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ciprofloxacin and Acute Lymphoid Leukemia

ciprofloxacin has been researched along with Acute Lymphoid Leukemia in 16 studies

Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.

Research Excerpts

ExcerptRelevanceReference
"Fluoroquinolones reduce occurrence of fever in adult cancer patients who develop neutropenia, but there has been no randomized controlled trial in children, and there are only a few studies considering resistance in intestinal floral after ciprofloxacin has been used."9.17Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy. ( Chelae, S; Khwanna, T; Laoprasopwattana, K; Sujjanunt, T; Suwankeeree, P; Tunyapanit, W, 2013)
"The purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis."8.31Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis ( Alıcı, N; Kaya, Z; Kırkız, S; Koçak, Ü, 2023)
"To report the first case of ciprofloxacin-associated hemolytic-uremic syndrome (HUS)."7.71Ciprofloxacin-associated hemolytic-uremic syndrome. ( Allan, DS; Barr, RM; Chin-Yee, IH; Clark, WF; Thompson, CM, 2002)
"Fluoroquinolones reduce occurrence of fever in adult cancer patients who develop neutropenia, but there has been no randomized controlled trial in children, and there are only a few studies considering resistance in intestinal floral after ciprofloxacin has been used."5.17Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy. ( Chelae, S; Khwanna, T; Laoprasopwattana, K; Sujjanunt, T; Suwankeeree, P; Tunyapanit, W, 2013)
"Compared to historical controls, patients in this study receiving prophylactic ciprofloxacin had a reduced rate and duration of hospitalization and incidence of Gram-negative bacteremia."5.11A pilot study of prophylactic ciprofloxacin during delayed intensification in children with acute lymphoblastic leukemia. ( Abbas, AA; Chedid, FD; Felimban, SK; Fryer, CJ; Khattab, TM; Yousef, AA, 2004)
"The purpose of this study was to identify risk factors and improve preventive strategies for febrile neutropenia (FEN) in children with leukemia who were receiving ciprofloxacin prophylaxis."4.31Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis ( Alıcı, N; Kaya, Z; Kırkız, S; Koçak, Ü, 2023)
"To report the first case of ciprofloxacin-associated hemolytic-uremic syndrome (HUS)."3.71Ciprofloxacin-associated hemolytic-uremic syndrome. ( Allan, DS; Barr, RM; Chin-Yee, IH; Clark, WF; Thompson, CM, 2002)
"Ciprofloxacin AUC24 was 16."1.56Population Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Prophylaxis in Pediatric Acute Lymphoblastic Leukemia Patients. ( Bierings, MB; de Haas, V; Kaspers, GJL; Mathôt, RAA; Pieters, R; Sassen, SDT; Te Loo, DMWW; Tissing, WJE; van den Bos, C; van der Sluis, IM; van Westreenen, M; Zwaan, CM, 2020)
"Ciprofloxacin therapy was initiated and renal function was restored within 2 days."1.33Pseudomonas aeruginosa infection: an uncommon cause of post-renal obstruction following induction therapy for acute lymphoblastic leukemia. ( Burghardt, KM; Feber, J; Filler, G; Halton, J; Leonard, M, 2006)
"In ciprofloxacin-treated patients the flora were almost completely ciprofloxacin-resistant, whereas in the control groups resistant flora were detected only occasionally."1.28Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin. ( Huovinen, P; Kotilainen, P; Nikoskelainen, J, 1990)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's6 (37.50)18.2507
2000's3 (18.75)29.6817
2010's4 (25.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Kaya, Z1
Alıcı, N1
Kırkız, S1
Koçak, Ü1
Sassen, SDT1
Mathôt, RAA1
Pieters, R1
de Haas, V1
Kaspers, GJL1
van den Bos, C1
Tissing, WJE1
Te Loo, DMWW1
Bierings, MB1
van Westreenen, M1
van der Sluis, IM1
Zwaan, CM1
Castagnola, E1
Moroni, C1
Bandettini, R1
Caprino, D1
Haupt, R1
Fatima, A1
Afridi, FI1
Qureshi, A1
Farooqi, BJ1
Hussain, A1
Yeh, TC1
Liu, HC1
Hou, JY1
Chen, KH1
Huang, TH1
Chang, CY1
Liang, DC1
Laoprasopwattana, K1
Khwanna, T1
Suwankeeree, P1
Sujjanunt, T1
Tunyapanit, W1
Chelae, S1
Yousef, AA1
Fryer, CJ1
Chedid, FD1
Abbas, AA1
Felimban, SK1
Khattab, TM1
Burghardt, KM1
Leonard, M1
Feber, J1
Halton, J1
Filler, G1
Rosolen, A1
Drigo, P1
Zanesco, L1
Horowitz, HW1
Holmgren, D1
Seiter, K1
Carlens, S1
Ringdén, O1
Aschan, J1
Hägglund, H1
Ljungman, P1
Mattsson, J1
Remberger, M1
Allan, DS1
Thompson, CM1
Barr, RM1
Clark, WF1
Chin-Yee, IH1
Donnelly, JP2
Maschmeyer, G1
Daenen, S1
Arning, M1
Wolf, HH1
Aul, C1
Heyll, A1
Scharf, RE1
Scheider, W1
Kotilainen, P1
Nikoskelainen, J1
Huovinen, P1
Weers-Pothoff, G1
Novakova, IR1
Muytjens, HL1

Trials

5 trials available for ciprofloxacin and Acute Lymphoid Leukemia

ArticleYear
Ciprofloxacin reduces occurrence of fever in children with acute leukemia who develop neutropenia during chemotherapy.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:3

    Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agen

2013
A pilot study of prophylactic ciprofloxacin during delayed intensification in children with acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2004, Volume: 43, Issue:6

    Topics: Adolescent; Anti-Infective Agents; Antibiotic Prophylaxis; Bacteremia; Child; Child, Preschool; Cipr

2004
Stepdown single agent antibiotic therapy for the management of the high risk neutropenic adult with hematologic malignancies.
    Leukemia & lymphoma, 1996, Volume: 23, Issue:1-2

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Ciproflo

1996
Selective oral antimicrobial prophylaxis for the prevention of infection in acute leukaemia-ciprofloxacin versus co-trimoxazole plus colistin. The EORTC-Gnotobiotic Project Group.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:4-5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Ciprofloxacin; Colistin; Drug Therap

1992
Infection prophylaxis in neutropenic patients with acute leukaemia--a randomized, comparative study with ofloxacin, ciprofloxacin and co-trimoxazole/colistin.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 26 Suppl D

    Topics: Bacterial Infections; Ciprofloxacin; Colistin; Humans; Neutropenia; Ofloxacin; Precursor Cell Lympho

1990

Other Studies

11 other studies available for ciprofloxacin and Acute Lymphoid Leukemia

ArticleYear
Identifying Risk Factors and Improving Preventive Strategies for Febrile Neutropenia in Children with Leukemia Receiving Ciprofloxacin Prophylaxis
    Turkish journal of haematology : official journal of Turkish Society of Haematology, 2023, 08-31, Volume: 40, Issue:3

    Topics: Child; Ciprofloxacin; Febrile Neutropenia; Humans; Leukemia, Myeloid, Acute; Precursor Cell Lymphobl

2023
Population Pharmacokinetics and Pharmacodynamics of Ciprofloxacin Prophylaxis in Pediatric Acute Lymphoblastic Leukemia Patients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 11-05, Volume: 71, Issue:8

    Topics: Anti-Bacterial Agents; Area Under Curve; Child; Ciprofloxacin; Drug Resistance, Bacterial; Humans; M

2020
Ciprofloxacin prophylaxis in children with acute leukemia in an era of increasing antibiotic resistance.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:5

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Ciprofloxacin; Female; Fever; Humans; Male; Neutropeni

2013
Bacteremia due to Aeromonas hydrophila in acute lymphoblastic leukemia.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:12

    Topics: Acute Disease; Aeromonas hydrophila; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Female; Fever

2013
Severe infections in children with acute leukemia undergoing intensive chemotherapy can successfully be prevented by ciprofloxacin, voriconazole, or micafungin prophylaxis.
    Cancer, 2014, Apr-15, Volume: 120, Issue:8

    Topics: Adolescent; Antibiotic Prophylaxis; Antifungal Agents; Antineoplastic Agents; Child; Child, Preschoo

2014
Pseudomonas aeruginosa infection: an uncommon cause of post-renal obstruction following induction therapy for acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2006, Volume: 46, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Anuria; Ciprofloxacin; Humans; Hypertension; Infant;

2006
Acute hemiparesis associated with ciprofloxacin.
    BMJ (Clinical research ed.), 1994, Nov-26, Volume: 309, Issue:6966

    Topics: Acute Disease; Adolescent; Ciprofloxacin; Cranial Nerve Diseases; Female; Hemiplegia; Humans; Precur

1994
Risk factors in bone marrow transplant recipients with leukaemia. Increased relapse risk in patients treated with ciprofloxacin for gut decontamination.
    Clinical transplantation, 1998, Volume: 12, Issue:2

    Topics: Adult; Anti-Infective Agents; Bone Marrow Transplantation; Ciprofloxacin; Cyclophosphamide; Disease-

1998
Ciprofloxacin-associated hemolytic-uremic syndrome.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:6

    Topics: Anti-Infective Agents; Ciprofloxacin; Hemolytic-Uremic Syndrome; Humans; Male; Middle Aged; Precurso

2002
Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin.
    The Journal of infectious diseases, 1990, Volume: 161, Issue:1

    Topics: Aged; Ciprofloxacin; Coagulase; Drug Resistance, Microbial; Female; Humans; Immune Tolerance; Leukem

1990
Bacteraemia caused by Stomatococcus mucilaginosus in a granulocytopenic patient with acute lymphocytic leukaemia.
    The Netherlands journal of medicine, 1989, Volume: 35, Issue:3-4

    Topics: Adult; Agranulocytosis; Amsacrine; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Proto

1989