ciprofloxacin has been researched along with Cancer of Lung in 25 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neutropenic fever is one of the most serious adverse effects of cancer chemotherapy." | 2.71 | Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer. ( Goto, K; Kakinuma, R; Kubota, K; Matsumoto, T; Niho, S; Nishiwaki, Y; Ohe, Y; Ohmatsu, H, 2004) |
| "Ciprofloxacin is an antibiotic that belongs to fluoroquinoles, characterized by broad spectrum of action against pathogens, especially Gram(-) aerobic bacilli." | 2.46 | Does ciprofloxacin have an obverse and a reverse? ( Drewa, T; Gurtowska, N; Kloskowski, T, 2010) |
| "Ciprofloxacin (CIP) is a potent antimicrobial agent with multiple effects on host cells and tissues." | 1.48 | Ciprofloxacin Enhances TRAIL-Induced Apoptosis in Lung Cancer Cells by Upregulating the Expression and Protein Stability of Death Receptors through CHOP Expression. ( Heo, J; Kim, YH; Lee, TH; Lim, EJ; Yoon, YJ, 2018) |
| "The primary in vitro one dose anticancer assay experienced promising cytotoxic activity against different cancer cell lines especially non-small cell lung cancer." | 1.43 | New antiproliferative 7-(4-(N-substituted carbamoylmethyl)piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase. ( Abbas, SH; Abd El-Hafeez, AA; Abdelhafez, EMN; Abuo-Rahma, GEA; Mohammed, HHH, 2016) |
| "Ciprofloxacin was cytostatic only against the A549 cell line." | 1.38 | Ciprofloxacin is a potential topoisomerase II inhibitor for the treatment of NSCLC. ( Adamowicz, J; Dębski, R; Drewa, T; Grzanka, A; Gurtowska, N; Kloskowski, T; Nowak, JM; Olkowska, J; Tworkiewicz, J, 2012) |
| "Ciprofloxacin was given i." | 1.34 | Ciprofloxacin penetration into the pulmonary parenchyma in Japanese patients. ( Endo, N; Haraguchi, S; Hioki, M; Kawamura, J; Koizumi, K; Orii, K; Shimizu, K; Takushima, M; Yamashita, K; Yamashita, Y, 2007) |
| "The "crown gall" hypothesis for Hodgkin's disease would explain the clinical observations of a bacterial infection the behavior as a malignant tumor." | 1.32 | Regression of lung lesions in Hodgkin's disease by antibiotics: case report and hypothesis on the etiology of Hodgkin's disease. ( Blum, S; Sauter, C, 2003) |
| "Pneumonia and acute respiratory distress syndrome are life-threatening complications after pneumonectomy carrying high mortality." | 1.32 | Successful therapy of severe pneumonia-associated ARDS after pneumonectomy with ECMO and steroids. ( Dünser, M; Hasibeder, W; Mayr, AJ; Rieger, M, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.00) | 18.2507 |
| 2000's | 10 (40.00) | 29.6817 |
| 2010's | 12 (48.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamal, A | 1 |
| Shaheer Malik, M | 1 |
| Bajee, S | 1 |
| Azeeza, S | 1 |
| Faazil, S | 1 |
| Ramakrishna, S | 1 |
| Naidu, VG | 1 |
| Vishnuwardhan, MV | 1 |
| Mohammed, HHH | 1 |
| Abd El-Hafeez, AA | 1 |
| Abbas, SH | 1 |
| Abdelhafez, EMN | 1 |
| Abuo-Rahma, GEA | 2 |
| Fawzy, MA | 1 |
| Abu-Baih, RH | 1 |
| Abdel-Rahman, IM | 1 |
| El-Sheikh, AAK | 1 |
| Nazmy, MH | 1 |
| Bykowska, A | 1 |
| Komarnicka, UK | 1 |
| Jeżowska-Bojczuk, M | 1 |
| Kyzioł, A | 1 |
| Lim, EJ | 1 |
| Yoon, YJ | 1 |
| Heo, J | 1 |
| Lee, TH | 1 |
| Kim, YH | 1 |
| Wahl, RU | 1 |
| Megahed, M | 1 |
| Josa Laorden, C | 1 |
| Gómez del Valle, C | 1 |
| Bucar Barjud, M | 1 |
| Amores Arriaga, MB | 1 |
| Torralba Cabeza, MA | 1 |
| Pérez Calvo, JI | 1 |
| Phiboonchaiyanan, PP | 1 |
| Kiratipaiboon, C | 1 |
| Chanvorachote, P | 1 |
| Loriot, Y | 1 |
| Ferte, C | 1 |
| Gomez-Roca, C | 1 |
| Moldovan, C | 1 |
| Bahleda, R | 1 |
| Wislez, M | 1 |
| Cadranel, J | 1 |
| Soria, JC | 1 |
| Kloskowski, T | 2 |
| Gurtowska, N | 2 |
| Drewa, T | 2 |
| Moazeni, E | 1 |
| Gilani, K | 1 |
| Sotoudegan, F | 1 |
| Pardakhty, A | 1 |
| Najafabadi, AR | 1 |
| Ghalandari, R | 1 |
| Fazeli, MR | 1 |
| Jamalifar, H | 1 |
| Schook, RM | 1 |
| Romane, SM | 1 |
| Smit, EF | 1 |
| Egbert, SF | 1 |
| Postmus, PE | 2 |
| Pieter, PE | 1 |
| Hartemink, KJ | 1 |
| Koen, HJ | 1 |
| Paul, MA | 1 |
| Marinus, PA | 1 |
| Olkowska, J | 1 |
| Nowak, JM | 1 |
| Adamowicz, J | 1 |
| Tworkiewicz, J | 1 |
| Dębski, R | 1 |
| Grzanka, A | 1 |
| Williamson, EA | 1 |
| Damiani, L | 1 |
| Leitao, A | 1 |
| Hu, C | 1 |
| Hathaway, H | 1 |
| Oprea, T | 1 |
| Sklar, L | 1 |
| Shaheen, M | 1 |
| Bauman, J | 1 |
| Wang, W | 1 |
| Nickoloff, JA | 1 |
| Lee, SH | 1 |
| Hromas, R | 1 |
| Sauter, C | 1 |
| Blum, S | 1 |
| Niho, S | 1 |
| Ohe, Y | 1 |
| Goto, K | 1 |
| Ohmatsu, H | 1 |
| Matsumoto, T | 1 |
| Kubota, K | 1 |
| Kakinuma, R | 1 |
| Nishiwaki, Y | 1 |
| Dünser, M | 1 |
| Hasibeder, W | 1 |
| Rieger, M | 1 |
| Mayr, AJ | 1 |
| Timmer-Bonte, JN | 1 |
| de Boo, TM | 1 |
| Smit, HJ | 1 |
| Biesma, B | 1 |
| Wilschut, FA | 1 |
| Cheragwandi, SA | 1 |
| Termeer, A | 1 |
| Hensing, CA | 1 |
| Akkermans, J | 1 |
| Adang, EM | 1 |
| Bootsma, GP | 1 |
| Tjan-Heijnen, VC | 2 |
| Marinkovic, M | 1 |
| Witmer, JP | 1 |
| Haraguchi, S | 1 |
| Hioki, M | 1 |
| Yamashita, K | 1 |
| Orii, K | 1 |
| Yamashita, Y | 1 |
| Kawamura, J | 1 |
| Takushima, M | 1 |
| Endo, N | 1 |
| Koizumi, K | 1 |
| Shimizu, K | 1 |
| Bennett, CL | 1 |
| Smith, TJ | 1 |
| George, SL | 1 |
| Hillner, BE | 1 |
| Fleishman, S | 1 |
| Niell, HB | 1 |
| Galley, HF | 1 |
| Nelson, SJ | 1 |
| Dubbels, AM | 1 |
| Webster, NR | 1 |
| Padberg, WM | 1 |
| Jäger, E | 1 |
| Buhr, J | 1 |
| Zimmermann, T | 1 |
| Bunn, PA | 1 |
| Ardizzoni, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Retrospective Study of Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome[NCT01423864] | Phase 2 | 29 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for ciprofloxacin and Cancer of Lung
| Article | Year |
|---|---|
Does ciprofloxacin have an obverse and a reverse?
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cipr | 2010 |
Free-riding and the prisoner's dilemma: problems in funding economic analyses of phase III cancer clinical trials.
Topics: Carcinoma, Non-Small-Cell Lung; Ciprofloxacin; Clinical Trials, Phase III as Topic; Cost-Benefit Ana | 1995 |
2 trials available for ciprofloxacin and Cancer of Lung
| Article | Year |
|---|---|
Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer.
Topics: Administration, Oral; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Infective Agents; Ce | 2004 |
Prevention of chemotherapy-induced febrile neutropenia by prophylactic antibiotics plus or minus granulocyte colony-stimulating factor in small-cell lung cancer: a Dutch Randomized Phase III Study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combin | 2005 |
21 other studies available for ciprofloxacin and Cancer of Lung
| Article | Year |
|---|---|
Synthesis and biological evaluation of conformationally flexible as well as restricted dimers of monastrol and related dihydropyrimidones.
Topics: Anti-Infective Agents; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; | 2011 |
New antiproliferative 7-(4-(N-substituted carbamoylmethyl)piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cel | 2016 |
In Vitro Anticancer Activity of Novel Ciprofloxacin Mannich Base in Lung Adenocarcinoma and High-Grade Serous Ovarian Cancer Cell Lines via Attenuating MAPK Signaling Pathway.
Topics: Adenocarcinoma of Lung; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; | 2023 |
Cu
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apopt | 2018 |
Ciprofloxacin Enhances TRAIL-Induced Apoptosis in Lung Cancer Cells by Upregulating the Expression and Protein Stability of Death Receptors through CHOP Expression.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Ciprofloxacin; Drug Synergism; Enzyme Activation; Gene Knockd | 2018 |
[Erlotinib-induced acneiform eruption].
Topics: Acneiform Eruptions; Adenocarcinoma; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciproflo | 2013 |
Septic shock due to Rhodococcus equi in a patient with chronic myelomonocytic leukemia.
Topics: Actinomycetales Infections; Aged; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Diagnosis, Diffe | 2013 |
Ciprofloxacin mediates cancer stem cell phenotypes in lung cancer cells through caveolin-1-dependent mechanism.
Topics: Anti-Bacterial Agents; Carcinoma, Non-Small-Cell Lung; Caveolin 1; Cell Line, Tumor; Cell Movement; | 2016 |
Pemetrexed-induced pneumonitis: a case report.
Topics: Adrenal Cortex Hormones; Aged; Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Non-Small-Ce | 2009 |
Formulation and in vitro evaluation of ciprofloxacin containing niosomes for pulmonary delivery.
Topics: Aerosols; Anti-Infective Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Ciprofloxacin; Drug De | 2010 |
Benefit of a second opinion for lung cancer: no recurrent disease, but infection.
Topics: Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lun | 2012 |
Ciprofloxacin is a potential topoisomerase II inhibitor for the treatment of NSCLC.
Topics: Actins; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor | 2012 |
Targeting the transposase domain of the DNA repair component Metnase to enhance chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Ciprofloxacin; Cisplatin; DNA Damage; DNA Repair; | 2012 |
Regression of lung lesions in Hodgkin's disease by antibiotics: case report and hypothesis on the etiology of Hodgkin's disease.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Clarithromycin; DNA, Bacterial; F | 2003 |
Successful therapy of severe pneumonia-associated ARDS after pneumonectomy with ECMO and steroids.
Topics: Anti-Inflammatory Agents; Bronchial Fistula; Carcinoma, Bronchogenic; Cilastatin; Ciprofloxacin; Com | 2004 |
[Diagnostic image (299). An oncology patient suffering from conjunctivitis].
Topics: Anti-Infective Agents; Antineoplastic Agents; Antineoplastic Protocols; Carcinoma, Small Cell; Cipro | 2006 |
Ciprofloxacin penetration into the pulmonary parenchyma in Japanese patients.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Carcinoma, Non-Small-Cell Lung; Chromatography, High | 2007 |
Effect of ciprofloxacin on the accumulation of interleukin-6, interleukin-8, and nitrite from a human endothelial cell model of sepsis.
Topics: Anti-Infective Agents; Cell Line; Ciprofloxacin; Drug Evaluation, Preclinical; Endothelium, Vascular | 1997 |
[Ciprofloxacin levels in pleural fluid and serum during systemic administration after pneumonectomy].
Topics: Administration, Oral; Ciprofloxacin; Empyema, Pleural; Female; Humans; Infusions, Intravenous; Lung | 2000 |
Editorial comments on 'Reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study'.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemot | 2001 |
Reply to the article "Editorial comments on 'reduction of chemotherapy-induced febrile leucopenia by prophylactic use of ciprofloxacin and roxithromycin in small-cell lung cancer patients: an EORTC double-blind placebo-controlled phase III study'", by P.
Topics: Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cipro | 2002 |