cinoxacin has been researched along with Granuloma in 1 studies
Cinoxacin: Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
cinoxacin : A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.
Granuloma: A relatively small nodular inflammatory lesion containing grouped mononuclear phagocytes, caused by infectious and noninfectious agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mutagenic and DNA-damaging activities of cinoxacin were evaluated in the rat granuloma pouch assay (GPA) in order to assess its genotoxic potential in vivo." | 7.67 | Absence of cinoxacin-induced DNA fragmentation and mutations in the rat granuloma pouch. ( Grillo, P; Maura, A; Pino, A, 1989) |
| "The mutagenic and DNA-damaging activities of cinoxacin were evaluated in the rat granuloma pouch assay (GPA) in order to assess its genotoxic potential in vivo." | 3.67 | Absence of cinoxacin-induced DNA fragmentation and mutations in the rat granuloma pouch. ( Grillo, P; Maura, A; Pino, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pino, A | 1 |
| Maura, A | 1 |
| Grillo, P | 1 |
1 other study available for cinoxacin and Granuloma
| Article | Year |
|---|---|
Absence of cinoxacin-induced DNA fragmentation and mutations in the rat granuloma pouch.
Topics: Animals; Cinoxacin; DNA; DNA Damage; Female; Granuloma; Kidney; Liver; Mutagenicity Tests; Mutation; | 1989 |