cinnarizine and Necrosis

cinnarizine has been researched along with Necrosis* in 2 studies

Other Studies

2 other study(ies) available for cinnarizine and Necrosis

ArticleYear
[Effect of flunarizine on healing and necrosis of experimental autografts in the rat].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 1985, Volume: 17 Suppl

    The influence of flunarizine on flap necrosis has been studied in rats by means of an abdominal neurovascular island skin flap model. Four groups of six rats were treated in a pretreatment phase of one week and a medication phase of four weeks with either flunarizine (2.5 mg/kg) or a placebo. Rats with flunarizine treatment over the whole period showed a significantly faster healing and less necrosis than the placebo group. The group without flunarizine pretreatment showed similar results as the control group at the first week after surgery, but from the second week on, the flunarizine effect became manifest. The skin graft model clearly demonstrates the beneficial effects of flunarizine in the prevention of tissue necrosis.

    Topics: Animals; Cinnarizine; Flunarizine; Graft Survival; Male; Necrosis; Rats; Rats, Inbred Strains; Surgical Flaps; Vasodilator Agents; Wound Healing

1985
The action of flunarizine and lidoflazine on isoprenaline induced cardiac lesions.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 244, Issue:2

    Topics: Animals; Cinnarizine; Drug Antagonism; Female; Flunarizine; Heart; Isoproterenol; Lidoflazine; Myocardium; Necrosis; Piperazines; Rats

1980