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cinoxacin and Recrudescence

cinoxacin has been researched along with Recrudescence in 14 studies

Cinoxacin: Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
cinoxacin : A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.

Research Excerpts

ExcerptRelevanceReference
"We gave cinoxacin to 125 patients with initial and recurrent urinary tract infections to investigate the safety and efficacy of this new antimicrobial agent."9.05Cinoxacin therapy for urinary tract infections: therapeutic safety and efficacy. ( Cox, CE; Simmons, JR, 1982)
"In the TMP group one recurrence and in the CNO group two recurrences occurred during treatment, two recurrences being observed in each group during the follow-up period of 4-6 weeks."6.66Cinoxacin vs trimethoprim--safety and efficacy in the prophylaxis of uncomplicated urinary tract infections. ( Seppänen, J, 1988)
"Cinoxacin was as effective as trimethoprim-sulfamethoxazole without the emergence of resistant bacteria associated with trimethoprim-sulfamethoxazole."6.65Comparison of cinoxacin and trimethoprim-sulfamethoxazole in the treatment of urinary tract infections. ( Flynn, S; Jones, J; Schaeffer, AJ, 1981)
"Cinoxacin is an oral synthetic antibacterial agent, of the second generation quinolones group, with excellent efficacy in respiratory, intra-abdominal, pelvic, and skin and soft tissue infections."5.32Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction. ( Emiliani, F; Quercia, O; Rafanelli, S; Stefanini, GF, 2003)
"A randomized clinical study was conducted in order to compare the effectiveness of norfloxacin and cinoxacin in complicated urinary tract infections."5.06[Comparative evaluation of norfloxacin and cinoxacin in the therapy of complicated infections of the urinary tract]. ( Cristiano, P; Della Vittoria Scarpati, M; Iovene, MR; Manguso, L; Morelli, G; Simioli, F, 1989)
"We gave cinoxacin to 125 patients with initial and recurrent urinary tract infections to investigate the safety and efficacy of this new antimicrobial agent."5.05Cinoxacin therapy for urinary tract infections: therapeutic safety and efficacy. ( Cox, CE; Simmons, JR, 1982)
"In the TMP group one recurrence and in the CNO group two recurrences occurred during treatment, two recurrences being observed in each group during the follow-up period of 4-6 weeks."2.66Cinoxacin vs trimethoprim--safety and efficacy in the prophylaxis of uncomplicated urinary tract infections. ( Seppänen, J, 1988)
"cinoxacin were compared to 1 g."2.65A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection. ( Bucy, JG, 1981)
"Cinoxacin was as effective as trimethoprim-sulfamethoxazole without the emergence of resistant bacteria associated with trimethoprim-sulfamethoxazole."2.65Comparison of cinoxacin and trimethoprim-sulfamethoxazole in the treatment of urinary tract infections. ( Flynn, S; Jones, J; Schaeffer, AJ, 1981)
"Cinoxacin is an oral synthetic antibacterial agent, of the second generation quinolones group, with excellent efficacy in respiratory, intra-abdominal, pelvic, and skin and soft tissue infections."1.32Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction. ( Emiliani, F; Quercia, O; Rafanelli, S; Stefanini, GF, 2003)
"Ninety-seven patients with a history of recurrent bacteriuria were treated with cinoxacin in a dosage of either 250 mg (48 patients) or 500 mg (49 patients) 12-hourly for seven days."1.27Successful use of reduced dosage of cinoxacin in the treatment of recurrent urinary infection. ( Bax, R; Brumfitt, W; Hamilton-Miller, JM; Smith, GW, 1985)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Quercia, O1
Rafanelli, S1
Emiliani, F1
Stefanini, GF1
Scheckler, WE1
Burt, RA1
Paulson, DF1
Landes, RR2
Bucy, JG1
Cox, CE1
Simmons, JR1
Schaeffer, AJ2
Jones, JM1
Flynn, SS1
Finkelstein, LH1
Arsht, DB1
Manfrey, SJ1
Flynn, S1
Jones, J1
Cristiano, P1
Morelli, G1
Simioli, F1
Iovene, MR1
Della Vittoria Scarpati, M1
Manguso, L1
Seppänen, J1
Pfau, A1
Sacks, TG1
Shapiro, M1
Nihira, H1
Nakano, H1
Brumfitt, W1
Smith, GW1
Hamilton-Miller, JM1
Bax, R1

Reviews

1 review available for cinoxacin and Recrudescence

ArticleYear
[Prevention of recurrence of repetitious urinary tract infections in women].
    Nihon rinsho. Japanese journal of clinical medicine, 1986, Volume: 44, Issue:12

    Topics: Cinoxacin; Female; Humans; Pyridazines; Recurrence; Sex Factors; Urinary Tract Infections

1986

Trials

7 trials available for cinoxacin and Recrudescence

ArticleYear
Comparison of low-dose cinoxacin therapy and placebo in the prevention of recurrent urinary tract infections.
    The Journal of family practice, 1982, Volume: 15, Issue:5

    Topics: Adult; Aged; Cinoxacin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Middle Aged;

1982
Cinoxacin for treatment and prevention of recurrent urinary tract infection.
    Urology, 1981, Volume: 17, Issue:5

    Topics: Amoxicillin; Bacteria; Bacterial Infections; Cinoxacin; Clinical Trials as Topic; Double-Blind Metho

1981
A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection.
    The Journal of urology, 1981, Volume: 125, Issue:6

    Topics: Adult; Central Nervous System Diseases; Cinoxacin; Clinical Trials as Topic; Escherichia coli Infect

1981
Cinoxacin therapy for urinary tract infections: therapeutic safety and efficacy.
    Southern medical journal, 1982, Volume: 75, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Cinoxacin; Clinical Trials as Topic; Female

1982
Comparison of cinoxacin and trimethoprim-sulfamethoxazole in the treatment of urinary tract infections.
    The Journal of urology, 1981, Volume: 125, Issue:6

    Topics: Adult; Cinoxacin; Drug Combinations; Drug Resistance; Enterobacteriaceae; Enterobacteriaceae Infecti

1981
[Comparative evaluation of norfloxacin and cinoxacin in the therapy of complicated infections of the urinary tract].
    Minerva medica, 1989, Volume: 80, Issue:4

    Topics: Bacteria; Bacteriuria; Cinoxacin; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Male; Mi

1989
Cinoxacin vs trimethoprim--safety and efficacy in the prophylaxis of uncomplicated urinary tract infections.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:10

    Topics: Adolescent; Adult; Cinoxacin; Double-Blind Method; Female; Humans; Middle Aged; Pyridazines; Random

1988

Other Studies

6 other studies available for cinoxacin and Recrudescence

ArticleYear
Anaphylactic reaction to cinoxacin: report of one case associated with inferior acute myocardial infarction.
    European annals of allergy and clinical immunology, 2003, Volume: 35, Issue:2

    Topics: 4-Quinolones; Anaphylaxis; Anti-Infective Agents; Cinoxacin; Double-Blind Method; Humans; Inflammati

2003
Prophylactic efficacy of cinoxacin in recurrent urinary tract infection: biologic effects on the vaginal and fecal flora.
    The Journal of urology, 1982, Volume: 127, Issue:6

    Topics: Adult; Aged; Bacteriuria; Cinoxacin; Drug Evaluation; Feces; Female; Humans; Middle Aged; Pyridazine

1982
Cinoxacin and trimethoprim with sulfamethoxazole in the treatment of infections of the urinary tract: a clinical comparison.
    The Journal of the American Osteopathic Association, 1982, Volume: 81, Issue:12

    Topics: Adult; Aged; Bacterial Infections; Cinoxacin; Drug Combinations; Drug Evaluation; Female; Humans; Ma

1982
Long-term low dose cinoxacin therapy for the prevention of recurrent urinary tract infections.
    The Journal of urology, 1980, Volume: 123, Issue:1

    Topics: Adult; Cinoxacin; Double-Blind Method; Drug Evaluation; Female; Humans; Male; Middle Aged; Pilot Pro

1980
Prevention of recurrent urinary tract infections in premenopausal women by post-coital administration of cinoxacin.
    The Journal of urology, 1988, Volume: 139, Issue:6

    Topics: Adult; Cinoxacin; Coitus; Drug Administration Schedule; Escherichia coli Infections; Female; Humans;

1988
Successful use of reduced dosage of cinoxacin in the treatment of recurrent urinary infection.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 16, Issue:6

    Topics: Adult; Cinoxacin; Humans; Microbial Sensitivity Tests; Middle Aged; Pyridazines; Recurrence; Urinary

1985