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ciprofibrate and Arteriosclerosis

ciprofibrate has been researched along with Arteriosclerosis in 10 studies

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
"Ciprofibrate is an effective hypolipidemic agent, also lowering the level of fibrinogen."5.30[The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. ( Cibulova, L; Fedelesova, V; Gajdos, M; Huttova, D; Krivosikova, Z; Mongiellova, V; Polak, F, 1999)
"Ciprofibrate did not inhibit thromboxane B 2 synthesis in platelets."2.70Ciprofibrate increases plasma concentration of platelet-derived growth factor AB in patients with advanced atherosclerosis and hyperlipidemia independently of its hypolipidemic effects. ( Cibulová, L; Dzúrik, R; Gajdos, M; Huttová, D; Krivosíková, Z; Mongiellová, V; Spustová, V, 2001)
"Ciprofibrate has a potent hypolipidemic effect, especially a decrease in triglycerides, VLDL and fibrinogen, and an increase in HDL-cholesterol, but does not influence glycemic control nor insulin action."2.69Ciprofibrate effects on carbohydrate and lipid metabolism in type 2 diabetes mellitus subjects. ( Ascaso, JF; Carmena, R; Hernández-Mijares, A; Lluch, I; Martínez-Triguero, ML; Vizcarra, E, 2000)
"Dyslipidaemia in patients with type 2 diabetes commonly consists of elevated triglyceride levels; normal or slightly elevated low-density lipoprotein (LDL)-cholesterol levels with a preponderance of small, dense LDL particles; and low high-density lipoprotein (HDL)-cholesterol levels with a preponderance of small, dense HDL."2.42LDL-cholesterol, HDL-cholesterol or triglycerides--which is the culprit? ( Taskinen, MR, 2003)
"Ciprofibrate is a hypolipidaemic compound that acts primarily by enhancing the oxidation of fatty acids in the liver and, consequently, decreasing the production of hepatic VLDL."1.32The peroxisome-proliferator-activated receptor alpha agonist ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E. ( Borensztajn, J; Fu, T; Kashireddy, P, 2003)
"Ciprofibrate is an effective hypolipidemic agent, also lowering the level of fibrinogen."1.30[The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia]. ( Cibulova, L; Fedelesova, V; Gajdos, M; Huttova, D; Krivosikova, Z; Mongiellova, V; Polak, F, 1999)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's7 (70.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fu, T2
Kashireddy, P1
Borensztajn, J2
Taskinen, MR1
Guerin, M1
Le Goff, W1
Frisdal, E1
Schneider, S1
Milosavljevic, D1
Bruckert, E1
Chapman, MJ1
Mukhopadhyay, D1
Davidson, NO1
Irizar, A1
Ioannides, C1
Schonfeld, G1
Gajdos, M2
Fedelesova, V1
Mongiellova, V2
Cibulova, L2
Huttova, D2
Polak, F1
Krivosikova, Z2
Hernández-Mijares, A1
Lluch, I1
Vizcarra, E1
Martínez-Triguero, ML1
Ascaso, JF1
Carmena, R1
Dobiásová, M1
Frohlich, J1
Spustová, V1
Dzúrik, R1

Reviews

2 reviews available for ciprofibrate and Arteriosclerosis

ArticleYear
LDL-cholesterol, HDL-cholesterol or triglycerides--which is the culprit?
    Diabetes research and clinical practice, 2003, Volume: 61 Suppl 1

    Topics: Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Controlled Clinical Trials as

2003
The effects of fibrates on lipoprotein and hemostatic coronary risk factors.
    Atherosclerosis, 1994, Volume: 111, Issue:2

    Topics: Arteriosclerosis; Bezafibrate; Blood Coagulation; Clofibric Acid; Coronary Disease; Fenofibrate; Fib

1994

Trials

3 trials available for ciprofibrate and Arteriosclerosis

ArticleYear
Action of ciprofibrate in type IIb hyperlipoproteinemia: modulation of the atherogenic lipoprotein phenotype and stimulation of high-density lipoprotein-mediated cellular cholesterol efflux.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:8

    Topics: Adult; Animals; Apolipoprotein A-I; Apolipoproteins B; Arteriosclerosis; Cholesterol; Cholesterol Es

2003
Ciprofibrate effects on carbohydrate and lipid metabolism in type 2 diabetes mellitus subjects.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2000, Volume: 10, Issue:1

    Topics: Adult; Aged; Apolipoproteins B; Area Under Curve; Arteriosclerosis; Blood Glucose; Carbohydrate Meta

2000
Ciprofibrate increases plasma concentration of platelet-derived growth factor AB in patients with advanced atherosclerosis and hyperlipidemia independently of its hypolipidemic effects.
    Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:5

    Topics: Aged; Arteriosclerosis; Aspirin; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Fi

2001

Other Studies

5 other studies available for ciprofibrate and Arteriosclerosis

ArticleYear
The peroxisome-proliferator-activated receptor alpha agonist ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E.
    The Biochemical journal, 2003, Aug-01, Volume: 373, Issue:Pt 3

    Topics: Animals; Apolipoproteins; Arteriosclerosis; Blotting, Northern; Blotting, Western; Clofibric Acid; F

2003
The peroxisome proliferator-activated receptor alpha (PPARalpha) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice: effects on plasma lipoproteins and the development of atherosclerotic lesions.
    The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27

    Topics: Animals; Aorta; Apolipoproteins B; Arteriosclerosis; Blotting, Western; Cholesterol; Clofibric Acid;

2004
Expression and inducibility of cytochrome P450 proteins belonging to families 2,3 and 4 in the rabbit aorta.
    Biochemical and biophysical research communications, 1995, Aug-24, Volume: 213, Issue:3

    Topics: Animals; Aorta; Arteriosclerosis; Clofibric Acid; Cytochrome P-450 Enzyme System; Enzyme Induction;

1995
[The effect of monotherapy with ciprofibrate and in combination with acetylsalicylic acid on the spectrum of lipids, thromboxane and fibrinogen in patients with atherosclerosis and hyperlipoproteinemia].
    Bratislavske lekarske listy, 1999, Volume: 100, Issue:8

    Topics: Aged; Arteriosclerosis; Aspirin; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Fi

1999
[The new atherogenic plasma index reflects the triglyceride and HDL-cholesterol ratio, the lipoprotein particle size and the cholesterol esterification rate: changes during lipanor therapy].
    Vnitrni lekarstvi, 2000, Volume: 46, Issue:3

    Topics: Adult; Aged; Arteriosclerosis; Child; Cholesterol; Cholesterol, HDL; Clofibric Acid; Esterification;

2000