Page last updated: 2024-10-25

ciprofloxacin and Breast Neoplasms

ciprofloxacin has been researched along with Breast Neoplasms in 23 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Breast Neoplasms: Tumors or cancer of the human BREAST.

Research Excerpts

ExcerptRelevanceReference
"Early-stage breast cancer patients receiving TC chemotherapy were randomised to either ciprofloxacin or G-CSF."9.30Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC). ( Clemons, M; Fergusson, D; Hilton, J; Hutton, B; Ibrahim, MF; Joy, A; Kehoe, A; Mallick, R; Mazzarello, S; Price-Hiller, J; Sienkiewicz, M; Stober, C; Vandermeer, L; Verma, S; Zhu, X, 2019)
" This study was conducted to determine whether oral and intravenous (IV) PTX and Cipro permits increased dose levels of oral busulfan (BU) with a fixed dose of IV cyclophosphamide (CY) in patients with breast cancer receiving autologous or syngeneic hematopoetic cell transplantation."9.11Dose escalation of busulfan with pentoxifylline and ciprofloxacin in patients with breast cancer undergoing autologous transplants. ( Bensinger, WI; Buckner, CD; Holmberg, L; Lilleby, K; Slattery, JT; Storb, R, 2004)
"In a prospective randomized trial, 40 stage IV breast cancer patients undergoing intermediate high-dose chemotherapy (cyclophosphamide, 5-fluorouracil plus epirubicin or methotrexate), received either recombinant human G-CSF (rhG-CSF, group I) or ciprofloxacin and amphotericin B (CAB, group II) for prevention of febrile leucopenia (FL)."9.09Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B. ( de Vries, EG; Hospers, GA; Mulder, NH; Schröder, CP; Sleijfer, DT; van der Graaf, WT; Willemse, PH, 1999)
"This study aimed to investigate the effect of the new ciprofloxacin chalcone [7-(4-(N-substituted carbamoyl methyl) piperazin-1 yl)] on the proliferation, migration, and metastasis of MCF-7 and MDA-MB-231 breast cancer cell lines."8.02Modulation of Apoptosis and Epithelial-Mesenchymal Transition E-cadherin/TGF-β/Snail/TWIST Pathways by a New Ciprofloxacin Chalcone in Breast Cancer Cells. ( Abuo-Rahma, GEA; Alaaeldin, R; Fathy, M; Zhao, QL, 2021)
"We therefore investigated the ability of difloxacin, a quinolone antimicrobial antibiotic, to increase drug cytotoxicity in unselected cultured human neuroblastoma cells."7.71Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin. ( Gilbert, J; Haber, M; Madafiglio, J; Marshall, GM; Norris, MD, 2001)
"Patients with stage T2-T4 primary breast cancer were scheduled to receive 6-8 cycles of TAC."6.73Pegfilgrastim +/- ciprofloxacin for primary prophylaxis with TAC (docetaxel/doxorubicin/cyclophosphamide) chemotherapy for breast cancer. Results from the GEPARTRIO study. ( Costa, SD; du Bois, A; Eidtmann, H; Eiermann, W; Gerber, B; Grasshoff, ST; Hilfrich, J; Huober, J; Jackisch, C; Kaufmann, M; Kümmel, S; Loibl, S; Mehta, KM; Skacel, T; Vescia, S; von Minckwitz, G, 2008)
"Early-stage breast cancer patients receiving TC chemotherapy were randomised to either ciprofloxacin or G-CSF."5.30Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC). ( Clemons, M; Fergusson, D; Hilton, J; Hutton, B; Ibrahim, MF; Joy, A; Kehoe, A; Mallick, R; Mazzarello, S; Price-Hiller, J; Sienkiewicz, M; Stober, C; Vandermeer, L; Verma, S; Zhu, X, 2019)
" This study was conducted to determine whether oral and intravenous (IV) PTX and Cipro permits increased dose levels of oral busulfan (BU) with a fixed dose of IV cyclophosphamide (CY) in patients with breast cancer receiving autologous or syngeneic hematopoetic cell transplantation."5.11Dose escalation of busulfan with pentoxifylline and ciprofloxacin in patients with breast cancer undergoing autologous transplants. ( Bensinger, WI; Buckner, CD; Holmberg, L; Lilleby, K; Slattery, JT; Storb, R, 2004)
"In a prospective randomized trial, 40 stage IV breast cancer patients undergoing intermediate high-dose chemotherapy (cyclophosphamide, 5-fluorouracil plus epirubicin or methotrexate), received either recombinant human G-CSF (rhG-CSF, group I) or ciprofloxacin and amphotericin B (CAB, group II) for prevention of febrile leucopenia (FL)."5.09Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B. ( de Vries, EG; Hospers, GA; Mulder, NH; Schröder, CP; Sleijfer, DT; van der Graaf, WT; Willemse, PH, 1999)
"We studied the effectiveness of prophylactic oral ciprofloxacin and rifampin on fever prevention in patients undergoing autologous bone marrow transplantation (ABMT) for breast cancer."5.07Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support. ( Gilbert, C; Hussein, A; Meisenberg, B; Perfect, J; Peters, WP; Ross, M; Vredenburgh, J, 1994)
"This study aimed to investigate the effect of the new ciprofloxacin chalcone [7-(4-(N-substituted carbamoyl methyl) piperazin-1 yl)] on the proliferation, migration, and metastasis of MCF-7 and MDA-MB-231 breast cancer cell lines."4.02Modulation of Apoptosis and Epithelial-Mesenchymal Transition E-cadherin/TGF-β/Snail/TWIST Pathways by a New Ciprofloxacin Chalcone in Breast Cancer Cells. ( Abuo-Rahma, GEA; Alaaeldin, R; Fathy, M; Zhao, QL, 2021)
"Of the 60 consecutive patients who received neoadjuvant chemotherapy as a phase II trial of docetaxel (60 mg/m(2)) and doxorubicin (50 mg/m(2)) for primary breast cancer, 30 low-risk febrile patients received oral ciprofloxacin."3.74The outpatient management of low-risk febrile patients with neutropenia: risk assessment over the telephone. ( Ando, M; Katsumata, N; Mizuno, T; Mukai, H; Shimizu, C; Watanabe, T, 2007)
"We therefore investigated the ability of difloxacin, a quinolone antimicrobial antibiotic, to increase drug cytotoxicity in unselected cultured human neuroblastoma cells."3.71Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin. ( Gilbert, J; Haber, M; Madafiglio, J; Marshall, GM; Norris, MD, 2001)
"Patients with stage T2-T4 primary breast cancer were scheduled to receive 6-8 cycles of TAC."2.73Pegfilgrastim +/- ciprofloxacin for primary prophylaxis with TAC (docetaxel/doxorubicin/cyclophosphamide) chemotherapy for breast cancer. Results from the GEPARTRIO study. ( Costa, SD; du Bois, A; Eidtmann, H; Eiermann, W; Gerber, B; Grasshoff, ST; Hilfrich, J; Huober, J; Jackisch, C; Kaufmann, M; Kümmel, S; Loibl, S; Mehta, KM; Skacel, T; Vescia, S; von Minckwitz, G, 2008)
"Treatment of ADG-2e against metastatic breast cancer cells (MDA-MB-231) suppressed tumor cell migration by multi-directional lamellipodium formation, indicating their anti-metastatic potential."1.56Antibacterial AZT derivative regulates metastasis of breast cancer cells. ( Bang, JK; Chirumarry, S; Gunasekaran, P; Han, J; Kim, EY; Lee, YH; Ryu, EK; Shin, SY; Soung, NK, 2020)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (17.39)18.2507
2000's9 (39.13)29.6817
2010's7 (30.43)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Al-Trawneh, SA2
Zahra, JA2
Kamal, MR1
El-Abadelah, MM2
Zani, F2
Incerti, M2
Cavazzoni, A2
Alfieri, RR1
Petronini, PG1
Vicini, P2
Al-Taweel, SA1
Kamal, A1
Shaheer Malik, M1
Bajee, S1
Azeeza, S1
Faazil, S1
Ramakrishna, S1
Naidu, VG1
Vishnuwardhan, MV1
Chirumarry, S1
Soung, NK1
Han, J1
Kim, EY1
Ryu, EK1
Lee, YH1
Shin, SY1
Gunasekaran, P1
Bang, JK1
Joya, CA1
Deegan, C1
Gleeson, TD1
Alaaeldin, R1
Abuo-Rahma, GEA1
Zhao, QL1
Fathy, M1
Clemons, M1
Mazzarello, S1
Hilton, J1
Joy, A1
Price-Hiller, J1
Zhu, X1
Verma, S1
Kehoe, A1
Ibrahim, MF1
Sienkiewicz, M1
Stober, C1
Vandermeer, L1
Hutton, B1
Mallick, R1
Fergusson, D1
Elktaibi, A1
Elochi, MR1
Sinaa, M1
Allaoui, M1
Alami, Y1
Amrani, M1
Sulpher, J1
Giguere, P1
Hopkins, S1
Dent, S1
Kitada, N1
Nishino, M1
Yasuda, J1
Morita, S1
Fujii, C1
Minegaki, T1
Kondoh, M1
Anami, S1
Takara, K1
Watari, M1
Shi, ZY1
Li, YQ1
Kang, YH1
Hu, GQ1
Huang-fu, CS1
Deng, JB1
Liu, B1
Gowda, RV1
Stout, R1
Smith, RE1
Bryant, J1
DeCillis, A1
Anderson, S1
Bensinger, WI1
Buckner, CD1
Lilleby, K1
Holmberg, L1
Storb, R1
Slattery, JT1
Mizuno, T1
Katsumata, N1
Mukai, H1
Shimizu, C1
Ando, M1
Watanabe, T1
von Minckwitz, G1
Kümmel, S1
du Bois, A1
Eiermann, W1
Eidtmann, H1
Gerber, B1
Hilfrich, J1
Huober, J1
Costa, SD1
Jackisch, C1
Grasshoff, ST1
Vescia, S1
Skacel, T1
Loibl, S1
Mehta, KM1
Kaufmann, M1
Elwood, ET1
Sommerville, DN1
Murray, JD1
Hsu, PK1
Hsu, WH1
Eidelman, G1
Shapira, Y1
Lishner, M1
Shalit, I1
Kletter, Y1
Fabian, I1
Gilbert, C1
Meisenberg, B1
Vredenburgh, J1
Ross, M1
Hussein, A1
Perfect, J1
Peters, WP1
Bloch, KC1
Nadarajah, R1
Jacobs, R1
Schröder, CP1
de Vries, EG1
Mulder, NH1
Willemse, PH1
Sleijfer, DT1
Hospers, GA1
van der Graaf, WT1
Norris, MD1
Madafiglio, J1
Gilbert, J1
Marshall, GM1
Haber, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility of Using an Integrated Consent Model to Compare Two Standard of Care Regimens for Primary Prophylaxis of Taxotere/Cyclophosphamide-Induces Febrile Neutropenia[NCT02173262]Phase 4142 participants (Actual)Interventional2014-08-31Completed
Intermittent Every Other Days of 5 Shot-filgrastim Compared With Single Pegfilgrastim in Breast Cancer Patients Receiving Adjuvant Docetaxel, Doxorubicin, and Cyclophosphamide Chemotherapy (Intermittent G-CSF 105)[NCT02685111]Phase 222 participants (Actual)Interventional2016-02-29Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ciprofloxacin and Breast Neoplasms

ArticleYear
Chryseobacterium meningosepticum: an emerging pathogen among immunocompromised adults. Report of 6 cases and literature review.
    Medicine, 1997, Volume: 76, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotics, Antitubercular; Breast Neoplasms; Ciprofloxacin; Dr

1997

Trials

7 trials available for ciprofloxacin and Breast Neoplasms

ArticleYear
Feasibility of using a pragmatic trials model to compare two primary febrile neutropenia prophylaxis regimens (ciprofloxacin versus G-CSF) in patients receiving docetaxel-cyclophosphamide chemotherapy for breast cancer (REaCT-TC).
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019, Volume: 27, Issue:4

    Topics: Adult; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cip

2019
[Equalization of breast cancer chemotherapy at general hospital( II )-evaluation of safety in FEC and TC regimens].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Breast Neoplasms; Ciprofloxa

2009
Dose escalation of busulfan with pentoxifylline and ciprofloxacin in patients with breast cancer undergoing autologous transplants.
    Oncology, 2004, Volume: 67, Issue:5-6

    Topics: Adult; Anti-Infective Agents; Bone Marrow Transplantation; Breast Neoplasms; Busulfan; Ciprofloxacin

2004
Pegfilgrastim +/- ciprofloxacin for primary prophylaxis with TAC (docetaxel/doxorubicin/cyclophosphamide) chemotherapy for breast cancer. Results from the GEPARTRIO study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2008, Volume: 19, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxacin; Cyclop

2008
Effect of ciprofloxacin on hematologic parameters in breast cancer patients receiving chemotherapy.
    European journal of haematology, 1995, Volume: 55, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Count; Ciprofloxacin; C

1995
Sequential prophylactic oral and empiric once-daily parenteral antibiotics for neutropenia and fever after high-dose chemotherapy and autologous bone marrow support.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:5

    Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; B

1994
Prevention of febrile leucopenia after chemotherapy in high-risk breast cancer patients: no significant difference between granulocyte-colony stimulating growth factor or ciprofloxacin plus amphotericin B.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 43, Issue:5

    Topics: Adult; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxac

1999

Other Studies

15 other studies available for ciprofloxacin and Breast Neoplasms

ArticleYear
Synthesis and biological evaluation of tetracyclic fluoroquinolones as antibacterial and anticancer agents.
    Bioorganic & medicinal chemistry, 2010, Aug-15, Volume: 18, Issue:16

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell

2010
Synthesis and biological evaluation of tetracyclic thienopyridones as antibacterial and antitumor agents.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell

2011
Synthesis and biological evaluation of conformationally flexible as well as restricted dimers of monastrol and related dihydropyrimidones.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:8

    Topics: Anti-Infective Agents; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms;

2011
Antibacterial AZT derivative regulates metastasis of breast cancer cells.
    European journal of medicinal chemistry, 2020, May-01, Volume: 193

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Cell Proliferation; C

2020
    BMJ case reports, 2021, Feb-04, Volume: 14, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Breast Neoplasms; Ciprofloxacin; Debridement; Doxycycline; Female; Hum

2021
Modulation of Apoptosis and Epithelial-Mesenchymal Transition E-cadherin/TGF-β/Snail/TWIST Pathways by a New Ciprofloxacin Chalcone in Breast Cancer Cells.
    Anticancer research, 2021, Volume: 41, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cadherins; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival;

2021
[Pseudotumoral malakoplakia of the breast].
    The Pan African medical journal, 2015, Volume: 21

    Topics: Breast Neoplasms; Ciprofloxacin; Female; Humans; Malacoplakia; Middle Aged; Tuberculosis

2015
Impact of an electronic tool in prescribing primary prophylaxis with ciprofloxacin or granulocyte colony-stimulating factor for breast cancer patients receiving TC chemotherapy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:7

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Ciprofloxacin; Female

2016
Piperonal ciprofloxacin hydrazone induces growth arrest and apoptosis of human hepatocarcinoma SMMC-7721 cells.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Cell

2012
Pasteurella multocida infection in a post-chemotherapy neutropenic host following cat exposure.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2002, Volume: 14, Issue:6

    Topics: Aged; Animals; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplas

2002
Acute myeloid leukemia and myelodysplastic syndrome after doxorubicin-cyclophosphamide adjuvant therapy for operable breast cancer: the National Surgical Adjuvant Breast and Bowel Project Experience.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Apr-01, Volume: 21, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cipr

2003
The outpatient management of low-risk febrile patients with neutropenia: risk assessment over the telephone.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2007, Volume: 15, Issue:3

    Topics: Adult; Aged; Ambulatory Care; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols;

2007
Periorbital necrotizing fasciitis.
    Plastic and reconstructive surgery, 2007, Volume: 120, Issue:7

    Topics: Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Breast Neoplasms;

2007
Chest wall mass caused by salmonella enteritidis - a pitfall of PET imaging interpretation.
    The Thoracic and cardiovascular surgeon, 2008, Volume: 56, Issue:4

    Topics: Aged; Anti-Infective Agents; Breast Neoplasms; Ceftriaxone; Ciprofloxacin; Female; Fluorodeoxyglucos

2008
Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin.
    Medical and pediatric oncology, 2001, Volume: 36, Issue:1

    Topics: Adenocarcinoma; Anti-Infective Agents; Antimony Potassium Tartrate; ATP-Binding Cassette Transporter

2001