Page last updated: 2024-10-25

ciprofloxacin and Aortic Dissection

ciprofloxacin has been researched along with Aortic Dissection in 5 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"Ciprofloxacin increases susceptibility to aortic dissection and rupture in a mouse model of moderate, sporadic AAD."7.88Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice. ( Azares, AR; Coselli, JS; LeMaire, SA; Luo, W; Ren, P; Shen, YH; Wang, Y; Zhang, C; Zhang, L, 2018)
"Ciprofloxacin accelerates aortic root enlargement and increases the incidence of aortic dissection and rupture in Marfan mice, partially by suppressing lysyl oxidase expression and further compromising the inherited defect in aortic elastic fibers."4.12Ciprofloxacin accelerates aortic enlargement and promotes dissection and rupture in Marfan mice. ( Barrish, JP; Coselli, JS; LeMaire, SA; Luo, W; Shen, YH; Zhang, L; Zhang, NS; Zhang, Q, 2022)
"Based on 3721 adverse event reports, all three fluoroquinolones are associated with aortic aneurysm, and levofloxacin is associated with aortic dissection."3.91Assessing fluoroquinolone-associated aortic aneurysm and dissection: Data mining of the public version of the FDA adverse event reporting system. ( Huang, H; Huang, J; Jia, Y; Meng, L; Qiu, F; Sun, S, 2019)
"Ciprofloxacin increases susceptibility to aortic dissection and rupture in a mouse model of moderate, sporadic AAD."3.88Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice. ( Azares, AR; Coselli, JS; LeMaire, SA; Luo, W; Ren, P; Shen, YH; Wang, Y; Zhang, C; Zhang, L, 2018)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
LeMaire, SA2
Zhang, L2
Zhang, NS1
Luo, W2
Barrish, JP1
Zhang, Q1
Coselli, JS2
Shen, YH2
Ren, P1
Azares, AR1
Wang, Y1
Zhang, C1
Upchurch, GR1
Goldstein, MR1
Mascitelli, L1
Meng, L1
Huang, J1
Jia, Y1
Huang, H1
Qiu, F1
Sun, S1

Other Studies

5 other studies available for ciprofloxacin and Aortic Dissection

ArticleYear
Ciprofloxacin accelerates aortic enlargement and promotes dissection and rupture in Marfan mice.
    The Journal of thoracic and cardiovascular surgery, 2022, Volume: 163, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Aorta; Aortic Aneurysm; Aortic Dissection; Aortic Rupture; Apoptosis

2022
Effect of Ciprofloxacin on Susceptibility to Aortic Dissection and Rupture in Mice.
    JAMA surgery, 2018, 09-01, Volume: 153, Issue:9

    Topics: Animals; Anti-Bacterial Agents; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Cells

2018
Evidence Against the Use of Fluoroquinolones in Patients With Aortic Pathology.
    JAMA surgery, 2018, 09-01, Volume: 153, Issue:9

    Topics: Animals; Anti-Infective Agents; Aorta; Aortic Dissection; Ciprofloxacin; Fluoroquinolones; Humans; M

2018
Fluoroquinolone Use and Concern About the Cerebral Vasculature.
    JAMA surgery, 2019, 03-01, Volume: 154, Issue:3

    Topics: Animals; Aortic Dissection; Ciprofloxacin; Fluoroquinolones; Mice; Microbial Sensitivity Tests

2019
Assessing fluoroquinolone-associated aortic aneurysm and dissection: Data mining of the public version of the FDA adverse event reporting system.
    International journal of clinical practice, 2019, Volume: 73, Issue:5

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aortic Aneurysm, Thoracic; Aortic

2019