cimetidine has been researched along with Verruca in 33 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three open-label, uncontrolled studies have documented successful treatment of warts with cimetidine, whereas two placebo-controlled, double-blind studies and two open-label comparative trials have failed to demonstrate efficacy." | 9.09 | Cimetidine therapy for recalcitrant warts in adults: is it any better than placebo? ( Gibney, MD; Glaser, DA; Harrison, BR; Rogers, CJ; Siegfried, EC, 1999) |
| "The immunomodulatory actions of cimetidine, an H2-receptor antagonist, and its use in the treatment of viral warts has been described previously but its effectiveness is still debated." | 9.09 | Treatment of viral warts with cimetidine: an open-label study. ( Gooptu, C; Higgins, CR; James, MP, 2000) |
| "The aim of the present study was to determine whether cimetidine is effective in the treatment of warts." | 9.08 | Cimetidine therapy for warts: a placebo-controlled, double-blind study. ( Alpsoy, E; Basaran, E; Yilmaz, E, 1996) |
| "An open-label study was conducted to determine the safety and efficacy of high-dose cimetidine in 20 adult patients with recalcitrant warts." | 9.08 | Cimetidine therapy for recalcitrant warts in adults. ( Glass, AT; Solomon, BA, 1996) |
| "Oral cimetidine for the treatment of verruca continues to be a topic of discussion and controversy." | 8.80 | Cimetidine and a delayed hypersensitivity reaction. ( Donohoe, S; Eberly, M; Evans, RD; Yoho, R, 2000) |
| "However, treatment for warts can be challenging, and there is no single method of treatment that is universally effective." | 5.36 | Treatment of recalcitrant periungual warts with cimetidine in pediatrics. ( Cheng, YW; Chern, E, 2010) |
| "Cimetidine is an H2-receptor antagonist which is mainly used to treat gastrointestinal diseases." | 5.29 | The effect of cimetidine on verruca plana juvenilis: clinical trials in six patients. ( Choi, YS; Hann, SK; Park, YK, 1993) |
| "Three open-label, uncontrolled studies have documented successful treatment of warts with cimetidine, whereas two placebo-controlled, double-blind studies and two open-label comparative trials have failed to demonstrate efficacy." | 5.09 | Cimetidine therapy for recalcitrant warts in adults: is it any better than placebo? ( Gibney, MD; Glaser, DA; Harrison, BR; Rogers, CJ; Siegfried, EC, 1999) |
| "The immunomodulatory actions of cimetidine, an H2-receptor antagonist, and its use in the treatment of viral warts has been described previously but its effectiveness is still debated." | 5.09 | Treatment of viral warts with cimetidine: an open-label study. ( Gooptu, C; Higgins, CR; James, MP, 2000) |
| "The aim of the present study was to determine whether cimetidine is effective in the treatment of warts." | 5.08 | Cimetidine therapy for warts: a placebo-controlled, double-blind study. ( Alpsoy, E; Basaran, E; Yilmaz, E, 1996) |
| "An open-label study was conducted to determine the safety and efficacy of high-dose cimetidine in 20 adult patients with recalcitrant warts." | 5.08 | Cimetidine therapy for recalcitrant warts in adults. ( Glass, AT; Solomon, BA, 1996) |
| "Relevant publications were identified through a systematic search of PubMed English-language literature using the MeSH terms and key words cimetidine, ranitidine, famotidine, nizatidine, histamine H2-antagonists, and warts." | 4.84 | Use of histamine2-antagonists for the treatment of verruca vulgaris. ( Fit, KE; Williams, PC, 2007) |
| "Oral cimetidine for the treatment of verruca continues to be a topic of discussion and controversy." | 4.80 | Cimetidine and a delayed hypersensitivity reaction. ( Donohoe, S; Eberly, M; Evans, RD; Yoho, R, 2000) |
| "Treatment-resistant warts are a common and frustrating problem for patients, parents, and providers alike." | 2.45 | Immunotherapy for childhood warts. ( Burkhart, CN; Dasher, DA; Morrell, DS, 2009) |
| "Warts are caused by the human papillomavirus (HPV), of which there are over 100 types, which probably infects the skin via areas of minimal trauma." | 2.45 | Warts (non-genital). ( Loo, SK; Tang, WY, 2009) |
| "Warts and molluscum contagiosum are common skin diseases in children and are usually self-limiting." | 2.43 | How and when to treat molluscum contagiosum and warts in children. ( Smolinski, KN; Yan, AC, 2005) |
| "However, treatment for warts can be challenging, and there is no single method of treatment that is universally effective." | 1.36 | Treatment of recalcitrant periungual warts with cimetidine in pediatrics. ( Cheng, YW; Chern, E, 2010) |
| "Cimetidine is an H2-receptor antagonist which is mainly used to treat gastrointestinal diseases." | 1.29 | The effect of cimetidine on verruca plana juvenilis: clinical trials in six patients. ( Choi, YS; Hann, SK; Park, YK, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (42.42) | 18.2507 |
| 2000's | 15 (45.45) | 29.6817 |
| 2010's | 3 (9.09) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Ramos-Arancibia, N | 1 |
| Varas, C | 1 |
| Rozas-Muñoz, E | 1 |
| Palioura, S | 1 |
| Nikpoor, N | 1 |
| Yoo, SH | 1 |
| Dasher, DA | 1 |
| Burkhart, CN | 1 |
| Morrell, DS | 1 |
| Chern, E | 1 |
| Cheng, YW | 1 |
| Simonart, T | 1 |
| de Maertelaer, V | 1 |
| Loo, SK | 1 |
| Tang, WY | 1 |
| Kharfi, M | 1 |
| Chtourou, O | 1 |
| Kamoun, F | 1 |
| Mokhtar, I | 1 |
| Fazaa, B | 1 |
| Ben Salem, M | 1 |
| Kamoun, MR | 1 |
| Majewski, S | 1 |
| Jablonska, S | 1 |
| Bigby, M | 3 |
| Gibbs, S | 3 |
| Harvey, I | 2 |
| Sterling, J | 2 |
| Smolinski, KN | 1 |
| Yan, AC | 1 |
| Sontheimer, D | 1 |
| Brown, ML | 1 |
| Paulson, CP | 1 |
| Fit, KE | 1 |
| Williams, PC | 1 |
| Choi, YS | 1 |
| Hann, SK | 1 |
| Park, YK | 1 |
| Orlow, SJ | 1 |
| Paller, A | 1 |
| Ronna, T | 1 |
| Lebwohl, M | 1 |
| Yilmaz, E | 1 |
| Alpsoy, E | 1 |
| Basaran, E | 1 |
| Glass, AT | 1 |
| Solomon, BA | 1 |
| Bauman, C | 1 |
| Francis, JS | 1 |
| Vanderhooft, S | 1 |
| Sybert, VP | 1 |
| Paller, AS | 1 |
| Wargon, O | 1 |
| Mahoney, JM | 1 |
| Sáenz-Santamaría, MC | 1 |
| Gilaberte, Y | 1 |
| Karabulut, AA | 1 |
| Sahin, S | 1 |
| Ekşioglu, M | 1 |
| Fischer, G | 1 |
| Rogers, M | 1 |
| Parsad, D | 1 |
| Saini, R | 1 |
| Negi, KS | 1 |
| Rogers, CJ | 1 |
| Gibney, MD | 1 |
| Siegfried, EC | 2 |
| Harrison, BR | 1 |
| Glaser, DA | 1 |
| Evans, RD | 1 |
| Yoho, R | 1 |
| Eberly, M | 1 |
| Donohoe, S | 1 |
| Gooptu, C | 1 |
| Higgins, CR | 1 |
| James, MP | 1 |
| Allen, AL | 1 |
| Lee, SH | 1 |
| Rose, B | 1 |
| Thompson, CH | 1 |
| Cossart, Y | 1 |
| Suhonen, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oral Zinc Sulfate for the Treatment of High Risk Cervical HPV Versus Placebo[NCT03404310] | 21 participants (Actual) | Interventional | 2017-10-24 | Terminated (stopped due to Lack of recruitment) | |||
| Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts, A Randomized Clinical Trial[NCT03158168] | Phase 3 | 70 participants (Anticipated) | Interventional | 2018-03-01 | Recruiting | ||
| Evaluation of Combined Treatment With Er:YAG Laser and Long-pulsed Nd:YAG Laser for the Treatment of Recalcitrant Warts: a Prospective Randomized Controlled Trial[NCT05768893] | 24 participants (Actual) | Interventional | 2022-05-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for cimetidine and Verruca
| Article | Year |
|---|---|
Immunotherapy for childhood warts.
Topics: Adjuvants, Immunologic; Aminoquinolines; Antigens; Child; Child, Preschool; Cimetidine; Cyclobutanes | 2009 |
Systemic treatments for cutaneous warts: a systematic review.
Topics: Adjuvants, Immunologic; Cimetidine; Enzyme Inhibitors; Homeopathy; Humans; Levamisole; Trace Element | 2012 |
Warts (non-genital).
Topics: Administration, Oral; Bandages; Bleomycin; Cimetidine; Cryosurgery; Cryotherapy; Humans; Warts; Zinc | 2009 |
Warts.
Topics: Bleomycin; Cimetidine; Cryotherapy; Humans; Laser Therapy; Warts | 2003 |
Warts.
Topics: Bleomycin; Cimetidine; Cryotherapy; Humans; Salicylic Acid; Warts | 2004 |
How and when to treat molluscum contagiosum and warts in children.
Topics: Adhesives; Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Cantharidin; Child; Cim | 2005 |
Clinical inquiries. Are oral agents effective for the treatment of verruca vulgaris?
Topics: Adjuvants, Immunologic; Administration, Oral; Cimetidine; Humans; Levamisole; Practice Guidelines as | 2006 |
Warts.
Topics: Antibiotics, Antineoplastic; Bleomycin; Cimetidine; Cryotherapy; Humans; Occlusive Dressings; Salicy | 2005 |
Use of histamine2-antagonists for the treatment of verruca vulgaris.
Topics: Cimetidine; Histamine H2 Antagonists; Humans; Randomized Controlled Trials as Topic; Receptors, Hist | 2007 |
Cimetidine and a delayed hypersensitivity reaction.
Topics: Adjuvants, Immunologic; Administration, Oral; Adult; Cimetidine; Drug Eruptions; Edema; Female; Foll | 2000 |
What's new in human papillomavirus infection.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminoquinolines; Child; Cidofovir; Cimetidine; Cyto | 2000 |
[Treatment of warts].
Topics: Adjuvants, Immunologic; Administration, Oral; Administration, Topical; Bleomycin; Cimetidine; Cryosu | 2000 |
11 trials available for cimetidine and Verruca
| Article | Year |
|---|---|
[Cimetidine therapy for multiple warts in children].
Topics: Adjuvants, Immunologic; Administration, Oral; Child; Cimetidine; Double-Blind Method; Female; Humans | 2002 |
Cimetidine therapy for warts: a placebo-controlled, double-blind study.
Topics: Adolescent; Adult; Child; Child, Preschool; Cimetidine; Dermatologic Agents; Double-Blind Method; Fe | 1996 |
Cimetidine therapy for recalcitrant warts in adults.
Topics: Adult; Cimetidine; Female; Histamine H2 Antagonists; Humans; Male; Middle Aged; Warts | 1996 |
Cimetidine therapy for multiple viral warts in children.
Topics: Adolescent; Child; Child, Preschool; Cimetidine; Follow-Up Studies; Foot Dermatoses; Hand Dermatoses | 1996 |
Cimetidine and warts.
Topics: Adult; Child; Cimetidine; Humans; Prospective Studies; Skin Diseases; Warts | 1997 |
Is cimetidine effective for nongenital warts: a double-blind, placebo-controlled study.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Child; Cimetidine; Double-Blind Method; Female; Humans; M | 1997 |
Cimetidine therapy for warts in children.
Topics: Adolescent; Antiviral Agents; Child; Cimetidine; Female; Humans; Male; Warts | 1997 |
Comparison of combination of cimetidine and levamisole with cimetidine alone in the treatment of recalcitrant warts.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Child; Cimetidine; Double-Blind Method; Drug Therapy, Com | 1999 |
Cimetidine therapy for recalcitrant warts in adults: is it any better than placebo?
Topics: Adult; Cimetidine; Double-Blind Method; Female; Histamine H2 Antagonists; Humans; Male; Warts | 1999 |
Treatment of viral warts with cimetidine: an open-label study.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Child; Child, Preschool; Cimetidine; Facial Dermatoses; F | 2000 |
Plantar warts of defined aetiology in adults and unresponsiveness to low dose cimetidine.
Topics: Adjuvants, Immunologic; Adult; Cimetidine; Dose-Response Relationship, Drug; Female; Foot Diseases; | 2001 |
10 other studies available for cimetidine and Verruca
| Article | Year |
|---|---|
Severe and recalcitrant periungual warts in a child successfully treated with cimetidine.
Topics: Child; Cimetidine; Family; Humans; Nail Diseases; Warts | 2021 |
Chronic Conjunctivitis and "Warts".
Topics: Administration, Oral; Child; Chronic Disease; Cimetidine; Conjunctivitis, Viral; Eye Infections, Vir | 2015 |
Treatment of recalcitrant periungual warts with cimetidine in pediatrics.
Topics: Child; Cimetidine; Dermatologic Agents; Female; Humans; Nail Diseases; Severity of Illness Index; Ti | 2010 |
New treatments for cutaneous human papillomavirus infection.
Topics: Cimetidine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Immunotherapy; Inte | 2004 |
The effect of cimetidine on verruca plana juvenilis: clinical trials in six patients.
Topics: Administration, Oral; Adult; Cimetidine; Dinitrochlorobenzene; Drug Evaluation; Drug Tolerance; Fema | 1993 |
Cimetidine therapy for multiple viral warts in children.
Topics: Administration, Oral; Adolescent; Child; Cimetidine; Facial Dermatoses; Female; Follow-Up Studies; F | 1993 |
Cimetidine therapy for plantar warts.
Topics: Adult; Cimetidine; Female; Foot Dermatoses; Histamine H2 Antagonists; Humans; Warts | 1995 |
Cimetidine for the treatment of warts.
Topics: Adult; Child; Child, Preschool; Cimetidine; Clinical Trials as Topic; Histamine H2 Antagonists; Huma | 1996 |
Cimetidine for mucosal warts in an HIV positive adult.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anus Diseases; Cimetidine; Follo | 1996 |
Oral cimetidine and the treatment of verrucae.
Topics: Administration, Oral; Adolescent; Adult; Anti-Ulcer Agents; Child; Cimetidine; Female; Foot Diseases | 1996 |