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ciprofloxacin and Cholestasis

ciprofloxacin has been researched along with Cholestasis in 19 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Research Excerpts

ExcerptRelevanceReference
"To determine the role of ciprofloxacin in reducing cholangitis in cholestatic patients with adequate biliary drainage after endoscopic retrograde cholangiopancreatography (ERCP)."9.12Role of ciprofloxacin in patients with cholestasis after endoscopic retrograde cholangiopancreatography. ( Chantawibul, S; Leelawat, K; Panpimanmas, S; Prajanphanit, P; Ratanachu-ek, T; Subwongcharoen, S; Wannaprasert, J, 2007)
"The aim of this study was to evaluate the effect of bile duct obstruction on biliary secretion of ciprofloxacin and to look for useful parameters to guide clinical use of antibiotics in patients with acute cholangitis."7.70The effects of bile duct obstruction on the biliary secretion of ciprofloxacin in piglets. ( Chen, CY; Lin, XZ; Shiesh, SC; Wu, MC, 1999)
"This study investigates the potential benefits of antibiotics and N-acetylcysteine (NAC), a mucolytic agent, in patients who are candidates for endoscopic retrograde cholangiopancreatography (ERCP) due to partial bile duct obstruction."5.14Potential benefits of combined N-acetylcysteine and ciprofloxacin therapy in partial biliary obstruction. ( Akkiz, H; Cosar, A; Kece, C; Ozdil, B; Sandikci, M, 2010)
"To determine the role of ciprofloxacin in reducing cholangitis in cholestatic patients with adequate biliary drainage after endoscopic retrograde cholangiopancreatography (ERCP)."5.12Role of ciprofloxacin in patients with cholestasis after endoscopic retrograde cholangiopancreatography. ( Chantawibul, S; Leelawat, K; Panpimanmas, S; Prajanphanit, P; Ratanachu-ek, T; Subwongcharoen, S; Wannaprasert, J, 2007)
" In each follow-up visit, clinical symptoms of cholangitis were documented and blood samples taken for blood counts, serum levels of bilirubin, and alkaline phosphatase."5.09Long-term ciprofloxacin treatment for the prevention of biliary stent blockage: a prospective randomized study. ( Chung, SC; Ismael, A; Lai, CW; Sollano, JD; Sung, JJ; Tumala, I; Yung, MY, 1999)
"The aim of this study was to evaluate the effect of bile duct obstruction on biliary secretion of ciprofloxacin and to look for useful parameters to guide clinical use of antibiotics in patients with acute cholangitis."3.70The effects of bile duct obstruction on the biliary secretion of ciprofloxacin in piglets. ( Chen, CY; Lin, XZ; Shiesh, SC; Wu, MC, 1999)
"Cholangitis is a frequent complication of biliary stents."1.31Microbiology of bile in patients with cholangitis or cholestasis with and without plastic biliary endoprosthesis. ( Esber, E; Fogel, EL; Kalayci, C; Lehman, GA; Rerknimitr, R; Sherman, S, 2002)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's11 (57.89)18.2507
2000's5 (26.32)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wanek, T1
Halilbasic, E1
Visentin, M1
Mairinger, S1
Römermann, K1
Stieger, B1
Kuntner, C1
Müller, M1
Langer, O1
Trauner, M1
Dichiara, AJ1
Atkinson, M1
Goodman, Z1
Sherman, KE1
Ozdil, B1
Kece, C1
Cosar, A1
Akkiz, H1
Sandikci, M1
Bataille, L1
Rahier, J1
Geubel, A1
Rerknimitr, R1
Fogel, EL1
Kalayci, C1
Esber, E1
Lehman, GA1
Sherman, S1
Ratanachu-ek, T1
Prajanphanit, P1
Leelawat, K1
Chantawibul, S1
Panpimanmas, S1
Subwongcharoen, S1
Wannaprasert, J1
Dhalluin-Venier, V1
Bazin, C1
Massias, L1
Farah, RB1
Boytchev, I1
Fritsch, J1
Choury, AD1
Prat, F1
Buffet, C1
Furlan, V1
Pelletier, G1
Sherman, O1
Beizer, JL1
Aggarwal, A1
Gurka, J1
Mohandas, KM1
Kelker, R1
Hautekeete, ML1
Kockx, MM1
Naegels, S1
Holvoet, JK1
Hubens, H1
Kloppel, G1
van den Hazel, SJ1
de Vries, XH1
Speelman, P1
Dankert, J1
Tytgat, GN1
Huibregtse, K1
van Leeuwen, DJ1
Demediuk, B1
Speer, AG1
Hellyar, A1
Labowitz, JK1
Silverman, WB1
Mani, V1
Cartwright, K1
Dooley, J1
Swarbrick, E1
Fairclough, P1
Oakley, C1
Luman, W1
Ghosh, S1
Palmer, KR1
Chen, CY1
Shiesh, SC1
Wu, MC1
Lin, XZ1
Sung, JJ1
Sollano, JD1
Lai, CW1
Ismael, A1
Yung, MY1
Tumala, I1
Chung, SC1
Ball, CS1
Manson, JM1
Reid, F1
Tweedle, DE1

Reviews

1 review available for ciprofloxacin and Cholestasis

ArticleYear
Ciprofloxacin-induced acute cholestatic liver injury and associated renal failure. Case report and review.
    Minerva gastroenterologica e dietologica, 2008, Volume: 54, Issue:3

    Topics: Acute Kidney Injury; Aged; Anti-Infective Agents; Cellulitis; Cholestasis; Ciprofloxacin; Humans; Ja

2008

Trials

6 trials available for ciprofloxacin and Cholestasis

ArticleYear
Potential benefits of combined N-acetylcysteine and ciprofloxacin therapy in partial biliary obstruction.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:12

    Topics: Acetylcysteine; Aged; Anti-Infective Agents; Bile Ducts; Bilirubin; C-Reactive Protein; Cholangiopan

2010
Role of ciprofloxacin in patients with cholestasis after endoscopic retrograde cholangiopancreatography.
    World journal of gastroenterology, 2007, Jan-14, Volume: 13, Issue:2

    Topics: Adult; Aged; Anti-Infective Agents; Bacteria; Bile; Cholangiopancreatography, Endoscopic Retrograde;

2007
Effects of biliary obstruction on the penetration of ciprofloxacin and cefotaxime.
    European journal of gastroenterology & hepatology, 2008, Volume: 20, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bile; Bilirubin; Cefotaxime; Cholangiopancreatograph

2008
Biliary excretion of ciprofloxacin and piperacillin in the obstructed biliary tract.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bile; Cholestasis; Ciprofloxacin; Female; Hum

1996
A combination of ciprofloxacin and Rowachol does not prevent biliary stent occlusion.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:3 Pt 1

    Topics: Aged; Alkaline Phosphatase; Anti-Infective Agents; Bile Duct Neoplasms; Bilirubin; Cholagogues and C

1999
Long-term ciprofloxacin treatment for the prevention of biliary stent blockage: a prospective randomized study.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Anti-Infective Agents; Bile Duct Neoplasms; Bi

1999

Other Studies

12 other studies available for ciprofloxacin and Cholestasis

ArticleYear
Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice.
    Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4;

2016
Delayed and prolonged cholestatic hepatitis with ductopenia after long-term ciprofloxacin therapy for Crohn's disease.
    Journal of hepatology, 2002, Volume: 37, Issue:5

    Topics: Anti-Infective Agents; Bile Ducts; Chemical and Drug Induced Liver Injury; Cholestasis; Chronic Dise

2002
Microbiology of bile in patients with cholangitis or cholestasis with and without plastic biliary endoprosthesis.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bile; Chil

2002
Possible ciprofloxacin-induced acute cholestatic jaundice.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:10

    Topics: Acute Disease; Aged; Aged, 80 and over; Cholestasis; Ciprofloxacin; Female; Humans

1994
Probable ciprofloxacin induced cholestasis.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:5

    Topics: Adult; Anti-Infective Agents; Cholestasis; Ciprofloxacin; Humans; Male

1995
Antibiotic prophylaxis of ERCP with ciprofloxacin.
    Gastrointestinal endoscopy, 1996, Volume: 43, Issue:2 Pt 1

    Topics: Anti-Infective Agents; Antibiotic Prophylaxis; Cholangiopancreatography, Endoscopic Retrograde; Chol

1996
Cholestatic hepatitis related to quinolones: a report of two cases.
    Journal of hepatology, 1995, Volume: 23, Issue:6

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Chemical and Drug Induced Liver Injury; Cholestasis;

1995
Induced antibiotic-resistant bacteria in cholangitis with biliary stasis.
    The Australian and New Zealand journal of surgery, 1996, Volume: 66, Issue:11

    Topics: Aged; Anti-Infective Agents; Cholangitis; Cholestasis; Ciprofloxacin; Enterobacter cloacae; Enteroba

1996
Cholestatic jaundice induced by ciprofloxacin.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:1

    Topics: Anti-Infective Agents; Cholestasis; Ciprofloxacin; Humans; Liver; Male; Middle Aged

1997
Antibiotic prophylaxis in gastrointestinal endoscopy: a report by a Working Party for the British Society of Gastroenterology Endoscopy Committee.
    Endoscopy, 1997, Volume: 29, Issue:2

    Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophyla

1997
The effects of bile duct obstruction on the biliary secretion of ciprofloxacin in piglets.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:9

    Topics: Animals; Anti-Infective Agents; Bile; Bile Ducts; Cholestasis; Ciprofloxacin; Female; Male; Swine

1999
The pharmacokinetics of the biliary excretion of ciprofloxacin.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1989, Volume: 1, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bile; Biliary Tract Diseases; Cholestasis; Ciprofloxacin; Female; Hu

1989