cinoxacin has been researched along with Urinary Tract Infections in 40 studies
Cinoxacin: Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
cinoxacin : A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.
Urinary Tract Infections: Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective, randomized, double-blind trial, ciprofloxacin (250 mg orally, twice daily) was compared with cinoxacin (500 mg orally, twice daily) in 60 patients with urinary tract infections." | 9.06 | Ciprofloxacin versus cinoxacin in therapy of urinary tract infections. A randomized, double-blind trial. ( Alpert, ML; Citron, DM; Ginsberg, BP; Goldstein, EJ; Greenway, FL; Kahn, RM, 1987) |
| "This paper describes an open assessment of cinoxacin in the treatment of 30 outpatients with symptomatic urinary tract infections caused by Escherichia coli, Klebsiella, Proteus mirabilis, and Enterobacter." | 9.05 | Treatment of outpatient urinary tract infections with cinoxacin. ( Jones, GW; Mulholland, SG, 1980) |
| "We gave cinoxacin to 125 patients with initial and recurrent urinary tract infections to investigate the safety and efficacy of this new antimicrobial agent." | 9.05 | Cinoxacin therapy for urinary tract infections: therapeutic safety and efficacy. ( Cox, CE; Simmons, JR, 1982) |
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 9.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "In the TMP group one recurrence and in the CNO group two recurrences occurred during treatment, two recurrences being observed in each group during the follow-up period of 4-6 weeks." | 6.66 | Cinoxacin vs trimethoprim--safety and efficacy in the prophylaxis of uncomplicated urinary tract infections. ( Seppänen, J, 1988) |
| "Norfloxacin is a valuable addition to the oral antimicrobial agents available for the treatment of urinary tract infection." | 6.65 | Comparative study using norfloxacin and amoxycillin in the treatment of complicated urinary tract infections in geriatric patients. ( Leigh, DA; Marriner, J; Smith, EC, 1984) |
| "TWo dosage regimens of cinoxacin, 250 mg." | 6.65 | Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens. ( Cox, CE; Simmons, JR, 1981) |
| "Cinoxacin was as effective as trimethoprim-sulfamethoxazole without the emergence of resistant bacteria associated with trimethoprim-sulfamethoxazole." | 6.65 | Comparison of cinoxacin and trimethoprim-sulfamethoxazole in the treatment of urinary tract infections. ( Flynn, S; Jones, J; Schaeffer, AJ, 1981) |
| "Cinoxacin is a urinary antibacterial drug closely related structurally to nalidixic acid." | 6.36 | Cinoxacin. A review of its pharmacological properties and therapeutic efficacy in the treatment of urinary tract infections. ( Heel, RC; Romankiewicz, JA; Sisca, TS, 1983) |
| "Cinoxacin is an oral synthetic antibacterial agent, of the second generation quinolones group, with excellent efficacy in respiratory, intra-abdominal, pelvic, and skin and soft tissue infections." | 5.32 | Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction. ( Emiliani, F; Quercia, O; Rafanelli, S; Stefanini, GF, 2003) |
| "Cinoxacin was administered to 30 outpatients with chronic complicated urinary tract infection for 57." | 5.27 | [Clinical study on long-term cinoxacin therapy for outpatients with chronic complicated urinary tract infections]. ( Katoh, M; Matsumoto, J; Tada, S; Yamasaki, Y, 1985) |
| "Cinoxacin was found to have a half-life of 2." | 5.26 | Cinoxacin in urinary tract infections. Theoretical and practical considerations. ( Frimodt-Møller, N; Madsen, PO; Maigaard, S; Nielsen, OS; Rodriguez, N; Welling, PG, 1981) |
| "A randomized clinical study was conducted in order to compare the effectiveness of norfloxacin and cinoxacin in complicated urinary tract infections." | 5.06 | [Comparative evaluation of norfloxacin and cinoxacin in the therapy of complicated infections of the urinary tract]. ( Cristiano, P; Della Vittoria Scarpati, M; Iovene, MR; Manguso, L; Morelli, G; Simioli, F, 1989) |
| "In a prospective, randomized, double-blind trial, ciprofloxacin (250 mg orally, twice daily) was compared with cinoxacin (500 mg orally, twice daily) in 60 patients with urinary tract infections." | 5.06 | Ciprofloxacin versus cinoxacin in therapy of urinary tract infections. A randomized, double-blind trial. ( Alpert, ML; Citron, DM; Ginsberg, BP; Goldstein, EJ; Greenway, FL; Kahn, RM, 1987) |
| "A single-blind comparison was undertaken to evaluate 250 mg of cinoxacin and 100 mg of nitrofurantoin, both drugs being given four times a day, for the treatment of urinary tract infections." | 5.05 | Single-blind comparison of cinoxacin and nitrofurantoin in the treatment of urinary tract infection. ( Schneider, RE, 1982) |
| "We gave cinoxacin to 125 patients with initial and recurrent urinary tract infections to investigate the safety and efficacy of this new antimicrobial agent." | 5.05 | Cinoxacin therapy for urinary tract infections: therapeutic safety and efficacy. ( Cox, CE; Simmons, JR, 1982) |
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 5.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "Twenty-two patients with chronic complicated urinary tract infections were treated with 400 to 1,200 mg/day cinoxacin for 2 to 12 months." | 3.67 | [Long-term cinoxacin therapy for chronic complicated urinary tract infection]. ( Ueyama, H, 1984) |
| "The present study was carried out with the aim of comparing the microbiological and clinical efficacy of norfloxacin, cinoxacin and aztreonam in urinary tract infections." | 3.67 | Treatment of urinary infections: clinical perspectives. ( Carlone, NA; Fontana, G; Laudi, M; Savoia, D, 1987) |
| "The urinary antibacterial drugs cinoxacin (Cinobac) and nitrofurantoin (Macrodantin) were compared for efficacy and side effects in the treatment of uncomplicated lower urinary tract infections occurring in elderly patients admitted to a rehabilitation hospital." | 3.66 | A comparative drug study of lower urinary tract infections in elderly patients. ( Lindan, R, 1981) |
| "In the TMP group one recurrence and in the CNO group two recurrences occurred during treatment, two recurrences being observed in each group during the follow-up period of 4-6 weeks." | 2.66 | Cinoxacin vs trimethoprim--safety and efficacy in the prophylaxis of uncomplicated urinary tract infections. ( Seppänen, J, 1988) |
| "Norfloxacin is a valuable addition to the oral antimicrobial agents available for the treatment of urinary tract infection." | 2.65 | Comparative study using norfloxacin and amoxycillin in the treatment of complicated urinary tract infections in geriatric patients. ( Leigh, DA; Marriner, J; Smith, EC, 1984) |
| "cinoxacin were compared to 1 g." | 2.65 | A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection. ( Bucy, JG, 1981) |
| "TWo dosage regimens of cinoxacin, 250 mg." | 2.65 | Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens. ( Cox, CE; Simmons, JR, 1981) |
| "Cinoxacin was as effective as trimethoprim-sulfamethoxazole without the emergence of resistant bacteria associated with trimethoprim-sulfamethoxazole." | 2.65 | Comparison of cinoxacin and trimethoprim-sulfamethoxazole in the treatment of urinary tract infections. ( Flynn, S; Jones, J; Schaeffer, AJ, 1981) |
| "Cinoxacin is an oral synthetic antibacterial agent, of the second generation quinolones group, with excellent efficacy in respiratory, intra-abdominal, pelvic, and skin and soft tissue infections." | 1.32 | Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction. ( Emiliani, F; Quercia, O; Rafanelli, S; Stefanini, GF, 2003) |
| "Cinoxacin was administered to 30 outpatients with chronic complicated urinary tract infection for 57." | 1.27 | [Clinical study on long-term cinoxacin therapy for outpatients with chronic complicated urinary tract infections]. ( Katoh, M; Matsumoto, J; Tada, S; Yamasaki, Y, 1985) |
| "Ninety-seven patients with a history of recurrent bacteriuria were treated with cinoxacin in a dosage of either 250 mg (48 patients) or 500 mg (49 patients) 12-hourly for seven days." | 1.27 | Successful use of reduced dosage of cinoxacin in the treatment of recurrent urinary infection. ( Bax, R; Brumfitt, W; Hamilton-Miller, JM; Smith, GW, 1985) |
| "Cinoxacin was found to have a half-life of 2." | 1.26 | Cinoxacin in urinary tract infections. Theoretical and practical considerations. ( Frimodt-Møller, N; Madsen, PO; Maigaard, S; Nielsen, OS; Rodriguez, N; Welling, PG, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (97.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quercia, O | 1 |
| Rafanelli, S | 1 |
| Emiliani, F | 1 |
| Stefanini, GF | 1 |
| Leigh, DA | 1 |
| Smith, EC | 1 |
| Marriner, J | 1 |
| Sisca, TS | 1 |
| Heel, RC | 1 |
| Romankiewicz, JA | 1 |
| Ueyama, H | 1 |
| Scheckler, WE | 1 |
| Burt, RA | 1 |
| Paulson, DF | 1 |
| Van Vliet, P | 1 |
| Denis, L | 1 |
| Jones, GW | 1 |
| Mulholland, SG | 1 |
| Chantrie, M | 1 |
| Hardy, JC | 1 |
| Landes, RR | 2 |
| Bucy, JG | 1 |
| Cox, CE | 2 |
| Simmons, JR | 2 |
| Schneider, RE | 1 |
| de Jersey, P | 1 |
| Wooller, HO | 1 |
| Bouffioux, C | 1 |
| Godechard, P | 1 |
| Renard, A | 1 |
| Penders, L | 1 |
| Schaeffer, AJ | 2 |
| Jones, JM | 1 |
| Flynn, SS | 1 |
| Briedigkeit, H | 1 |
| Schimmelpfennig, R | 1 |
| Buder, R | 1 |
| Precht, K | 1 |
| Dröseler, H | 1 |
| Finkelstein, LH | 1 |
| Arsht, DB | 1 |
| Manfrey, SJ | 1 |
| Stamey, TA | 1 |
| Madsen, PO | 1 |
| Frimodt-Møller, N | 1 |
| Maigaard, S | 1 |
| Nielsen, OS | 1 |
| Rodriguez, N | 1 |
| Welling, PG | 1 |
| Drylie, DM | 1 |
| Lindan, R | 1 |
| Flynn, S | 1 |
| Jones, J | 1 |
| Barnham, M | 1 |
| Gaya, H | 1 |
| Cristiano, P | 1 |
| Morelli, G | 1 |
| Simioli, F | 1 |
| Iovene, MR | 1 |
| Della Vittoria Scarpati, M | 1 |
| Manguso, L | 1 |
| Bardi, M | 1 |
| Manzoni, A | 1 |
| Seppänen, J | 1 |
| Pfau, A | 1 |
| Sacks, TG | 1 |
| Shapiro, M | 1 |
| Montefiore, F | 1 |
| Bassi, G | 1 |
| Laguzzi, E | 1 |
| Mele, L | 1 |
| Nihira, H | 1 |
| Nakano, H | 1 |
| Fontana, G | 1 |
| Laudi, M | 1 |
| Carlone, NA | 1 |
| Savoia, D | 1 |
| Goldstein, EJ | 1 |
| Kahn, RM | 1 |
| Alpert, ML | 1 |
| Ginsberg, BP | 1 |
| Greenway, FL | 1 |
| Citron, DM | 1 |
| Hayashi, Y | 1 |
| Terao, E | 1 |
| Yamasaki, I | 1 |
| Pelta, DE | 1 |
| Bowring, AR | 1 |
| Matsumoto, J | 1 |
| Yamasaki, Y | 1 |
| Katoh, M | 1 |
| Tada, S | 1 |
| Brumfitt, W | 1 |
| Smith, GW | 1 |
| Hamilton-Miller, JM | 1 |
| Bax, R | 1 |
2 reviews available for cinoxacin and Urinary Tract Infections
| Article | Year |
|---|---|
Cinoxacin. A review of its pharmacological properties and therapeutic efficacy in the treatment of urinary tract infections.
Topics: Animals; Bacteria; Cinoxacin; Drug Resistance, Microbial; Humans; Kinetics; Pyridazines; Urinary Tra | 1983 |
[Prevention of recurrence of repetitious urinary tract infections in women].
Topics: Cinoxacin; Female; Humans; Pyridazines; Recurrence; Sex Factors; Urinary Tract Infections | 1986 |
20 trials available for cinoxacin and Urinary Tract Infections
| Article | Year |
|---|---|
Comparative study using norfloxacin and amoxycillin in the treatment of complicated urinary tract infections in geriatric patients.
Topics: Aged; Amoxicillin; Anti-Infective Agents, Urinary; Cinoxacin; Enterobacteriaceae; Humans; Microbial | 1984 |
Comparison of low-dose cinoxacin therapy and placebo in the prevention of recurrent urinary tract infections.
Topics: Adult; Aged; Cinoxacin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Middle Aged; | 1982 |
Cinoxacin (Cinobac) for urinary tract infections.
Topics: Bacteria; Bacterial Infections; Cinoxacin; Clinical Trials as Topic; Humans; Pyridazines; Urinary Tr | 1980 |
Treatment of outpatient urinary tract infections with cinoxacin.
Topics: Adolescent; Adult; Aged; Cinoxacin; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; | 1980 |
[Prevention of recurrent urinary tract infection with cinoxacin. A comparative study with nitrofurantoin].
Topics: Adult; Aged; Cinoxacin; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Nitrofurantoin; | 1980 |
Cinoxacin for treatment and prevention of recurrent urinary tract infection.
Topics: Amoxicillin; Bacteria; Bacterial Infections; Cinoxacin; Clinical Trials as Topic; Double-Blind Metho | 1981 |
A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection.
Topics: Adult; Central Nervous System Diseases; Cinoxacin; Clinical Trials as Topic; Escherichia coli Infect | 1981 |
Cinoxacin (Cinobac)--a new drug for urinary tract infections.
Topics: Cinoxacin; Clinical Trials as Topic; Humans; Pyridazines; Urinary Tract Infections | 1981 |
Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens.
Topics: Cinoxacin; Clinical Trials as Topic; Drug Administration Schedule; Enterobacteriaceae Infections; Es | 1981 |
Single-blind comparison of cinoxacin and nitrofurantoin in the treatment of urinary tract infection.
Topics: Adult; Age Factors; Aged; Cinoxacin; Drug Evaluation; Escherichia coli Infections; Female; Humans; M | 1982 |
Cinoxacin therapy for urinary tract infections: therapeutic safety and efficacy.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Cinoxacin; Clinical Trials as Topic; Female | 1982 |
Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Cinoxacin; Clinical Trials as | 1982 |
[Comparative study of cinoxacin (Cinobac), nitrofurantoin (Furadantine MC) and oxolinic acid (Uritrate) in urinary tract infections. Results of a random study of three groups of 30 patients with uncomplicated urinary infections].
Topics: Adolescent; Adult; Aged; Cinoxacin; Female; Humans; Male; Middle Aged; Nitrofurantoin; Oxolinic Acid | 1982 |
[A comparison of cinoxacin and nalidixic acid in the treatment of chronic urinary tract infections].
Topics: Bacteriuria; Chronic Disease; Cinoxacin; Cystitis; Gastrointestinal Diseases; Humans; Nalidixic Acid | 1982 |
Cinoxacin and nalidixic acid in treatment of urinary tract infections.
Topics: Bacterial Infections; Cinoxacin; Humans; Microbial Sensitivity Tests; Nalidixic Acid; Pyridazines; U | 1981 |
Comparison of cinoxacin and trimethoprim-sulfamethoxazole in the treatment of urinary tract infections.
Topics: Adult; Cinoxacin; Drug Combinations; Drug Resistance; Enterobacteriaceae; Enterobacteriaceae Infecti | 1981 |
[Comparative evaluation of norfloxacin and cinoxacin in the therapy of complicated infections of the urinary tract].
Topics: Bacteria; Bacteriuria; Cinoxacin; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Male; Mi | 1989 |
Cinoxacin vs trimethoprim--safety and efficacy in the prophylaxis of uncomplicated urinary tract infections.
Topics: Adolescent; Adult; Cinoxacin; Double-Blind Method; Female; Humans; Middle Aged; Pyridazines; Random | 1988 |
Ciprofloxacin versus cinoxacin in therapy of urinary tract infections. A randomized, double-blind trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cinoxacin; Ciprofloxacin; Clinical | 1987 |
Management of the urethral syndrome in general practice.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Cinoxacin; Clinical Trials as Topic; Drug C | 1985 |
18 other studies available for cinoxacin and Urinary Tract Infections
| Article | Year |
|---|---|
Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction.
Topics: 4-Quinolones; Anaphylaxis; Anti-Infective Agents; Cinoxacin; Double-Blind Method; Humans; Inflammati | 2003 |
[Long-term cinoxacin therapy for chronic complicated urinary tract infection].
Topics: Aged; Chronic Disease; Cinoxacin; Female; Humans; Male; Middle Aged; Pyridazines; Time Factors; Urin | 1984 |
[Comparative study with cinoxacin, a new drug for the treatment of urinary tract infections].
Topics: Cinoxacin; Drug Combinations; Female; Humans; Male; Middle Aged; Pyridazines; Sulfamethoxazole; Trim | 1980 |
[Cinobar, a new antimicrobial agent for the treatment of urinary infections].
Topics: Adult; Cinoxacin; Escherichia coli Infections; Female; Humans; Male; Nalidixic Acid; Pyridazines; Ra | 1980 |
Prophylactic efficacy of cinoxacin in recurrent urinary tract infection: biologic effects on the vaginal and fecal flora.
Topics: Adult; Aged; Bacteriuria; Cinoxacin; Drug Evaluation; Feces; Female; Humans; Middle Aged; Pyridazine | 1982 |
Cinoxacin and trimethoprim with sulfamethoxazole in the treatment of infections of the urinary tract: a clinical comparison.
Topics: Adult; Aged; Bacterial Infections; Cinoxacin; Drug Combinations; Drug Evaluation; Female; Humans; Ma | 1982 |
Cinoxacin: an overview.
Topics: Bacteria; Cinoxacin; Drug Resistance, Microbial; Enterobacteriaceae Infections; Female; Humans; Male | 1981 |
Cinoxacin in urinary tract infections. Theoretical and practical considerations.
Topics: Animals; Bacterial Infections; Body Fluids; Cinoxacin; Dogs; Female; Humans; Kinetics; Male; Prostat | 1981 |
A comparative drug study of lower urinary tract infections in elderly patients.
Topics: Aged; Cinoxacin; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Microbial | 1981 |
Long-term low dose cinoxacin therapy for the prevention of recurrent urinary tract infections.
Topics: Adult; Cinoxacin; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Pilot Pro | 1980 |
In vitro susceptibility of urinary isolates of Escherichia coli to cinoxacin.
Topics: Cinoxacin; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Nalid | 1979 |
[Treatment of postoperative urinary infections in obstetrics and gynecology with cinoxacin].
Topics: Cesarean Section; Cinoxacin; Female; Genitalia, Female; Humans; Postoperative Complications; Pyridaz | 1988 |
Prevention of recurrent urinary tract infections in premenopausal women by post-coital administration of cinoxacin.
Topics: Adult; Cinoxacin; Coitus; Drug Administration Schedule; Escherichia coli Infections; Female; Humans; | 1988 |
[Cinoxacin in infections of the lower urinary tract].
Topics: Adult; Aged; Bacteria; Cinoxacin; Cystitis; Female; Humans; Male; Middle Aged; Pyridazines; Time Fac | 1988 |
Treatment of urinary infections: clinical perspectives.
Topics: Adult; Aztreonam; Cinoxacin; Drug Resistance, Microbial; Escherichia coli; Female; Humans; Klebsiell | 1987 |
[Study of clinical efficacy and safety of long-term cinoxacin therapy of chronic urogenital organ infection].
Topics: Adult; Aged; Chronic Disease; Cinoxacin; Drug Evaluation; Female; Humans; Male; Middle Aged; Prostat | 1987 |
[Clinical study on long-term cinoxacin therapy for outpatients with chronic complicated urinary tract infections].
Topics: Adult; Aged; Ambulatory Care; Chronic Disease; Cinoxacin; Drug Evaluation; Female; Humans; Male; Mid | 1985 |
Successful use of reduced dosage of cinoxacin in the treatment of recurrent urinary infection.
Topics: Adult; Cinoxacin; Humans; Microbial Sensitivity Tests; Middle Aged; Pyridazines; Recurrence; Urinary | 1985 |