cinnarizine has been researched along with Asthma--Exercise-Induced* in 1 studies
1 review(s) available for cinnarizine and Asthma--Exercise-Induced
| Article | Year |
|---|---|
Airway smooth muscle, asthma, and calcium ions.
The intracellular concentration of free Ca2+ ions regulates many functions of cells including secretion, contraction, transport processes, and motility, among others. All of the pathogenetic processes in asthmatic airways are Ca2+-dependent phenomena: excitation-contraction coupling in smooth muscle, stimulus-secretion coupling in mast cells and mucous glands, nerve impulse initiation and conduction, and the development of inflammatory infiltration. Ca2+ entry blockers such as nifedipine and verapamil may affect exercise-induced asthma, airway tone, mast cell mediator release, and experimental anaphylaxis. Calmodulin-active drugs can inhibit smooth muscle contraction and mediator release. A new generation of Ca2+ antagonists may find a role in the management of asthma. Topics: Asthma; Asthma, Exercise-Induced; Autacoids; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Cinnarizine; Cromolyn Sodium; Epinephrine; Female; Humans; Inflammation; Ion Channels; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neutrophils; Theophylline | 1984 |