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ciprofloxacin and Bladder Cancer

ciprofloxacin has been researched along with Bladder Cancer in 15 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"Oral ciprofloxacin might achieve higher concentration in urine than in serum; theoretically, this drug might act as an anticancer drug against bladder cancer cells."8.86Ciprofloxacin criteria in antimicrobial prophylaxis and bladder cancer recurrence. ( Drewa, T; Gurtowska, N; Kloskowski, T, 2010)
"The disruption of calcium homeostasis, mitochondrial swelling and redistribution of Bax to the mitochondrial membrane are key events in the initiation of apoptotic processes in ciprofloxacin treated bladder cancer cells."7.71Role of mitochondria in ciprofloxacin induced apoptosis in bladder cancer cells. ( Alhasan, S; Aranha, O; Kuo, TH; Sarkar, FH; Wood, DP; Zhu, L, 2002)
"The results of this study show that both ciprofloxacin, chosen for its use as possible radiosensitizing agent in bladder cancer patients, and hydrocortisone, chosen as an example of lypofilic endogenous compound, can be absorbed through the intestinal mucosa of a continent ileal reservoir, but to a different extent and with high interindividual variability."5.12Interindividual variability in the absorption of ciprofloxacin and hydrocortisone from continent ileal reservoir for urine. ( Corbu, C; Garbero, C; Gosmar, M; Manfredi, V; Martelli, A; Mattioli, F; Tognoni, P, 2006)
"Oral ciprofloxacin might achieve higher concentration in urine than in serum; theoretically, this drug might act as an anticancer drug against bladder cancer cells."4.86Ciprofloxacin criteria in antimicrobial prophylaxis and bladder cancer recurrence. ( Drewa, T; Gurtowska, N; Kloskowski, T, 2010)
"The disruption of calcium homeostasis, mitochondrial swelling and redistribution of Bax to the mitochondrial membrane are key events in the initiation of apoptotic processes in ciprofloxacin treated bladder cancer cells."3.71Role of mitochondria in ciprofloxacin induced apoptosis in bladder cancer cells. ( Alhasan, S; Aranha, O; Kuo, TH; Sarkar, FH; Wood, DP; Zhu, L, 2002)
"Four patients had had cervical cancer, five had uterine cancer, one had prostatic cancer, one had vesical cancer and one had vaginal cancer."1.37A novel treatment for haemorrhagic radiation proctitis using colonic irrigation and oral antibiotic administration. ( Atittharnsakul, P; Patiwongpaisarn, A; Rojanasakul, A; Sahakitrungruang, C; Thum-Umnuaysuk, S, 2011)
"The recurrence rate for superficial bladder tumors treated with complete resection averages 88%."1.32Antitumor activity of common antibiotics against superficial bladder cancer. ( Kamat, AM; Lamm, DL, 2004)
"Ciprofloxacin (200 mg) was administered iv, and intestinal samples were collected over a 120-min period."1.31Transepithelial intestinal excretion of ciprofloxacin in humans. ( Ben-Haim, M; Ramon, J; Rubinstein, E; Shabtai, M, 2001)
"Ciprofloxacin and ofloxacin inhibit proliferation and DNA synthesis of these 3 human TCC lines in vitro."1.29Inhibition of human transitional cell carcinoma in vitro proliferation by fluoroquinolone antibiotics. ( Dixon, PS; Peretsman, SJ; Seay, TM, 1996)
"Ciprofloxacin was tested for its effect on proliferation of a bladder carcinoma cell line, Jurkat T-cell leukaemia cell line and a normal human foreskin derived from a fibroblast cell line."1.28The inhibitory effect of ciprofloxacin on proliferation of a murine bladder carcinoma cell line. ( Shalit, I; Zehavi-Willner, T, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's7 (46.67)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Xu, H1
Cao, X1
Zhang, W1
Li, Q1
Gurtowska, N1
Kloskowski, T1
Drewa, T1
Sahakitrungruang, C1
Thum-Umnuaysuk, S1
Patiwongpaisarn, A1
Atittharnsakul, P1
Rojanasakul, A1
Durek, C1
Jurczok, A1
Werner, H1
Jocham, D1
Bohle, A1
Kamat, AM2
Lamm, DL2
Mattioli, F1
Tognoni, P1
Manfredi, V1
Gosmar, M1
Corbu, C1
Garbero, C1
Martelli, A1
Burgués, JP1
Gómez, L1
Pontones, JL1
Vera, CD1
Jiménez-Cruz, JF1
Ozonas, M1
Seay, TM1
Peretsman, SJ1
Dixon, PS1
Ebisuno, S1
Inagaki, T1
Kohjimoto, Y1
Ohkawa, T1
Beatty, JA1
Martin, P1
Kendall, K1
Malik, R1
DeHaven, JI1
Aranha, O2
Wood, DP2
Sarkar, FH2
Ramon, J1
Ben-Haim, M1
Shabtai, M1
Rubinstein, E1
Zhu, L1
Alhasan, S1
Kuo, TH1
Zehavi-Willner, T1
Shalit, I1

Reviews

1 review available for ciprofloxacin and Bladder Cancer

ArticleYear
Ciprofloxacin criteria in antimicrobial prophylaxis and bladder cancer recurrence.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:10

    Topics: Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Transitional Cell; Cell Line, Tumor; Ciprof

2010

Trials

1 trial available for ciprofloxacin and Bladder Cancer

ArticleYear
Interindividual variability in the absorption of ciprofloxacin and hydrocortisone from continent ileal reservoir for urine.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:2

    Topics: Administration, Intravesical; Aged; Analysis of Variance; Carcinoma, Transitional Cell; Ciprofloxaci

2006

Other Studies

13 other studies available for ciprofloxacin and Bladder Cancer

ArticleYear
Co-existence of two ciprofloxacin-resistant Salmonella enterica serovar Kentucky strains in the urine of a bladder cancer patient.
    Journal of global antimicrobial resistance, 2022, Volume: 30

    Topics: Ciprofloxacin; Humans; Kentucky; Salmonella enterica; Serogroup; Urinary Bladder Neoplasms

2022
A novel treatment for haemorrhagic radiation proctitis using colonic irrigation and oral antibiotic administration.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2011, Volume: 13, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Ciprofloxacin; Combined Modality Therapy; Female; Ga

2011
Optimal treatment of systemic bacillus Calmette-Guérin infection: investigations in an animal model.
    The Journal of urology, 2002, Volume: 168, Issue:2

    Topics: Animals; Cell Survival; Ciprofloxacin; Disease Models, Animal; Dose-Response Relationship, Drug; Dru

2002
Antitumor activity of common antibiotics against superficial bladder cancer.
    Urology, 2004, Volume: 63, Issue:3

    Topics: Antibiotics, Antineoplastic; Carcinoma, Transitional Cell; Cefazolin; Cell Line, Tumor; Ciprofloxaci

2004
A chemosensitivity test for superficial bladder cancer based on three-dimensional culture of tumour spheroids.
    European urology, 2007, Volume: 51, Issue:4

    Topics: Antineoplastic Agents; Ciprofloxacin; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays,

2007
Inhibition of human transitional cell carcinoma in vitro proliferation by fluoroquinolone antibiotics.
    The Journal of urology, 1996, Volume: 155, Issue:2

    Topics: Anti-Infective Agents; Carcinoma, Transitional Cell; Cell Division; Ciprofloxacin; Dose-Response Rel

1996
The cytotoxic effect of fleroxacin and ciprofloxacin on transitional cell carcinoma in vitro.
    Cancer, 1997, Dec-15, Volume: 80, Issue:12

    Topics: Animals; Anti-Infective Agents; Carcinoma, Transitional Cell; Cell Count; Cell Division; Cell Surviv

1997
Haematuria in a geriatric cat.
    Australian veterinary journal, 1999, Volume: 77, Issue:3

    Topics: Animals; Anti-Infective Agents; Azure Stains; Carcinoma, Transitional Cell; Cat Diseases; Cats; Cipr

1999
Quinolone antibiotics: a potential adjunct to intravesical chemotherapy for bladder cancer.
    Urology, 1999, Volume: 54, Issue:1

    Topics: Anti-Infective Agents; Antineoplastic Agents; Carcinoma, Transitional Cell; Ciprofloxacin; Dose-Resp

1999
Ciprofloxacin mediated cell growth inhibition, S/G2-M cell cycle arrest, and apoptosis in a human transitional cell carcinoma of the bladder cell line.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Apoptosis; bcl-2-Associated X Protein; Carcinoma, Transitional Cell; CDC2-CDC28 Kinases; Cell Cycle;

2000
Transepithelial intestinal excretion of ciprofloxacin in humans.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Mar-01, Volume: 32, Issue:5

    Topics: Aged; Anti-Infective Agents; Cecum; Ciprofloxacin; Colonic Neoplasms; Female; Humans; Ileum; Intesti

2001
Role of mitochondria in ciprofloxacin induced apoptosis in bladder cancer cells.
    The Journal of urology, 2002, Volume: 167, Issue:3

    Topics: Anti-Infective Agents; Apoptosis; bcl-2-Associated X Protein; Calcium; Carcinoma, Transitional Cell;

2002
The inhibitory effect of ciprofloxacin on proliferation of a murine bladder carcinoma cell line.
    The Journal of antimicrobial chemotherapy, 1992, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Division; Ciprofloxacin; Fibroblasts; Humans; Kinetics; Lymphom

1992