ciprofloxacin has been researched along with Abnormalities, Autosome in 14 studies
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.
ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.
| Excerpt | Relevance | Reference |
|---|---|---|
| "OFX did not induce any significant chromosomal aberrations in human lymphocytes." | 1.36 | A comparative analysis of chromosomal aberrations in cultured human lymphocytes due to fluoroquinolone drugs at different expression periods. ( Anupama, M; Murthy, PB; Seiler, JP, 2010) |
| "Ciprofloxacin is a bactericidal drug which is being used widely throughout the world for the treatment of various bacterial infection." | 1.35 | Genotoxic and cytotoxic effects of antibacterial drug, ciprofloxacin, on human lymphocytes in vitro. ( Ambulkar, PS; Ghosh, SK; Ingole, IV; Pal, AK, 2009) |
| " Therefore, ciprofloxacin is considered to be safe for therapeutic use." | 1.31 | Ciprofloxacin: in vivo genotoxicity studies. ( Ahr, HJ; Brendler-Schwaab, SY; Herbold, BA, 2001) |
| "Chromosomal aberrations were evaluated in cultures of human peripheral lymphocytes from eight healthy donors, exposed to the antimicrobial enrofloxacin (EFX) or to its major metabolite ciprofloxacin (CFX)." | 1.30 | Chromosomal aberrations in human lymphocytes exposed in vitro to enrofloxacin and ciprofloxacin. ( García Ovando, H; Gorla, N; Larripa, I, 1999) |
| "Ciprofloxacin was postulated to be specific for the target DNA gyrase, the prokaryotic homologue of DNA topoisomerase type II enzyme." | 1.29 | Ciprofloxacin: mammalian DNA topoisomerase type II poison in vivo. ( Agarwal, K; Mukherjee, A; Sen, S, 1993) |
| "The frequency of chromosomal aberrations, mainly dicentrics, due to telomeric associations, increased after 95-168 days of cultivation of contaminated cells." | 1.29 | [The effect of mycoplasmal contamination of cultures of skin fibroblasts from the Indian muntjac and of the subsequent decontamination of the cultures using ciprofloxacin on the karyotypic structure of the cell line]. ( Efremova, TN; Polianskaia, GG, 1994) |
| "The degree of increase of chromosomal aberrations in the subline of Indian muntjak skin fibroblasts was in average 1." | 1.29 | [The genotoxic effect of ciprofloxacin on cultured cells from the kangaroo rat kidney and on skin fibroblasts from the Indian muntjac]. ( Polianskaia, GG; Sizova, LS, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anupama, M | 1 |
| Seiler, JP | 1 |
| Murthy, PB | 1 |
| Ambulkar, PS | 1 |
| Ghosh, SK | 1 |
| Ingole, IV | 1 |
| Pal, AK | 1 |
| Mukherjee, A | 1 |
| Sen, S | 1 |
| Agarwal, K | 1 |
| Polianskaia, GG | 5 |
| Sizova, LS | 2 |
| Efremova, TN | 3 |
| Fridlianskaia, II | 1 |
| Curry, PT | 1 |
| Kropko, ML | 1 |
| Garvin, JR | 1 |
| Fiedler, RD | 1 |
| Theiss, JC | 1 |
| Chételat, AA | 1 |
| Albertini, S | 1 |
| Gocke, E | 1 |
| Kinev, AV | 1 |
| Sakuta, GA | 1 |
| Aseeva, EV | 1 |
| Hartmann, A | 1 |
| Golet, EM | 1 |
| Gartiser, S | 1 |
| Alder, AC | 1 |
| Koller, T | 1 |
| Widmer, RM | 1 |
| Gorla, N | 1 |
| García Ovando, H | 1 |
| Larripa, I | 1 |
| Herbold, BA | 1 |
| Brendler-Schwaab, SY | 1 |
| Ahr, HJ | 1 |
| Mitelman, F | 1 |
| Kolnig, AM | 1 |
| Strömbeck, B | 1 |
| Norrby, R | 1 |
| Kromann-Andersen, B | 1 |
| Sommer, P | 1 |
| Wadstein, J | 1 |
1 trial available for ciprofloxacin and Abnormalities, Autosome
| Article | Year |
|---|---|
No cytogenetic effects of quinolone treatment in humans.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Chromosome Aberrations; Ciprofloxacin; Female | 1988 |
13 other studies available for ciprofloxacin and Abnormalities, Autosome
| Article | Year |
|---|---|
A comparative analysis of chromosomal aberrations in cultured human lymphocytes due to fluoroquinolone drugs at different expression periods.
Topics: Anti-Infective Agents; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; DNA Repli | 2010 |
Genotoxic and cytotoxic effects of antibacterial drug, ciprofloxacin, on human lymphocytes in vitro.
Topics: Adult; Anti-Infective Agents; Chromosome Aberrations; Ciprofloxacin; Humans; In Vitro Techniques; Ly | 2009 |
Ciprofloxacin: mammalian DNA topoisomerase type II poison in vivo.
Topics: Analysis of Variance; Animals; Bone Marrow Cells; Chromosome Aberrations; Ciprofloxacin; DNA Damage; | 1993 |
[A cytogenetic study of the Chinese hamster lung cell line V-79 infected with Mycoplasma arginini and decontaminated using ciprofloxacin].
Topics: Animals; Cell Line; Chromosome Aberrations; Ciprofloxacin; Cricetinae; Cricetulus; Drug Evaluation, | 1994 |
[The effect of mycoplasmal contamination of cultures of skin fibroblasts from the Indian muntjac and of the subsequent decontamination of the cultures using ciprofloxacin on the karyotypic structure of the cell line].
Topics: Acholeplasma laidlawii; Animals; Cell Line; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; | 1994 |
[The effect of Mycoplasma contamination and decontamination with ciprofloxacin on the karyotypic structure of the Chinese hamster V-79 lung cell line].
Topics: Acholeplasma laidlawii; Animals; Cell Line; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; | 1993 |
In vitro induction of micronuclei and chromosome aberrations by quinolones: possible mechanisms.
Topics: Animals; Anti-Infective Agents; Cell Cycle; Cell Survival; Cells, Cultured; Chromosome Aberrations; | 1996 |
The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA breakage (Comet assay).
Topics: Animals; Anti-Infective Agents; Carcinogens; Chromosome Aberrations; Ciprofloxacin; Cricetinae; DNA | 1996 |
[The genotoxic effect of ciprofloxacin on cultured cells from the kangaroo rat kidney and on skin fibroblasts from the Indian muntjac].
Topics: Animals; Anti-Infective Agents; Cell Line; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; D | 1996 |
[Effect of an extracellular heat shock protein on chromosome variability in Indian muntjak cultured skin fibroblasts].
Topics: Animals; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; Extracellular Space; Fibroblasts; H | 1997 |
Primary DNA damage but not mutagenicity correlates with ciprofloxacin concentrations in German hospital wastewaters.
Topics: Animals; Anti-Infective Agents; Chromosome Aberrations; Ciprofloxacin; Cricetinae; DNA Damage; Germa | 1999 |
Chromosomal aberrations in human lymphocytes exposed in vitro to enrofloxacin and ciprofloxacin.
Topics: Adult; Anti-Infective Agents; Cells, Cultured; Chromosome Aberrations; Ciprofloxacin; Enrofloxacin; | 1999 |
Ciprofloxacin: in vivo genotoxicity studies.
Topics: 2-Acetylaminofluorene; Animals; Area Under Curve; Bone Marrow Cells; Chromosome Aberrations; Ciprofl | 2001 |