ciprofloxacin has been researched along with Carcinoma, Transitional Cell in 9 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
Carcinoma, Transitional Cell: A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral ciprofloxacin might achieve higher concentration in urine than in serum; theoretically, this drug might act as an anticancer drug against bladder cancer cells." | 8.86 | Ciprofloxacin criteria in antimicrobial prophylaxis and bladder cancer recurrence. ( Drewa, T; Gurtowska, N; Kloskowski, T, 2010) |
| "The disruption of calcium homeostasis, mitochondrial swelling and redistribution of Bax to the mitochondrial membrane are key events in the initiation of apoptotic processes in ciprofloxacin treated bladder cancer cells." | 7.71 | Role of mitochondria in ciprofloxacin induced apoptosis in bladder cancer cells. ( Alhasan, S; Aranha, O; Kuo, TH; Sarkar, FH; Wood, DP; Zhu, L, 2002) |
| "The results of this study show that both ciprofloxacin, chosen for its use as possible radiosensitizing agent in bladder cancer patients, and hydrocortisone, chosen as an example of lypofilic endogenous compound, can be absorbed through the intestinal mucosa of a continent ileal reservoir, but to a different extent and with high interindividual variability." | 5.12 | Interindividual variability in the absorption of ciprofloxacin and hydrocortisone from continent ileal reservoir for urine. ( Corbu, C; Garbero, C; Gosmar, M; Manfredi, V; Martelli, A; Mattioli, F; Tognoni, P, 2006) |
| "Oral ciprofloxacin might achieve higher concentration in urine than in serum; theoretically, this drug might act as an anticancer drug against bladder cancer cells." | 4.86 | Ciprofloxacin criteria in antimicrobial prophylaxis and bladder cancer recurrence. ( Drewa, T; Gurtowska, N; Kloskowski, T, 2010) |
| "The disruption of calcium homeostasis, mitochondrial swelling and redistribution of Bax to the mitochondrial membrane are key events in the initiation of apoptotic processes in ciprofloxacin treated bladder cancer cells." | 3.71 | Role of mitochondria in ciprofloxacin induced apoptosis in bladder cancer cells. ( Alhasan, S; Aranha, O; Kuo, TH; Sarkar, FH; Wood, DP; Zhu, L, 2002) |
| "The recurrence rate for superficial bladder tumors treated with complete resection averages 88%." | 1.32 | Antitumor activity of common antibiotics against superficial bladder cancer. ( Kamat, AM; Lamm, DL, 2004) |
| "Ciprofloxacin and ofloxacin inhibit proliferation and DNA synthesis of these 3 human TCC lines in vitro." | 1.29 | Inhibition of human transitional cell carcinoma in vitro proliferation by fluoroquinolone antibiotics. ( Dixon, PS; Peretsman, SJ; Seay, TM, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gurtowska, N | 1 |
| Kloskowski, T | 1 |
| Drewa, T | 1 |
| Kamat, AM | 2 |
| Lamm, DL | 2 |
| Mattioli, F | 1 |
| Tognoni, P | 1 |
| Manfredi, V | 1 |
| Gosmar, M | 1 |
| Corbu, C | 1 |
| Garbero, C | 1 |
| Martelli, A | 1 |
| Seay, TM | 1 |
| Peretsman, SJ | 1 |
| Dixon, PS | 1 |
| Ebisuno, S | 1 |
| Inagaki, T | 1 |
| Kohjimoto, Y | 1 |
| Ohkawa, T | 1 |
| Beatty, JA | 1 |
| Martin, P | 1 |
| Kendall, K | 1 |
| Malik, R | 1 |
| DeHaven, JI | 1 |
| Aranha, O | 2 |
| Wood, DP | 2 |
| Sarkar, FH | 2 |
| Zhu, L | 1 |
| Alhasan, S | 1 |
| Kuo, TH | 1 |
1 review available for ciprofloxacin and Carcinoma, Transitional Cell
| Article | Year |
|---|---|
Ciprofloxacin criteria in antimicrobial prophylaxis and bladder cancer recurrence.
Topics: Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Line, Tumor; Ciprof | 2010 |
1 trial available for ciprofloxacin and Carcinoma, Transitional Cell
| Article | Year |
|---|---|
Interindividual variability in the absorption of ciprofloxacin and hydrocortisone from continent ileal reservoir for urine.
Topics: Administration, Intravesical; Aged; Analysis of Variance; Carcinoma, Transitional Cell; Ciprofloxaci | 2006 |
7 other studies available for ciprofloxacin and Carcinoma, Transitional Cell
| Article | Year |
|---|---|
Antitumor activity of common antibiotics against superficial bladder cancer.
Topics: Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Cefazolin; Cell Line, Tumor; Ciprofloxaci | 2004 |
Inhibition of human transitional cell carcinoma in vitro proliferation by fluoroquinolone antibiotics.
Topics: Anti-Infective Agents; Carcinoma, Transitional Cell; Cell Division; Ciprofloxacin; Dose-Response Rel | 1996 |
The cytotoxic effect of fleroxacin and ciprofloxacin on transitional cell carcinoma in vitro.
Topics: Animals; Anti-Infective Agents; Carcinoma, Transitional Cell; Cell Count; Cell Division; Cell Surviv | 1997 |
Haematuria in a geriatric cat.
Topics: Animals; Anti-Infective Agents; Azure Stains; Carcinoma, Transitional Cell; Cat Diseases; Cats; Cipr | 1999 |
Quinolone antibiotics: a potential adjunct to intravesical chemotherapy for bladder cancer.
Topics: Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Transitional Cell; Ciprofloxacin; Dose-Resp | 1999 |
Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line.
Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Transitional Cell; CDC2-CDC28 Kinases; Cell Cycle; | 2000 |
Role of mitochondria in ciprofloxacin induced apoptosis in bladder cancer cells.
Topics: Anti-Infective Agents; Apoptosis; bcl-2-Associated X Protein; Calcium; Carcinoma, Transitional Cell; | 2002 |