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cinoxacin and Kidney Diseases

cinoxacin has been researched along with Kidney Diseases in 3 studies

Cinoxacin: Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
cinoxacin : A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Cinoxacin is a drug which, at very high doses, causes renal damage only in rats."1.27Effect of cinoxacin on cellular metabolism and p-aminohippurate transport in kidney cortical slices in terms of its nephrotoxic action. ( Gemba, M; Itoh, T; Komamura, T; Matsushima, Y; Miyata, K; Nakamura, M, 1983)
" The serum half-life of cinoxacin in patients with normal renal function was approximately 2."1.26Cinoxacin: pharmacokinetics and tolerance in patients with normal and impaired renal function. ( Frimodt-Möller, N; Madsen, PO; Maigaard, S; Welling, PG, 1979)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gemba, M1
Komamura, T1
Matsushima, Y1
Itoh, T1
Miyata, K1
Nakamura, M1
Ohkawa, M1
Sugata, T1
Sawaki, M1
Okasho, A1
Kuroda, K1
Yamada, H1
Maigaard, S1
Frimodt-Möller, N1
Welling, PG1
Madsen, PO1

Other Studies

3 other studies available for cinoxacin and Kidney Diseases

ArticleYear
Effect of cinoxacin on cellular metabolism and p-aminohippurate transport in kidney cortical slices in terms of its nephrotoxic action.
    Toxicology letters, 1983, Volume: 15, Issue:1

    Topics: Aminohippuric Acids; Animals; Biological Transport, Active; Cinoxacin; Female; Kidney; Kidney Cortex

1983
Pharmacokinetics of cinoxacin in normal volunteers and patients with impaired renal function.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Cinoxacin; Half-Life; Humans; Kidney Diseases; Kinetics; Pyridazines; Renal Dialy

1981
Cinoxacin: pharmacokinetics and tolerance in patients with normal and impaired renal function.
    Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:3

    Topics: Aged; Cinoxacin; Creatinine; Half-Life; Humans; Kidney Diseases; Kinetics; Middle Aged; Pyridazines;

1979