Page last updated: 2024-10-25

ciprofloxacin and Adenomatous Polyposis Coli

ciprofloxacin has been researched along with Adenomatous Polyposis Coli in 3 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Adenomatous Polyposis Coli: A polyposis syndrome due to an autosomal dominant mutation of the APC genes (GENES, APC) on CHROMOSOME 5. The syndrome is characterized by the development of hundreds of ADENOMATOUS POLYPS in the COLON and RECTUM of affected individuals by early adulthood.

Research Excerpts

ExcerptRelevanceReference
"Pouchitis is the most frequent long-term complication of IPAA in patients with UC, with a cumulative prevalence of up to 50%."2.46Diagnosis and management of pouchitis and ileoanal pouch dysfunction. ( Navaneethan, U; Shen, B, 2010)
"The medical treatment of acute pouchitis was usually oral metronidazole (250 mg twice daily) for 2 weeks or oral ciprofloxacin (200 mg thrice daily) in patients who could not tolerate metronidazole."1.32Incidence and therapeutic outcome of pouchitis for ulcerative colitis in Japanese patients. ( Ikeuchi, H; Nakamura, M; Nakano, H; Noda, M; Uchino, M; Yamamura, T; Yanagi, H, 2004)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Navaneethan, U1
Shen, B1
Ikeuchi, H1
Nakano, H1
Uchino, M1
Nakamura, M1
Yanagi, H1
Noda, M1
Yamamura, T1
Hurst, RD1
Molinari, M1
Chung, TP1
Rubin, M1
Michelassi, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis[NCT00583531]Phase 22 participants (Actual)Interventional2007-03-31Terminated (stopped due to Lack of enrollment)
"A Phase 1b/2 Study to Demonstrate the Safety and Efficacy of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an Ileal Pouch-Anal Anastomosis (PROF). The PROF Study."[NCT05938465]Phase 1/Phase 250 participants (Anticipated)Interventional2023-10-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for ciprofloxacin and Adenomatous Polyposis Coli

ArticleYear
Diagnosis and management of pouchitis and ileoanal pouch dysfunction.
    Current gastroenterology reports, 2010, Volume: 12, Issue:6

    Topics: Adenomatous Polyposis Coli; Algorithms; Anti-Infective Agents; Antitrichomonal Agents; Ciprofloxacin

2010

Other Studies

2 other studies available for ciprofloxacin and Adenomatous Polyposis Coli

ArticleYear
Incidence and therapeutic outcome of pouchitis for ulcerative colitis in Japanese patients.
    Digestive surgery, 2004, Volume: 21, Issue:3

    Topics: Adenomatous Polyposis Coli; Adult; Anti-Infective Agents; Ciprofloxacin; Colitis, Ulcerative; Female

2004
Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:5

    Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Colitis,

1996
Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:5

    Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Colitis,

1996
Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:5

    Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Colitis,

1996
Prospective study of the incidence, timing and treatment of pouchitis in 104 consecutive patients after restorative proctocolectomy.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:5

    Topics: Adenomatous Polyposis Coli; Adolescent; Adult; Aged; Anti-Infective Agents; Ciprofloxacin; Colitis,

1996