cimetidine and Zollinger-Ellison Syndrome studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Zollinger-Ellison Syndrome: A syndrome that is characterized by the triad of severe PEPTIC ULCER, hypersecretion of GASTRIC ACID, and GASTRIN-producing tumors of the PANCREAS or other tissue (GASTRINOMA). This syndrome may be sporadic or be associated with MULTIPLE ENDOCRINE NEOPLASIA TYPE 1.

Research Excerpts

Excerpt	Relevance	Reference
"The ability of famotidine to control gastric acid hypersecretion in 32 patients with Zollinger-Ellison syndrome was compared to that of cimetidine or ranitidine."	9.06	Famotidine: effective treatment of Zollinger-Ellison syndrome. ( Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; Vinayek, R; Wank, SA, 1987)
"The treatment of gastric ulcer by the H2-receptor-antagonist Cimetidine results in an ulcer healing rate of 60 to 80% during a 4 to 6 weeks therapy cure."	9.04	[Treatment of stomach ulcer and of Zollinger-Ellison syndrome with cimetidine]. ( Brunner, H, 1978)
"Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease."	8.77	Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986)
"We studied the effect of omeprazole, a benzimidazole inhibitor of gastric acid secretion, in patients with Zollinger-Ellison syndrome."	7.67	Omeprazole in Zollinger-Ellison syndrome. Effects of a single dose and of long-term treatment in patients resistant to histamine H2-receptor antagonists. ( Jansen, JB; Lambers, CB; Lind, T; Moberg, S; Olbe, L, 1984)
"The inhibitory effect of omeprazole, a benzimidazole derivative, on gastric acid secretion was investigated in seven patients with Zollinger-Ellison syndrome resistant to treatment with large doses of histamine H2-receptor antagonists administered alone or in combination with pirenzepine."	7.67	Effectiveness of omeprazole in seven patients with Zollinger-Ellison syndrome resistant to histamine H2-receptor antagonists. ( Bader, JP; Cortot, A; Delchier, JC; Goldfain, D; Isal, JP; Mignon, M; Soule, JC; Travers, B, 1986)
"Famotidine, a new, potent, long-acting histamine H2-receptor antagonist was compared with cimetidine and ranitidine in 9 patients with Zollinger-Ellison syndrome."	7.67	Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome. ( Cherner, JA; Chremos, AN; Ciarleglio, CA; Collen, MJ; Cornelius, MJ; Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; McArthur, KE, 1985)
"A patient with Zollinger-Ellison syndrome appeared initially to respond to cimetidine with a reduction in gastric acid secretion."	7.66	Zollinger-Ellison syndrome unresponsive to cimetidine. ( Groarke, JF; Haggstrom, GD; Halpern, NB; Hirschowitz, BI, 1979)
"Patients with Zollinger-Ellison syndrome whose gastric acid secretion or symptoms were not controlled by cimetidine in conventional dosage were selected for studies of responsiveness of their acid secretion to increasing doses of cimetidine, used either alone or in combination with a long-acting anticholinergic agent, isopropamide iodide."	7.66	Effect of isopropamide on response to oral cimetidine in patients with Zollinger--Ellison syndrome. ( Hyman, PE; McCarthy, DM, 1982)
"A patient with Zollinger-Ellison syndrome was treated by an H2-receptor blocking drug (cimetidine)."	7.66	Plasma-secretin in management of cimetidine therapy for Zollinger-Ellison syndrome. ( Greenstein, RJ; Straus, E; Yalow, RS, 1978)
"In a patient with the Zollinger-Ellison syndrome who had undergone vagotomy, pyloroplasty and, later, gastrojejunostomy, epigastric pain and stomal ulceration recurred despite the use of high doses (2700 mg/d) of cimetidine."	7.66	Cimetidine-resistant Zollinger-Ellison syndrome: successful management with ranitidine. ( Greenberg, GR; Habal, FM; Soldin, SJ, 1983)
"Both the pharmacokinetics and the pharmacodynamics of cimetidine were investigated in three patients with Zollinger-Ellison syndrome, who were unresponsive to conventional dosing regimens."	7.66	Failure of cimetidine in Zollinger-Ellison syndrome. ( Adamonis, AJ; Dreyer, M; Madura, M; Olinger, EJ; Schentag, JJ; Ziemniak, JA, 1983)
"From 1977 to 1983 we used cimetidine as primary therapy for 17 patients with the Zollinger-Ellison syndrome."	7.66	Cimetidine in the treatment of Zollinger-Ellison syndrome. ( Deveney, CW; Stein, S; Way, LW, 1983)
"Inhibition of gastric acid secretion by the combined use of cimetidine and pirenzepin has been studied in 5 cases of Zollinger-Ellison syndrome."	7.66	Interest of a combined antisecretory treatment, cimetidine and pirenzepin, in the management of severe forms of Zollinger-Ellison syndrome. ( Bonfils, S; Dupas, JL; Galmiche, JP; Mignon, M; Vallot, T, 1980)
"Thirteen patients with Zollinger-Ellison syndrome (ZES) were treated with cimetidine."	7.66	Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome. ( Bonfils, S; Gratton, J; Mignon, M, 1979)
"The first case of the Zollinger-Ellison syndrome treated from the outset continuously for more than a year with the histamine H2-receptor antagonist cimetidine is reported."	7.65	Cimetidine in the management of the Zollinger-Ellison syndrome. ( Davies, HL; Larkworthy, W, 1977)
" The altered cimetidine effectiveness was not associated with reduced oral bioavailability and serum calcium was unchanged."	5.27	Development of cimetidine resistance in the Zollinger-Ellison syndrome. ( Andersen, BN; Larsen, NE; Rune, SJ; Worning, H, 1985)
"Treatment with cimetidine has produced satisfactory control of his symptoms for 16 months, and is an acceptable alternative to total gastrectomy in childhood."	5.26	Zollinger-Ellison syndrome in a child: medical treatment with cimetidine. ( Atwell, JD; Drake, DP; Maciver, AG, 1980)
"The histamine (H2)-receptor antagonist famotidine was compared with ranitidine and cimetidine in its ability to control gastric acid hypersecretion in 33 patients with gastric hypersecretory states (32 patients with Zollinger-Ellison syndrome and one patient with idiopathic hypersecretion)."	5.06	Famotidine in the therapy of gastric hypersecretory states. ( Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; Slaff, JI; Vinayek, R; Wank, SA, 1986)
"The ability of famotidine to control gastric acid hypersecretion in 32 patients with Zollinger-Ellison syndrome was compared to that of cimetidine or ranitidine."	5.06	Famotidine: effective treatment of Zollinger-Ellison syndrome. ( Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; Vinayek, R; Wank, SA, 1987)
"Ranitidine is an H2-receptor antagonist that was released recently for use in the treatment of acute duodenal ulcer disease, Zollinger-Ellison syndrome, and systemic mastocytosis with gastric hypersecretion."	5.05	Ranitidine. ( Strum, WB, 1983)
"We studied the effect of intravenous administration of a gastrin-receptor antagonist (proglumide) on gastric acid secretion and serum gastrin in three patients with Zollinger-Ellison syndrome."	5.05	The effect of a gastrin-receptor antagonist on gastric acid secretion and serum gastrin in the Zollinger-Ellison syndrome. ( Jansen, JB; Lamers, CB, 1983)
"The treatment of gastric ulcer by the H2-receptor-antagonist Cimetidine results in an ulcer healing rate of 60 to 80% during a 4 to 6 weeks therapy cure."	5.04	[Treatment of stomach ulcer and of Zollinger-Ellison syndrome with cimetidine]. ( Brunner, H, 1978)
"H2-Histamine receptor blocking agents metiamide and cimetidine were assessed in seven patients with Zollinger-Ellison syndrome (serum gastrin greater than 300 microgram/ml, basal acid output greater than 15 meq/h, ratio of basal acid output to maximal acid output greater than 0."	5.04	H2-Histamine receptor blocking agents in the Zollinger-Ellison syndrome. Experience in seven cases and implications for long-term therapy. ( Gardner, JD; Long, BW; May, RJ; McCarthy, DM; Olinger, EJ, 1977)
"Inhibition of acid secretion was investigated in 5 patients with Zollinger-Ellison syndrome and 12 patients with duodenal ulcer after administration of 200 mg cimetidine alone and combined with 50 mg methanthelinebromide."	5.04	[Long-term suppression of H+ secretion through a combination of cimetidine and methanthelinbromide (author's transl)]. ( Fritsch, WP; Hengels, KJ; Müller, JE; Scholten, T, 1979)
"Several histamine H2 receptor antagonists and the H+,K(+)-ATPase inhibitor, omeprazole, have been shown to be capable of controlling gastric acid secretion safely and effectively in patients with Zollinger-Ellison syndrome."	4.77	Recent advances in the management of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome. ( Gardner, JD; Jensen, RT; Maton, PN, 1989)
"Cimetidine and ranitidine are specific and potent H2-receptor antagonists widely used in the effective therapy of peptic ulcer disease."	4.77	Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. ( Cheah, LS; Gwee, MC, 1986)
"Cimetidine therapy has proved to be effective in healing most duodenal ulcers and in reducing the frequency of reulceration."	4.76	Cimetidine. I. Developments, pharmacology, and efficacy. ( Freston, JW, 1982)
"Cimetidine is a specific competitive histamine H2-receptor antagonist which effectively inhibits gastric acid secretion and is advocated for the treatment of chronic peptic ulceration, haemorrhage from erosive gastritis, and the control of gastric hypersecretion and peptic ulceration in the Zollinger-Ellison syndrome."	4.75	Cimetidine: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1978)
"We studied the effect of omeprazole, a benzimidazole inhibitor of gastric acid secretion, in patients with Zollinger-Ellison syndrome."	3.67	Omeprazole in Zollinger-Ellison syndrome. Effects of a single dose and of long-term treatment in patients resistant to histamine H2-receptor antagonists. ( Jansen, JB; Lambers, CB; Lind, T; Moberg, S; Olbe, L, 1984)
" Similarly we have studied the role of gastric acid deregulation in achlorhydria, the Zollinger-Ellison syndrome, and duodenal ulcer, and the influence of the antacid drugs cimetidine and ranitidine under duodenal ulcer conditions."	3.67	A model study of the regulation of gastric acid secretion. ( de Goede, J; Hekkens, W; Van Duijn, B; Verveen, AA; Ypey, DL, 1989)
"Famotidine, a new, potent, long-acting histamine H2-receptor antagonist was compared with cimetidine and ranitidine in 9 patients with Zollinger-Ellison syndrome."	3.67	Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome. ( Cherner, JA; Chremos, AN; Ciarleglio, CA; Collen, MJ; Cornelius, MJ; Gardner, JD; Howard, JM; Jensen, RT; Maton, PN; McArthur, KE, 1985)
"The inhibitory effect of omeprazole, a benzimidazole derivative, on gastric acid secretion was investigated in seven patients with Zollinger-Ellison syndrome resistant to treatment with large doses of histamine H2-receptor antagonists administered alone or in combination with pirenzepine."	3.67	Effectiveness of omeprazole in seven patients with Zollinger-Ellison syndrome resistant to histamine H2-receptor antagonists. ( Bader, JP; Cortot, A; Delchier, JC; Goldfain, D; Isal, JP; Mignon, M; Soule, JC; Travers, B, 1986)
"A study has been made of the gastric secretions from a patient with Zollinger-Ellison syndrome without peptic ulceration, before and after treatment with cimetidine."	3.67	The nature of gastric secretions in a patient with Zollinger-Ellison syndrome without peptic ulceration. ( Clamp, JR; Fairclough, PD, 1986)
"A 49-year-old woman treated with cimetidine 300 mg tid for more than 18 months for Zollinger-Ellison syndrome experienced lethargy, dizziness, ataxia, and auditory and visual hallucinations after receiving triazolam 0."	3.67	Central nervous system toxicity associated with concurrent use of triazolam and cimetidine. ( Britton, ML; Waller, ES, 1985)
"Clinical and endoscopic findings were compared with 24-hr pH profiles in 8 patients with Zollinger-Ellison syndrome (ZES), who were being treated, during consecutive periods, with doses of cimetidine or ranitidine."	3.66	Evaluation of antisecretory drug therapy of Zollinger-Ellison syndrome (ZES) using 24-hour pH monitoring. ( Bonfils, S; Mazure, R; Mignon, M; Vallot, T, 1983)
"Review of a 5 year clinical experience with the histamine H2-receptor antagonists metiamide, cimetidine, and ranitidine in 20 patients with Zollinger-Ellison syndrome disclosed a treatment failure rate of 50 percent."	3.66	Failure of histamine H2-receptor antagonist therapy in Zollinger-Ellison syndrome. ( Ippoliti, AF; Passaro, E; Stabile, BE; Walsh, JH, 1983)
"Thirteen patients with Zollinger-Ellison syndrome (ZES) were treated with cimetidine."	3.66	Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome. ( Bonfils, S; Gratton, J; Mignon, M, 1979)
"A patient with Zollinger-Ellison syndrome appeared initially to respond to cimetidine with a reduction in gastric acid secretion."	3.66	Zollinger-Ellison syndrome unresponsive to cimetidine. ( Groarke, JF; Haggstrom, GD; Halpern, NB; Hirschowitz, BI, 1979)
"Sixty-one cases of the Zollinger-Ellison syndrome, encountered over a 2-year period, have been treated with cimetidine, half of them for over 1 year."	3.66	Report on the United States experience with cimetidine in Zollinger-Ellision syndrome and other hypersecretory states. ( McCarthy, DM, 1978)
"Treatment of Zollinger-Ellison syndrome with cimetidine is justified by prior pharmacological studies; close survey of the patients is necessary, using clinical (endoscopic control of ulcer; diarrhea) and biological (BOA measurements and assessment of cimetidine efficiency) criteria."	3.66	[Prolonged treatment of Zollinger-Ellison by cimetidine (author's transl)]. ( Bonfils, S; Gratton, J; Mignon, M; Rigaud, D, 1979)
"Cimetidine was studied in 8 cases of Zollinger-Ellison syndrome."	3.66	[Histamine H-2 receptor antagonists and medical treatment of Zollinger-Ellison syndrome]. ( Bonfils, S; Kloeti, G; Mignon, M, 1978)
" The use of cimetidine or frequent administration of a potent liquid antacid ensures initial healing of duodenal ulcers in 75% to 90% of patients."	3.66	An aggressive approach to the medical management of peptic ulcer disease. ( Achkar, E; Fleshler, B, 1981)
"The topical nature of the treatment of Zollinger-Ellison syndrome arises from the alternatives to total gastrectomy, namely medical management with cimetidine, and tumorectomy."	3.66	[Current therapeutic problems in the Zollinger-Ellison syndrome. Personal cases]. ( Cavina, E, 1982)
"Histamine H2-receptor antagonists metiamide and cimetidine were used in the treatment of severe peptic ulceration in Zollinger-Ellison syndrome."	3.65	[Treatment of peptic ulcer in the Zollinger-Ellison syndrome with histamine H2-receptor antagonists (author's transl)]. ( Fritsch, WP; Hausamen, TU; Jungblut, R; Scholten, T; Strohmeyer, G, 1977)
" The incidence of serious adverse events reported in comparative short-term studies with H2-receptor antagonists and placebo were similar."	2.66	The clinical safety of omeprazole. ( Sölvell, L, 1989)
"Cimetidine is an H2-receptor antagonist that is capable of marked suppression of gastric acid and pepsin secretion."	2.64	Cimetidine. H2-receptor blockade in gastrointestinal disease. ( Schlippert, W, 1978)
"Useful indications are treatment of gastric ulcer and pnacreatic insufficiency."	2.36	H2-receptor antagonists in perspective. ( Cortot, A; Malagelada, JR, 1978)
" Even under long-term administration no severe organic side effect occured with the drug which generally is well tolerated."	2.36	[Review: cimetidine: mode of action and clinical efficacy in various gastrointestinal diseases (author's transl)]. ( Hotz, J, 1980)
"Omeprazole was well tolerated, and the incidence of clinical and laboratory adverse experiences was similar in patients receiving omeprazole, placebo, cimetidine, or ranitidine."	1.28	Comparative tolerability profile of omeprazole in clinical trials. ( Bradstreet, DC; Simon, TJ, 1991)
"cimetidine was safe and effective in achieving this degree of control for up to 83 days."	1.28	Parenteral antisecretory drug therapy in patients with Zollinger-Ellison syndrome. ( Frank, WO; Gardner, JD; Jensen, RT; Maton, PN; Norton, JA; Saeed, ZA; Young, MD, 1989)
"Fundic argyrophil carcinoid tumors developed in the course of a 5-year continuous treatment with high dosages of H2-antagonists in a well-documented case of Zollinger-Ellison syndrome with primary hyperparathyroidism, high basal acid output, and serum gastrin."	1.27	Development of gastric argyrophil carcinoid tumors in a case of Zollinger-Ellison syndrome with primary hyperparathyroidism during long-term antisecretory treatment. ( Bonfils, S; Bonnefond, A; Labeille, D; Lehy, T; Mignon, M; Ruszniewski, P, 1987)
" The altered cimetidine effectiveness was not associated with reduced oral bioavailability and serum calcium was unchanged."	1.27	Development of cimetidine resistance in the Zollinger-Ellison syndrome. ( Andersen, BN; Larsen, NE; Rune, SJ; Worning, H, 1985)
"Pneumopericardium was discovered, and at autopsy a large penetrating gastrojejunal ulcer was demonstrated."	1.26	Zollinger-Ellison syndrome with pneumopericardium. ( Akgun, S; Green, JD; Pierozak, RF; Sharma, SM, 1979)
"Cimetidine may cause mental confusion and should be used with caution and in reduced dosage in the presence of hepatic or renal disease, or both, and in elderly patients."	1.26	Cimetidine: clinical uses and possible side effects. ( Babb, RR, 1980)

Timeframe	Studies, this research(%)	All Research%
pre-1990	177 (94.65)	18.7374
1990's	10 (5.35)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Trial	Enrollment	Study Type	Start Date	Status
Medical Therapy of Zollinger-Ellison Syndrome[NCT00001241]	0 participants	Observational	1989-01-27	Completed
Diagnostic Evaluation of Patients With Suspected Abnormalities of Gastric Secretion[NCT00001240]	0 participants	Observational	1989-01-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
[Review: cimetidine: mode of action and clinical efficacy in various gastrointestinal diseases (author's transl)]. Zeitschrift fur Gastroenterologie, 1980, Volume: 18, Issue:7 Topics: Acute Disease; Cimetidine; Duodenal Ulcer; Exocrine Pancreatic Insufficiency; Gastric Acid; Gastroes	1980
[Clinical importance of antagonists of histamine H2 receptors in gastroenterology]. La Clinica terapeutica, 1984, Mar-31, Volume: 108, Issue:6 Topics: Cimetidine; Drug Resistance; Duodenal Ulcer; Gastroesophageal Reflux; Histamine H2 Antagonists; Huma	1984
[Zollinger-Ellison syndrome. Experience in 14 cases and a review of the recent literature]. Medicina clinica, 1984, Oct-27, Volume: 83, Issue:13 Topics: Adult; Cimetidine; Esophagitis; Female; Gastrins; Humans; Male; Middle Aged; Multiple Endocrine Neop	1984
Histamine H2-receptor antagonists and gastric acid secretion. Pharmacology & therapeutics, 1984, Volume: 26, Issue:2 Topics: Burimamide; Chemical Phenomena; Chemistry; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastric	1984
[Current status of treatment in the Zollinger-Ellison syndrome]. Medicina clinica, 1983, Feb-05, Volume: 80, Issue:3 Topics: Cimetidine; Gastrectomy; Gastric Acid; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Stre	1983
[Ranitidine]. Medicina clinica, 1983, Jul-02, Volume: 81, Issue:4 Topics: Anti-Ulcer Agents; Chemical Phenomena; Chemistry; Cimetidine; Duodenal Ulcer; Gastroesophageal Reflu	1983
Cimetidine vs ranitidine. The Journal of the Kansas Medical Society, 1983, Volume: 84, Issue:12 Topics: Cimetidine; Duodenal Ulcer; Humans; Ranitidine; Zollinger-Ellison Syndrome	1983
[Current trends in the treatment of Zollinger-Ellison syndrome]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Aug-01, Volume: 38, Issue:31 Topics: Cimetidine; Evaluation Studies as Topic; Gastrectomy; Humans; Ranitidine; Vagotomy, Proximal Gastric	1983
[Zollinger-Ellison syndrome]. Wiener klinische Wochenschrift, 1984, Feb-17, Volume: 96, Issue:4 Topics: Benzimidazoles; Calcium; Cimetidine; Diarrhea; Duodenal Ulcer; Female; Fluorouracil; Gastrectomy; Ga	1984
Treatment of the Zollinger-Ellison syndrome. A 25 year assessment. American journal of surgery, 1982, Volume: 143, Issue:3 Topics: Cimetidine; Gastrectomy; Gastrins; Guanidines; Humans; Neoplasm Metastasis; Retrospective Studies; S	1982
Cimetidine. I. Developments, pharmacology, and efficacy. Annals of internal medicine, 1982, Volume: 97, Issue:4 Topics: Chemical Phenomena; Chemistry; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastric Acid; Gastro	1982
[Pharmacotherapy of peptic ulcer]. Klinicheskaia meditsina, 1980, Volume: 58, Issue:1 Topics: Antacids; Anti-Ulcer Agents; Carbenoxolone; Cimetidine; Drug Evaluation; Humans; Parasympatholytics;	1980
The place of surgery in the Zollinger-Ellison syndrome. The New England journal of medicine, 1980, Jun-12, Volume: 302, Issue:24 Topics: Cimetidine; Gastrectomy; Gastric Juice; Gastrins; Humans; Hyperplasia; Neoplasm Metastasis; Postoper	1980
Cimetidine in clinical use. A review. The Netherlands journal of medicine, 1980, Volume: 23, Issue:5 Topics: Cimetidine; Duodenal Ulcer; Gastric Acid; Gastrins; Guanidines; Humans; Kinetics; Pancreatitis; Time	1980
The impact of cimetidine on the treatment of acid-peptic disease. Primary care, 1981, Volume: 8, Issue:2 Topics: Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastritis; Gastrointestinal Hemorrhage; Guanidines;	1981
Cimetidine in elderly patients: review of uses and risks. Journal of the American Geriatrics Society, 1982, Volume: 30, Issue:3 Topics: Administration, Oral; Aged; Antacids; Chemical Phenomena; Chemistry; Chlordiazepoxide; Cimetidine; D	1982
Zollinger-Ellison syndrome. Annual review of medicine, 1982, Volume: 33 Topics: Adult; Antineoplastic Agents; Cimetidine; Diagnosis, Differential; Gastrectomy; Gastric Acid; Gastri	1982
[25 years of gastric acid blockers]. Nederlands tijdschrift voor geneeskunde, 1999, Dec-11, Volume: 143, Issue:50 Topics: Anti-Ulcer Agents; Cimetidine; Dyspepsia; Gastroesophageal Reflux; Histamine H2 Antagonists; Humans;	1999
H2-receptor antagonists in perspective. Mayo Clinic proceedings, 1978, Volume: 53, Issue:3 Topics: Cimetidine; Double-Blind Method; Duodenal Ulcer; Gastroesophageal Reflux; Gastrointestinal Hemorrhag	1978
H2 receptor antagonists. American journal of hospital pharmacy, 1978, Volume: 35, Issue:2 Topics: Cimetidine; Gastric Juice; Histamine H2 Antagonists; Humans; Metiamide; Peptic Ulcer; Zollinger-Elli	1978
[Cimetidine: a review (author's transl)]. Revista medica de Chile, 1979, Volume: 107, Issue:3 Topics: Cimetidine; Esophagitis, Peptic; Gastroesophageal Reflux; Gastrointestinal Hemorrhage; Guanidines; H	1979
[The therapeutic importance of cimetidine (Tagamet) (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1978, Nov-03, Volume: 120, Issue:44 Topics: Adult; Cimetidine; Diarrhea; Female; Galactorrhea; Gastritis; Guanidines; Gynecomastia; Headache; Hu	1978
Cimetidine: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease. Drugs, 1978, Volume: 15, Issue:2 Topics: Acute Disease; Animals; Cimetidine; Duodenal Ulcer; Gastric Juice; Gastrins; Gastrointestinal Hemorr	1978
[Cimetidine; new hope for ulcer patients?]. Nederlands tijdschrift voor geneeskunde, 1978, Jun-17, Volume: 122, Issue:24 Topics: Burimamide; Cimetidine; Creatinine; Duodenal Ulcer; Esophagitis, Peptic; Gastric Juice; Gastritis; G	1978
[Cimetidine. Clinical pharmacology and toxicity (author's transl)]. La Nouvelle presse medicale, 1978, May-20, Volume: 7, Issue:20 Topics: Cimetidine; Gastric Juice; Gastrins; Gastrointestinal Hemorrhage; Guanidines; Humans; Peptic Ulcer;	1978
Drug therapy: Cimetidine. The New England journal of medicine, 1978, Nov-02, Volume: 299, Issue:18 Topics: Acute Disease; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer	1978
[Gastrointestinal hormones. Current knowledge]. Medizinische Klinik, 1979, Feb-02, Volume: 74, Issue:5 Topics: Bombesin; Cholecystokinin; Cimetidine; Epidermal Growth Factor; Gastric Inhibitory Polypeptide; Gast	1979
The Zollinger--Ellison syndrome. Clinics in endocrinology and metabolism, 1979, Volume: 8, Issue:2 Topics: Amino Acid Sequence; Child; Cimetidine; Eating; Gastrectomy; Gastrins; Humans; Zollinger-Ellison Syn	1979
Cimetidine in the management of peptic ulcer disease. The Surgical clinics of North America, 1979, Volume: 59, Issue:5 Topics: Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastrectomy; Gastritis; Gastrointestinal Hemorrhage	1979
A case report of Zollinger Ellison syndrome and review of the literature. The Japanese journal of surgery, 1991, Volume: 21, Issue:1 Topics: Adult; Cimetidine; Gastrectomy; Humans; Male; Zollinger-Ellison Syndrome	1991
[Gastrin-producing neoformations (Zollinger-Ellison syndrome)]. Klinicheskaia meditsina, 1990, Volume: 68, Issue:11 Topics: Adult; Aged; Child; Cimetidine; Diagnosis, Differential; Famotidine; Gastrectomy; Gastrins; Humans;	1990
The current status of the surgical and medical treatment of the Zollinger-Ellison syndrome. Surgery annual, 1990, Volume: 22 Topics: Anti-Ulcer Agents; Cimetidine; Famotidine; Humans; Prospective Studies; Ranitidine; Zollinger-Elliso	1990
Recent advances in the management of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome. Gastroenterology clinics of North America, 1989, Volume: 18, Issue:4 Topics: Cimetidine; Famotidine; Gastric Acid; Histamine H2 Antagonists; Humans; Nizatidine; Omeprazole; Para	1989
Gastrinoma in a mesenteric lymph node. The American journal of gastroenterology, 1989, Volume: 84, Issue:6 Topics: Adult; Cimetidine; Gastrins; Humans; Lymph Nodes; Male; Mesentery; Zollinger-Ellison Syndrome	1989
Actions of cimetidine and ranitidine at some cholinergic sites: implications in toxicology and anesthesia. Life sciences, 1986, Aug-04, Volume: 39, Issue:5 Topics: Anesthesia; Animals; Antihypertensive Agents; Bradycardia; Cholinesterase Inhibitors; Cimetidine; Co	1986
Medical treatment of peptic ulcers. Surgery annual, 1985, Volume: 17 Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzimidazoles; Bismuth; Cimetidine; Humans; Omeprazole; Para	1985

Article	Year
Cimetidine now. Lancet (London, England), 1981, Apr-18, Volume: 1, Issue:8225 Topics: Cimetidine; Clinical Trials as Topic; Esophagitis; Guanidines; Humans; Peptic Ulcer; Zollinger-Ellis	1981
Testing antisecretory drugs in Zollinger-Ellison syndrome: problems and limits in pharmacological studies. Digestive diseases and sciences, 1982, Volume: 27, Issue:4 Topics: Cimetidine; Clinical Trials as Topic; Humans; Quaternary Ammonium Compounds; Zollinger-Ellison Syndr	1982
Comparison of the effectiveness of ranitidine and cimetidine in inhibiting acid secretion in patients with gastric hypersecretory states. The American journal of medicine, 1984, Nov-19, Volume: 77, Issue:5B Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, C	1984
Ranitidine. JAMA, 1983, Oct-14, Volume: 250, Issue:14 Topics: Aged; Animals; Chemical Phenomena; Chemistry; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer;	1983
The effect of a gastrin-receptor antagonist on gastric acid secretion and serum gastrin in the Zollinger-Ellison syndrome. Journal of clinical gastroenterology, 1983, Volume: 5, Issue:1 Topics: Adult; Cimetidine; Female; Gastric Acid; Gastrins; Glutamine; Humans; Male; Middle Aged; Proglumide;	1983
[Cimetidine]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Feb-04, Volume: 35, Issue:5 Topics: Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Gastrointestinal Hemorrhage; Guanidines; Human	1980
[Cimetidine]. AMB : revista da Associacao Medica Brasileira, 1981, Volume: 27, Issue:10 Topics: Cimetidine; Clinical Trials as Topic; Gastric Acid; Gastrointestinal Hemorrhage; Guanidines; Humans;	1981
H2-Histamine receptor blocking agents in the Zollinger-Ellison syndrome. Experience in seven cases and implications for long-term therapy. Annals of internal medicine, 1977, Volume: 87, Issue:6 Topics: Adult; Aged; Chlorides; Cimetidine; Clinical Trials as Topic; Female; Gastric Juice; Histamine H2 An	1977
[Long-term suppression of H+ secretion through a combination of cimetidine and methanthelinbromide (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1979, Dec-28, Volume: 104, Issue:52 Topics: Adult; Cimetidine; Drug Therapy, Combination; Duodenal Ulcer; Female; Guanidines; Humans; Male; Quat	1979
Safety and efficacy of cimetidine treatment. Scottish medical journal, 1977, Volume: 22, Issue:4 Topics: Animals; Cimetidine; Clinical Trials as Topic; Dogs; Drug Evaluation, Preclinical; Guanidines; Human	1977
[What is certain in the treatment of peptic ulcer using cimetidine?]. Der Internist, 1977, Volume: 18, Issue:12 Topics: Acute Disease; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer; Gastrointestin	1977
[Cimetidine, II. Therapeutic trials]. La Nouvelle presse medicale, 1978, May-27, Volume: 7, Issue:21 Topics: Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer; Esophagitis, Peptic; Gastroin	1978
Drug therapy: Cimetidine. The New England journal of medicine, 1978, Nov-02, Volume: 299, Issue:18 Topics: Acute Disease; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Drug Evaluation; Duodenal Ulcer	1978
Cimetidine. H2-receptor blockade in gastrointestinal disease. Archives of internal medicine, 1978, Volume: 138, Issue:8 Topics: Animals; Cimetidine; Dogs; Duodenal Ulcer; Gastroesophageal Reflux; Gastrointestinal Diseases; Guani	1978
[Treatment of stomach ulcer and of Zollinger-Ellison syndrome with cimetidine]. Acta medica Austriaca, 1978, Volume: 5, Issue:2 Topics: Antacids; Carbenoxolone; Cimetidine; Double-Blind Method; Gastric Juice; Gastric Mucosa; Gastrins; G	1978
Effects of curative gastrinoma resection on gastric secretory function and antisecretory drug requirement in the Zollinger-Ellison syndrome. Gastroenterology, 1992, Volume: 102, Issue:3 Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Duodenal Neoplasms; Famotidine; Female; F	1992
The clinical safety of omeprazole. Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166 Topics: Cimetidine; Clinical Trials as Topic; Esophagitis, Peptic; Humans; Liver Function Tests; Omeprazole;	1989
Famotidine in the therapy of gastric hypersecretory states. The American journal of medicine, 1986, Oct-24, Volume: 81, Issue:4B Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; Famotidine; Female; Ga	1986
Famotidine: effective treatment of Zollinger-Ellison syndrome. Journal of clinical gastroenterology, 1987, Volume: 9 Suppl 2 Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid; Histami	1987

Article	Year
[H2 receptor blockaders: domains for oral use. Indications for cimetidine and ranitidine in gastroenterology]. Fortschritte der Medizin, 1984, Feb-23, Volume: 102, Issue:8 Topics: Administration, Oral; Cimetidine; Duodenitis; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency	1984
Ranitidine and cimetidine in Zollinger-Ellison syndrome. British journal of clinical pharmacology, 1980, Volume: 10, Issue:2 Topics: Adult; Cimetidine; Furans; Guanidines; Histamine H2 Antagonists; Humans; Male; Ranitidine; Zollinger	1980
[Interest of ranitidine, a new H2 receptor antagonist in the treatment of Zollinger-Ellison syndrome (author's transl)]. Gastroenterologie clinique et biologique, 1981, Volume: 5, Issue:1 Topics: Adult; Cimetidine; Furans; Histamine H2 Antagonists; Humans; Hydrogen-Ion Concentration; Male; Ranit	1981
Effect of isopropamide on response to oral cimetidine in patients with Zollinger--Ellison syndrome. Digestive diseases and sciences, 1982, Volume: 27, Issue:4 Topics: Aged; Cimetidine; Drug Resistance; Drug Therapy, Combination; Female; Gastric Acid; Guanidines; Huma	1982
Reliability of symptoms in assessing control of gastric acid secretion in patients with Zollinger-Ellison syndrome. Gastroenterology, 1983, Volume: 84, Issue:1 Topics: Adult; Aged; Cimetidine; Female; Gastric Acid; Gastric Acidity Determination; Humans; Male; Middle A	1983
Uncertainties in the management of the Zollinger-Ellison Syndrome. Gastroenterology, 1983, Volume: 84, Issue:1 Topics: Cimetidine; Furans; Histamine H2 Antagonists; Humans; Parasympatholytics; Ranitidine; Zollinger-Elli	1983
Failure of histamine H2-receptor antagonist therapy in Zollinger-Ellison syndrome. American journal of surgery, 1983, Volume: 145, Issue:1 Topics: Adult; Aged; Cimetidine; Female; Furans; Gastric Acidity Determination; Histamine H2 Antagonists; Hu	1983
[Duodenal ulcer and hypergastrinemia; differential diagnosis and possibilities of surgical treatment]. Nederlands tijdschrift voor geneeskunde, 1983, Jan-15, Volume: 127, Issue:3 Topics: Adult; Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Female; Gastrectomy; Gastrins; Humans; M	1983
Ranitidine--pharmacology and clinical use. Journal of clinical and hospital pharmacy, 1983, Volume: 8, Issue:1 Topics: Animals; Anti-Ulcer Agents; Chemical Phenomena; Chemistry; Cimetidine; Duodenal Ulcer; Furans; Gastr	1983
Changing concepts in the presentation, diagnosis and management of the Zollinger-Ellison syndrome. The Quarterly journal of medicine, 1983,Spring, Volume: 52, Issue:206 Topics: Adolescent; Adult; Angiography; Cimetidine; Female; Gastrectomy; Gastric Acid; Humans; Male; Middle	1983
Omeprazole in Zollinger-Ellison syndrome. Effects of a single dose and of long-term treatment in patients resistant to histamine H2-receptor antagonists. The New England journal of medicine, 1984, Mar-22, Volume: 310, Issue:12 Topics: Adult; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Drug Evaluation; Drug Resistance; Gastric Acid	1984
Anti-ulcer drugs and hypergastrinism: utilization in surgery. International journal of tissue reactions, 1984, Volume: 6, Issue:2 Topics: Cimetidine; Female; Gastrins; Histamine H2 Antagonists; Humans; Middle Aged; Ranitidine; Zollinger-E	1984
Removal of gastrinomas for control of Zollinger-Ellison syndrome. Annals of surgery, 1984, Volume: 200, Issue:4 Topics: Adult; Angiography; Cimetidine; Duodenum; Endoscopy; Female; Gastric Acid; Gastrins; Humans; Liver;	1984
[The role of H2 antagonists in Zollinger-Ellison syndrome]. La Clinica terapeutica, 1984, Dec-15, Volume: 111, Issue:5 Topics: Cimetidine; Histamine H2 Antagonists; Humans; Metiamide; Ranitidine; Zollinger-Ellison Syndrome	1984
[Zollinger-Ellison syndrome. Therapeutic aspects]. Annales de medecine interne, 1984, Volume: 135, Issue:5 Topics: Cimetidine; Gastrectomy; Humans; Streptozocin; Zollinger-Ellison Syndrome	1984
Management of Zollinger-Ellison syndrome. The New England journal of medicine, 1980, Oct-16, Volume: 303, Issue:16 Topics: Cimetidine; Furans; Gastrectomy; Humans; Ranitidine; Zollinger-Ellison Syndrome	1980
Cimetidine-induced erythema annulare centrifugum: no cross-sensitivity with ranitidine. British medical journal (Clinical research ed.), 1981, Sep-12, Volume: 283, Issue:6293 Topics: Aged; Cimetidine; Cross Reactions; Drug Eruptions; Erythema Multiforme; Female; Furans; Guanidines;	1981
Ranitidine reverses cimetidine-induced mental confusion in a patient with Zollinger-Ellison syndrome. Archives of surgery (Chicago, Ill. : 1960), 1983, Volume: 118, Issue:2 Topics: Cimetidine; Cognition Disorders; Confusion; Female; Furans; Guanidines; Humans; Middle Aged; Ranitid	1983
Cimetidine-resistant Zollinger-Ellison syndrome: successful management with ranitidine. Canadian Medical Association journal, 1983, Aug-01, Volume: 129, Issue:3 Topics: Adult; Anti-Ulcer Agents; Cimetidine; Furans; Humans; Male; Ranitidine; Zollinger-Ellison Syndrome	1983
Evaluation of antisecretory drug therapy of Zollinger-Ellison syndrome (ZES) using 24-hour pH monitoring. Digestive diseases and sciences, 1983, Volume: 28, Issue:7 Topics: Adult; Aged; Cimetidine; Drug Evaluation; Female; Furans; Gastric Acid; Gastric Acidity Determinatio	1983
Ranitidine or cimetidine. Annals of internal medicine, 1983, Volume: 99, Issue:4 Topics: Cimetidine; Duodenal Ulcer; Humans; Ranitidine; Zollinger-Ellison Syndrome	1983
Comparison of ranitidine and cimetidine in the treatment of gastric hypersecretion. Annals of internal medicine, 1984, Volume: 100, Issue:1 Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cimetidine; Dose-Response Relationsh	1984
[Ranitidine and cimetidine in Zollinger-Ellison syndrome]. Medicina clinica, 1983, Dec-17, Volume: 81, Issue:20 Topics: Adult; Cimetidine; Humans; Male; Ranitidine; Zollinger-Ellison Syndrome	1983
Cimetidine versus ranitidine for refractory Zollinger-Ellison syndrome. Canadian Medical Association journal, 1984, Mar-01, Volume: 130, Issue:5 Topics: Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Humans; Pirenzepine; Ranitidine; Zollinger	1984
Zollinger-Ellison syndrome, prolonged cimetidine administration and nasopharyngeal carcinoma:--a coincidence? International journal of tissue reactions, 1983, Volume: 5, Issue:4 Topics: Cimetidine; Herpesvirus 4, Human; Humans; Lymphocytes; Male; Middle Aged; Nasopharyngeal Neoplasms;	1983
[Description of a case of Zollinger-Ellison syndrome]. Minerva medica, 1984, May-07, Volume: 75, Issue:19 Topics: Benzodiazepinones; Body Weight; Cimetidine; Diarrhea; Female; Gastrectomy; Gastric Acid; Humans; Mid	1984
[Computer tomography in juvenile malignant gastrinoma]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1983, Volume: 139, Issue:2 Topics: Child; Cimetidine; Hepatectomy; Humans; Liver Neoplasms; Lymph Node Excision; Male; Tomography, X-Ra	1983
Evaluation of cimetidine usage in a community teaching hospital. QRB. Quality review bulletin, 1983, Volume: 9, Issue:8 Topics: Cimetidine; Drug Utilization; Duodenal Ulcer; Esophageal Neoplasms; Hospitals, Community; Hospitals,	1983
The effect of cimetidine on pepsin secretion in patients with Zollinger Ellison syndrome. Journal of the Royal Naval Medical Service, 1983,Winter, Volume: 69, Issue:3 Topics: Adult; Cimetidine; Female; Gastric Acid; Humans; Middle Aged; Pepsin A; Zollinger-Ellison Syndrome	1983
Cimetidine treatment for Zollinger-Ellison syndrome. A case report. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1984, Volume: 3, Issue:2 Topics: Adult; Cimetidine; Combined Modality Therapy; Gastric Acid; Humans; Male; Zollinger-Ellison Syndrome	1984
Radiographic response to cimetidine in patients with basal gastric acid hypersecretion. AJR. American journal of roentgenology, 1984, Volume: 142, Issue:1 Topics: Adolescent; Adult; Cimetidine; Digestive System; Duodenal Ulcer; Female; Gastric Acid; Gastrins; Hum	1984
Failure of cimetidine in Zollinger-Ellison syndrome. Digestive diseases and sciences, 1983, Volume: 28, Issue:11 Topics: Administration, Oral; Biological Availability; Cimetidine; Dose-Response Relationship, Drug; Female;	1983
Peptic ulcer disease. The Journal of family practice, 1984, Volume: 18, Issue:3 Topics: Adult; Antacids; Child; Cimetidine; Female; Humans; Male; Peptic Ulcer; Stress, Physiological; Zolli	1984
Basis for failure of cimetidine in patients with Zollinger-Ellison syndrome. Digestive diseases and sciences, 1984, Volume: 29, Issue:4 Topics: Biological Availability; Cimetidine; Gastric Acid; Humans; Zollinger-Ellison Syndrome	1984
Secretin-induced gastrin response in the Zollinger-Ellison syndrome and chronic duodenal ulcer patients before and after cimetidine treatment. The American journal of gastroenterology, 1984, Volume: 79, Issue:5 Topics: Adolescent; Adult; Chronic Disease; Cimetidine; Duodenal Ulcer; Female; Gastrins; Humans; Male; Midd	1984
Conservative surgery in the Zollinger-Ellison syndrome. The British journal of surgery, 1984, Volume: 71, Issue:6 Topics: Adult; Cimetidine; Follow-Up Studies; Gastric Acid; Humans; Male; Middle Aged; Pylorus; Vagotomy; Zo	1984
Thyrotropin-releasing hormone suppressed gastric acid output in patients with Zollinger-Ellison syndrome and systemic mastocytosis. The American journal of medicine, 1981, Volume: 71, Issue:6 Topics: Cimetidine; Gastric Acid; Gastric Mucosa; Humans; Thyrotropin-Releasing Hormone; Urticaria Pigmentos	1981
[The present state of knowledge on the treatment of peptic diseases with cimetidine]. Der Internist, 1981, Volume: 22, Issue:12 Topics: Cimetidine; Double-Blind Method; Duodenal Ulcer; Esophagitis, Peptic; Gastric Acid; Guanidines; Half	1981
Gastric acid regulates the release of plasma secretin in man. European journal of clinical investigation, 1982, Volume: 12, Issue:4 Topics: Adult; Cimetidine; Duodenal Ulcer; Fasting; Food; Gastric Acid; Humans; Hydrogen-Ion Concentration;	1982
Nutrient malabsorption in the Zollinger-Ellison syndrome. Normalization during long-term cimetidine therapy. Archives of internal medicine, 1983, Volume: 143, Issue:2 Topics: Cimetidine; Gastrectomy; Gastric Acid; Guanidines; Humans; Malabsorption Syndromes; Male; Middle Age	1983
Cimetidine-induced impotence and breast changes in patients with gastric hypersecretory states. The New England journal of medicine, 1983, Apr-14, Volume: 308, Issue:15 Topics: Adult; Breast; Cimetidine; Erectile Dysfunction; Gastric Acid; Guanidines; Gynecomastia; Humans; Mal	1983
Medical and surgical options in the management of patients with gastrinoma. Gastroenterology, 1983, Volume: 84, Issue:6 Topics: Cimetidine; Gastrectomy; Gastric Acid; Humans; Zollinger-Ellison Syndrome	1983
Of gastrinomas and their management. Gastroenterology, 1983, Volume: 84, Issue:6 Topics: Cimetidine; Gastrectomy; Humans; Zollinger-Ellison Syndrome	1983
The role of surgery in the Zollinger-Ellison syndrome. Annals of surgery, 1983, Volume: 197, Issue:5 Topics: Adolescent; Adult; Aged; Cimetidine; Female; Gastrectomy; Gastric Acidity Determination; Gastrins; H	1983
Cimetidine in the treatment of Zollinger-Ellison syndrome. American journal of surgery, 1983, Volume: 146, Issue:1 Topics: Adolescent; Adult; Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Zollinger-Elliso	1983
[Zollinger-Ellison syndrome]. Chirurgia italiana, 1982, Volume: 34, Issue:5 Topics: Cimetidine; Gastric Juice; Gastric Mucosa; Gastrins; Gastroscopy; Humans; Peptic Ulcer; Zollinger-El	1982
Cimetidine: clinical uses and possible side effects. Postgraduate medicine, 1980, Volume: 68, Issue:6 Topics: Cimetidine; Confusion; Esophagitis, Peptic; Gastrointestinal Hemorrhage; Guanidines; Humans; Male; N	1980
[Indications for cimetidine]. Revista espanola de las enfermedades del aparato digestivo, 1981, Volume: 59, Issue:3 Topics: Cimetidine; Duodenal Ulcer; Gastroesophageal Reflux; Gastrointestinal Hemorrhage; Guanidines; Humans	1981
Hypergastrinemia and Zollinger-Ellison syndrome. The Journal of the Kansas Medical Society, 1982, Volume: 83, Issue:1 Topics: Cimetidine; Gastrins; Humans; Zollinger-Ellison Syndrome	1982
Diagnosis and management of gastrinoma (Zollinger-Ellison Syndrome) Mayo Clinic proceedings, 1982, Volume: 57, Issue:4 Topics: Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Gastric Acidity Determination; Gastrins; Humans	1982
Zollinger-Ellison syndrome: diagnosis and treatment. Missouri medicine, 1982, Volume: 79, Issue:3 Topics: Cimetidine; Gastrins; Humans; Zollinger-Ellison Syndrome	1982
[Changes in the diagnosis and treatment of Zollinger-Ellison syndrome (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1982, May-07, Volume: 107, Issue:18 Topics: Adult; Aged; Calcium; Cimetidine; Female; Gastric Acidity Determination; Gastrins; Humans; Male; Mid	1982
[Zollinger-Ellison syndrome--changes in surgical therapy. Analysis of 27 patients]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1982, Volume: 53, Issue:4 Topics: Adult; Aged; Cimetidine; Female; Gastrectomy; Gastrins; Histamine H2 Antagonists; Humans; Male; Midd	1982
Uses and abuses of cimetidine. Journal of the Iowa Medical Society, 1982, Volume: 72, Issue:4 Topics: Cimetidine; Duodenal Ulcer; Guanidines; Humans; Zollinger-Ellison Syndrome	1982
The role of surgery in patients with Zollinger-Ellison syndrome (ZES) managed medically. Annals of surgery, 1982, Volume: 196, Issue:3 Topics: Adult; Aged; Cimetidine; Female; Gastrectomy; Guanidines; Humans; Male; Middle Aged; Neoplasm Metast	1982
The role of surgery in children with the Zollinger-Ellison syndrome. Surgery, 1982, Volume: 92, Issue:4 Topics: Adolescent; Age Factors; Child; Child, Preschool; Cimetidine; Female; Follow-Up Studies; Gastrectomy	1982
Prolonged secretory inhibition during cimetidine treatment in Zollinger-Ellison patients. Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:3 Topics: Adult; Aged; Cimetidine; Female; Gastric Acid; Guanidines; Humans; Male; Middle Aged; Zollinger-Elli	1982
Zollinger-Ellison Syndrome. Journal of the Medical Association of the State of Alabama, 1982, Volume: 52, Issue:4 Topics: Calcium; Cimetidine; Diagnosis, Differential; Female; Gastrins; Humans; Male; Middle Aged; Zollinger	1982
[Current therapeutic problems in the Zollinger-Ellison syndrome. Personal cases]. Minerva medica, 1982, Nov-10, Volume: 73, Issue:43 Topics: Adult; Cimetidine; Female; Gastrectomy; Gastrins; Guanidines; Humans; Middle Aged; Zollinger-Ellison	1982
[Diagnosis of Zollinger-Ellison syndrome (ZES). Responsibility of the clinician]. Revue medicale de la Suisse romande, 1982, Volume: 102, Issue:9 Topics: Adult; Cimetidine; Gastrectomy; Gastric Acid; Gastrins; Humans; Male; Middle Aged; Zollinger-Ellison	1982
An aggressive approach to the medical management of peptic ulcer disease. Archives of internal medicine, 1981, Volume: 141, Issue:7 Topics: Acute Disease; Antacids; Cimetidine; Duodenal Ulcer; Endoscopy; Fiber Optic Technology; Humans; Pept	1981
[Cimetidine and primary hyperparathyroidism: failure of reduction of blood levels of parathyroid hormone in 5 cases of primary hyperparathyroidism]. La Clinica terapeutica, 1981, Jul-15, Volume: 98, Issue:1 Topics: Adult; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism; Male; Middle Aged; Parathyroid H	1981
Repeated vomiting of gastric juice in a patient with Zollinger-Ellison syndrome. Modifying influence upon clinical features. Digestive diseases and sciences, 1981, Volume: 26, Issue:8 Topics: Cimetidine; Duodenal Neoplasms; Female; Gastric Juice; Humans; Middle Aged; Paraneoplastic Endocrine	1981
Gastrinoma--current observations and management options. Journal of the Medical Association of the State of Alabama, 1981, Volume: 51, Issue:6 Topics: Adult; Cimetidine; Female; Gastrins; Humans; Male; Middle Aged; Zollinger-Ellison Syndrome	1981
Stomal and recurrent ulceration: medical or surgical management? American journal of surgery, 1980, Volume: 139, Issue:1 Topics: Cimetidine; Gastrectomy; Guanidines; Humans; Peptic Ulcer; Postoperative Complications; Recurrence;	1980
Interest of a combined antisecretory treatment, cimetidine and pirenzepin, in the management of severe forms of Zollinger-Ellison syndrome. Digestion, 1980, Volume: 20, Issue:1 Topics: Adult; Aged; Benzodiazepinones; Cimetidine; Female; Gastric Juice; Guanidines; Humans; Male; Middle	1980
The declining role of the surgeon in the treatment of acid-peptic diseases. Archives of surgery (Chicago, Ill. : 1960), 1980, Volume: 115, Issue:2 Topics: Anti-Ulcer Agents; Cimetidine; Guanidines; Humans; Peptic Ulcer; United States; Zollinger-Ellison Sy	1980
Vagotomy in Z-E syndrome. Gastroenterology, 1980, Volume: 78, Issue:5 Pt 1 Topics: Cimetidine; Gastric Juice; Humans; Vagotomy; Zollinger-Ellison Syndrome	1980
Cimetidine: appropriate uses in 1980. Texas medicine, 1980, Volume: 76, Issue:5 Topics: Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Guanidines; Humans; Recurrence; Stomach Ulcer; Zoll	1980
Zollinger-Ellison syndrome in a child: medical treatment with cimetidine. Archives of disease in childhood, 1980, Volume: 55, Issue:3 Topics: Child; Cimetidine; Guanidines; Humans; Liver; Male; Zollinger-Ellison Syndrome	1980
Cimetidine: chronicle of a new drug. Delaware medical journal, 1980, Volume: 52, Issue:11 Topics: Cimetidine; Guanidines; Humans; Peptic Ulcer; Stomach Diseases; Zollinger-Ellison Syndrome	1980
Management and long-term results in patients with two-thirds gastrectomy and stomal ulcer. American journal of surgery, 1981, Volume: 141, Issue:1 Topics: Antacids; Bombesin; Calcium; Cimetidine; Female; Gastrectomy; Gastric Acid; Gastrins; Humans; Male;	1981
[Possibilities of the use of present-day antisecretory preparation omeprazole]. Klinicheskaia meditsina, 1994, Volume: 72, Issue:6 Topics: Adult; Aged; Aluminum Hydroxide; Antacids; Benzilates; Benzocaine; Choline; Cimetidine; Drug Combina	1994
[Zollinger-Ellison syndrome]. Klinicheskaia meditsina, 1994, Volume: 72, Issue:3 Topics: Adult; Cimetidine; Combined Modality Therapy; Diagnosis, Differential; Female; Gastrectomy; Humans;	1994
Parenteral control of gastric acid hypersecretion in patients with Zollinger-Ellison syndrome. Digestive diseases and sciences, 1993, Volume: 38, Issue:10 Topics: Administration, Oral; Cimetidine; Dose-Response Relationship, Drug; Famotidine; Female; Gastric Acid	1993
[Treatment of peptic ulcer in the Zollinger-Ellison syndrome with histamine H2-receptor antagonists (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1977, Nov-25, Volume: 102, Issue:47 Topics: Adult; Cimetidine; Female; Gastrins; Hepatitis B; Histamine H2 Antagonists; Humans; Male; Metiamide;	1977
[Efficacy of combined anti-secretory treatment (cimétidine and pirenzepin) in Zollinger-Ellison syndrome]. La Nouvelle presse medicale, 1977, Nov-12, Volume: 6, Issue:38 Topics: Adult; Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Gastric Juice; Guanidines; Histamin	1977
[Histamine H-2 receptor antagonists and medical treatment of Zollinger-Ellison syndrome]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1978, Volume: 54, Issue:5-8 Topics: Administration, Oral; Adult; Cimetidine; Female; Guanidines; Histamine H2 Antagonists; Humans; Male;	1978
[Discussions with the speakers on histamine-H2-receptor antagonists. 21 April 1978, Vienna]. Acta medica Austriaca. Supplement, 1978, Volume: 10 Topics: Acetylcholine; Cimetidine; Gastric Juice; Gastrins; Guanidines; Histamine; Histamine H2 Antagonists;	1978
[Histamine H2 receptor antagonists. Pharmacology and clinical applications]. La Revue du praticien, 1978, Nov-21, Volume: 28, Issue:53 Topics: Animals; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Gastric Juice; Gastric Mucosa; Gastritis;	1978
[A case of Zollinger-Ellison syndrome associated with multiple endocrine adenomatosis (Type I)--special reference to treatment of Zollinger-Ellison syndrome with cimetidine (author's transl)]. Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1979, Volume: 76, Issue:6 Topics: Cimetidine; Female; Guanidines; Humans; Middle Aged; Multiple Endocrine Neoplasia; Zollinger-Ellison	1979
Cimetidine, pH, and Zollinger-Ellison syndrome. Lancet (London, England), 1977, Nov-26, Volume: 2, Issue:8048 Topics: Cimetidine; Follow-Up Studies; Gastric Acidity Determination; Guanidines; Humans; Hydrogen-Ion Conce	1977
Serum-prolactin in patients receiving chronic oral cimetidine. Lancet (London, England), 1978, Apr-22, Volume: 1, Issue:8069 Topics: Administration, Oral; Cimetidine; Female; Guanidines; Humans; Male; Prolactin; Zollinger-Ellison Syn	1978
Plasma-secretin in management of cimetidine therapy for Zollinger-Ellison syndrome. Lancet (London, England), 1978, Jul-08, Volume: 2, Issue:8080 Topics: Administration, Oral; Cimetidine; Depression, Chemical; Duodenum; Gastric Acidity Determination; Gas	1978
Cimetidine. JPMA. The Journal of the Pakistan Medical Association, 1979, Volume: 29, Issue:7 Topics: Cimetidine; Duodenal Ulcer; Guanidines; Humans; Zollinger-Ellison Syndrome	1979
The Zollinger-Ellison syndrome: a new approach. Clinical bulletin, 1979, Volume: 9, Issue:4 Topics: Cimetidine; Drug Therapy, Combination; Fluorouracil; Humans; Laparoscopy; Male; Middle Aged; Radiogr	1979
Cimetidine in the USA. Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 55 Topics: Cimetidine; Drug Evaluation; Duodenal Ulcer; Guanidines; Humans; Pancreatic Diseases; United States;	1979
[Cimetidine. Its role in digestive diseases. Current status of our knowledge]. Revue medicale de Liege, 1979, Jan-01, Volume: 34, Issue:1 Topics: Cimetidine; Duodenal Ulcer; Gastrointestinal Hemorrhage; Guanidines; Humans; Peptic Ulcer; Stomach U	1979
[New perspectives in the treatment of Zollinger-Ellison syndrome. Effect of cimetidine]. Ugeskrift for laeger, 1977, Aug-29, Volume: 139, Issue:35 Topics: Adult; Aged; Cimetidine; Drug Evaluation; Female; Gastric Juice; Gastrins; Guanidines; Humans; Male;	1977
Cimetidine or surgery for the Zollinger-Ellison syndrome? Gastroenterology, 1978, Volume: 75, Issue:1 Topics: Cimetidine; Gastrectomy; Humans; Zollinger-Ellison Syndrome	1978
Zollinger-Ellison syndrome with pneumopericardium. Digestive diseases and sciences, 1979, Volume: 24, Issue:6 Topics: Biopsy; Cimetidine; Gastrectomy; Gastric Mucosa; Humans; Male; Middle Aged; Pneumopericardium; Radio	1979
Effect of vagotomy in Zollinger-Ellison syndrome. Gastroenterology, 1979, Volume: 77, Issue:4 Pt 1 Topics: Adult; Cimetidine; Gastric Juice; Gastrins; Humans; Male; Middle Aged; Vagotomy; Zollinger-Ellison S	1979
Zollinger-Ellison syndrome unresponsive to cimetidine. The American journal of gastroenterology, 1979, Volume: 72, Issue:2 Topics: Administration, Oral; Adult; Atropine; Cimetidine; Gastric Juice; Guanidines; Humans; Infusions, Par	1979
Long-term cimetidine and anticholinergic therapy in patients with gastrinoma. American journal of surgery, 1979, Volume: 138, Issue:3 Topics: Administration, Oral; Adult; Antacids; Cimetidine; Drug Evaluation; Female; Gastric Juice; Gastrins;	1979
[Prolonged treatment of Zollinger-Ellison by cimetidine (author's transl)]. La Nouvelle presse medicale, 1979, Apr-14, Volume: 8, Issue:17 Topics: Cimetidine; Follow-Up Studies; Gastrectomy; Guanidines; Humans; Zollinger-Ellison Syndrome	1979
Cimetidine treatment of acute and chronic Zollinger-Ellison syndrome. World journal of surgery, 1979, Sep-20, Volume: 3, Issue:5 Topics: Acute Disease; Benzodiazepines; Chronic Disease; Cimetidine; Duodenal Neoplasms; Gastrectomy; Gastri	1979
A review of the Zollinger-Ellison syndrome--with particular reference to a patient treated with cimetidine. Postgraduate medical journal, 1979, Volume: 55, Issue:648 Topics: Aged; Cimetidine; Guanidines; Humans; Male; Pancreatic Ducts; Radiography; Zollinger-Ellison Syndrom	1979
Cimetidine in the management of the Zollinger-Ellison syndrome. Postgraduate medical journal, 1977, Volume: 53, Issue:626 Topics: Aged; Cimetidine; Guanidines; Humans; Male; Zollinger-Ellison Syndrome	1977
[Treatment of patients with Zollinger-Ellison syndrome with histamine H2 receptor antagonists]. Tijdschrift voor gastro-enterologie, 1977, Volume: 20, Issue:6 Topics: Adult; Cimetidine; Female; Gastric Juice; Gastrins; Guanidines; Humans; Male; Metiamide; Thiourea; Z	1977
Symposium on peptic ulcer disease: 4. Panel discussion on peptic ulcer disease. Canadian journal of surgery. Journal canadien de chirurgie, 1978, Volume: 21, Issue:1 Topics: Cimetidine; Duodenal Ulcer; Gastrectomy; Gastric Juice; Humans; Male; Peptic Ulcer; Vagotomy; Zollin	1978
Report on the United States experience with cimetidine in Zollinger-Ellision syndrome and other hypersecretory states. Gastroenterology, 1978, Volume: 74, Issue:2 Pt 2 Topics: Adult; Aged; Antacids; Cimetidine; Female; Gastric Juice; Guanidines; Gynecomastia; Histamine; Human	1978
[Zollinger-Ellison syndrome: total gastrectomy or longtime cimetidine therapy?]. Deutsche medizinische Wochenschrift (1946), 1978, Feb-24, Volume: 103, Issue:8 Topics: Cimetidine; Humans; Zollinger-Ellison Syndrome	1978
[Zolliner-Ellison syndrome: total gastrectomy or longtime therapy using cimetidine?]. Deutsche medizinische Wochenschrift (1946), 1978, Jul-21, Volume: 103, Issue:29 Topics: Cimetidine; Gastrectomy; Humans; Zollinger-Ellison Syndrome	1978
Sense with cimetidine. JAMA, 1978, Aug-11, Volume: 240, Issue:6 Topics: Cimetidine; Gastric Juice; Guanidines; Humans; Peptic Ulcer; Secretory Rate; Zollinger-Ellison Syndr	1978
[Prolonged treatment with cimetidine in 2 cases of Zollinger-Ellison syndrome]. La Nouvelle presse medicale, 1978, May-27, Volume: 7, Issue:21 Topics: Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Time Factors; Zollinger-Ellison Syndrome	1978
The Zollinger-Ellison syndrome--23 years later. Annals of surgery, 1978, Volume: 188, Issue:3 Topics: Adolescent; Adult; Aged; Calcium; Cimetidine; Female; Follow-Up Studies; Gastrectomy; Gastric Acidit	1978
[Treatment of Zollinger Ellison's syndrome with cimetidine (author's transl)]. Revista medica de Chile, 1978, Volume: 106, Issue:6 Topics: Adult; Cimetidine; Female; Gastrectomy; Gastric Juice; Gastrins; Guanidines; Humans; Peptic Ulcer; R	1978
Cimetidine treatment in Zollinger-Ellison syndrome. Advances in experimental medicine and biology, 1978, Volume: 106 Topics: Cimetidine; Guanidines; Humans; Zollinger-Ellison Syndrome	1978
Long-term treatment with histamine H2-receptor antagonists in Zollinger-Ellison syndrome. The American journal of gastroenterology, 1978, Volume: 70, Issue:3 Topics: Adult; Cimetidine; Depression, Chemical; Drug Evaluation; Female; Gastric Juice; Gastric Mucosa; Gua	1978
[Dysgastrinemia and the ulcer syndrome]. Acta gastroenterologica Latinoamericana, 1978, Volume: 8, Issue:2 Topics: Animals; Cimetidine; Dogs; Duodenal Ulcer; Gastrins; Histamine H2 Antagonists; Humans; Zollinger-Ell	1978
Therapeutic uses of cimetidine. Scottish medical journal, 1977, Volume: 22, Issue:4 Topics: Acute Disease; Chronic Disease; Cimetidine; Drug Evaluation; Gastritis; Guanidines; Humans; Peptic U	1977
Zollinger-Ellison syndrome: provocative diagnostic tests. Annals of internal medicine, 1977, Volume: 87, Issue:6 Topics: Calcium; Cimetidine; Food; Gastrins; Gluconates; Humans; Secretin; Zollinger-Ellison Syndrome	1977
Comparative tolerability profile of omeprazole in clinical trials. Digestive diseases and sciences, 1991, Volume: 36, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransferases; Cimet	1991
Control of metastatic Zollinger-Ellison syndrome with high-dose H2-receptor antagonists. The British journal of clinical practice, 1990, Volume: 44, Issue:12 Topics: Adult; Cimetidine; Gastrinoma; Humans; Liver Neoplasms; Male; Ranitidine; Zollinger-Ellison Syndrome	1990
Development of gastric argyrophil carcinoid tumors in a case of Zollinger-Ellison syndrome with primary hyperparathyroidism during long-term antisecretory treatment. Cancer, 1987, Jun-01, Volume: 59, Issue:11 Topics: Carcinoid Tumor; Cell Division; Cimetidine; Female; Gastrectomy; Humans; Hyperparathyroidism; Middle	1987
Parenteral antisecretory drug therapy in patients with Zollinger-Ellison syndrome. Gastroenterology, 1989, Volume: 96, Issue:6 Topics: Administration, Oral; Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Cimetidine; Do	1989
Effects of omeprazole on acid secretion and acid-related symptoms in patients with Zollinger-Ellison syndrome. Scandinavian journal of gastroenterology. Supplement, 1989, Volume: 166 Topics: Adult; Aged; Cimetidine; Female; Gastric Acid; Gastrins; Humans; Long-Term Care; Male; Middle Aged;	1989
[The treatment of Zollinger-Ellison syndrome]. Zentralblatt fur Chirurgie, 1989, Volume: 114, Issue:9 Topics: Anastomosis, Roux-en-Y; Cimetidine; Combined Modality Therapy; Gastrectomy; Gastric Acidity Determin	1989
A model study of the regulation of gastric acid secretion. The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1 Topics: Achlorhydria; Cimetidine; Computer Simulation; Duodenal Ulcer; Food; Gastric Acid; Gastric Emptying;	1989
Famotidine, a new, potent, long-acting histamine H2-receptor antagonist: comparison with cimetidine and ranitidine in the treatment of Zollinger-Ellison syndrome. Gastroenterology, 1985, Volume: 88, Issue:4 Topics: Aged; Cimetidine; Delayed-Action Preparations; Famotidine; Histamine H2 Antagonists; Humans; Middle	1985
Treatment of Zollinger-Ellison syndrome with exploratory laparotomy, proximal gastric vagotomy, and H2-receptor antagonists. A prospective study. Gastroenterology, 1985, Volume: 89, Issue:2 Topics: Adolescent; Adult; Child; Cimetidine; Combined Modality Therapy; Endoscopy; Female; Gastric Acid; Ga	1985
Effectiveness of omeprazole in seven patients with Zollinger-Ellison syndrome resistant to histamine H2-receptor antagonists. Digestive diseases and sciences, 1986, Volume: 31, Issue:7 Topics: Adult; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Cimetidine; Drug Resistance; Drug Thera	1986
[Cimetidine, ranitidine and somatostatin in the medical treatment of acute and chronic Zollinger-Ellison syndrome]. Revista espanola de las enfermedades del aparato digestivo, 1987, Volume: 72, Issue:6 Topics: Acute Disease; Adult; Chronic Disease; Cimetidine; Humans; Male; Ranitidine; Somatostatin; Zollinger	1987
The progressive Zollinger-Ellison syndrome in multiple endocrine neoplasia. Surgery, gynecology & obstetrics, 1988, Volume: 167, Issue:5 Topics: Adult; Apudoma; Cimetidine; Follow-Up Studies; Gastrectomy; Gastrinoma; Humans; Male; Middle Aged; M	1988
Aggressive resection of metastatic disease in selected patients with malignant gastrinoma. Annals of surgery, 1986, Volume: 203, Issue:4 Topics: Abdominal Neoplasms; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Combin	1986
[Cimetidine or ranitidine?]. Nederlands tijdschrift voor geneeskunde, 1986, Apr-19, Volume: 130, Issue:16 Topics: Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Esophagitis, Peptic; Gynecomastia; Humans; Male; Pep	1986
Cimetidine pharmacokinetics in patients with Zollinger-Ellison syndrome. Gastroenterology, 1987, Volume: 93, Issue:1 Topics: Adult; Aged; Cimetidine; Drug Resistance; Female; Gastric Acid; Half-Life; Humans; Intestinal Absorp	1987
Gastrinoma. The Surgical clinics of North America, 1986, Volume: 66, Issue:4 Topics: Cimetidine; Diagnosis, Differential; Female; Gastrectomy; Gastric Juice; Gastrins; Male; Methods; Ra	1986
The nature of gastric secretions in a patient with Zollinger-Ellison syndrome without peptic ulceration. Clinica chimica acta; international journal of clinical chemistry, 1986, Aug-30, Volume: 159, Issue:1 Topics: Adult; Carbohydrates; Cimetidine; Female; Gastric Juice; Humans; Zollinger-Ellison Syndrome	1986
The Zollinger-Ellison syndrome: a review of the St Vincent's Hospital, Melbourne experience. The Australian and New Zealand journal of surgery, 1985, Volume: 55, Issue:5 Topics: Adult; Aged; Cimetidine; Duodenal Ulcer; Esophagitis, Peptic; Female; Gastric Acid; Humans; Hypercal	1985
The Zollinger-Ellison syndrome. A case report. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Oct-12, Volume: 68, Issue:8 Topics: Adolescent; Cimetidine; Duodenal Ulcer; Gastrointestinal Hemorrhage; Humans; Male; Zollinger-Ellison	1985
Central nervous system toxicity associated with concurrent use of triazolam and cimetidine. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:9 Topics: Central Nervous System Diseases; Cimetidine; Drug Interactions; Female; Humans; Middle Aged; Triazol	1985
Development of cimetidine resistance in the Zollinger-Ellison syndrome. Gut, 1985, Volume: 26, Issue:11 Topics: Adult; Cimetidine; Drug Resistance; Female; Gastric Acid; Gastrins; Humans; Time Factors; Zollinger-	1985

cimetidine and Zollinger-Ellison Syndrome

Research Excerpts

Research

Studies (187)

Authors

Clinical Trials (2)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Hotz, J	2
Mignon, M	16
Vallot, T	4
Mayeur, S	2
Bonfils, S	16
Treffot, MJ	1
McCarthy, DM	8
Hyman, PE	1
Raufman, JP	4
Collins, SM	1
Pandol, SJ	2
Korman, LY	1
Collen, MJ	5
Cornelius, MJ	3
Feld, MK	1
Gardner, JD	13
Jensen, RT	16
Malagelada, JR	4
Stabile, BE	2
Ippoliti, AF	2
Walsh, JH	2
Passaro, E	3
Bollen, EC	1
van Knippenberg, LA	1
Dawson, J	1
Richards, DA	1
Stables, R	1
Dixon, GT	1
Cockel, R	1
Mee, AS	2
Ismail, S	1
Bornman, PC	2
Marks, IN	2
Lambers, CB	1
Lind, T	1
Moberg, S	1
Jansen, JB	2
Olbe, L	1
Carella, G	1
Cavina, E	2
Seccia, M	1
Pagliai, E	1
Rosso, R	1
Paganelli, M	1
Evangelista, G	1
Harmon, JW	1
Norton, JA	5
Collin, MJ	1
Krudy, AG	1
Shawker, TH	1
Doppman, JL	3
d'Avis, J	1
McArthur, KE	4
Howard, JM	5
Maton, PN	8
Cherner, JA	2
Sitges Serra, A	1
Dammann, HG	1
Walter, TA	1
Müller, P	1
Simon, B	1
Pounder, RE	1
Ribera Pascuet, E	1
González Atienza, J	1
Obiols Alfonso, G	1
Mesa Manteca, J	1
René, E	1
Rigaud, D	2
Landor, JH	1
Merrett, AC	1
Marks, R	1
Dudley, FJ	1
Pedrazzoli, S	1
Petrin, P	1
Pasquali, C	1
Militello, C	1
Sperti, C	1
Fregonese, V	1
Simini, G	1
Habal, FM	1
Soldin, SJ	1
Greenberg, GR	2
Mazure, R	1
Strum, WB	1
Acero, D	1
Montgomery, H	1
Ciarleglio, CA	2
Ribera, E	1
González-Atienza, J	1
Krassowski, J	1
de Gara, CJ	1
Gledhill, T	2
Hunt, RH	2
Eshchar, J	1
Neuman, MG	1
Pavlotzky, M	1
Saibil, FG	1
Becker, HD	1
de la Pierre, M	1
Aricò, S	1
Capussotti, L	1
Dellepiane, M	1
Marucci, M	1
Gandini, G	1
Imarisio, P	1
Rödl, W	1
Nebel, G	1
Harms, D	1
Sommers, LS	1
Cunningham, E	1
Cohen, EM	1
Aron, JM	1
Colley, S	1
Billings, JA	1
Gray, SP	1
Friesen, SR	1
Santhi Swaroop, V	1
Shinde, SR	1
DeSouza, LJ	1
Antia, FP	1
Smith, HJ	1
Ziemniak, JA	2
Madura, M	1
Adamonis, AJ	1
Olinger, EJ	2
Dreyer, M	1
Schentag, JJ	1
Medley, ES	1
Quatrini, M	1
Basilisco, G	1
Conte, D	1
Bardella, MT	1
Bozzani, A	1
Bianchi, PA	1
Freston, JW	1
Hutton, SW	1
Morley, JE	1
Parent, MK	1
Johnson, GJ	1
Silvis, SE	1
Romankiewicz, JA	1
Reidenberg, MM	1
McCloy, RF	2
Baron, JH	1
Bryant, MG	1
Bloom, SR	1
King, CE	1
Toskes, PP	1
Allende, HD	1
Bissonnette, BM	1
Duncan, WC	1
Durgin, PL	1
Gillin, JC	1
Edis, AJ	1
Adson, MA	1
van Heerden, JA	1
Go, VL	1
Lamers, CB	7
Thompson, JC	2
Lewis, BG	1
Wiener, I	1
Townsend, CM	2
Deveney, CW	3
Stein, S	1
Way, LW	2
Guzzetti, A	1
Premoli, P	1
Babb, RR	1
Pérez Blanco, FJ	1
Salmerón Escobar, J	1
Castañeda Navarro, E	1
Peña Angulo, JF	1
Ryss, ES	1
Jedrzejewski, R	1
Festen, HP	4
van Tongeren, JH	4
Fleshler, B	2
Jenike, MA	1
Castro, Lde P	1
Salgado, JA	1
Brooks, CL	1
McPhee, MS	1
Clain, JE	1
Marshall, JB	1
Feurle, GE	3
Helmstädter, V	1
Hoevels, J	1
Wenzel-Herzer, G	1
Klempa, I	2
Encke, A	1
Classen, M	1
Phillips, TE	1
Schulze, K	1
Brennan, MF	1
Wesley, RA	2
Wilson, SD	1
Stage, JG	3
Stadil, F	4
Reddy, AB	1
Capitaine, Y	1
Rime, F	1
Achkar, E	1
Gasparoni, P	1
Rota, G	1
Fioretti, D	1
Lo Giudice, C	1
Manente, P	1
Valmachino, G	1
Conte, N	1
Bonnefond, A	2
Gratton, J	3
Perry, HA	1
Kennedy, T	1
Green, WE	1
Galmiche, JP	1
Dupas, JL	1
Penn, I	1
Friedman, CJ	1
Knudson, KB	1
Dyck, WP	2
Drake, DP	1
Maciver, AG	1
Atwell, JD	1
Kester, RR	1
Paulshock, BZ	1
Speranza, V	1
Basso, N	1
Lezoche, E	1
Materia, A	1
Bagarani, M	1
Paduos, A	1
Degtiareva, II	1
Semeunovich, S	1
Kharchenko, NV	1
Petrovich, S	1
Gaĭsenko, AV	1
Egorova, IT	1
Kreĭmer, LI	1
Krivosheev, AB	1
Khvan, LA	1
Vinayek, R	3
Hahne, WF	1
Euler, AR	1
Hausamen, TU	2
Fritsch, WP	3
Scholten, T	2
Jungblut, R	1
Strohmeyer, G	2
May, RJ	1
Long, BW	1
Danne, O	1
Maria, J	1
Cortot, A	2
Siepler, JK	1
Campagna, KD	1
Donahue, PE	1
Bombeck, CT	1
Kloeti, G	2
Gislon, J	1
Shiratori, K	1
Watanabe, S	1
Ohta, Y	1
Maruyama, M	1
Kozu, T	1
Kurokawa, K	1
Takeuchi, T	1
Kawai, F	1
Sasaki, K	1
Mori, M	1
Uegaki, K	1
Hoffenberg, P	1
Müller, JE	1
Hengels, KJ	1
Modlin, IM	1
Spiegel, AM	1
Lopatin, R	1
Peikin, S	1
McCarthy, D	1
Straus, E	1
Greenstein, RJ	1
Yalow, RS	1
Voget, E	1
Schollmeyer, P	1
Maltz, C	1
Lightdale, CJ	1
Ruyters, L	1
Sharpe, PC	1
Malmstrom, J	1
Malchow, H	1
Sewing, KF	1
Brogden, RN	1
Heel, RC	1
Speight, TM	1
Avery, GS	1
Lamersen, CB	1
Delchier, JC	3
Soule, JC	3
Bader, JP	3
Finkelstein, W	1
Isselbacher, KJ	1
Fiddian-Green, RG	1
Green, JD	1
Sharma, SM	1
Pierozak, RF	1
Akgun, S	1
Richardson, CT	2
Feldman, M	2
McClelland, RN	2
Dickerman, RM	2
Kumpuris, D	1
Fordtran, JS	2
Groarke, JF	1
Haggstrom, GD	1
Halpern, NB	1
Hirschowitz, BI	1
Crane, SA	1
Summers, RW	1
Heeringa, WG	1
Wyke, RJ	1
Hill, GL	1
Axon, AT	1
Larkworthy, W	1
Davies, HL	1
Perey, BJ	1
Cohen, MM	1
Doris, PJ	1
Goligher, JC	1
Jeejeebhoy, KN	1
Weterman, IT	1
Castell, DO	1
Vitaux, J	1
Paolaggi, JA	1
Schlippert, W	1
Deveney, KS	1
Carvajal, C	1
Otaíza, E	1
Klinger, J	1
Brunner, H	1
Cosen, JN	1
Thomson, TJ	1
Pisegna, JR	1
Slimak, GG	1
Metz, DC	1
Simon, TJ	1
Bradstreet, DC	1
Kato, H	1
Shimozawa, E	1
Kojima, T	1
Tanabe, T	1
Johnston, SR	1
Wright, PL	1
Nechaĭ, AI	1
Kalinin, AP	1
Trofimov, VT	1
Howard, TJ	1
Lehy, T	1
Ruszniewski, P	1
Labeille, D	1
Saeed, ZA	1
Frank, WO	1
Young, MD	1
Bardram, L	1
Kitagawa, M	1
Hayakawa, T	1
Kondo, T	1
Shibata, T	1
Sakai, Y	1
Ohno, H	1
Nimura, Y	1
Hayakawa, N	1
Kamiya, J	1
Kondo, S	1
Sölvell, L	1
Steegmüller, KW	1
Van Duijn, B	1
Ypey, DL	1
de Goede, J	1
Verveen, AA	1
Hekkens, W	1
Chremos, AN	1
Peters, MN	1
Cooper, KA	1
Willeford, G	1
Goldfain, D	1
Travers, B	1
Isal, JP	1
Gwee, MC	1
Cheah, LS	1
Wank, SA	2
Slaff, JI	1
Gordillo, J	1
Varas, MJ	1
Luttwak, EM	1
Saltz, NJ	1
Sugarbaker, PH	1
Seaman, JJ	1
Clamp, JR	1
Fairclough, PD	1
Vellar, D	1
Henderson, M	1
Vellar, ID	1
Desmond, P	1
du Toit, DF	1
Louwrens, H	1
Esterhuizen, N	1
Falck, VC	1
du Toit, LB	1
Deveney, KE	1
Britton, ML	1
Waller, ES	1
Andersen, BN	1
Larsen, NE	1
Rune, SJ	1
Worning, H	1