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ciprofloxacin and Arthropathies

ciprofloxacin has been researched along with Arthropathies in 34 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"To report a case of possible ciprofloxacin-induced arthropathy in an adult patient with cystic fibrosis (CF)."7.68Arthropathy secondary to ciprofloxacin in an adult cystic fibrosis patient. ( Pleasants, RA; Samuelson, WM; Whitaker, MS, 1993)
"Food and Drug Administration regulations state that ciprofloxacin hydrochloride may cause arthropathies."3.70Ciprofloxacin as a therapeutic modality in pediatric burn wound infections: efficacious or contraindicated? ( Desai, M; Edgar, P; Heggers, JP; Herndon, DN; John, SD; Klein, GL; Villarreal, C; Wolf, S, 1998)
"To report a case of possible ciprofloxacin-induced arthropathy in an adult patient with cystic fibrosis (CF)."3.68Arthropathy secondary to ciprofloxacin in an adult cystic fibrosis patient. ( Pleasants, RA; Samuelson, WM; Whitaker, MS, 1993)
"To determine the safety of ciprofloxacin in paediatric patients in relation to arthropathy, any other adverse events (AEs) and drug interactions."2.47Ciprofloxacin safety in paediatrics: a systematic review. ( Adefurin, A; Choonara, I; Jacqz-Aigrain, E; Sammons, H, 2011)
"5 and 6 h after dosing and the drug was still detectable in plasma 48 h after dosing (0."1.30Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics. ( Förster, C; Günther, T; Lozo, E; Merker, HJ; Schwabe, R; Stahlmann, R; Vormann, J; Zippel, U, 1997)
"2."1.30The comparative arthropathy of fluoroquinolones in dogs. ( Hashimoto, K; Minami, T; Owen, K; Takizawa, T; Yamashita, S, 1999)
"Ciprofloxacin use can cause an acute reversible arthropathy, but in this study there is no evidence that its use can cause a delayed arthropathy or any permanent joint damage."1.29Ciprofloxacin use: acute arthropathy and long-term follow up. ( Karande, S; Kshirsagar, NA, 1996)
"Ciprofloxacin was also studied for its potential to act as an abortifacient when given orally or parenterally to cynomolgus monkeys."1.28Ciprofloxacin: toxicologic evaluation of additional safety data. ( Schluter, G, 1989)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.76)18.7374
1990's15 (44.12)18.2507
2000's10 (29.41)29.6817
2010's3 (8.82)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Bartolomé-Álvarez, J1
Solves-Ferriz, V1
Gómez-Junyent, J1
Rigo-Bonnin, R1
Benavent, E1
Soldevila, L1
Padullés, A1
Cabo, X1
Tubau, F1
Ariza, J1
Murillo, O1
Fuster, D1
Soriano, A1
Garcia, S1
Piera, C1
Suades, J1
Rodríguez, D1
Martinez, JC1
Mensa, J1
Campos, F1
Pons, F1
Adefurin, A1
Sammons, H1
Jacqz-Aigrain, E1
Choonara, I1
Malamitsi, J1
Papadopoulos, A1
Vezyrgianni, A1
Dalianis, K1
Boutsikou, M1
Giamarellou, H1
Nagai, A1
Miyazaki, M1
Morita, T1
Furubo, S1
Kizawa, K1
Fukumoto, H1
Sanzen, T1
Hayakawa, H1
Kawamura, Y1
Postnikov, SS1
Semykin, SIu1
Nazhimov, VP1
Novichkova, GA1
Sarda, L1
Crémieux, AC1
Lebellec, Y1
Meulemans, A1
Lebtahi, R1
Hayem, G1
Génin, R1
Delahaye, N1
Huten, D1
Le Guludec, D1
von Keutz, E1
Rühl-Fehlert, C1
Drommer, W1
Rosenbruch, M1
Britton, KE2
Das, SS1
Solanki, KK1
Legout, L1
Senneville, E1
Stern, R1
Yazdanpanah, Y1
Savage, C1
Roussel-Delvalez, M1
Rosele, B1
Migaud, H1
Mouton, Y1
Arda, B1
Sipahi, OR1
Yamazhan, T1
Emircan, I1
Aksu, K1
Ulusoy, S1
Camp, KA1
Miyagi, SL1
Schroeder, DJ1
Castera, L1
Pauwels, A1
Haettich, B1
Debenes, B1
Lévy, VG1
Orenstein, DM1
Pattishall, EN1
Noyes, BE1
Kurland, G1
Hartigan, ER1
Yu, VL1
Samuelson, WM1
Pleasants, RA1
Whitaker, MS1
Linseman, DA1
Hampton, LA1
Branstetter, DG1
Redmond, AO1
Karande, S1
Kshirsagar, NA1
Förster, C1
Schwabe, R1
Lozo, E1
Zippel, U1
Vormann, J1
Günther, T1
Merker, HJ1
Stahlmann, R1
Salam, MA1
Dhar, U1
Khan, WA1
Bennish, ML1
Heggers, JP1
Villarreal, C1
Edgar, P1
Wolf, S1
Klein, GL1
John, SD1
Desai, M1
Herndon, DN1
Takizawa, T1
Hashimoto, K1
Minami, T1
Yamashita, S1
Owen, K1
Iakovlev, VP1
Segers, B1
Olamazadeh, S1
Thirion, M1
Lambert, J1
Sonmezoglu, K1
Sonmezoglu, M1
Halac, M1
Akgün, I1
Türkmen, C1
Onsel, C1
Kanmaz, B1
Solanki, K1
Uslu, I1
Gulati, S1
Marwaha, RK1
Schaad, UB1
Stoupis, C1
Wedgwood, J1
Tschaeppeler, H1
Vock, P1
Fulton, B1
Moore, LL1
Schluter, G1
Jawad, AS1
Alfaham, M1
Holt, ME1
Goodchild, MC1
Greenberg, RN1
Kennedy, DJ1
Reilly, PM1
Luppen, KL1
Weinandt, WJ1
Bollinger, MR1
Aguirre, F1
Kodesch, F1
Saeed, AM1

Reviews

3 reviews available for ciprofloxacin and Arthropathies

ArticleYear
Ciprofloxacin safety in paediatrics: a systematic review.
    Archives of disease in childhood, 2011, Volume: 96, Issue:9

    Topics: Adolescent; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Child; Child, Preschool; Ciprofloxacin

2011
Potential quinolone-induced cartilage toxicity in children.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:3

    Topics: Anti-Infective Agents; Cartilage; Child; Child, Preschool; Ciprofloxacin; Clinical Trials as Topic;

1994
[Use of ciprofloxacin in the treatment and prevention of surgical infections].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1999, Volume: 44, Issue:7

    Topics: Anti-Infective Agents; Bacterial Infections; Bone Diseases, Infectious; Ciprofloxacin; Humans; Joint

1999

Trials

4 trials available for ciprofloxacin and Arthropathies

ArticleYear
Usefulness of 99mTc-ciprofloxacin scintigraphy in the diagnosis of prosthetic joint infections.
    Nuclear medicine communications, 2011, Volume: 32, Issue:1

    Topics: Aged; Arthroplasty; Ciprofloxacin; Female; Humans; Joint Diseases; Male; Organotechnetium Compounds;

2011
[On fluoroquinolones treatment safety in children (clinical, morphological and catamnesis data)].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2002, Volume: 47, Issue:9

    Topics: Adolescent; Age Factors; Anemia, Aplastic; Anti-Infective Agents; Body Height; Cartilage; Child; Chi

2002
Inability of 99mTc-ciprofloxacin scintigraphy to discriminate between septic and sterile osteoarticular diseases.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:6

    Topics: Adult; Aged; Arthritis, Infectious; Bone Diseases; Ciprofloxacin; Diagnosis, Differential; False Pos

2003
Randomised comparison of ciprofloxacin suspension and pivmecillinam for childhood shigellosis.
    Lancet (London, England), 1998, Aug-15, Volume: 352, Issue:9127

    Topics: Adolescent; Amdinocillin Pivoxil; Anti-Infective Agents; Arthralgia; Child; Child, Preschool; Ciprof

1998

Other Studies

27 other studies available for ciprofloxacin and Arthropathies

ArticleYear
[Increase in methicillin-resistant and ciprofloxacin-susceptible Staphylococcus aureus in osteoarticular, skin and soft tissue infections].
    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2020, Volume: 33, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Bacterial; Humans; Joint Diseases; Meth

2020
Efficacy and Therapeutic Drug Monitoring of Continuous Beta-Lactam Infusion for Osteoarticular Infections Caused by Fluoroquinolone-Resistant Pseudomonas aeruginosa: A Prospective Cohort Study.
    European journal of drug metabolism and pharmacokinetics, 2020, Volume: 45, Issue:5

    Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Bone Diseases, Infectious; Ciprofloxacin; Cohort Studies;

2020
The value of successive Infecton scans in assessing the presence of chronic bone and joint infection and in predicting its evolution after treatment and after a prolonged follow-up.
    Nuclear medicine communications, 2011, Volume: 32, Issue:11

    Topics: Adult; Aged; Arthrography; Blood Sedimentation; Bone and Bones; Bone Diseases, Infectious; C-Reactiv

2011
Comparative articular toxicity of garenoxacin, a novel quinolone antimicrobial agent, in juvenile beagle dogs.
    The Journal of toxicological sciences, 2002, Volume: 27, Issue:3

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Dogs; Dos

2002
Effects of ciprofloxacin on joint cartilage in immature dogs immediately after dosing and after a 5-month treatment-free period.
    Archives of toxicology, 2004, Volume: 78, Issue:7

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Cartilage, Articular; Ciprofloxacin; Dogs; Dos

2004
Ability of (99m)tc-ciprofloxacin scintigraphy to discriminate between septic and sterile osteoarticular diseases.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:5

    Topics: Arthritis, Infectious; Bone Diseases; Ciprofloxacin; Colloids; Diagnosis, Differential; Humans; Join

2004
Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2006, Volume: 12, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Diseases, Infectious; Cefepime; Cephalos

2006
Salmonella enteritidis related prosthetic joint infection.
    The West Indian medical journal, 2006, Volume: 55, Issue:6

    Topics: Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Female; Humans; Joint Diseases; Joint Prosthesis;

2006
[Arthropathy caused by fluoroquinolones in a patient after liver transplantation].
    La Revue de medecine interne, 1993, Volume: 14, Issue:5

    Topics: Adult; Ciprofloxacin; Humans; Joint Diseases; Knee Joint; Liver Transplantation; Male; Postoperative

1993
Safety of ciprofloxacin in children with cystic fibrosis.
    Clinical pediatrics, 1993, Volume: 32, Issue:8

    Topics: Administration, Oral; Adolescent; Alkaline Phosphatase; Child; Ciprofloxacin; Cystic Fibrosis; Drug

1993
Arthropathy secondary to ciprofloxacin in an adult cystic fibrosis patient.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:3

    Topics: Adult; Ciprofloxacin; Cystic Fibrosis; Humans; Joint Diseases; Male

1993
Quinolone-induced arthropathy in the neonatal mouse. Morphological analysis of articular lesions produced by pipemidic acid and ciprofloxacin.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 28, Issue:1

    Topics: Animals; Animals, Newborn; Anti-Infective Agents; Body Weight; Cartilage, Articular; Ciprofloxacin;

1995
Risk-benefit experience of ciprofloxacin use in pediatric patients in the United Kingdom.
    The Pediatric infectious disease journal, 1997, Volume: 16, Issue:1

    Topics: Acute Disease; Anti-Infective Agents; Child; Ciprofloxacin; Humans; Joint Diseases; Pseudomonas Infe

1997
Ciprofloxacin use: acute arthropathy and long-term follow up.
    Indian pediatrics, 1996, Volume: 33, Issue:11

    Topics: Acute Disease; Adverse Drug Reaction Reporting Systems; Anti-Infective Agents; Child; Child, Prescho

1996
Quinolone-induced arthropathy: exposure of magnesium-deficient aged rats or immature rats, mineral concentrations in target tissues and pharmacokinetics.
    Archives of toxicology, 1997, Volume: 72, Issue:1

    Topics: Age Factors; Animals; Anti-Infective Agents; Calcium; Cartilage; Ciprofloxacin; Contraindications; F

1997
Ciprofloxacin as a therapeutic modality in pediatric burn wound infections: efficacious or contraindicated?
    Archives of surgery (Chicago, Ill. : 1960), 1998, Volume: 133, Issue:11

    Topics: Adolescent; Age Factors; Anti-Infective Agents; Biopsy; Burns; Child; Child, Preschool; Ciprofloxaci

1998
The comparative arthropathy of fluoroquinolones in dogs.
    Human & experimental toxicology, 1999, Volume: 18, Issue:6

    Topics: Animals; Anti-Infective Agents; Body Weight; Ciprofloxacin; Dogs; Eating; Fluoroquinolones; Joint Di

1999
[A new method of scintigraphy].
    Revue medicale de Bruxelles, 2000, Volume: 21, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Diseases, Infectious; Ciprofloxacin; Female; Humans; Joint Dise

2000
Usefulness of 99mTc-ciprofloxacin (infecton) scan in diagnosis of chronic orthopedic infections: comparative study with 99mTc-HMPAO leukocyte scintigraphy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Bone and Bones; Child; Child, Preschool; Chron

2001
Post-exposure anthrax prophylaxis.
    The Medical letter on drugs and therapeutics, 2001, Oct-29, Volume: 43, Issue:1116-1117

    Topics: Abdominal Pain; Animals; Anthrax; Anthrax Vaccines; Anti-Bacterial Agents; Anti-Infective Agents; Ba

2001
Ciprofloxacin current status in pediatric practice.
    Indian pediatrics, 1992, Volume: 29, Issue:3

    Topics: Bacterial Infections; Child; Ciprofloxacin; Contraindications; Humans; Joint Diseases

1992
Clinical, radiologic and magnetic resonance monitoring for skeletal toxicity in pediatric patients with cystic fibrosis receiving a three-month course of ciprofloxacin.
    The Pediatric infectious disease journal, 1991, Volume: 10, Issue:10

    Topics: Adolescent; Adult; Cartilage, Articular; Child; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Join

1991
Comment: Ciprofloxacin excretion into breast milk.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:11

    Topics: Adolescent; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Joint Diseases; Lactation; Milk, Human

1990
Ciprofloxacin: toxicologic evaluation of additional safety data.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Abortion, Spontaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Ciprofloxacin; Dogs;

1989
Cystic fibrosis and drug-induced arthropathy.
    British journal of rheumatology, 1989, Volume: 28, Issue:2

    Topics: Adolescent; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Joint Diseases; Pseudomonas Infections

1989
Arthropathy in a patient with cystic fibrosis taking ciprofloxacin.
    British medical journal (Clinical research ed.), 1987, Sep-19, Volume: 295, Issue:6600

    Topics: Adolescent; Ciprofloxacin; Cystic Fibrosis; Female; Humans; Joint Diseases; Knee Joint; Pseudomonas

1987
Treatment of bone, joint, and soft-tissue infections with oral ciprofloxacin.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Cellulitis; Ciprofloxacin; Enterob

1987