Page last updated: 2024-10-25

cimetidine and Vomiting

cimetidine has been researched along with Vomiting in 18 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"The role of opioid and histaminergic system in morphine induced emesis was investigated in dogs."7.67Role of endogenous opioids and histamine in morphine induced emesis. ( Bhandari, P; Bhargava, KP; Chugh, A; Dixit, KS; Gupta, YK; Seth, SD, 1989)
" In a small open study cimetidine was given to nine patients with acid hypersecretion and endoscopically diagnosed duodenal ulceration who were undergoing haemodialysis."7.65Cimetidine for duodenal ulceration in patients undergoing haemodialysis. ( Buchanan, KD; Doherty, CC; McGeown, MG; O'Connor, FA, 1977)
"The role of opioid and histaminergic system in morphine induced emesis was investigated in dogs."3.67Role of endogenous opioids and histamine in morphine induced emesis. ( Bhandari, P; Bhargava, KP; Chugh, A; Dixit, KS; Gupta, YK; Seth, SD, 1989)
" In a small open study cimetidine was given to nine patients with acid hypersecretion and endoscopically diagnosed duodenal ulceration who were undergoing haemodialysis."3.65Cimetidine for duodenal ulceration in patients undergoing haemodialysis. ( Buchanan, KD; Doherty, CC; McGeown, MG; O'Connor, FA, 1977)
"The diagnosis of gastroesophageal reflux (GER) was made in 28 of the basis of reflux (grade III) on upper gastrointestinal series and the presence of esophagitis either grossly at endoscopy or on esophageal biopsy."1.26Gastroesophageal reflux in the severely retarded who vomit: criteria for and results of surgical intervention in twenty-two patients. ( Ashcraft, E; Byrne, WJ; Euler, AR; Golladay, ES; Nash, DG; Seibert, JJ, 1982)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's3 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bell, MR1
Zalay, AW1
Oesterlin, R1
Clemans, SD1
Dumas, DJ1
Bradford, JC1
Rozitis, J1
Ming-Kai, C1
Ting, Z1
Manchikanti, L2
Kraus, JW1
Edds, SP1
Baker, JP1
Lehot, JJ1
Saunier, CF1
Marrero, TC1
Roush, JR1
Byrne, WJ1
Euler, AR1
Ashcraft, E1
Nash, DG1
Seibert, JJ1
Golladay, ES1
Mooradian, A1
Bdeir, A1
Faraidi, Y1
Mignon, M1
Bonnefond, A1
Gratton, J1
Bonfils, S1
Rampello, L1
Raffaele, R1
Nicoletti, G1
Le Pira, F1
Vecchio, I1
Malaguarnera, M1
Drago, F1
Naveh, Y1
Kleinhaus, U1
Kerner, E1
Berant, M1
Coombs, DW1
Hooper, D1
Colton, T1
Cooper, JR1
Mattsson, JL1
Doherty, CC1
O'Connor, FA1
Buchanan, KD1
McGeown, MG1
al-Ghamdi, MS1
Ibrahim, EM1
al-Idrissi, HY1
al-Khatti, AA1
al-Faraj, A1
Gupta, YK1
Bhandari, P1
Chugh, A1
Seth, SD1
Dixit, KS1
Bhargava, KP1
Wiernik, PH1
Schwartz, EL1
Strauman, JJ1
Dutcher, JP1
Lipton, RB1
Paietta, E1
Cordts, RE1
Yochmowitz, MG1
Hardy, KA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534]29 participants (Actual)Observational2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for cimetidine and Vomiting

ArticleYear
Cimetidine and related drugs in anesthesia.
    Anesthesia and analgesia, 1982, Volume: 61, Issue:7

    Topics: Anesthesia, Obstetrical; Child; Cimetidine; Drug Administration Schedule; Emergencies; Female; Gastr

1982
[Pulmonary aspiration of gastric contents during anesthesia. Physiological and pharmacological data: applications to prevention and treatment].
    Annales francaises d'anesthesie et de reanimation, 1984, Volume: 3, Issue:1

    Topics: Anesthesia, General; Antiemetics; Cimetidine; Gastric Juice; Gastroesophageal Reflux; Humans; Intrao

1984

Trials

3 trials available for cimetidine and Vomiting

ArticleYear
Preanesthetic cimetidine and metoclopramide for acid aspiration prophylaxis in elective surgery.
    Anesthesiology, 1984, Volume: 61, Issue:1

    Topics: Adult; Anesthesia; Cimetidine; Clinical Trials as Topic; Gastric Acid; Gastric Juice; Humans; Inhala

1984
Neurobehavioral syndrome induced by H2-receptor blocker withdrawal: possible role of prolactin.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:1

    Topics: Adult; Anorexia; Antiemetics; Cimetidine; Domperidone; Female; Histamine H2 Antagonists; Humans; Mal

1997
Antiemetic efficacy of cimetidine randomized, double-blind, crossover study with dexamethasone in cancer patients receiving emetogenic chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cimetidine; Dexamethasone; Double-Blind Method; Fema

1991

Other Studies

13 other studies available for cimetidine and Vomiting

ArticleYear
Experimental antiulcer drugs. 1. Indole-1-alkanamides and pyrrole-1-alkanamides.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Dogs; Gastric Juice; Guinea Pigs; Heart Rate; In Vitro Techniques; Indol

1977
Primary hyperparathyroidism presenting as intractable nausea and vomiting.
    Southern medical journal, 2010, Volume: 103, Issue:11

    Topics: Aged; Cimetidine; Female; Histamine H2 Antagonists; Humans; Hyperparathyroidism, Primary; Nausea; Vo

2010
A new series of oral medications for chronic (cancer) pain relief.
    Comprehensive therapy, 1984, Volume: 10, Issue:5

    Topics: Administration, Oral; Aluminum Hydroxide; Analgesics, Opioid; Antacids; Antiemetics; Cimetidine; Coc

1984
Gastroesophageal reflux in the severely retarded who vomit: criteria for and results of surgical intervention in twenty-two patients.
    Surgery, 1982, Volume: 91, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Cimetidine; Female; Follow-Up Studies; Gastroesophageal

1982
Cimetidine for treatment of alkalemia.
    Canadian Medical Association journal, 1982, Sep-15, Volume: 127, Issue:6

    Topics: Aged; Alkalosis; Cimetidine; Guanidines; Humans; Male; Vomiting

1982
Repeated vomiting of gastric juice in a patient with Zollinger-Ellison syndrome. Modifying influence upon clinical features.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:8

    Topics: Cimetidine; Duodenal Neoplasms; Female; Gastric Juice; Humans; Middle Aged; Paraneoplastic Endocrine

1981
Nonspecific duodenitis: an unusual presentation.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:4

    Topics: Abdominal Pain; Adolescent; Anti-Ulcer Agents; Child; Cimetidine; Diarrhea; Duodenitis; Duodenum; En

1997
Acid-aspiration prophylaxis by use of preoperative oral administration of cimetidine.
    Anesthesiology, 1979, Volume: 51, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Anesthesia, Inhalation; Cimetidine; Dose-Response Relations

1979
Control of radiation-induced emesis with promethazine, cimetidine, thiethylperazine, or naloxone.
    American journal of veterinary research, 1979, Volume: 40, Issue:8

    Topics: Animals; Chemoreceptor Cells; Cimetidine; Dog Diseases; Dogs; Guanidines; Male; Naloxone; Promethazi

1979
Cimetidine for duodenal ulceration in patients undergoing haemodialysis.
    British medical journal, 1977, Dec-10, Volume: 2, Issue:6101

    Topics: Adolescent; Adult; Cimetidine; Duodenal Ulcer; Female; Gastric Acidity Determination; Gastrins; Guan

1977
Role of endogenous opioids and histamine in morphine induced emesis.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:1

    Topics: Animals; Cimetidine; Dogs; Endorphins; Histamine; Metiamide; Morphine; Naloxone; Pyrilamine; Vomitin

1989
Phase I clinical and pharmacokinetic study of taxol.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkaloids; Alopecia; Cimetidine; Dexamethasone; Diph

1987
Evaluation of domperidone as a modifier of gamma-radiation-induced emesis.
    International journal of radiation oncology, biology, physics, 1987, Volume: 13, Issue:9

    Topics: Animals; Antiemetics; Cimetidine; Cobalt Radioisotopes; Dexamethasone; Dogs; Domperidone; Drug Thera

1987
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