cinoxacin has been researched along with E coli Infections in 10 studies
Cinoxacin: Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
cinoxacin : A member of the class of cinnolines that is 6,7-methylenedioxycinnolin-4(1H)-one bearing an ethyl group at position 1 and a carboxylic acid group at position 3. An analogue of oxolinic acid, it has similar antibacterial actions. It was formerly used for the treatment of urinary tract infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a prospective, randomized, double-blind trial, ciprofloxacin (250 mg orally, twice daily) was compared with cinoxacin (500 mg orally, twice daily) in 60 patients with urinary tract infections." | 9.06 | Ciprofloxacin versus cinoxacin in therapy of urinary tract infections. A randomized, double-blind trial. ( Alpert, ML; Citron, DM; Ginsberg, BP; Goldstein, EJ; Greenway, FL; Kahn, RM, 1987) |
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 9.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "The antimicrobial activity of cinoxacin, 1-ethyl-4(1H)-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid, previously reported as compound 64716, was determined and compared with other antimicrobial agents at a dosage of 12 mg/kg once daily in a descending pyelonephritis rat model with Escherichia coli and Proteus mirabilis as infecting organisms." | 7.65 | Cinoxacin: effectiveness against experimental pyelonephritis in rats. ( Ensminger, PW; Gordee, RS; Holmes, DH, 1974) |
| "TWo dosage regimens of cinoxacin, 250 mg." | 6.65 | Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens. ( Cox, CE; Simmons, JR, 1981) |
| "In a prospective, randomized, double-blind trial, ciprofloxacin (250 mg orally, twice daily) was compared with cinoxacin (500 mg orally, twice daily) in 60 patients with urinary tract infections." | 5.06 | Ciprofloxacin versus cinoxacin in therapy of urinary tract infections. A randomized, double-blind trial. ( Alpert, ML; Citron, DM; Ginsberg, BP; Goldstein, EJ; Greenway, FL; Kahn, RM, 1987) |
| "A single-blind comparison was undertaken to evaluate 250 mg of cinoxacin and 100 mg of nitrofurantoin, both drugs being given four times a day, for the treatment of urinary tract infections." | 5.05 | Single-blind comparison of cinoxacin and nitrofurantoin in the treatment of urinary tract infection. ( Schneider, RE, 1982) |
| "A randomised single-blind clinical trial compared cinoxacin (500 mg every 12 hours) to co-trimoxazole (160 mg trimethoprim, 800 mg sulphamethoxazole every 12 hours) in the treatment of 63 patients with urinary tract infections." | 5.05 | Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections. ( de Jersey, P; Wooller, HO, 1982) |
| "The antimicrobial activity of cinoxacin, 1-ethyl-4(1H)-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid, previously reported as compound 64716, was determined and compared with other antimicrobial agents at a dosage of 12 mg/kg once daily in a descending pyelonephritis rat model with Escherichia coli and Proteus mirabilis as infecting organisms." | 3.65 | Cinoxacin: effectiveness against experimental pyelonephritis in rats. ( Ensminger, PW; Gordee, RS; Holmes, DH, 1974) |
| "cinoxacin were compared to 1 g." | 2.65 | A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection. ( Bucy, JG, 1981) |
| "TWo dosage regimens of cinoxacin, 250 mg." | 2.65 | Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens. ( Cox, CE; Simmons, JR, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chantrie, M | 1 |
| Bucy, JG | 1 |
| Cox, CE | 1 |
| Simmons, JR | 1 |
| Schneider, RE | 1 |
| de Jersey, P | 1 |
| Wooller, HO | 1 |
| Paulson, DF | 1 |
| Barnham, M | 1 |
| Gaya, H | 1 |
| Pfau, A | 1 |
| Sacks, TG | 1 |
| Shapiro, M | 1 |
| Goldstein, EJ | 1 |
| Kahn, RM | 1 |
| Alpert, ML | 1 |
| Ginsberg, BP | 1 |
| Greenway, FL | 1 |
| Citron, DM | 1 |
| Holmes, DH | 1 |
| Ensminger, PW | 1 |
| Gordee, RS | 1 |
6 trials available for cinoxacin and E coli Infections
| Article | Year |
|---|---|
A clinical comparison of cinoxacin and nalidixic acid in the treatment of urinary tract infection.
Topics: Adult; Central Nervous System Diseases; Cinoxacin; Clinical Trials as Topic; Escherichia coli Infect | 1981 |
Cinoxacin in therapy of urinary tract infections. Comparison of two dosage regimens.
Topics: Cinoxacin; Clinical Trials as Topic; Drug Administration Schedule; Enterobacteriaceae Infections; Es | 1981 |
Single-blind comparison of cinoxacin and nitrofurantoin in the treatment of urinary tract infection.
Topics: Adult; Age Factors; Aged; Cinoxacin; Drug Evaluation; Escherichia coli Infections; Female; Humans; M | 1982 |
Comparison of cinoxacin and co-trimoxazole in the treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Urinary; Bacteriuria; Cinoxacin; Clinical Trials as | 1982 |
Comparison of cinoxacin and nalidixic acid in patients with cystitis.
Topics: Adult; Aged; Cinoxacin; Cystitis; Escherichia coli Infections; Female; Humans; Male; Middle Aged; Na | 1982 |
Ciprofloxacin versus cinoxacin in therapy of urinary tract infections. A randomized, double-blind trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cinoxacin; Ciprofloxacin; Clinical | 1987 |
4 other studies available for cinoxacin and E coli Infections
| Article | Year |
|---|---|
[Cinobar, a new antimicrobial agent for the treatment of urinary infections].
Topics: Adult; Cinoxacin; Escherichia coli Infections; Female; Humans; Male; Nalidixic Acid; Pyridazines; Ra | 1980 |
In vitro susceptibility of urinary isolates of Escherichia coli to cinoxacin.
Topics: Cinoxacin; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Nalid | 1979 |
Prevention of recurrent urinary tract infections in premenopausal women by post-coital administration of cinoxacin.
Topics: Adult; Cinoxacin; Coitus; Drug Administration Schedule; Escherichia coli Infections; Female; Humans; | 1988 |
Cinoxacin: effectiveness against experimental pyelonephritis in rats.
Topics: Animals; Cinoxacin; Escherichia coli; Escherichia coli Infections; Female; Microbial Sensitivity Tes | 1974 |