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ciprofloxacin and Agranulocytosis

ciprofloxacin has been researched along with Agranulocytosis in 32 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"Fifty-three granulocytopenic patients were studied in a randomized trial comparing trimethoprim-sulfamethoxaxole (ST) alone with ST + ciprofloxacin (CPFX) for prevention of bacterial infections."9.08[Chemoprophylaxis of bacterial infections in granulocytopenic patients with new quinolone: a comparison of trimethoprim-sulfamethoxazole (ST) alone with ST plus ciprofloxacin]. ( Murase, T, 1995)
" The use of monotherapy with intravenous ciprofloxacin (200 to 300 mg every 12 h) was evaluated against combined therapy with piperacillin plus amikacin in febrile granulocytopenic patients with solid tumor or lymphoma."9.07Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with lymphomas and solid tumors. The European Organization for Research on Treatment of Cancer ( Calandra, T; Gaya, H; Glauser, M; Klastersky, J; Meunier, F; Viscoli, C; Zinner, SH, 1991)
"To assess the efficacy of ciprofloxacin in neutropenic patients, we conducted a randomized prospective trial comparing the combination of ciprofloxacin and netilmicin against piperacillin plus netilmicin as an empiric treatment of fever in cancer patients with neutropenia."9.06Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients. ( Anderson, H; Chan, CC; Oppenheim, BA; Scarffe, JH; Swindell, R, 1989)
"This study developed further clinical experience in using a single agent ("monotherapy") as empirical treatment for neutropenic patients with fever, and compared the safety and toxicity of two candidate agents, ceftazidime and ciprofloxacin."9.06A prospective, randomized comparison of ceftazidime and ciprofloxacin as initial empiric therapy in neutropenic patients with fever. ( Bayston, KF; Cohen, J; Want, S, 1989)
"Fifty-six patients receiving remission induction treatment for acute leukemia were studied in a randomized trial comparing ciprofloxacin with trimethoprim-sulfamethoxazole plus colistin for prevention of infections."9.06Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin. ( Dekker, AW; Rozenberg-Arska, M; Verhoef, J, 1987)
"Ciprofloxacin was compared to ciprofloxacin plus amoxicillin as antibacterial prophylaxis in 53 evaluable patients with neutropenic episodes, because an oral penicillin may help to decrease the incidence of gram-positive infections."6.67Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin vs ciprofloxacin plus amoxicillin. ( Bosi, A; Ciolli, S; Donnini, E; Fanci, R; Guidi, S; Leoni, F; Longo, G; Rossi Ferrini, P, 1993)
" Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0."5.35Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009)
"The optimal approach to reduce bacterial infections in granulocytopenic patients is still controversial."5.28[Prevention of bacterial infections using ciprofloxacin in granulocytopenic patients with cancer]. ( Gerain, J; Leleux, A; Libert, J; Meunier, F; Snoeck, R, 1989)
"In low-risk patients with cancer who have fever and granulocytopenia, oral therapy with ciprofloxacin plus amoxicillin-clavulanate is as effective as intravenous therapy."5.09Oral versus intravenous empirical antimicrobial therapy for fever in patients with granulocytopenia who are receiving cancer chemotherapy. International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Can ( Cometta, A; De Bock, R; Gaya, H; Kern, WV; Langenaeken, J; Paesmans, M, 1999)
"Fifty-three granulocytopenic patients were studied in a randomized trial comparing trimethoprim-sulfamethoxaxole (ST) alone with ST + ciprofloxacin (CPFX) for prevention of bacterial infections."5.08[Chemoprophylaxis of bacterial infections in granulocytopenic patients with new quinolone: a comparison of trimethoprim-sulfamethoxazole (ST) alone with ST plus ciprofloxacin]. ( Murase, T, 1995)
" The use of monotherapy with intravenous ciprofloxacin (200 to 300 mg every 12 h) was evaluated against combined therapy with piperacillin plus amikacin in febrile granulocytopenic patients with solid tumor or lymphoma."5.07Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with lymphomas and solid tumors. The European Organization for Research on Treatment of Cancer ( Calandra, T; Gaya, H; Glauser, M; Klastersky, J; Meunier, F; Viscoli, C; Zinner, SH, 1991)
"To assess the efficacy of ciprofloxacin in neutropenic patients, we conducted a randomized prospective trial comparing the combination of ciprofloxacin and netilmicin against piperacillin plus netilmicin as an empiric treatment of fever in cancer patients with neutropenia."5.06Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients. ( Anderson, H; Chan, CC; Oppenheim, BA; Scarffe, JH; Swindell, R, 1989)
"This study developed further clinical experience in using a single agent ("monotherapy") as empirical treatment for neutropenic patients with fever, and compared the safety and toxicity of two candidate agents, ceftazidime and ciprofloxacin."5.06A prospective, randomized comparison of ceftazidime and ciprofloxacin as initial empiric therapy in neutropenic patients with fever. ( Bayston, KF; Cohen, J; Want, S, 1989)
"In a multicenter, randomized clinical trial, the efficacy of ciprofloxacin plus azlocillin was compared with that of a standard regimen of ceftazidime plus amikacin for the initial empiric treatment of fever in neutropenic cancer patients."5.06Multicenter, randomized trial of ciprofloxacin plus azlocillin versus ceftazidime plus amikacin for empiric treatment of febrile neutropenic patients. ( Arnow, P; Edlin, B; Flaherty, JP; George, D; O'Keefe, P; Waitley, D; Weinstein, RA, 1989)
"Fifty-six patients receiving remission induction treatment for acute leukemia were studied in a randomized trial comparing ciprofloxacin with trimethoprim-sulfamethoxazole plus colistin for prevention of infections."5.06Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin. ( Dekker, AW; Rozenberg-Arska, M; Verhoef, J, 1987)
"Forty-six episodes of fever in 34 patients with neutropenia and haematological malignancy were treated empirically with a combination of ciprofloxacin and vancomycin."3.67A clinical, microbiological and pharmacokinetic study of ciprofloxacin plus vancomycin as initial therapy of febrile episodes in neutropenic patients. ( Farrell, ID; Geddes, AM; Leyland, MJ; Smith, GM, 1988)
"Twenty-four episodes of fever in neutropenic patients with haematological malignancy were treated with ciprofloxacin."3.67Preliminary evaluation of ciprofloxacin, a new 4-quinolone antibiotic, in the treatment of febrile neutropenic patients. ( Farrell, ID; Geddes, AM; Leyland, MJ; Smith, GM, 1986)
"Ciprofloxacin was therefore superior to the other two fluoroquinolones in preventing infections due to Gram-negative bacteria in this population of neutropenic patients."2.67Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies. ( Accorsi, P; Betti, S; D'Antonio, D; Dell'Isola, M; Favalli, C; Fioritoni, G; Iacone, A; Parruti, G; Piccolomini, R; Quaglietta, AM, 1994)
"Ciprofloxacin was compared to ciprofloxacin plus amoxicillin as antibacterial prophylaxis in 53 evaluable patients with neutropenic episodes, because an oral penicillin may help to decrease the incidence of gram-positive infections."2.67Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin vs ciprofloxacin plus amoxicillin. ( Bosi, A; Ciolli, S; Donnini, E; Fanci, R; Guidi, S; Leoni, F; Longo, G; Rossi Ferrini, P, 1993)
" Serious adverse reactions reported with ciprofloxacin are rare with an incidence of 0."1.35Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin. ( Ruxana, K; Upadya, GM, 2009)
"We report a case of agranulocytosis which developed 3 weeks after onset of acute hepatitis B in an HIV-positive patient."1.31[Agranulocytosis in acute hepatitis B in an HIV seropositive patient]. ( Brazille, P; Coutant-Perronne, V; Malkin, JE; Raguin, G, 2000)
"The optimal approach to reduce bacterial infections in granulocytopenic patients is still controversial."1.28[Prevention of bacterial infections using ciprofloxacin in granulocytopenic patients with cancer]. ( Gerain, J; Leleux, A; Libert, J; Meunier, F; Snoeck, R, 1989)
"Ciprofloxacin was studied in vitro and in an experimental thigh infection model in mice to evaluate its efficacy against Pseudomonas aeruginosa in comparison with that of tobramycin."1.27The activity of ciprofloxacin against Pseudomonas aeruginosa in normal and granulocytopenic mice. ( Hoogeterp, JJ; Mattie, H; Terporten, P, 1987)
"Ciprofloxacin was studied in vitro and in an experimental thigh infection model in mice to evaluate its efficacy against Pseudomonas aeruginosa in comparison with that of tobramycin."1.27The relative efficacies of tobramycin and ciprofloxacin against Pseudomonas aeruginosa in vitro and in normal and granulocytopenic mice. ( Hoogeterp, JJ; Mattie, H; Terporten, P, 1988)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199019 (59.38)18.7374
1990's10 (31.25)18.2507
2000's3 (9.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Upadya, GM1
Ruxana, K1
Murase, T1
D'Antonio, D2
Piccolomini, R1
Iacone, A1
Fioritoni, G1
Parruti, G1
Betti, S1
Quaglietta, AM1
Accorsi, P1
Dell'Isola, M1
Favalli, C1
Fanci, R1
Leoni, F1
Bosi, A1
Guidi, S1
Ciolli, S1
Longo, G1
Donnini, E1
Rossi Ferrini, P1
Kern, WV1
Cometta, A1
De Bock, R1
Langenaeken, J1
Paesmans, M1
Gaya, H2
Cambon, S1
Rossi, P1
Miliani, Y1
Arnaud, S1
Albanèse, J1
Brazille, P1
Coutant-Perronne, V1
Malkin, JE1
Raguin, G1
Giamarellou, H1
Bassaris, HP1
Petrikkos, G1
Busch, W1
Voulgarelis, M1
Antoniadou, A1
Grouzi, E1
Zoumbos, N1
Krcméry, V1
Fuchsberger, P1
Trupl, J1
Sufliarsky, J1
Spanik, S1
Koza, I1
Kusenda, Z1
Korec, S1
Svec, J1
Durkovic, P1
Donnelly, JP2
Maschmeyer, G1
Daenen, S1
Meunier, F2
Zinner, SH1
Calandra, T1
Viscoli, C1
Klastersky, J1
Glauser, M1
Opal, SM1
Cross, AS1
Kelly, NM1
Sadoff, JC1
Bodmer, MW1
Palardy, JE1
Victor, GH1
Dekker, AW2
Rozenberg-Arska, M2
Verdonck, LF1
Del Favero, A1
Martino, P1
Bucaneve, G1
Micozzi, A1
Minetti, B1
Ricci, P1
Landonio, G1
Montillo, M1
Malleo, C1
Kelsey, SM1
Wood, ME1
Shaw, E1
Newland, AC1
Weers-Pothoff, G1
Novakova, IR1
Muytjens, HL1
Snoeck, R1
Gerain, J1
Leleux, A1
Libert, J1
Chan, CC1
Oppenheim, BA1
Anderson, H1
Swindell, R1
Scarffe, JH1
Bayston, KF1
Want, S1
Cohen, J1
Flaherty, JP1
Waitley, D1
Edlin, B1
George, D1
Arnow, P1
O'Keefe, P1
Weinstein, RA1
Hoogeterp, JJ3
Mattie, H3
Krul, AM1
Terporten, P3
van Furth, R1
Bendig, JW1
Kyle, PW1
Giangrande, PL1
Samson, DM1
Azadian, BS1
Mannan, P1
Kibbler, CC1
Noone, P1
Gordin, FM1
Hackbarth, CJ1
Scott, KG1
Sande, MA1
Trautmann, M1
Brückner, O1
Marre, R1
Hahn, H1
Dennig, D1
Fülle, HH1
Hellriegel, KP1
Smith, GM2
Leyland, MJ2
Farrell, ID2
Geddes, AM2
Verhoef, J1
Fu, KP1
Hetzel, N1
Gregory, FJ1
Hung, PP1

Trials

14 trials available for ciprofloxacin and Agranulocytosis

ArticleYear
[Chemoprophylaxis of bacterial infections in granulocytopenic patients with new quinolone: a comparison of trimethoprim-sulfamethoxazole (ST) alone with ST plus ciprofloxacin].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1995, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infect

1995
Comparison of ciprofloxacin, ofloxacin and pefloxacin for the prevention of the bacterial infection in neutropenic patients with haematological malignancies.
    The Journal of antimicrobial chemotherapy, 1994, Volume: 33, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Anti-Infective Agents; Bacteremia; Bacterial Infections; Ciprofloxacin

1994
Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin vs ciprofloxacin plus amoxicillin.
    Journal of chemotherapy (Florence, Italy), 1993, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Amoxicillin; Bacteria; Bacterial Infections; Ciprofloxacin

1993
Oral versus intravenous empirical antimicrobial therapy for fever in patients with granulocytopenia who are receiving cancer chemotherapy. International Antimicrobial Therapy Cooperative Group of the European Organization for Research and Treatment of Can
    The New England journal of medicine, 1999, Jul-29, Volume: 341, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Agranulocytosis; Amikacin; Amoxici

1999
Monotherapy with intravenous followed by oral high-dose ciprofloxacin versus combination therapy with ceftazidime plus amikacin as initial empiric therapy for granulocytopenic patients with fever.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:12

    Topics: Administration, Oral; Agranulocytosis; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefta

2000
Ciprofloxacin plus vancomycin versus ceftazidime plus gentamicin in the treatment of pneumonia in granulocytopenic patients with or without venous catheters. Short communication.
    Chemotherapy, 1992, Volume: 38, Issue:4

    Topics: Adult; Agranulocytosis; Bronchopneumonia; Catheterization; Ceftazidime; Ciprofloxacin; Drug Therapy,

1992
Selective oral antimicrobial prophylaxis for the prevention of infection in acute leukaemia-ciprofloxacin versus co-trimoxazole plus colistin. The EORTC-Gnotobiotic Project Group.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:4-5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Ciprofloxacin; Colistin; Drug Therap

1992
Prospective randomized evaluation of ciprofloxacin versus piperacillin plus amikacin for empiric antibiotic therapy of febrile granulocytopenic cancer patients with lymphomas and solid tumors. The European Organization for Research on Treatment of Cancer
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Amikacin; Bacterial Infections; Ciprofloxacin; Drug

1991
[Prophylaxis using quinolones in neutropenic patients. Preliminary results of a cooperative study by the Grupo Italiano Malattie Ematologiche maligne dell'adulto (GIMEMEA)].
    Haematologica, 1989, Volume: 74, Issue:5 Suppl

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Bone Marrow Transplantation; Ciproflox

1989
Intravenous ciprofloxacin as empirical treatment of febrile neutropenic patients.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adult; Agranulocytosis; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fe

1989
Randomized trial comparing ciprofloxacin plus netilmicin versus piperacillin plus netilmicin for empiric treatment of fever in neutropenic patients.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Bone Marrow Tr

1989
A prospective, randomized comparison of ceftazidime and ciprofloxacin as initial empiric therapy in neutropenic patients with fever.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adolescent; Adult; Agranulocytosis; Bacterial Infections; Ceftazidime; Ciprofloxacin; Female; Fever;

1989
Multicenter, randomized trial of ciprofloxacin plus azlocillin versus ceftazidime plus amikacin for empiric treatment of febrile neutropenic patients.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Amikacin; Azlocillin; Bacterial Infections; Ceftazi

1989
Infection prophylaxis in acute leukemia: a comparison of ciprofloxacin with trimethoprim-sulfamethoxazole and colistin.
    Annals of internal medicine, 1987, Volume: 106, Issue:1

    Topics: Acute Disease; Agranulocytosis; Bacterial Infections; Ciprofloxacin; Colistin; Drug Combinations; Dr

1987

Other Studies

18 other studies available for ciprofloxacin and Agranulocytosis

ArticleYear
Toxic epidermal necrolysis and agranulocytosis: rare adverse effects of ciprofloxacin.
    Indian journal of medical sciences, 2009, Volume: 63, Issue:10

    Topics: Administration, Oral; Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Ciproflo

2009
[Severe agranulocytosis induced by carbamazepine (Tegretol)].
    Annales francaises d'anesthesie et de reanimation, 1999, Volume: 18, Issue:5

    Topics: Acinetobacter Infections; Adult; Agranulocytosis; Analgesics, Non-Narcotic; Anti-Bacterial Agents; A

1999
[Agranulocytosis in acute hepatitis B in an HIV seropositive patient].
    Presse medicale (Paris, France : 1983), 2000, Mar-04, Volume: 29, Issue:8

    Topics: Acute Disease; Adult; Agranulocytosis; Anti-HIV Agents; Ciprofloxacin; Diagnosis, Differential; Drug

2000
Efficacy of a monoclonal antibody directed against tumor necrosis factor in protecting neutropenic rats from lethal infection with Pseudomonas aeruginosa.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:6

    Topics: Agranulocytosis; Animals; Antibodies, Monoclonal; Ciprofloxacin; Combined Modality Therapy; Disease

1990
Prevention of bacteremias caused by alpha-hemolytic streptococci by roxithromycin in patients treated with intensive cytotoxic treatment.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Acute Disease; Adult; Agranulocytosis; Amphotericin B; Antineoplastic Combined Chemotherapy Protocol

1990
Bacteraemia caused by Stomatococcus mucilaginosus in a granulocytopenic patient with acute lymphocytic leukaemia.
    The Netherlands journal of medicine, 1989, Volume: 35, Issue:3-4

    Topics: Adult; Agranulocytosis; Amsacrine; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Proto

1989
[Prevention of bacterial infections using ciprofloxacin in granulocytopenic patients with cancer].
    Revue medicale de Bruxelles, 1989, Volume: 10, Issue:10

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacterial Infections; Ciprofloxacin

1989
Comparison of in vivo and in vitro activities of antibiotics with different modes of action against a tolerant and a non-tolerant Staphylococcus aureus strain.
    Scandinavian journal of infectious diseases, 1989, Volume: 21, Issue:1

    Topics: Agranulocytosis; Animals; Ciprofloxacin; Drug Resistance, Microbial; Erythromycin; Mice; Penicillin

1989
Two neutropenic patients with multiple resistant Pseudomonas aeruginosa septicaemia treated with ciprofloxacin.
    Journal of the Royal Society of Medicine, 1987, Volume: 80, Issue:5

    Topics: Adolescent; Aged; Agranulocytosis; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Microbial;

1987
The activity of ciprofloxacin against Pseudomonas aeruginosa in normal and granulocytopenic mice.
    Pharmaceutisch weekblad. Scientific edition, 1987, Dec-11, Volume: 9 Suppl

    Topics: Agranulocytosis; Animals; Ciprofloxacin; Male; Mice; Microbial Sensitivity Tests; Pseudomonas aerugi

1987
The relative efficacies of tobramycin and ciprofloxacin against Pseudomonas aeruginosa in vitro and in normal and granulocytopenic mice.
    Infection, 1988, Volume: 16, Issue:1

    Topics: Agranulocytosis; Animals; Ciprofloxacin; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Tobra

1988
Activity of ciprofloxacin and colistin against Pseudomonas aeruginosa isolates from neutropenic patients: a possible approach to prophylaxis.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 22, Issue:6

    Topics: Agranulocytosis; Ciprofloxacin; Colistin; Drug Resistance, Microbial; Humans; Microbial Sensitivity

1988
Activities of pefloxacin and ciprofloxacin in experimentally induced Pseudomonas pneumonia in neutropenic guinea pigs.
    Antimicrobial agents and chemotherapy, 1985, Volume: 27, Issue:4

    Topics: Agranulocytosis; Animals; Anti-Bacterial Agents; Ciprofloxacin; Guinea Pigs; Half-Life; Microbial Se

1985
Comparative efficacy of ciprofloxacin, ceftazidime and gentamicin, given alone or in combination, in a model of experimental septicemia due to Klebsiella pneumoniae in neutropenic mice.
    Infection, 1988, Volume: 16, Issue:1

    Topics: Agranulocytosis; Animals; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combinat

1988
Chemoprophylaxis of bacterial infections in granulocytopenic patients with ciprofloxacin.
    Onkologie, 1987, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Antineoplastic Agents; Bacterial Infections; Ciprof

1987
A clinical, microbiological and pharmacokinetic study of ciprofloxacin plus vancomycin as initial therapy of febrile episodes in neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Ciprofloxacin; Drug Therapy, Combination; Fever; Humans; L

1988
Preliminary evaluation of ciprofloxacin, a new 4-quinolone antibiotic, in the treatment of febrile neutropenic patients.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 18 Suppl D

    Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Ciprofloxacin; Female; Fever; Half-Life; Humans;

1986
Therapeutic efficacy of cefpiramide-ciprofloxacin combination in experimental Pseudomonas infections in neutropenic mice.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:4

    Topics: Agranulocytosis; Animals; Cephalosporins; Ciprofloxacin; Cyclophosphamide; Drug Therapy, Combination

1987