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ciprofloxacin and Adverse Drug Event

ciprofloxacin has been researched along with Adverse Drug Event in 24 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"Fluoroquinolones reduce occurrence of fever in adult cancer patients who develop neutropenia, but there has been no randomized controlled trial in children, and there are only a few studies considering resistance in intestinal floral after ciprofloxacin has been used."9.17Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy. ( Chelae, S; Khwanna, T; Laoprasopwattana, K; Sujjanunt, T; Suwankeeree, P; Tunyapanit, W, 2013)
" We present a 56-year-old man with a history of hypertension, chronic kidney disease stage IIIa, recent exposure to ciprofloxacin who presented with acute kidney injury."8.02Atypical presentation of allergic interstitial nephritis likely induced by ciprofloxacin. ( Jim, B; Saad, P; Sekulic, M; Valdez Imbert, R, 2021)
"Ciprofloxacin (CIPRO) is a fluroquinolone class antibiotic used commonly for the treatment of various acute and chronic bacterial infections."6.72Ciprofloxacin-induced cutaneous adverse drug events: a systematic review of descriptive studies. ( Chhabra, M; Kashyap, A; Rajan, AK; Rashid, M; Sreenivasan, S, 2021)
"This report describes a new observation of hyperglycemia in a child with Type 1 diabetes after off-label use of otic ciprofloxacin/dexamethasone drops in the nasal passage and reviews previous reports of adverse endocrine effects from intranasal corticosteroids in pediatric patients."5.41Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects. ( April, MM; Ben-Dov, T; Yang, J, 2023)
"Fluoroquinolones reduce occurrence of fever in adult cancer patients who develop neutropenia, but there has been no randomized controlled trial in children, and there are only a few studies considering resistance in intestinal floral after ciprofloxacin has been used."5.17Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy. ( Chelae, S; Khwanna, T; Laoprasopwattana, K; Sujjanunt, T; Suwankeeree, P; Tunyapanit, W, 2013)
" We present a 56-year-old man with a history of hypertension, chronic kidney disease stage IIIa, recent exposure to ciprofloxacin who presented with acute kidney injury."4.02Atypical presentation of allergic interstitial nephritis likely induced by ciprofloxacin. ( Jim, B; Saad, P; Sekulic, M; Valdez Imbert, R, 2021)
"Based on 1422 cases of fluoroquinolone-associated hypersensitivity reactions and national drug utilization projections, we estimated risk of hypersensitivity reactions for moxifloxacin, ciprofloxacin, and levofloxacin."3.79US-based emergency department visits for fluoroquinolone-associated hypersensitivity reactions. ( Budnitz, DS; Jones, SC; Mehta, H; Sorbello, A, 2013)
"Ciprofloxacin (CIPRO) is a fluroquinolone class antibiotic used commonly for the treatment of various acute and chronic bacterial infections."2.72Ciprofloxacin-induced cutaneous adverse drug events: a systematic review of descriptive studies. ( Chhabra, M; Kashyap, A; Rajan, AK; Rashid, M; Sreenivasan, S, 2021)
"Potential drug-drug interactions (pDDIs) are described in various case reports, but few studies have evaluated the impact of specific combinations on a population level."1.48Analysis of Drug-Drug Interactions in Swiss Claims Data Using Tizanidine and Ciprofloxacin as a Prototypical Contraindicated Combination. ( Curkovic, I; Egbring, M; Jödicke, AM; Kullak-Ublick, GA; Neuer, T; Roos, M; Tomka, IT; Zellweger, U, 2018)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)
"5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects."1.32Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004)
" A few selected examples of potential drug-drug interactions and interventions instituted are presented in this paper."1.29Preventing potential drug interactions in community pharmacy. ( Lien, EJ; Lien, LL, 1994)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.33)18.2507
2000's4 (16.67)29.6817
2010's12 (50.00)24.3611
2020's6 (25.00)2.80

Authors

AuthorsStudies
Matthews, EJ1
Kruhlak, NL1
Weaver, JL1
Benz, RD1
Contrera, JF1
Mohamed, MS1
Kamel, MM1
Kassem, EM1
Abotaleb, N1
Abd El-Moez, SI1
Ahmed, MF1
Chen, M1
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W2
Ding, D1
Kelly, R1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Ben-Dov, T1
Yang, J1
April, MM1
Hartinger, JM1
Dvorackova, E1
Myslivecek, M1
Hruskova, Z1
Satny, M1
Zlatohlavek, L1
Krizova, J1
Sima, M1
Tesar, V1
Slanar, O1
Kashyap, A1
Sreenivasan, S1
Rajan, AK1
Rashid, M1
Chhabra, M1
Valdez Imbert, R1
Sekulic, M1
Saad, P1
Jim, B1
Rabbi, F1
Qayum, I1
Humayun, O1
Khan, MI1
Khan, UI1
Abdullah, HMA1
Huruba, M1
Farcas, A1
Leucuta, DC1
Bucsa, C1
Sipos, M1
Mogosan, C1
Jödicke, AM1
Curkovic, I1
Zellweger, U1
Tomka, IT1
Neuer, T1
Kullak-Ublick, GA1
Roos, M1
Egbring, M1
Mollica, AJ2
Grant, E1
Malik, A1
Claydon, M1
Friedman, ND1
Athan, E1
Hughes, AJ1
Khajehnoori, M1
McDonald, A1
Callan, P1
Rahdon, R1
O'Brien, DP1
Jones, SC1
Budnitz, DS1
Sorbello, A1
Mehta, H1
Hawke, KL1
McGuire, TM1
Ranmuthugala, G1
van Driel, ML1
Garbe, E1
Andersohn, F1
Bronder, E1
Klimpel, A1
Thomae, M1
Schrezenmeier, H1
Hildebrandt, M1
Späth-Schwalbe, E1
Grüneisen, A1
Mayer, B1
Salama, A1
Kurtal, H1
Laoprasopwattana, K1
Khwanna, T1
Suwankeeree, P1
Sujjanunt, T1
Tunyapanit, W1
Chelae, S1
Preskorn, SH1
Lien, LL1
Lien, EJ1
Bernstein, RM1
García Porrúa, C1
González Gay, MA1
Rivas, MJ1
Ramos Gudino, B1
Vogel, CU1
Peiter, A1
Feuring, M1
Wehling, M1

Reviews

3 reviews available for ciprofloxacin and Adverse Drug Event

ArticleYear
Off-Label Use of Ciprofloxacin/Dexamethasone Drops in the Pediatric Upper Airway: Case Presentation and Review of Adverse Effects.
    The Annals of otology, rhinology, and laryngology, 2023, Volume: 132, Issue:5

    Topics: Administration, Intranasal; Blood Glucose; Child; Ciprofloxacin; Dexamethasone; Diabetes Mellitus, T

2023
Ciprofloxacin-induced cutaneous adverse drug events: a systematic review of descriptive studies.
    Journal of basic and clinical physiology and pharmacology, 2021, Mar-16, Volume: 33, Issue:3

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Drug Eruptions; Drug-Related Side Effects and Adverse Reaction

2021
Drugs and toxins: fact and fancy.
    Current opinion in rheumatology, 1999, Volume: 11, Issue:1

    Topics: Anti-Infective Agents; Ciprofloxacin; Cyclosporine; Drug-Related Side Effects and Adverse Reactions;

1999

Trials

1 trial available for ciprofloxacin and Adverse Drug Event

ArticleYear
Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:3

    Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agen

2013

Other Studies

20 other studies available for ciprofloxacin and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru

2004
Novel 6,8-dibromo-4(3H)quinazolinone derivatives of anti-bacterial and anti-fungal activities.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:8

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacteria; Drug Design; Drug-Related Side Effects and Adver

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
The frequency of, and predisposing risk factors for, ciprofloxacin-induced neuro-psychiatric adverse drug reactions.
    Bratislavske lekarske listy, 2023, Volume: 124, Issue:10

    Topics: Aged; Ciprofloxacin; Disease Susceptibility; Drug-Related Side Effects and Adverse Reactions; Humans

2023
Atypical presentation of allergic interstitial nephritis likely induced by ciprofloxacin.
    BMJ case reports, 2021, Jun-24, Volume: 14, Issue:6

    Topics: Acute Kidney Injury; Ciprofloxacin; Drug-Related Side Effects and Adverse Reactions; Humans; Male; M

2021
Ciprofloxacin-Associated Pancytopenia: A Rare Side Effect of a Commonly Prescribed Medication.
    American journal of therapeutics, 2023, 05-01, Volume: 30, Issue:3

    Topics: Ciprofloxacin; Drug-Related Side Effects and Adverse Reactions; Humans; Iatrogenic Disease; Pancytop

2023
A VigiBase descriptive study of fluoroquinolone induced disabling and potentially permanent musculoskeletal and connective tissue disorders.
    Scientific reports, 2021, 07-13, Volume: 11, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Adverse Drug Reaction Reporting Systems; Arthralgia; Cip

2021
Analysis of Drug-Drug Interactions in Swiss Claims Data Using Tizanidine and Ciprofloxacin as a Prototypical Contraindicated Combination.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Clonidine; Cohort

2018
Ciprofloxacin-Induced Bullae of the Lower Extremity: A Case of a Fixed Drug Reaction.
    Journal of the American Podiatric Medical Association, 2019, Volume: 109, Issue:2

    Topics: Anti-Bacterial Agents; Blister; Ciprofloxacin; Drug-Related Side Effects and Adverse Reactions; Foot

2019
Mycobacterium ulcerans disease: experience with primary oral medical therapy in an Australian cohort.
    PLoS neglected tropical diseases, 2013, Volume: 7, Issue:7

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Australia; Buruli Ulcer; Ciprofloxacin; Cl

2013
US-based emergency department visits for fluoroquinolone-associated hypersensitivity reactions.
    Pharmacoepidemiology and drug safety, 2013, Volume: 22, Issue:10

    Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Ciprofloxacin; Drug-Related Side Effects and Adve

2013
What do consumers want to know about antibiotics? Analysis of a medicines call centre database.
    Family practice, 2016, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Australia; Child; Child, Preschool; Cip

2016
Drug induced immune haemolytic anaemia in the Berlin Case-Control Surveillance Study.
    British journal of haematology, 2011, Volume: 154, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; An

2011
Multiple medication use presenting as Parkinson's dementia complex: a message from Titanic.
    Journal of psychiatric practice, 2008, Volume: 14, Issue:1

    Topics: Aged; Anti-Infective Agents; Antiparkinson Agents; Antipsychotic Agents; Bacteriuria; Ciprofloxacin;

2008
Preventing potential drug interactions in community pharmacy.
    Journal of clinical pharmacy and therapeutics, 1994, Volume: 19, Issue:6

    Topics: Chelating Agents; Ciprofloxacin; Drug Interactions; Drug Therapy; Drug-Related Side Effects and Adve

1994
[Cutaneous vasculitis and drugs].
    Anales de medicina interna (Madrid, Spain : 1984), 2001, Volume: 18, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Drug-Related Side Effects and Adverse Reactions; Female; Human

2001
[Drug therapy in the old age. Drug effects in the elderly].
    MMW Fortschritte der Medizin, 2001, Dec-13, Volume: 143, Issue:51-52

    Topics: Age Factors; Aged; Aged, 80 and over; Algorithms; Anti-Infective Agents; Anti-Infective Agents, Urin

2001