cinnarizine and Edema
cinnarizine has been researched along with Edema* in 2 studies
Other Studies
2 other study(ies) available for cinnarizine and Edema
| Article | Year |
|---|---|
Effects of cinnarizine on different experimentally induced oedemas.
Experiments with male mice (28-32 g) of the CFLP strain showed that cinnarizine in doses of 2.5, 5.0 or 10.0 mg kg-1 significantly inhibited the extent of ear oedema induced by croton oil, capsaicin or dithranol, in a dose-dependent manner. In rats of the Wistar strain, oedema was induced in the hind paw by subplantar injection of carrageenin, and simultaneously by the application of croton oil to the inner surface of the ear. Preliminary cinnarizine treatment (5, 10 or 20 mg kg-1) inhibited the development of both types of oedema, to a statistically significant extent, in a dose-dependent manner. Topics: Administration, Topical; Animals; Anthralin; Anti-Inflammatory Agents; Blood Pressure; Calcium Channel Blockers; Capsaicin; Carrageenan; Cinnarizine; Croton Oil; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ear; Edema; Excipients; Foot; Hindlimb; Injections, Intraperitoneal; Irritants; Male; Mice; Rats; Rats, Wistar | 1999 |
[Anti-edematous effects of cinnarizine].
Experiments carried out with male mice (28-32 g) of CFLP strain have shown that cinnarizine significantly inhibits the extents of ear oedema induced by croton oil or capsaicin. In rats of Wistar strain, oedema was induced in the hind paw by subplantar injection of carrageenin, and simultaneously by the application of croton oil to the inner surface on the ear. Preliminary cinnarizine treatment inhibited the development of both types of oedema, to statistically significant extent. Topics: Animals; Cinnarizine; Edema; Male; Mice; Rats; Rats, Wistar | 1993 |