cinnamaldehyde has been researched along with Edema* in 1 studies
1 other study(ies) available for cinnamaldehyde and Edema
| Article | Year |
|---|---|
Toward the development of chemoprevention agents. Part 1: Design, synthesis, and anti-inflammatory activities of a new class of 2,5-disubstituted-dioxacycloalkanes.
A new class of 2,5-disubstituted-dioxacycloalkanes were designed and synthesized via stereoselective synthetic method as cancer chemoprevention agents. The anti-inflammatory activities of these compounds were tested using the xylene-induced mouse ear edema model. Some of these compounds exhibited comparable or better anti-inflammatory activities than that of aspirin suggesting that they can be further developed as potential anti-inflammatory drug lead compounds. In addition, treatment of these anti-inflammatory agents did not prolong tail bleeding time in mice. The structure/activity relationships were also analyzed among these compounds. Topics: Animals; Anti-Inflammatory Agents; Bleeding Time; Chemoprevention; Cycloparaffins; Drug Design; Edema; Male; Mice; Molecular Structure; Oxygen; Stereoisomerism; Structure-Activity Relationship | 2007 |