ciprofloxacin has been researched along with Cerebrospinal Fluid Otorrhea in 9 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Cerebrospinal Fluid Otorrhea: Discharge of cerebrospinal fluid through the external auditory meatus or through the eustachian tube into the nasopharynx. This is usually associated with CRANIOCEREBRAL TRAUMA (e.g., SKULL FRACTURE involving the TEMPORAL BONE;), NEUROSURGICAL PROCEDURES; or other conditions, but may rarely occur spontaneously. (From Am J Otol 1995 Nov;16(6):765-71)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Randomized, patient-masked, parallel-group, multicenter trial of topical otic ciprofloxacin/dexamethasone versus topical ciprofloxacin alone in 201 children aged 6 months to 12 years with acute otitis media with tympanostomy tubes (AOMT) of less than or equal to 3 weeks' duration and visible otorrhea." | 9.10 | Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes. ( Anon, JB; Conroy, PJ; Dupre, SJ; Hogg, G; Krueger, KA; Moe, RD; Potts, S; Roland, PS; Stroman, DW; Wall, GM, 2003) |
| "Randomized, patient-masked, parallel-group, multicenter trial of topical otic ciprofloxacin/dexamethasone versus topical ciprofloxacin alone in 201 children aged 6 months to 12 years with acute otitis media with tympanostomy tubes (AOMT) of less than or equal to 3 weeks' duration and visible otorrhea." | 5.10 | Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes. ( Anon, JB; Conroy, PJ; Dupre, SJ; Hogg, G; Krueger, KA; Moe, RD; Potts, S; Roland, PS; Stroman, DW; Wall, GM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vaile, L | 2 |
| Williamson, T | 2 |
| Waddell, A | 2 |
| Taylor, GJ | 1 |
| Heslop, A | 1 |
| Lildholdt, T | 1 |
| Gammelgaard, N | 1 |
| Ovesen, T | 1 |
| Roland, PS | 2 |
| Anon, JB | 1 |
| Moe, RD | 1 |
| Conroy, PJ | 2 |
| Wall, GM | 2 |
| Dupre, SJ | 2 |
| Krueger, KA | 1 |
| Potts, S | 1 |
| Hogg, G | 1 |
| Stroman, DW | 1 |
| Dohar, JE | 1 |
| Lanier, BJ | 1 |
| Hekkenburg, R | 1 |
| Lane, EM | 1 |
| Potts, SL | 1 |
| Taylor, G | 1 |
| Giles, W | 1 |
| Dohar, J | 1 |
| Iverson, K | 1 |
| Cockrum, P | 1 |
| Hill, F | 1 |
| Hill, N | 1 |
| Kasemsuwan, L | 1 |
| Clongsuesuek, P | 1 |
| Zipfel, TE | 1 |
| Wood, WE | 1 |
| Street, DF | 1 |
| Wulffman, J | 1 |
| Tipirneni, A | 1 |
| Frey, C | 1 |
| Gibson, WS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does the Use of Topical Otic Drops at the Time of Tympanostomy Tube Placement Improve Outcomes When no Middle Ear Effusion is Present at the Time of Surgery[NCT03655665] | Phase 4 | 125 participants (Anticipated) | Interventional | 2019-05-16 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ciprofloxacin and Cerebrospinal Fluid Otorrhea
| Article | Year |
|---|---|
WITHDRAWN: Interventions for ear discharge associated with grommets (ventilation tubes).
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cerebrospinal Fluid Oto | 2016 |
Interventions for ear discharge associated with grommets (ventilation tubes).
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cerebrospinal Fluid Oto | 2006 |
6 trials available for ciprofloxacin and Cerebrospinal Fluid Otorrhea
| Article | Year |
|---|---|
Topical ciprofloxacin is superior to topical saline and systemic antibiotics in the treatment of tympanostomy tube otorrhea in children: the results of a randomized clinical trial.
Topics: Administration, Oral; Administration, Topical; Amoxicillin; Anti-Infective Agents; Cerebrospinal Flu | 2010 |
Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes.
Topics: Acute Disease; Administration, Topical; Cerebrospinal Fluid Otorrhea; Child; Child, Preschool; Cipro | 2003 |
Topical ciprofloxacin/dexamethasone otic suspension is superior to ofloxacin otic solution in the treatment of granulation tissue in children with acute otitis media with otorrhea through tympanostomy tubes.
Topics: Administration, Topical; Adolescent; Anti-Infective Agents; Anti-Inflammatory Agents; Cerebrospinal | 2004 |
Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Cerebrospinal Fluid | 2007 |
A double blind, prospective trial of topical ciprofloxacin versus normal saline solution in the treatment of otorrhoea.
Topics: Administration, Topical; Adult; Aged; Anti-Infective Agents; Bacteria, Aerobic; Cerebrospinal Fluid | 1997 |
The effect of topical ciprofloxacin on postoperative otorrhea after tympanostomy tube insertion.
Topics: Administration, Topical; Adolescent; Cerebrospinal Fluid Otorrhea; Child; Child, Preschool; Ciproflo | 1999 |
1 other study available for ciprofloxacin and Cerebrospinal Fluid Otorrhea
| Article | Year |
|---|---|
Ciprofloxacin (Otiprio) for tympanostomy tube insertion.
Topics: Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Cerebrospinal Fluid | 2016 |