Page last updated: 2024-10-25

ciprofloxacin and Cirrhosis, Liver

ciprofloxacin has been researched along with Cirrhosis, Liver in 36 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"For the treatment of spontaneous bacterial peritonitis (SBP), cefotaxime, ceftriaxone, and ciprofloxacin were used as first-line agents."9.69Response-Guided Therapy With Cefotaxime, Ceftriaxone, or Ciprofloxacin for Spontaneous Bacterial Peritonitis: A Randomized Trial: A Validation Study of 2021 AASLD Practice Guidance for SBP. ( Baik, SK; Han, KH; Heo, J; Heo, NY; Jung, YK; Kang, SH; Kim, BI; Kim, HS; Kim, MY; Kim, TH; Kim, YS; Park, JY; Park, SY; Seo, YS; Sohn, JH; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2023)
"Once weekly ciprofloxacin was as effective as daily norfloxacin for the prevention of SBP in cirrhotic patients with ascites."9.27Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( Jang, JY; Jung, YK; Kim, BI; Kim, HS; Kim, YS; Lee, YR; Park, SY; Seo, YS; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2018)
"A total of 116 cirrhotic patients with spontaneous bacterial peritonitis, were randomly given switch therapy with ciprofloxacin (61 patients) or intravenous ceftazidime (55 patients)."9.12Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost. ( Angeli, P; Antona, C; Brollo, L; Cillo, U; Craighero, R; Fasolato, S; Franchin, M; Gatta, A; Guarda, S; Merkel, C; Miola, E; Piccolo, F, 2006)
"The aim of this prospective double-blind study was to evaluate the value of long-term antibiotic prophylaxis using ciprofloxacin for the prevention of spontaneous bacterial peritonitis (SBP) in 60 cirrhotic patients with low ascitic fluid protein levels (< 15 g/L)."9.08Ciprofloxacin and long-term prevention of spontaneous bacterial peritonitis: results of a prospective controlled trial. ( Bacq, Y; Bohn, B; Cordier, L; Franza, A; Fratte, S; Kitmacher, P; Nousbaum, JB; Paris, JC; Rolachon, A; Stahl, JP, 1995)
"The pharmacokinetics of ciprofloxacin were evaluated in 11 patients (3 patients with impaired renal function) with advanced liver cirrhosis after a single oral dose of 500 mg."7.68Pharmacokinetics of ciprofloxacin in liver cirrhosis. ( Borner, K; Hopfenmüller, W; Ruhnke, M; Trautmann, M, 1990)
"For the treatment of spontaneous bacterial peritonitis (SBP), cefotaxime, ceftriaxone, and ciprofloxacin were used as first-line agents."5.69Response-Guided Therapy With Cefotaxime, Ceftriaxone, or Ciprofloxacin for Spontaneous Bacterial Peritonitis: A Randomized Trial: A Validation Study of 2021 AASLD Practice Guidance for SBP. ( Baik, SK; Han, KH; Heo, J; Heo, NY; Jung, YK; Kang, SH; Kim, BI; Kim, HS; Kim, MY; Kim, TH; Kim, YS; Park, JY; Park, SY; Seo, YS; Sohn, JH; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2023)
"Careful dosing and a high index of suspicion of the neurological adverse effects of ciprofloxacin including movement disorders are warranted especially in cirrhotic patients."5.35A case of hemiballism as a rare side effect of ciprofloxacin in a patient with liver cirrhosis. ( Jeong, SH; Kim, JM; Kim, JW; Kim, SH; Lee, SH, 2009)
" In all critically ill patients ciprofloxacin elimination was significantly slowed; the mean half-life was similarly prolonged to about 14 h in patients on haemofiltration and those with approximately normal renal function."5.31Pharmacokinetics of ciprofloxacin in patients with acute renal failure undergoing continuous venovenous haemofiltration: influence of concomitant liver cirrhosis. ( Bellmann, R; Bellmann-Weiler, R; Dunzendorfer, S; Egger, P; Gritsch, W; Joannidis, M; Wiedermann, ChJ, 2002)
"Once weekly ciprofloxacin was as effective as daily norfloxacin for the prevention of SBP in cirrhotic patients with ascites."5.27Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial. ( Jang, JY; Jung, YK; Kim, BI; Kim, HS; Kim, YS; Lee, YR; Park, SY; Seo, YS; Suh, SJ; Um, SH; Yim, HJ; Yim, SY, 2018)
"A total of 116 cirrhotic patients with spontaneous bacterial peritonitis, were randomly given switch therapy with ciprofloxacin (61 patients) or intravenous ceftazidime (55 patients)."5.12Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost. ( Angeli, P; Antona, C; Brollo, L; Cillo, U; Craighero, R; Fasolato, S; Franchin, M; Gatta, A; Guarda, S; Merkel, C; Miola, E; Piccolo, F, 2006)
"In cirrhotic patients with variceal bleeding and with Child-Pugh class B or C, the use of intravenous ciprofloxacin for 3 days after EVL was not only effective in the prevention of bacterial infections but also cost-effective."5.10[Prospective randomized trial of intravenous ciprofloxacin for prevention of bacterial infection in cirrhotic patients with esophageal variceal bleeding]. ( Choi, KW; Choi, MS; Hong, SN; Kim, BJ; Kim, JJ; Koh, KC; Lee, CY; Lee, JH; Lee, SY; Paik, SW; Rhee, JC; Rhee, PL; Ryu, MK, 2002)
"The aim of this prospective double-blind study was to evaluate the value of long-term antibiotic prophylaxis using ciprofloxacin for the prevention of spontaneous bacterial peritonitis (SBP) in 60 cirrhotic patients with low ascitic fluid protein levels (< 15 g/L)."5.08Ciprofloxacin and long-term prevention of spontaneous bacterial peritonitis: results of a prospective controlled trial. ( Bacq, Y; Bohn, B; Cordier, L; Franza, A; Fratte, S; Kitmacher, P; Nousbaum, JB; Paris, JC; Rolachon, A; Stahl, JP, 1995)
" The aim of this study was to investigate the efficacy of prophylactic intestinal decontamination with oral ciprofloxacin for the prevention of bacterial infections in cirrhotic patients with upper gastrointestinal bleeding."5.08The effect of ciprofloxacin in the prevention of bacterial infection in patients with cirrhosis after upper gastrointestinal bleeding. ( Chang, FY; Hou, MC; Hsieh, WJ; Hwang, SJ; Lee, FY; Lee, SD; Lin, HC, 1998)
" For primary prophylaxis, short-term antibiotic treatment (oral norfloxacin or ciprofloxacin) is indicated in cirrhotic patients (with or without ascites) admitted with gastrointestinal haemorrhage (variceal or non-variceal)."4.84[Bacterial infections in liver cirrhosis]. ( Farkas, A; Papp, M; Tornai, I; Udvardy, M, 2007)
" Fluoroquinolones (norfloxacin and ciprofloxacin), third-generation cephalosporins (G3) (ceftriaxone and cefotaxime) and trimethoprim-sulfamethoxazole (SXT) are recommended for preventing infections in patients with cirrhosis or liver failure."4.12Evaluation of the current guidelines for antibacterial therapy strategies in patients with cirrhosis or liver failure. ( Dong, Y; Du, Q; Han, R; Shi, L; Sun, D; Teng, M; Wang, T; Wang, Y; Zhang, T; Zhang, Y; Zheng, G, 2022)
"In cirrhotic rats, ciprofloxacin suppressed endotoxemia and the hepatic endocannabinoid system thus ameliorating hyperdynamic circulation and decreased intrahepatic resistance by preventing hepatic fibrogenesis and endothelial dysfunction."3.77The relationship between endotoxemia and hepatic endocannabinoids in cirrhotic rats with portal hypertension. ( Huang, CM; Huang, YT; Lee, FY; Lee, SD; Lin, HC; Liu, TT; Tsai, TH; Yang, YY, 2011)
"The pharmacokinetics of ciprofloxacin were evaluated in 11 patients (3 patients with impaired renal function) with advanced liver cirrhosis after a single oral dose of 500 mg."3.68Pharmacokinetics of ciprofloxacin in liver cirrhosis. ( Borner, K; Hopfenmüller, W; Ruhnke, M; Trautmann, M, 1990)
"The pharmacokinetics of ciprofloxacin after a single 500 mg oral dose was studied in one group of healthy volunteers and in patients affected by liver cirrhosis and classified into three groups according to Child-Turcotte criteria."3.67Pharmacokinetics of ciprofloxacin in impaired liver function. ( Barba, D; Esposito, S; Miniero, M; Sagnelli, E, 1989)
"Ofloxacin kinetics were influenced by renal dysfunction encountered in patients with ascites."2.38Pharmacokinetics of fluoroquinolones in hepatic failure. ( Gaillot, J; Montay, G, 1990)
"Careful dosing and a high index of suspicion of the neurological adverse effects of ciprofloxacin including movement disorders are warranted especially in cirrhotic patients."1.35A case of hemiballism as a rare side effect of ciprofloxacin in a patient with liver cirrhosis. ( Jeong, SH; Kim, JM; Kim, JW; Kim, SH; Lee, SH, 2009)
" In all critically ill patients ciprofloxacin elimination was significantly slowed; the mean half-life was similarly prolonged to about 14 h in patients on haemofiltration and those with approximately normal renal function."1.31Pharmacokinetics of ciprofloxacin in patients with acute renal failure undergoing continuous venovenous haemofiltration: influence of concomitant liver cirrhosis. ( Bellmann, R; Bellmann-Weiler, R; Dunzendorfer, S; Egger, P; Gritsch, W; Joannidis, M; Wiedermann, ChJ, 2002)
"A 73-year-old woman with liver cirrhosis who developed H."1.30Haemophilus aphrophilus bacteraemia complicated with vertebral osteomyelitis and spinal epidural abscess in a patient with liver cirrhosis. ( Chang, SC; Chen, YC; Fang, CT; Hsieh, WC; Hsueh, PR; Hung, CC; Luh, KT, 1997)
"Ciprofloxacin was given orally at the starting dose of 250 mg every 12 hours for 7 days followed by a single dose of 250 mg/day from day 7 to day 14 and 125 mg/day for the next 3 weeks."1.30Efficacy of oral ciprofloxacin as selective intestinal decontaminant in cirrhosis. ( Borzio, M; Fragiacomo, L; Galvagno, D; Piantoni, L; Salerno, F; Saudelli, M, 1997)
"In order to develop a population pharmacokinetic model for ciprofloxacin after single oral dosing in patients with liver impairments, a retrospective population analysis of already published data was undertaken."1.30Population pharmacokinetics of ciprofloxacin in patients with liver impairments analyzed by NPEM2 algorithm--a retrospective study. ( Atanasova, I; Dimitrova, V; Terziivanov, D, 1998)
"Ciprofloxacin is an effective drug for initial treatment of SBP/CNNA."1.29Frequency, microbial spectrum and outcome of spontaneous bacterial peritonitis in north India. ( Ayyagari, A; Ghoshal, UC; Naik, SR; Puri, AS; Puri, J; Saraswat, VA; Sharma, BC, 1996)
" The pharmacokinetic parameters for ciprofloxacin were not significantly altered in cirrhotic patients."1.28The effect of cirrhosis on the steady-state pharmacokinetics of oral ciprofloxacin. ( Frost, RW; Krol, G; Lasseter, KC; Lettieri, JT; Shamblen, EC, 1989)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.56)18.7374
1990's15 (41.67)18.2507
2000's6 (16.67)29.6817
2010's11 (30.56)24.3611
2020's2 (5.56)2.80

Authors

AuthorsStudies
Dong, Y2
Sun, D1
Wang, Y1
Du, Q1
Zhang, Y1
Han, R1
Teng, M1
Zhang, T1
Shi, L1
Zheng, G1
Wang, T1
Yim, HJ2
Kim, TH1
Suh, SJ2
Yim, SY2
Jung, YK2
Seo, YS2
Kang, SH1
Kim, MY1
Baik, SK1
Kim, HS3
Kim, YS2
Park, SY2
Kim, BI3
Park, JY1
Heo, J1
Sohn, JH1
Heo, NY1
Han, KH1
Um, SH2
Mo, S1
Bendtsen, F1
Wiese, SS1
Kimer, N1
Lee, YR1
Jang, JY1
Vinnitskaia, EV1
Drozdov, VN1
Petyrakov, AV1
Sil'vestrova, SIu1
Brezgin, AG1
Nazir, S1
Brown, K1
Shin, AK1
Donato, AA1
Lutz, P1
Nischalke, HD1
Krämer, B1
Goeser, F1
Kaczmarek, DJ1
Schlabe, S1
Parcina, M1
Nattermann, J1
Hoerauf, A1
Strassburg, CP1
Spengler, U1
Kim, SH1
Jeong, SH1
Kim, JW1
Lee, SH1
Kim, JM1
Lin, HC2
Yang, YY1
Tsai, TH1
Huang, CM1
Huang, YT1
Lee, FY2
Liu, TT1
Lee, SD2
Fukui, H1
Kim, HJ1
Park, JH1
Park, DI1
Cho, YK1
Sohn, CI1
Jeon, WK1
Kim, DJ1
Senzolo, M1
Nadal, E1
Cholongitas, E1
Burroughs, AK1
Tsui, TL1
Tsao, SM1
Liu, KS1
Chen, TY1
Wang, YL1
Teng, YH1
Lee, YT1
Reuken, PA1
Pletz, MW1
Baier, M1
Pfister, W1
Stallmach, A1
Bruns, T1
Bellmann, R1
Egger, P1
Gritsch, W1
Bellmann-Weiler, R1
Joannidis, M1
Dunzendorfer, S1
Wiedermann, ChJ1
Hong, SN1
Kim, BJ1
Lee, SY1
Lee, CY1
Ryu, MK1
Choi, MS1
Lee, JH1
Rhee, PL1
Koh, KC1
Kim, JJ1
Paik, SW1
Rhee, JC1
Choi, KW1
Angeli, P1
Guarda, S1
Fasolato, S1
Miola, E1
Craighero, R1
Piccolo, F1
Antona, C1
Brollo, L1
Franchin, M1
Cillo, U1
Merkel, C1
Gatta, A1
Wang, CY1
Chuang, YM1
Teng, LJ1
Lee, LN1
Yang, PC1
Kuo, SH1
Hsueh, PR3
Papp, M1
Farkas, A1
Udvardy, M1
Tornai, I1
Rolachon, A1
Cordier, L1
Bacq, Y1
Nousbaum, JB1
Franza, A1
Paris, JC1
Fratte, S1
Bohn, B1
Kitmacher, P1
Stahl, JP1
Chan, TY1
Chow, DP1
Ng, KC1
Pang, KW1
McBride, GA1
Castiella, A1
Yuste, R1
Gonzalez, F1
Martinez, S1
Alzate, L1
Arriola, JA1
Arenas, JI1
Wu, JJ1
Hsiue, TR1
Hsieh, WC2
Marmorale, A1
Mainguene, C1
Gavelli, A1
Huguet, C1
Puri, AS1
Puri, J1
Ghoshal, UC1
Sharma, BC1
Saraswat, VA1
Ayyagari, A1
Naik, SR1
Gerbes, AL1
Hung, CC1
Chen, YC1
Fang, CT1
Chang, SC1
Luh, KT1
Borzio, M1
Salerno, F1
Saudelli, M1
Galvagno, D1
Piantoni, L1
Fragiacomo, L1
Hsieh, WJ1
Hwang, SJ1
Hou, MC1
Chang, FY1
Terziivanov, D1
Atanasova, I1
Dimitrova, V1
Terg, R1
Llano, K1
Cobas, SM1
Brotto, C1
Barrios, A1
Levi, D1
Wasen, W1
Bartellini, MA1
Ortiz, J1
Vila, MC1
Soriano, G1
Miñana, J1
Gana, J1
Mirelis, B1
Novella, MT1
Coll, S1
Sábat, M1
Andreu, M1
Prats, G1
Solá, R1
Guarner, C1
Montay, G1
Gaillot, J1
Ruhnke, M1
Trautmann, M1
Borner, K1
Hopfenmüller, W1
Esposito, S1
Miniero, M1
Barba, D1
Sagnelli, E1
Frost, RW1
Lettieri, JT1
Krol, G1
Shamblen, EC1
Lasseter, KC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Terlipressin Given As I.V. Boluses Vs Terlipressin Given As Continuous Intravenous Infusion In Patients With Cirrhosis And Type 1 Hepatorenal Syndrome (Hrs): Preliminary Results Of A Randomized Controlled Clinical Study.[NCT00742690]Phase 2/Phase 370 participants (Anticipated)Interventional2005-05-31Recruiting
Daptomycin + Meropenem Versus Ceftazidime in the Treatment of Nosocomial Spontaneous Bacterial Peritonitis: an Open, Randomized, Controlled Clinical Trial[NCT01455246]Phase 2/Phase 332 participants (Actual)Interventional2010-10-31Terminated (stopped due to Decision of independent monitoring committee after interim analysis: Risk of failure significantly higher in ceftazidime group.)
Comparison of Daily Norfloxacin Versus Weekly Ciprofloxacin for the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients[NCT01542801]Phase 4124 participants (Actual)Interventional2011-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for ciprofloxacin and Cirrhosis, Liver

ArticleYear
[Spontaneous bacterial peritonitis in liver cirrhosis: optimization issues of prevention and treatment].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2012, Issue:6

    Topics: Anti-Infective Agents; Ascitic Fluid; Bacterial Infections; Ciprofloxacin; Female; Humans; Liver Cir

2012
[Bacterial infections in liver cirrhosis].
    Orvosi hetilap, 2007, Mar-04, Volume: 148, Issue:9

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ascites;

2007
Pharmacokinetics of fluoroquinolones in hepatic failure.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl B

    Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Chronic Disease; Ciprofloxacin; Female; Ha

1990

Trials

9 trials available for ciprofloxacin and Cirrhosis, Liver

ArticleYear
Response-Guided Therapy With Cefotaxime, Ceftriaxone, or Ciprofloxacin for Spontaneous Bacterial Peritonitis: A Randomized Trial: A Validation Study of 2021 AASLD Practice Guidance for SBP.
    The American journal of gastroenterology, 2023, 04-01, Volume: 118, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Ascites; Bacterial Infections; Cefotaxime; Ceftriaxo

2023
Daily Norfloxacin vs. Weekly Ciprofloxacin to Prevent Spontaneous Bacterial Peritonitis: A Randomized Controlled Trial.
    The American journal of gastroenterology, 2018, Volume: 113, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Ascites; Bacterial Infections; Ciprofloxacin; Disease-Free Survi

2018
Increased intestinal permeability as a predictor of bacterial infections in patients with decompensated liver cirrhosis and hemorrhage.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:3

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Bacterial Infections; Bacterial Translocation; C

2011
[Prospective randomized trial of intravenous ciprofloxacin for prevention of bacterial infection in cirrhotic patients with esophageal variceal bleeding].
    Taehan Kan Hakhoe chi = The Korean journal of hepatology, 2002, Volume: 8, Issue:3

    Topics: Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciprofloxacin; End

2002
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Switch therapy with ciprofloxacin vs. intravenous ceftazidime in the treatment of spontaneous bacterial peritonitis in patients with cirrhosis: similar efficacy at lower cost.
    Alimentary pharmacology & therapeutics, 2006, Jan-01, Volume: 23, Issue:1

    Topics: Administration, Oral; Albumins; Anti-Bacterial Agents; Antihypertensive Agents; Ceftazidime; Ciprofl

2006
Ciprofloxacin and long-term prevention of spontaneous bacterial peritonitis: results of a prospective controlled trial.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:4 Pt 1

    Topics: Adult; Aged; Anti-Infective Agents; Antibiotic Prophylaxis; Ascites; Bacterial Infections; Ciproflox

1995
[Antibiotic prophylaxis after gastrointestinal hemorrhage in liver cirrhosis--for which patients, with what antibiotics?].
    Zeitschrift fur Gastroenterologie, 1997, Volume: 35, Issue:8

    Topics: Amoxicillin-Potassium Clavulanate Combination; Antibiotic Prophylaxis; Bacterial Infections; Ciprofl

1997
The effect of ciprofloxacin in the prevention of bacterial infection in patients with cirrhosis after upper gastrointestinal bleeding.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:6

    Topics: Acute Disease; Administration, Oral; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fem

1998
Effects of oral ciprofloxacin on aerobic gram-negative fecal flora in patients with cirrhosis: results of short- and long-term administration, with daily and weekly dosages.
    Journal of hepatology, 1998, Volume: 29, Issue:3

    Topics: Administration, Oral; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship,

1998

Other Studies

24 other studies available for ciprofloxacin and Cirrhosis, Liver

ArticleYear
Evaluation of the current guidelines for antibacterial therapy strategies in patients with cirrhosis or liver failure.
    BMC infectious diseases, 2022, Jan-04, Volume: 22, Issue:1

    Topics: Anti-Bacterial Agents; Cefotaxime; Ciprofloxacin; Humans; Liver Cirrhosis; Liver Failure

2022
Low ascitic fluid total protein levels is not associated to the development of spontaneous bacterial peritonitis in a cohort of 274 patients with cirrhosis.
    Scandinavian journal of gastroenterology, 2018, Volume: 53, Issue:2

    Topics: Anti-Bacterial Agents; Ascites; Ascitic Fluid; Bacterial Infections; Biomarkers; Ciprofloxacin; Denm

2018
Vibrio vulnificus infection and liver cirrhosis: a potentially lethal combination.
    BMJ case reports, 2016, May-05, Volume: 2016

    Topics: Adult; Animals; Ciprofloxacin; Debridement; Doxycycline; Early Diagnosis; Humans; Liver Cirrhosis; M

2016
Antibiotic resistance in healthcare-related and nosocomial spontaneous bacterial peritonitis.
    European journal of clinical investigation, 2017, Volume: 47, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Ceftriaxone; Ciprofloxacin; Cross Infection; Drug

2017
A case of hemiballism as a rare side effect of ciprofloxacin in a patient with liver cirrhosis.
    Chemotherapy, 2009, Volume: 55, Issue:4

    Topics: Ciprofloxacin; Dyskinesia, Drug-Induced; Female; Hepatitis B; Humans; Liver Cirrhosis; Magnetic Reso

2009
The relationship between endotoxemia and hepatic endocannabinoids in cirrhotic rats with portal hypertension.
    Journal of hepatology, 2011, Volume: 54, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cannabinoid Receptor Modulators; Ciprofloxacin; Disease Models, Anim

2011
How leaky gut and endotoxemia induce bacterial infection in cirrhosis and gastrointestinal hemorrhage?
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:3

    Topics: Administration, Oral; Anti-Bacterial Agents; Bacterial Infections; Bacterial Translocation; Cephalos

2011
Is hydrophobia necessary for the hepatologist prescribing nonselective beta-blockers in cirrhosis?
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Anti-Infective Agents; Ciprofloxacin; Dose-Response Relationship,

2011
Comamonas testosteroni infection in Taiwan: Reported two cases and literature review.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2011, Volume: 44, Issue:1

    Topics: Aged; Alcoholism; Anti-Bacterial Agents; Bacteremia; Carcinoma, Hepatocellular; Cellulitis; Cephalos

2011
Emergence of spontaneous bacterial peritonitis due to enterococci - risk factors and outcome in a 12-year retrospective study.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:10

    Topics: Aged; Analysis of Variance; Anti-Infective Agents; Ascitic Fluid; Cephalosporins; Ciprofloxacin; Ent

2012
Pharmacokinetics of ciprofloxacin in patients with acute renal failure undergoing continuous venovenous haemofiltration: influence of concomitant liver cirrhosis.
    Acta medica Austriaca, 2002, Volume: 29, Issue:3

    Topics: Acute Kidney Injury; Anti-Infective Agents; Area Under Curve; Chromatography, High Pressure Liquid;

2002
Bacteraemic pneumonia caused by Neisseria lactamica with reduced susceptibility to penicillin and ciprofloxacin in an adult with liver cirrhosis.
    Journal of medical microbiology, 2006, Volume: 55, Issue:Pt 8

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Base Sequence; Ceftriaxone; Ciprofl

2006
Vibrio vulnificus septicemia in a patient with liver cirrhosis.
    The Southeast Asian journal of tropical medicine and public health, 1994, Volume: 25, Issue:1

    Topics: Animals; Bacteremia; Brachyura; Ceftazidime; Ciprofloxacin; Drug Therapy, Combination; Female; Hepat

1994
[Infection of ascitic fluid caused by Campylobacter jejuni in a patient with liver cirrhosis. A new case with an atypical presentation].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:8-9

    Topics: Ascitic Fluid; Campylobacter Infections; Campylobacter jejuni; Ciprofloxacin; Humans; Liver Cirrhosi

1994
Bacteremic necrotizing fasciitis due to Flavobacterium odoratum.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 21, Issue:5

    Topics: Aged; Anti-Infective Agents; Bacteremia; Ciprofloxacin; Drug Resistance, Multiple; Fasciitis, Necrot

1995
[Pure angiocholitic form of congenital hepatic fibrosis].
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:2

    Topics: Anti-Infective Agents; Cholangitis; Ciprofloxacin; Combined Modality Therapy; Female; Humans; Liver

1996
Frequency, microbial spectrum and outcome of spontaneous bacterial peritonitis in north India.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1996, Volume: 15, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Cohort Stu

1996
Haemophilus aphrophilus bacteraemia complicated with vertebral osteomyelitis and spinal epidural abscess in a patient with liver cirrhosis.
    The Journal of infection, 1997, Volume: 35, Issue:3

    Topics: Abscess; Aged; Bacteremia; Cefotaxime; Ciprofloxacin; Epidural Space; Female; Haemophilus; Haemophil

1997
Efficacy of oral ciprofloxacin as selective intestinal decontaminant in cirrhosis.
    Italian journal of gastroenterology and hepatology, 1997, Volume: 29, Issue:3

    Topics: Administration, Oral; Anti-Infective Agents; Antibiotic Prophylaxis; Bacterial Infections; Ciproflox

1997
Population pharmacokinetics of ciprofloxacin in patients with liver impairments analyzed by NPEM2 algorithm--a retrospective study.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:7

    Topics: Administration, Oral; Algorithms; Anti-Infective Agents; Bayes Theorem; Bias; Ciprofloxacin; Female;

1998
Infections caused by Escherichia coli resistant to norfloxacin in hospitalized cirrhotic patients.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:4

    Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ciprofloxacin; Drug Resi

1999
Pharmacokinetics of ciprofloxacin in liver cirrhosis.
    Chemotherapy, 1990, Volume: 36, Issue:6

    Topics: Administration, Oral; Adult; Ciprofloxacin; Female; Humans; Kidney Diseases; Liver Cirrhosis; Male;

1990
Pharmacokinetics of ciprofloxacin in impaired liver function.
    International journal of clinical pharmacology research, 1989, Volume: 9, Issue:1

    Topics: Adult; Ciprofloxacin; Female; Humans; Liver; Liver Cirrhosis; Male; Middle Aged

1989
The effect of cirrhosis on the steady-state pharmacokinetics of oral ciprofloxacin.
    Clinical pharmacology and therapeutics, 1989, Volume: 45, Issue:6

    Topics: Administration, Oral; Aged; Anti-Infective Agents; Biotransformation; Chromatography, High Pressure

1989