1993
Comparison of topical ciprofloxacin to conventional antibiotic therapy in the treatment of ulcerative keratitis.
    American journal of ophthalmology, 1993, Apr-15, Volume: 115, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefazolin; Ciprofloxacin; Corneal Ulcer; Drug

1993
Ciprofloxacin-resistant bacterial keratitis.
    American journal of ophthalmology, 1993, Apr-15, Volume: 115, Issue:4

    Topics: Aged; Ciprofloxacin; Cornea; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Bacterial; H

1993
Haemophilus influenzae central corneal ulcer associated with cosmetic lens wear.
    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 1996, Volume: 22, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Contact Lenses; Cornea; Corneal Ulcer; Drug Therapy, Co

1996
Mycobacterium chelonae keratitis after excimer laser photorefractive keratectomy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:10

    Topics: Adult; Amikacin; Anti-Bacterial Agents; Ciprofloxacin; Clarithromycin; Cornea; Corneal Ulcer; Eye In

1997
Infectious keratopathy complicating photorefractive keratectomy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:10

    Topics: Adult; Cefazolin; Ciprofloxacin; Cornea; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, B

1998
In vitro susceptibility of bacterial keratitis pathogens to ciprofloxacin. Emerging resistance.
    Ophthalmology, 1999, Volume: 106, Issue:1

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Colony Count, Microbial; Corneal Ulcer; Drug Resista

1999
Infectious keratitis in leprosy.
    The British journal of ophthalmology, 1999, Volume: 83, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Female; Humans; Ketoconazole; Lepr

1999
Emerging fluoroquinolone resistance in bacterial keratitis: a 5-year review.
    Ophthalmology, 1999, Volume: 106, Issue:7

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Bac

1999
Emerging fluoroquinolone resistance in bacterial keratitis: a 5-year review.
    Ophthalmology, 1999, Volume: 106, Issue:7

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Bac

1999
Emerging fluoroquinolone resistance in bacterial keratitis: a 5-year review.
    Ophthalmology, 1999, Volume: 106, Issue:7

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Bac

1999
Emerging fluoroquinolone resistance in bacterial keratitis: a 5-year review.
    Ophthalmology, 1999, Volume: 106, Issue:7

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Bac

1999
Crack eye syndrome.
    Journal of the American Optometric Association, 1999, Volume: 70, Issue:3

    Topics: Adult; Anti-Infective Agents; Ciprofloxacin; Cocaine-Related Disorders; Corneal Ulcer; Crack Cocaine

1999
Antibacterial activity of the white precipitate formed on the corneal surface after treatment with ciprofloxacin ophthalmic solution.
    Cornea, 1999, Volume: 18, Issue:5

    Topics: Adult; Anti-Infective Agents; Chemical Precipitation; Child; Child, Preschool; Chromatography, High

1999
Ciprofloxacin monotherapy and bacterial keratitis.
    Ophthalmology, 1999, Volume: 106, Issue:10

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Corynebacterium; Drug Resistance, Microbial; Ey

1999
Comparative studies on topical lomefloxacin and ciprofloxacin on ocular kinetic and experimental corneal ulcer.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1999, Volume: 15, Issue:6

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Biological Availability; Chromatography, Hi

1999
Shifting trends in bacterial keratitis in south Florida and emerging resistance to fluoroquinolones.
    Ophthalmology, 2000, Volume: 107, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cornea; Corneal Ulcer; Drug R

2000
Serratia Marcescens corneal ulcer as a complication of orthokeratology.
    American journal of ophthalmology, 2001, Volume: 132, Issue:2

    Topics: Anti-Infective Agents; Astigmatism; Child; Ciprofloxacin; Contact Lenses; Cornea; Corneal Ulcer; Eye

2001
Bacillus cereus keratitis associated with contact lens wear.
    Ophthalmology, 2001, Volume: 108, Issue:10

    Topics: Bacillaceae Infections; Bacillus cereus; Ciprofloxacin; Conjunctiva; Contact Lens Solutions; Contact

2001
Ciprofloxacin microprecipitates and macroprecipitates in the human corneal epithelium.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:10

    Topics: Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Chemical Precipitation; Chromatography, High Pr

2001
Scanning electron microscopic study of a Ciloxan bottle blocked by ciprofloxacin crystals.
    Eye (London, England), 2001, Volume: 15, Issue:Pt 6

    Topics: Anti-Infective Agents; Ciprofloxacin; Corneal Ulcer; Crystallization; Humans; Instillation, Drug; Mi

2001
Ciprofloxacin precipitates in the corneal epithelium.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:6

    Topics: Anti-Infective Agents; Chemical Precipitation; Ciprofloxacin; Corneal Ulcer; Epithelium, Corneal; Hu

2002
[Pseudomonas aeruginosa corneal abscess refractory to fluoroquinolones].
    Archivos de la Sociedad Espanola de Oftalmologia, 2002, Volume: 77, Issue:7

    Topics: Abscess; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Ceftazidime; Ciprofloxacin; Contact Le

2002
Mycobacterium fortuitum keratitis. A comparison of topical ciprofloxacin and amikacin in an animal model.
    Cornea, 1992, Volume: 11, Issue:6

    Topics: Amikacin; Animals; Ciprofloxacin; Corneal Ulcer; Disease Models, Animal; Eye Infections, Bacterial;

1992
Methicillin-resistant Staphylococcus aureus keratitis in the rabbit: therapy with ciprofloxacin, vancomycin and cefazolin.
    Current eye research, 1992, Volume: 11, Issue:11

    Topics: Animals; Cefazolin; Ciprofloxacin; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combination;

1992
Ciprofloxacin-resistant bacterial keratitis.
    American journal of ophthalmology, 1992, Sep-15, Volume: 114, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Bacteria; Ciprofloxacin; Corneal Ulcer; Drug Resistance, Microbial; Eye

1992
Successful treatment of methicillin-resistant Staphylococcus aureus Keratitis with topical ciprofloxacin.
    Ophthalmology, 1991, Volume: 98, Issue:11

    Topics: Administration, Topical; Aged; Aged, 80 and over; Ciprofloxacin; Corneal Ulcer; Eye Infections, Bact

1991