Page last updated: 2024-10-25

ciprofloxacin and Benign Neoplasms

ciprofloxacin has been researched along with Benign Neoplasms in 98 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to test the efficacy of oral ciprofloxacin in the treatment of lower risk febrile neutropenia (LRFN) in children treated for malignant diseases."9.09Oral ciprofloxacin in the management of children with cancer with lower risk febrile neutropenia. ( Armada, A; Cáceres, E; Casimir, L; Debbag, R; Fernández, C; Firpo, V; Latella, A; Paganini, H; Rodriguez-Brieshcke, T; Zubizarreta, P, 2001)
"Outpatient therapy with either oral ciprofloxacin or intravenous ceftriaxone for fever and neutropenia is effective and safe in pediatric patients with solid tumors and stage I/II non-Hodgkin lymphoma (low-risk patients)."9.09Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial. ( Campos, MC; Dantas, LS; Ginani, VC; Petrilli, AS; Seber, A; Tanaka, C, 2000)
" The use of monotherapy with intravenous ciprofloxacin (200 to 300 mg every 12 h) was evaluated against combined therapy with piperacillin plus amikacin in febrile granulocytopenic patients with solid tumor or lymphoma."9.07Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with lymphomas and solid tumors. The European Organization for Research on Treatment of Cancer ( Calandra, T; Gaya, H; Glauser, M; Klastersky, J; Meunier, F; Viscoli, C; Zinner, SH, 1991)
"To compare the effectiveness and toxicity of ciprofloxacin vs an aminoglycoside, both in combination with a beta-lactam, for the treatment of febrile neutropenia in the inpatient setting."8.82Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials. ( Bliziotis, IA; Christodoulou, C; Chrysanthopoulou, S; Falagas, ME; Kasiakou, SK; Michalopoulos, A; Samonis, G, 2005)
"The objective of this investigation was to assess retrospectively the safety and the efficacy of oral ciprofloxacin plus cefuroxime axetil compared to the combination of oral ciprofloxacin plus amoxicillin/clavulanate, as initial outpatient treatment, in low-risk cancer patients with fever and neutropenia."7.74Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate. ( Karabelis, A; Kordossis, T; Kosmas, C; Sipsas, NV; Skopelitis, E; Tsavaris, N; Vadiaka, M; Ziakas, PD, 2007)
"The current study demonstrates that very carefully selected, low risk patients with febrile neutropenia may be treated successfully without hospitalization using oral ciprofloxacin."7.70Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer. ( Aquino, VM; Buchanan, GR; Herrera, L; Sandler, ES, 2000)
"Hospitalized patients with sepsis caused by ciprofloxacin-susceptible organisms were treated with intravenous ciprofloxacin 300 mg every 12 hours."7.67Treatment of sepsis in patients with neoplastic diseases with intravenous ciprofloxacin. ( Brown, AE; Smith, G, 1989)
"Inclusion criteria were cancer, febrile neutropenia, low risk of complications as predicted by a Multinational Association for Supportive Care in Cancer (MASCC) score > 20, ability to swallow, and ≤ one single intravenous dose of empiric antibiotic therapy before study drug treatment initiation."6.78Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectiou ( Akan, H; Akova, M; Aoun, M; Calandra, T; de Bock, R; Drgona, L; Kern, WV; Marchetti, O; Paesmans, M; Viscoli, C, 2013)
"Pediatric cancer patients presenting with febrile neutropenia after non-myeloablative chemotherapy and who met institutional criteria for early hospital discharge following a minimum of 48-hr inpatient empiric intravenous ceftazidime were eligible for the study."6.71Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients. ( Burns, JL; Coughlin, J; Friedman, DL; Hawkins, D; Park, JR; Pendergrass, T, 2003)
" The bioavailability of ciprofloxacin appeared comparable to that found in previously published studies of normal volunteers and patients not receiving chemotherapy."6.67Prophylaxis of bacterial infections with ciprofloxacin in patients undergoing bone marrow transplantation. ( Antman, KH; Finberg, R; Kalish, L; Kehoe, K; Lew, MA; Mayer, R; Nadler, L; Ritz, J; Takvorian, T, 1991)
"The incidence and of bacterial infections, and resulting mortality, among cancer patients is growing dramatically, worldwide."5.72Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer. ( Devnarain, N; Gafar, MA; Govender, T; Ibrahim, UH; Khan, R; Mocktar, C; Mohammed, M; Oh, JK; Omolo, CA; Pant, A; Salih, M; Shunmugam, L, 2022)
"Evaluation of benzylpenicillin (penicillin G) effect for infection prophylaxis at the oncological patients with severe postcytostatic neutropenia was performed."5.10[Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia]. ( Chimishkian, KL; Dmitrieva, NV; Larionova, VB; Minenko, SV; Ptushkin, VV; Sokolova, EN; Zhukov, NV, 2002)
"In hospitalized low-risk patients who have fever and neutropenia during cancer chemotherapy, empirical therapy with oral ciprofloxacin and amoxicillin-clavulanate is safe and effective."5.09A double-blind comparison of empirical oral and intravenous antibiotic therapy for low-risk febrile patients with neutropenia during cancer chemotherapy. ( Chanock, S; Freifeld, A; Gill, V; Hicks, JE; Hiemenz, J; Hiemenz, S; Lewis, L; Marchigiani, D; Pizzo, PA; Steinberg, SM; Walsh, T, 1999)
"The objective of this study was to test the efficacy of oral ciprofloxacin in the treatment of lower risk febrile neutropenia (LRFN) in children treated for malignant diseases."5.09Oral ciprofloxacin in the management of children with cancer with lower risk febrile neutropenia. ( Armada, A; Cáceres, E; Casimir, L; Debbag, R; Fernández, C; Firpo, V; Latella, A; Paganini, H; Rodriguez-Brieshcke, T; Zubizarreta, P, 2001)
"To determine whether the addition of rifampin to a quinolone-based antibacterial prophylactic regimen in patients undergoing high-dose chemotherapy (HDC) with peripheral-blood stem-cell transplantation (PBSCT) decreases the incidence of neutropenia and fever, Gram-positive bacteremia, and infection-related morbidity."5.09Rifampin does not improve the efficacy of quinolone antibacterial prophylaxis in neutropenic cancer patients: results of a randomized clinical trial. ( Arcediano, A; Cortés-Funes, H; Gomez-Martin, C; Hidalgo, M; Hornedo, J; Lumbreras, C; Perea, S; Rodriguez, M; Salazar, R; Solá, C; Valentí, V, 2000)
"Outpatient therapy with either oral ciprofloxacin or intravenous ceftriaxone for fever and neutropenia is effective and safe in pediatric patients with solid tumors and stage I/II non-Hodgkin lymphoma (low-risk patients)."5.09Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial. ( Campos, MC; Dantas, LS; Ginani, VC; Petrilli, AS; Seber, A; Tanaka, C, 2000)
"In low-risk patients with cancer who have fever and granulocytopenia, oral therapy with ciprofloxacin plus amoxicillin-clavulanate is as effective as intravenous therapy."5.09Oral versus intravenous empirical antimicrobial therapy for fever in patients with granulocytopenia who are receiving cancer chemotherapy. International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Can ( Cometta, A; De Bock, R; Gaya, H; Kern, WV; Langenaeken, J; Paesmans, M, 1999)
" The use of monotherapy with intravenous ciprofloxacin (200 to 300 mg every 12 h) was evaluated against combined therapy with piperacillin plus amikacin in febrile granulocytopenic patients with solid tumor or lymphoma."5.07Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with lymphomas and solid tumors. The European Organization for Research on Treatment of Cancer ( Calandra, T; Gaya, H; Glauser, M; Klastersky, J; Meunier, F; Viscoli, C; Zinner, SH, 1991)
"To compare the effectiveness and toxicity of ciprofloxacin vs an aminoglycoside, both in combination with a beta-lactam, for the treatment of febrile neutropenia in the inpatient setting."4.82Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials. ( Bliziotis, IA; Christodoulou, C; Chrysanthopoulou, S; Falagas, ME; Kasiakou, SK; Michalopoulos, A; Samonis, G, 2005)
"The objective of this investigation was to assess retrospectively the safety and the efficacy of oral ciprofloxacin plus cefuroxime axetil compared to the combination of oral ciprofloxacin plus amoxicillin/clavulanate, as initial outpatient treatment, in low-risk cancer patients with fever and neutropenia."3.74Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate. ( Karabelis, A; Kordossis, T; Kosmas, C; Sipsas, NV; Skopelitis, E; Tsavaris, N; Vadiaka, M; Ziakas, PD, 2007)
"The current study demonstrates that very carefully selected, low risk patients with febrile neutropenia may be treated successfully without hospitalization using oral ciprofloxacin."3.70Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer. ( Aquino, VM; Buchanan, GR; Herrera, L; Sandler, ES, 2000)
"The susceptibility of clinical isolates of methicillin-susceptible and -resistant staphylococci from cancer patients with central venous catheter bacteremia to quinupristin/dalfopristin, a semisynthetic streptogramin, was determined in vitro."3.69In vitro study of the potential role of quinupristin/dalfopristin in the treatment of catheter-related staphylococcal infections. ( Garcia, R; Raad, I, 1996)
"Hospitalized patients with sepsis caused by ciprofloxacin-susceptible organisms were treated with intravenous ciprofloxacin 300 mg every 12 hours."3.67Treatment of sepsis in patients with neoplastic diseases with intravenous ciprofloxacin. ( Brown, AE; Smith, G, 1989)
"Inclusion criteria were cancer, febrile neutropenia, low risk of complications as predicted by a Multinational Association for Supportive Care in Cancer (MASCC) score > 20, ability to swallow, and ≤ one single intravenous dose of empiric antibiotic therapy before study drug treatment initiation."2.78Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectiou ( Akan, H; Akova, M; Aoun, M; Calandra, T; de Bock, R; Drgona, L; Kern, WV; Marchetti, O; Paesmans, M; Viscoli, C, 2013)
"We treated low-risk febrile neutropenic cancer patients utilizing two standard outpatient antibiotic pathways: oral ampicillin/clavulanate (500 mg) and ciprofloxacin (500 mg) or intravenous ceftazidime (2 g) and clindamycin (600 mg) every 8 h."2.71Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients. ( Badrina, N; Benjamin, R; DeJesus, Y; Escalante, CP; Fernandez, S; Ho, V; Lam, T; Lee, EL; Manzullo, E; Rivera, E; Rolston, K; Valdres, R; Weiser, MA, 2004)
"Pediatric cancer patients presenting with febrile neutropenia after non-myeloablative chemotherapy and who met institutional criteria for early hospital discharge following a minimum of 48-hr inpatient empiric intravenous ceftazidime were eligible for the study."2.71Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients. ( Burns, JL; Coughlin, J; Friedman, DL; Hawkins, D; Park, JR; Pendergrass, T, 2003)
" The bioavailability of ciprofloxacin appeared comparable to that found in previously published studies of normal volunteers and patients not receiving chemotherapy."2.67Prophylaxis of bacterial infections with ciprofloxacin in patients undergoing bone marrow transplantation. ( Antman, KH; Finberg, R; Kalish, L; Kehoe, K; Lew, MA; Mayer, R; Nadler, L; Ritz, J; Takvorian, T, 1991)
"The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant cancers make an urgent need to develop more effective anti-cancer candidates."2.61Quinolone hybrids and their anti-cancer activities: An overview. ( Gao, F; Wang, T; Xiao, J; Zhang, X, 2019)
"Ciprofloxacin (CP) is a fluoroquinolone that is highly active against diverse microorganisms."2.49Medicinal potential of ciprofloxacin and its derivatives. ( Biot, C; Castro, W; Navarro, M, 2013)
"Thus, up to date management of cancer patients, in addition to other supportive care modalities, should also incorporate diagnostic methods and therapy of infections."2.47[Treatment and prevention of infections in cancer patients with neutropenia]. ( Sinkó, J, 2011)
"Patients who are treated for acute leukemia should be offered prophylaxis with ciprofloxacin or levofloxacin."2.43Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions. ( Bucaneve, G; Cullen, M; Fraser, A; Gafter-Gvili, A; Kern, WV; Leibovici, L; Paul, M, 2006)
"In general, patients with Crohn's disease are not usually offered IPAA, because recurrence of disease, fistulas, abscesses, and strictures may lead to a higher incidence of pouch failure."2.41Complications after ileal pouch-anal anastomosis. ( Lichtenstein, GR; Stein, RB, 2000)
"Allergic interstitial nephritis is believed to be the underlying pathological-process."2.38Ciprofloxacin-induced nephrotoxicity in patients with cancer. ( Bodey, GP; Lo, WK; Rolston, KV; Rubenstein, EB, 1993)
"Ciprofloxacin is a fluoroquinolone, widely used because of its broad spectrum antimicrobial activity and favorable pharmacokinetic properties."1.91Administration of ciprofloxacin through a nasogastric tube in pediatric oncology and stem cell transplantation patients. ( Bauters, T; Buyle, F; Dhooge, C; Schelstraete, P, 2023)
"The incidence and of bacterial infections, and resulting mortality, among cancer patients is growing dramatically, worldwide."1.72Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer. ( Devnarain, N; Gafar, MA; Govender, T; Ibrahim, UH; Khan, R; Mocktar, C; Mohammed, M; Oh, JK; Omolo, CA; Pant, A; Salih, M; Shunmugam, L, 2022)
"Antimicrobial resistance and cancer are two important problems affecting human health."1.62Antibacterial and antitumoral properties of 1,2,3-triazolo fused triterpenes and their mechanism of inhibiting the proliferation of HL-60 cells. ( Daelemans, D; De Jonghe, S; Dehaen, W; Hu, H; Krasniqi, B; Li, Y; Luyten, W; Persoons, L; Wang, R, 2021)
"Interestingly, cancer stem cell counts increased significantly in the presence of EB."1.62The effects of biofilms on tumor progression in a 3D cancer-biofilm microfluidic model. ( Chua, SL; Deng, Y; Khoo, BL; Liu, SY, 2021)
"Febrile neutropenia: is ambulatory care possible ? Outpatient treatment of neutropenic fever post chemotherapy is possible for patients at low risk of complications."1.46[Febrile neutropenia: is ambulatory care possible]? ( Lafaurie, M, 2017)
"The primary in vitro one dose anticancer assay experienced promising cytotoxic activity against different cancer cell lines especially non-small cell lung cancer."1.43New antiproliferative 7-(4-(N-substituted carbamoylmethyl)piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase. ( Abbas, SH; Abd El-Hafeez, AA; Abdelhafez, EMN; Abuo-Rahma, GEA; Mohammed, HHH, 2016)
"Ciprofloxacin resistance was more frequent in children who shared an environment with adults who were receiving ciprofloxacin prophylaxis."1.33Differences in the proportions of fluoroquinolone-resistant Gram-negative bacteria isolated from bacteraemic children with cancer in two Italian centres. ( Castagnola, E; Caviglia, I; Giona, F; Girmenia, C; Haupt, R; Micozzi, A; Parodi, S; Testi, AM, 2005)
"Trovafloxacin was also the most active agent tested against Gram-positive organisms, including ciprofloxacin-susceptible strains and most ciprofloxacin- and methicillin-resistant staphylococci and enterococci."1.30In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer. ( Dvorak, T; Ho, DH; LeBlanc, B; Rolston, KV; Streeter, H, 1997)
"No bacteremia was noted."1.29Prophylactic antibiotics eliminate bacteremia and allow safe outpatient management following high-dose chemotherapy and autologous stem cell rescue. ( Brehm, T; Gollard, R; McMillan, R; Meisenberg, B; Miller, W, 1996)
"Sparfloxacin was extremely active against Acinetobacter species, Aeromonas hydrophila, Citrobacter diversus, Enterobacter species, Escherichia coli, Klebsiella species, Proteus vulgaris, and Serratia marcescens (inhibiting greater than 90% of these isolates at a concentration of 0."1.28In vitro activity of sparfloxacin (CI-978; AT-4140) against clinical isolates from cancer patients. ( Bodey, GP; Ho, DH; LeBlanc, B; Messer, M; Nguyen, H; Rolston, KV, 1990)
"Forty six episodes of infection in 43 cancer patients were treated with oral ciprofloxacin at a dose of 750 mg every 8 h."1.28Oral ciprofloxacin therapy for infections in cancer patients. ( Bodey, GP; Cunningham, C; Haron, E; Holmes, F; Rolston, KV; Umsawasdi, T, 1989)
"One hundred forty-seven cancer patients were treated with intravenously administered ciprofloxacin, 200 mg every eight hours, as initial therapy for febrile episodes."1.28Intravenous ciprofloxacin for infections in cancer patients. ( Bodey, GP; Cunningham, C; Haron, E; Rolston, KV, 1989)
"Ciprofloxacin results to be an effective antibacterial agent in a high risk population."1.27Treatment of infections in non-neutropenic patients with cancer, AIDS, or renal transplant using ciprofloxacin. ( Bianchi, W; Maggiolo, F; Ohnmeiss, H, 1988)
"Sch 34343 was extremely active against beta-haemolytic streptococci (Lancefield groups A, B and G) with MIC90s ranging from 0."1.27In-vitro activity of Sch 34343, a new penam, against gram-positive isolates from cancer patients. ( Alderman, HC; Alvarez, ME; Bodey, GP; Ho, DH; Hoy, JF; Rolston, KV, 1986)
"Fleroxacin was also active against group JK-diphtheroids and Bacillus cereus."1.27In vitro activity of fleroxacin (Ro23-6240), a new fluorinated 4-quinolone against isolates from cancer patients. ( Bodey, GP; Ho, DH; LeBlanc, B; Rolston, K, 1988)

Research

Studies (98)

TimeframeStudies, this research(%)All Research%
pre-199014 (14.29)18.7374
1990's31 (31.63)18.2507
2000's21 (21.43)29.6817
2010's22 (22.45)24.3611
2020's10 (10.20)2.80

Authors

AuthorsStudies
Azéma, J2
Guidetti, B2
Dewelle, J1
Le Calve, B1
Mijatovic, T1
Korolyov, A2
Vaysse, J1
Malet-Martino, M2
Martino, R1
Kiss, R2
Antczak, C1
Shum, D1
Bassit, B1
Frattini, MG1
Li, Y3
de Stanchina, E1
Scheinberg, DA1
Djaballah, H1
Roques, C1
Constant, P1
Daffé, M1
Jahnsen, RD1
Sandberg-Schaal, A1
Vissing, KJ1
Nielsen, HM1
Frimodt-Møller, N1
Franzyk, H1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Venepally, V1
Prasad, RBN1
Poornachandra, Y1
Kumar, CG1
Jala, RCR1
Mohammed, HHH1
Abd El-Hafeez, AA1
Abbas, SH1
Abdelhafez, EMN1
Abuo-Rahma, GEA1
Febles, M1
Montalvão, S1
Crespín, GD1
Norte, M1
Padrón, JM1
Tammela, P1
Fernández, JJ1
Daranas, AH1
Pluta, K1
Jeleń, M1
Morak-Młodawska, B1
Zimecki, M1
Artym, J1
Kocięba, M1
Zaczyńska, E1
Chu, XM1
Wang, C1
Liu, W1
Liang, LL1
Gong, KK1
Zhao, CY1
Sun, KL1
Gao, F1
Zhang, X1
Wang, T1
Xiao, J1
Wang, R1
Hu, H1
Persoons, L1
Daelemans, D1
De Jonghe, S1
Luyten, W1
Krasniqi, B1
Dehaen, W1
Caldwell, L1
Bapat, A1
Drumright, LN1
Lambourne, J1
Jimenez-England, FG1
Aries, J1
Eccersley, L1
Hallam, S1
Montoto, S1
Oakervee, H1
Riches, J1
Agrawal, SG1
Suaifan, GARY1
Mohammed, AAM1
Alkhawaja, BA1
Matta-Chuquisapon, J1
Valencia-Bazalar, E1
Sevilla-Andrade, C1
Barrón-Pastor, HJ1
Ibrahim, UH1
Devnarain, N1
Mohammed, M1
Omolo, CA1
Gafar, MA1
Salih, M1
Pant, A1
Shunmugam, L1
Mocktar, C1
Khan, R1
Oh, JK1
Govender, T1
Alaaeldin, R3
Abdel-Rahman, IM3
Ali, FEM3
Bekhit, AA3
Elhamadany, EY3
Zhao, QL3
Cui, ZG3
Fathy, M3
Bauters, T1
Buyle, F1
Schelstraete, P1
Dhooge, C1
Forde, C1
McMullan, R1
Clarke, M1
Wilson, RH1
Plummer, R1
Grayson, M1
McDowell, C1
Agus, A1
Doran, A1
McAuley, DF1
Thomas, AL1
Barnes, RA1
Adams, R1
Chau, I1
Coyle, V1
Deng, Y1
Liu, SY1
Chua, SL1
Khoo, BL1
Wang, DY1
Yang, G1
van der Mei, HC1
Ren, Y1
Busscher, HJ1
Shi, L1
Sang, Q1
Li, H1
Williams, G1
Wu, H1
Zhu, LM1
Hamed, SM2
Aboshanab, KMA2
El-Mahallawy, HA2
Helmy, MM2
Ashour, MS2
Elkhatib, WF2
Lafaurie, M1
Gupta, P1
Gao, HL1
Ashar, YV1
Karadkhelkar, NM1
Yoganathan, S1
Chen, ZS1
Fu, Y1
Yang, Y1
Zhou, S1
Liu, Y1
Yuan, Y1
Li, S1
Li, C1
Borget, I1
Antoun, S1
Chachaty, E1
Gachot, B1
Alibay, A1
Di Palma, M1
Merad, M1
Srinivasan, A1
Seifried, S1
Zhu, L1
Srivastava, DK1
Flynn, PM1
Shenep, JL1
Bankowski, MJ1
Hayden, RT1
Sinkó, J1
Castro, W1
Navarro, M1
Biot, C1
Slavin, MA1
Thursky, KA1
Kern, WV3
Marchetti, O1
Drgona, L1
Akan, H1
Aoun, M1
Akova, M1
de Bock, R2
Paesmans, M2
Viscoli, C2
Calandra, T2
Schelenz, S1
Nwaka, D1
Hunter, PR1
Park, JR1
Coughlin, J1
Hawkins, D1
Friedman, DL1
Burns, JL1
Pendergrass, T1
Minenko, SV1
Dmitrieva, NV1
Chimishkian, KL1
Zhukov, NV1
Sokolova, EN1
Larionova, VB1
Ptushkin, VV1
Mullen, CA2
Cometta, A2
Kern, W1
Ammann, RA1
Escalante, CP1
Weiser, MA1
Manzullo, E2
Benjamin, R1
Rivera, E1
Lam, T1
Ho, V1
Valdres, R1
Lee, EL1
Badrina, N1
Fernandez, S1
DeJesus, Y1
Rolston, K3
Castagnola, E1
Haupt, R1
Micozzi, A2
Caviglia, I1
Testi, AM1
Giona, F1
Parodi, S1
Girmenia, C1
Paul, M2
Leibovici, L2
Bliziotis, IA1
Michalopoulos, A1
Kasiakou, SK1
Samonis, G1
Christodoulou, C1
Chrysanthopoulou, S1
Falagas, ME1
Nemes, G1
Heuser, Y1
Stolle, D1
Piroth, HD1
Nemes, P1
Beno, P1
Krcmery, V2
Demitrovicova, A1
Cullen, M1
Bucaneve, G2
Gafter-Gvili, A1
Fraser, A1
Sipsas, NV1
Kosmas, C1
Ziakas, PD1
Karabelis, A1
Vadiaka, M1
Skopelitis, E1
Kordossis, T1
Tsavaris, N1
Garcia, I1
Bodey, GP16
Fainstein, V1
Ho, DH12
LeBlanc, B11
Bennett, CL1
Smith, TJ1
George, SL1
Hillner, BE1
Fleishman, S1
Niell, HB1
Velasco, E1
Costa, MA1
Martins, CA1
Nucci, M1
Maiche, AG1
Muhonen, T1
Dholakia, N1
Rolston, KV16
Del Favero, A2
Menichetti, F2
Rubenstein, EB2
Benjamin, RS1
Loewy, J1
Escalante, C1
Hughes, P1
Moreland, B1
Fender, A1
Kennedy, K1
Lo, WK1
Hachem, R1
Raad, I2
Whimbey, E1
Katz, R1
Tarrand, J1
Libshitz, H1
Styler, MJ1
Crilley, P1
Biggs, J1
Moul, J1
Copelan, E1
Topolsky, D1
Avalos, B1
Penza, S1
Sabol, P1
Downs, K1
Szer, J1
Brodsky, I1
Marks, DI1
Meisenberg, B1
Gollard, R1
Brehm, T1
McMillan, R1
Miller, W1
Freifeld, A2
Pizzo, P1
Garcia, R1
Hidalgo, M3
Hornedo, J3
Lumbreras, C3
Trigo, JM1
Gómez, C2
Perea, S3
Ruiz, A1
Hitt, R1
Cortés-Funes, H3
Streeter, H1
Dvorak, T1
Murphy, M1
Brown, AE2
Sepkowitz, KA1
Bernard, EM1
Kiehn, TE1
Armstrong, D1
Salazar, R2
Solá, C2
Maroto, P1
Tabernero, JM1
Brunet, J1
Verger, G1
Valentí, V2
Cancelas, JA1
Ojeda, B1
Mendoza, L1
Rodríguez, M2
Montesinos, J1
López-López, JJ1
Minotti, V1
Gentile, G1
Iori, AP1
Cavicchi, F1
Barbabietola, G1
Landonio, G1
Martino, P1
Petropoulos, D1
Roberts, WM1
Rytting, M1
Zipf, T1
Chan, KW1
Culbert, SJ1
Danielson, M1
Jeha, SS1
Kuttesch, JF1
Marchigiani, D1
Walsh, T1
Chanock, S1
Lewis, L1
Hiemenz, J1
Hiemenz, S1
Hicks, JE1
Gill, V1
Steinberg, SM1
Pizzo, PA1
Langenaeken, J1
Gaya, H2
Arcediano, A2
Ramos, MJ1
Folgueira, D1
Rodriguez-Noriega, A1
Antabli, BA1
Bross, P1
Siegel, RS1
Small, CD1
Tabbara, IA1
Petrilli, AS1
Dantas, LS1
Campos, MC1
Tanaka, C1
Ginani, VC1
Seber, A1
Stein, RB1
Lichtenstein, GR1
Aquino, VM1
Herrera, L1
Sandler, ES1
Buchanan, GR1
Gomez-Martin, C1
Paganini, H2
Rodriguez-Brieshcke, T1
Zubizarreta, P2
Latella, A1
Firpo, V1
Casimir, L1
Armada, A1
Fernández, C1
Cáceres, E1
Debbag, R1
Drusano, GL1
Meunier, F1
Zinner, SH1
Klastersky, J1
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Maggiolo, F1
Bianchi, W1
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Hoy, JF1
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Gooch, G1
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Fülle, HH1
Hellriegel, KP1
Hsu, KC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Oral Empirical Therapy of Fever in Low-Risk Neutropenic Cancer Patients: A Prospective, Double-Blind, Randomized, Multicenter Trial Comparing Monotherapy (Single Daily Dose Moxifloxacin) With Combination Therapy (Ciprofloxacin Plus Amoxicillin/Clavulanic [NCT00062231]351 participants (Actual)Interventional2002-04-30Terminated (stopped due to low accrual)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for ciprofloxacin and Benign Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Anti

2017
Quinoline and quinolone dimers and their biological activities: An overview.
    European journal of medicinal chemistry, 2019, Jan-01, Volume: 161

    Topics: Anti-Bacterial Agents; Antimalarials; Antineoplastic Agents; Bacteria; Dimerization; Humans; Neoplas

2019
Quinolone hybrids and their anti-cancer activities: An overview.
    European journal of medicinal chemistry, 2019, Mar-01, Volume: 165

    Topics: Animals; Antineoplastic Agents; Humans; Neoplasms; Quinolones; Structure-Activity Relationship

2019
Fluoroquinolones' Biological Activities against Laboratory Microbes and Cancer Cell Lines.
    Molecules (Basel, Switzerland), 2022, Mar-03, Volume: 27, Issue:5

    Topics: Anti-Bacterial Agents; Bacteria; Cell Line; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity T

2022
[Treatment and prevention of infections in cancer patients with neutropenia].
    Magyar onkologia, 2011, Volume: 55, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Bacterial In

2011
Medicinal potential of ciprofloxacin and its derivatives.
    Future medicinal chemistry, 2013, Volume: 5, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Ciprofloxacin; Humans; Malaria, Falciparu

2013
Ciprofloxacin in treatment of fever and neutropenia in pediatric cancer patients.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:12

    Topics: Ambulatory Care; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy Protocols; Bacterial I

2003
[Treatment with oral antibiotics of febrile neutropenia in onco-haematology. The experience of the EORTC antimicrobial group].
    Presse medicale (Paris, France : 1983), 2004, Mar-13, Volume: 33, Issue:5

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Bacterial Infections; Ceftazidi

2004
Ciprofloxacin vs an aminoglycoside in combination with a beta-lactam for the treatment of febrile neutropenia: a meta-analysis of randomized controlled trials.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Therapy, Combination; Feve

2005
Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions.
    Cancer, 2006, Oct-15, Volume: 107, Issue:8

    Topics: Acute Disease; Antibiotic Prophylaxis; Antineoplastic Agents; Bone Marrow Transplantation; Ciproflox

2006
Free-riding and the prisoner's dilemma: problems in funding economic analyses of phase III cancer clinical trials.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1995, Volume: 13, Issue:9

    Topics: Carcinoma, Non-Small-Cell Lung; Ciprofloxacin; Clinical Trials, Phase III as Topic; Cost-Benefit Ana

1995
Ciprofloxacin-induced nephrotoxicity in patients with cancer.
    Archives of internal medicine, 1993, May-24, Volume: 153, Issue:10

    Topics: Acute Kidney Injury; Aged; Ciprofloxacin; Female; Fever; Humans; Kidney; Male; Middle Aged; Neoplasm

1993
Complications after ileal pouch-anal anastomosis.
    Seminars in gastrointestinal disease, 2000, Volume: 11, Issue:1

    Topics: Anastomosis, Surgical; Ciprofloxacin; Colitis, Ulcerative; Crohn Disease; Humans; Male; Metronidazol

2000

Trials

19 trials available for ciprofloxacin and Benign Neoplasms

ArticleYear
Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis (the EASI-SWITCH trial): study protocol for a randomised controlled trial.
    Trials, 2020, May-27, Volume: 21, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; An

2020
Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectiou
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Mar-20, Volume: 31, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Ag

2013
Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients.
    Medical and pediatric oncology, 2003, Volume: 40, Issue:2

    Topics: Administration, Oral; Ambulatory Care; Amoxicillin; Antineoplastic Agents; Blood Cell Count; Child;

2003
[Benzylpenicillin efficacy for neutropenic infection prophylaxis in patients with cancer and postcytostatic neutropenia].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:7

    Topics: Adolescent; Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacterial I

2002
Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2004, Volume: 12, Issue:9

    Topics: Adolescent; Adult; Aged; Ambulatory Care; Ampicillin; Anti-Bacterial Agents; Cancer Care Facilities;

2004
Randomized trial comparing oral ciprofloxacin plus penicillin V with amikacin plus carbenicillin or ceftazidime for empirical treatment of febrile neutropenic cancer patients.
    American journal of clinical oncology, 1995, Volume: 18, Issue:5

    Topics: Administration, Oral; Adult; Amikacin; Carbenicillin; Ceftazidime; Ciprofloxacin; Costs and Cost Ana

1995
Granulocyte colony-stimulating factor (G-CSF) with or without a quinolone in the prevention of infection in cancer patients.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Ciprofloxacin; Female; Granulocyte

1993
Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer.
    Cancer, 1993, Jun-01, Volume: 71, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Ambulatory Care; Aztreonam; Bacteremia; Bacterial Inf

1993
Lack of ability of ciprofloxacin-rifampin prophylaxis to decrease infection-related morbidity in neutropenic patients given cytotoxic therapy and peripheral blood stem cell transplants.
    Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antineoplastic Com

1997
Domiciliary treatment of febrile episodes in cancer patients: a prospective randomized trial comparing oral versus parenteral empirical antibiotic treatment.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999, Volume: 7, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bacterial Infections; C

1999
Outpatient treatment of fever and neutropenia for low risk pediatric cancer patients.
    Cancer, 1999, Jul-01, Volume: 86, Issue:1

    Topics: Adolescent; Ambulatory Care; Antineoplastic Agents; Bacterial Infections; Ceftazidime; Cephalosporin

1999
A double-blind comparison of empirical oral and intravenous antibiotic therapy for low-risk febrile patients with neutropenia during cancer chemotherapy.
    The New England journal of medicine, 1999, Jul-29, Volume: 341, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Antineoplastic Ag

1999
Oral versus intravenous empirical antimicrobial therapy for fever in patients with granulocytopenia who are receiving cancer chemotherapy. International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Can
    The New England journal of medicine, 1999, Jul-29, Volume: 341, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Agranulocytosis; Amikacin; Amoxici

1999
Empiric antimicrobial therapy of febrile neutropenic patients undergoing haematopoietic stem cell transplantation.
    International journal of antimicrobial agents, 1999, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Bone Marrow Transplantation; C

1999
Oral ciprofloxacin vs. intravenous ceftriaxone administered in an outpatient setting for fever and neutropenia in low-risk pediatric oncology patients: randomized prospective trial.
    Medical and pediatric oncology, 2000, Volume: 34, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Anti-Infective Agents; Antineoplastic Agen

2000
Rifampin does not improve the efficacy of quinolone antibacterial prophylaxis in neutropenic cancer patients: results of a randomized clinical trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:10

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antineoplastic Age

2000
Oral ciprofloxacin in the management of children with cancer with lower risk febrile neutropenia.
    Cancer, 2001, Apr-15, Volume: 91, Issue:8

    Topics: Administration, Oral; Adolescent; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Antineopla

2001
Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with lymphomas and solid tumors. The European Organization for Research on Treatment of Cancer
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Amikacin; Bacterial Infections; Ciprofloxacin; Drug

1991
Prophylaxis of bacterial infections with ciprofloxacin in patients undergoing bone marrow transplantation.
    Transplantation, 1991, Volume: 51, Issue:3

    Topics: Adult; Bacterial Infections; Biological Availability; Bone Marrow Transplantation; Ciprofloxacin; Fe

1991

Other Studies

65 other studies available for ciprofloxacin and Benign Neoplasms

ArticleYear
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.
    Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Ciprofloxacin; Humans; Maximum

2009
Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase.
    Bioorganic & medicinal chemistry letters, 2011, Aug-01, Volume: 21, Issue:15

    Topics: Amidohydrolases; Animals; Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Drug Screening Assay

2011
Synthesis of lipophilic dimeric C-7/C-7-linked ciprofloxacin and C-6/C-6-linked levofloxacin derivatives. Versatile in vitro biological evaluations of monomeric and dimeric fluoroquinolone derivatives as potential antitumor, antibacterial or antimycobacte
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:12

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Cell Line, Tumor; Cipr

2011
Tailoring cytotoxicity of antimicrobial peptidomimetics with high activity against multidrug-resistant Escherichia coli.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Antineoplastic Agents; Cell Proliferation; C

2014
Synthesis of novel ethyl 1-ethyl-6-fluoro-7-(fatty amido)-1,4-dihydro-4-oxoquinoline-3-carboxylate derivatives and their biological evaluation.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: 4-Quinolones; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Bac

2016
New antiproliferative 7-(4-(N-substituted carbamoylmethyl)piperazin-1-yl) derivatives of ciprofloxacin induce cell cycle arrest at G2/M phase.
    Bioorganic & medicinal chemistry, 2016, 10-01, Volume: 24, Issue:19

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cel

2016
Synthesis and biological evaluation of crown ether acyl derivatives.
    Bioorganic & medicinal chemistry letters, 2016, 11-15, Volume: 26, Issue:22

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antineoplastic Agents; Candida albi

2016
Antibacterial and antitumoral properties of 1,2,3-triazolo fused triterpenes and their mechanism of inhibiting the proliferation of HL-60 cells.
    European journal of medicinal chemistry, 2021, Nov-15, Volume: 224

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Proliferation; HL-60 Cells; Humans; Molecular Str

2021
Cessation of Ciprofloxacin Prophylaxis in Hemato-Oncology Patients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022, 08-24, Volume: 75, Issue:1

    Topics: Antibiotic Prophylaxis; Ciprofloxacin; Humans; Neoplasms

2022
Phylogeny and antimicrobial resistance of extended-spectrum beta-lactamaseproducing Escherichia coli from hospitalized oncology patients in Perú
    Biomedica : revista del Instituto Nacional de Salud, 2022, 09-02, Volume: 42, Issue:3

    Topics: Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Cross-Sectional Studies; Drug Resistance, Bac

2022
Dual acting acid-cleavable self-assembling prodrug from hyaluronic acid and ciprofloxacin: A potential system for simultaneously targeting bacterial infections and cancer.
    International journal of biological macromolecules, 2022, Dec-01, Volume: 222, Issue:Pt A

    Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Drug Delivery Systems; Humans; Hyaluroni

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Dual Topoisomerase I/II Inhibition-Induced Apoptosis and Necro-Apoptosis in Cancer Cells by a Novel Ciprofloxacin Derivative via RIPK1/RIPK3/MLKL Activation.
    Molecules (Basel, Switzerland), 2022, Nov-17, Volume: 27, Issue:22

    Topics: Apoptosis; Ciprofloxacin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Molecular Docking

2022
Administration of ciprofloxacin through a nasogastric tube in pediatric oncology and stem cell transplantation patients.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2023, Volume: 29, Issue:2

    Topics: Child; Ciprofloxacin; Enteral Nutrition; Hematopoietic Stem Cell Transplantation; Humans; Intubation

2023
The effects of biofilms on tumor progression in a 3D cancer-biofilm microfluidic model.
    Biosensors & bioelectronics, 2021, May-15, Volume: 180

    Topics: Anti-Bacterial Agents; Biofilms; Biosensing Techniques; Ciprofloxacin; Microfluidics; Neoplasms; Uro

2021
Liposomes with Water as a pH-Responsive Functionality for Targeting of Acidic Tumor and Infection Sites.
    Angewandte Chemie (International ed. in English), 2021, 08-02, Volume: 60, Issue:32

    Topics: Acetates; Animals; Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Drug Carriers; Female; Fluorescen

2021
Core-shell poly(lactide-co-ε-caprolactone)-gelatin fiber scaffolds as pH-sensitive drug delivery systems.
    Journal of biomaterials applications, 2018, Volume: 32, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Cell Line; Cell Line, Tumor; Ciprofloxa

2018
Plasmid-Mediated Quinolone Resistance in Gram-Negative Pathogens Isolated from Cancer Patients in Egypt.
    Microbial drug resistance (Larchmont, N.Y.), 2018, Volume: 24, Issue:9

    Topics: Anti-Bacterial Agents; beta-Lactamases; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Egypt;

2018
Multiple mechanisms contributing to ciprofloxacin resistance among Gram negative bacteria causing infections to cancer patients.
    Scientific reports, 2018, 08-16, Volume: 8, Issue:1

    Topics: Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; G

2018
[Febrile neutropenia: is ambulatory care possible]?
    La Revue du praticien, 2017, Volume: 67, Issue:2

    Topics: Administration, Oral; Ambulatory Care; Anti-Bacterial Agents; Ciprofloxacin; Febrile Neutropenia; Hu

2017
Ciprofloxacin Enhances the Chemosensitivity of Cancer Cells to ABCB1 Substrates.
    International journal of molecular sciences, 2019, Jan-11, Volume: 20, Issue:2

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cell Line, Tumor; Ciprofloxacin; Dose-Response Relati

2019
Ciprofloxacin containing Mannich base and its copper complex induce antitumor activity via different mechanism of action.
    International journal of oncology, 2014, Volume: 45, Issue:5

    Topics: Apoptosis; Cell Cycle; Cell Proliferation; Ciprofloxacin; Copper; Drug Screening Assays, Antitumor;

2014
[Modalities of management of cancer patients with febrile neutropenia in the oncology emergency unit of Gustave-Roussy and their related costs].
    Bulletin du cancer, 2014, Volume: 101, Issue:10

    Topics: Adult; Aged; Ambulatory Care; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents;

2014
Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus infections in children with cancer.
    Pediatric blood & cancer, 2009, Dec-15, Volume: 53, Issue:7

    Topics: Adolescent; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; Bacterial Toxins; Child; Child, P

2009
Outpatient therapy for fever and neutropenia is safe but implementation is the key.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Mar-20, Volume: 31, Issue:9

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Ciprofloxacin; Female; Fev

2013
Longitudinal surveillance of bacteraemia in haematology and oncology patients at a UK cancer centre and the impact of ciprofloxacin use on antimicrobial resistance.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:6

    Topics: Anti-Bacterial Agents; Bacteremia; Cancer Care Facilities; Ciprofloxacin; Drug Resistance, Bacterial

2013
Outpatient, sequential, parenteral-oral antibiotic therapy for lower risk febrile neutropenia in children with malignant disease: a single-center, randomized, controlled trial in Argentina.
    Cancer, 2004, Apr-01, Volume: 100, Issue:7

    Topics: Anti-Bacterial Agents; Argentina; Ceftriaxone; Child; Ciprofloxacin; Humans; Neoplasms; Neutropenia;

2004
Differences in the proportions of fluoroquinolone-resistant Gram-negative bacteria isolated from bacteraemic children with cancer in two Italian centres.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:6

    Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Ceftazidime; Child; Ciprofloxacin; Drug Resistance, Mul

2005
[Bacterial infections in cancer patients].
    Krankenpflege Journal, 2005, Volume: 43, Issue:1-3

    Topics: Administration, Oral; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria

2005
Systematic reviews and meta-analysis of febrile neutropenia.
    Mayo Clinic proceedings, 2005, Volume: 80, Issue:9

    Topics: Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; Drug Therapy, Combination; Feve

2005
Ciprofloxacin treatment of acute infections in immunocompromised host.
    Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl

    Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Clinical Tri

1989
Bacteraemia in cancer patients caused by colistin-resistant Gram-negative bacilli after previous exposure to ciprofloxacin and/or colistin.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2006, Volume: 12, Issue:5

    Topics: Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Colistin; Drug Resistance, Bacterial; Gram-Negativ

2006
Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate.
    Scandinavian journal of infectious diseases, 2007, Volume: 39, Issue:9

    Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Amoxicillin-Potassium Clavulanate Combination; A

2007
In vitro activity of WIN 49375 compared with those of other antibiotics in isolates from cancer patients.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Mic

1984
Susceptibilities of bacterial isolates from patients with cancer to levofloxacin and other quinolones.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:4

    Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Gram-Negative Bacteria; Gram-P

1994
The new fluorinated quinolones for antimicrobial prophylaxis in neutropenic cancer patients.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A Suppl 1

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Ciprofloxacin; Drug Therapy, Combination; Gram-Negativ

1993
Cutaneous and pulmonary infections caused by Mycobacterium vaccae.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23, Issue:1

    Topics: Aged; Animals; Anti-Bacterial Agents; Cattle; Ciprofloxacin; Humans; Male; Middle Aged; Minocycline;

1996
Hepatic dysfunction following busulfan and cyclophosphamide myeloablation: a retrospective, multicenter analysis.
    Bone marrow transplantation, 1996, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bone Marrow Transplantation; Busulfan; Child; Child,

1996
Prophylactic antibiotics eliminate bacteremia and allow safe outpatient management following high-dose chemotherapy and autologous stem cell rescue.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1996, Volume: 4, Issue:5

    Topics: Ambulatory Care; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Combined Chemotherapy

1996
Use of fluoroquinolones for empirical management of febrile neutropenia in pediatric cancer patients.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:1

    Topics: Administration, Oral; Anti-Infective Agents; Child; Ciprofloxacin; Fever of Unknown Origin; Humans;

1997
In vitro study of the potential role of quinupristin/dalfopristin in the treatment of catheter-related staphylococcal infections.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Bacteremia; Catheterizati

1996
In-vitro activity of trovafloxacin against clinical bacterial isolates from patients with cancer.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 39 Suppl B

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacter

1997
Fluoroquinolone prophylaxis for the prevention of bacterial infections in patients with cancer--is it justified?
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Drug Therapy; Ent

1997
Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation.
    Bone marrow transplantation, 1999, Volume: 23, Issue:1

    Topics: Acyclovir; Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Antineoplastic Combined Chem

1999
Incidence and clinical impact of fluoroquinolone-resistant Escherichia coli in the faecal flora of cancer patients treated with high dose chemotherapy and ciprofloxacin prophylaxis.
    The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:1

    Topics: Adult; Anti-Infective Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Bacteremia; Ciprofloxac

1999
Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer.
    Cancer, 2000, Apr-01, Volume: 88, Issue:7

    Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Anti-Infective Agents; Blood Cell Count; C

2000
Assessment and treatment of low-risk febrile neutropenic (LRFN) pediatric patients with cancer.
    Medical and pediatric oncology, 2002, Volume: 38, Issue:4

    Topics: Anti-Infective Agents; Ceftriaxone; Cephalosporins; Child; Ciprofloxacin; Fever; Humans; Neoplasms;

2002
Optimal sampling theory and population modelling: application to determination of the influence of the microgravity environment on drug distribution and elimination.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:10

    Topics: Bayes Theorem; Ceftazidime; Chromatography, High Pressure Liquid; Ciprofloxacin; Cystic Fibrosis; Fe

1991
In vitro activity of cefpodoxime against bacterial isolates obtained from patients with cancer.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:7

    Topics: Bacteria; Bacterial Infections; Cefpodoxime; Ceftizoxime; Ciprofloxacin; Humans; Microbial Sensitivi

1991
[Ciprofloxacin in the treatment of infections in oncology patients].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1990, Volume: 35, Issue:11

    Topics: Administration, Oral; Bacteria, Aerobic; Bacterial Infections; Ciprofloxacin; Drug Resistance, Micro

1990
In vitro activity of sparfloxacin (CI-978; AT-4140) against clinical isolates from cancer patients.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:11

    Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fleroxacin; Fluoroquinolones;

1990
In vitro activity of PD127,391, a new quinolone against bacterial isolates from cancer patients.
    Chemotherapy, 1990, Volume: 36, Issue:5

    Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Bacter

1990
In-vitro activity of PD 117 596, a new quinolone, against bacterial isolates from cancer patients.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:1

    Topics: Anti-Infective Agents; Bacteria; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Gram-Negativ

1990
[Peroral ciprofloxacin in the therapy of infections in oncology patients].
    Casopis lekaru ceskych, 1990, Oct-19, Volume: 129, Issue:42

    Topics: Adolescent; Adult; Aged; Bacterial Infections; Ciprofloxacin; Female; Humans; Immune Tolerance; Male

1990
Oral ciprofloxacin therapy for infections in cancer patients.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 24, Issue:6

    Topics: Adult; Aged; Bacterial Infections; Ciprofloxacin; Female; Humans; Male; Microbial Sensitivity Tests;

1989
Intravenous ciprofloxacin for infections in cancer patients.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Female; Humans; Infusions, Intraveno

1989
Treatment of sepsis in patients with neoplastic diseases with intravenous ciprofloxacin.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adult; Aged; Ciprofloxacin; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male;

1989
Survey of antibiotic susceptibility among gram-negative bacilli at a cancer hospital.
    The American journal of medicine, 1988, Jul-25, Volume: 85, Issue:1A

    Topics: Anti-Bacterial Agents; Aztreonam; Cefoperazone; Ceftazidime; Ciprofloxacin; Gram-Negative Bacteria;

1988
Treatment of infections in non-neutropenic patients with cancer, AIDS, or renal transplant using ciprofloxacin.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1988, Volume: 7, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Bacterial Infections; Ciprofloxa

1988
In-vitro activity of Sch 34343, a new penam, against gram-positive isolates from cancer patients.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 18, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Ciprofloxacin; Fluoroquinolones;

1986
Comparative in vitro activity of the new difluoro-quinolone temafloxacin (A-62254) against bacterial isolates from cancer patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1988, Volume: 7, Issue:5

    Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Humans; Microb

1988
In vitro activity of fleroxacin (Ro23-6240), a new fluorinated 4-quinolone against isolates from cancer patients.
    Chemotherapy, 1988, Volume: 34, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Enoxacin; Fleroxacin; Fluoroquinolones; Gram-Negative Bacteria

1988
Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin.
    Onkologie, 1987, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Agents; Bacterial Infections; Ciprof

1987
In vitro evaluation of difloxacin (A-56619), A-56620, and other 4-quinolones against isolates from cancer patients.
    Chemotherapy, 1987, Volume: 33, Issue:6

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Evaluation, Preclinical; Fluoroquinolones; Gram-Negative

1987
In-vitro activity of cefpirome (HR-810), WIN-49375, BMY-28142 and other antibiotics against nosocomially important isolates from cancer patients.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:4

    Topics: Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Ciprofloxacin; Cross Infection; Fluoroqu

1986
In vitro evaluation of S-25930 and S-25932, two new quinolones, against aerobic gram-negative isolates from cancer patients.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Enoxacin; Fluoroquinolones; Gram-Negativ

1987