cimetidine has been researched along with Uremia in 14 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cimetidine treatment caused no changes in serum calcium, phosphorus, or iPTH or in urinary cAMP (expressed as nanomoles per g creatinine)." | 5.26 | Cimetidine treatment of azotemic secondary hyperparathyroidism. ( Heath, H; Johnson, WJ; Robinson, MF, 1982) |
| "Cimetidine has been shown to increase the burst-promoting activity (BPA) of uremic T lymphocytes and to partially improve the BPA of normal T lymphocytes preincubated with uremic serum." | 1.28 | Effect of cimetidine on peripheral blood lymphocytes from chronic uremic patients: improvement of burst-promoting activity. ( Casti, P; Gurreri, G; Mela, S; Moccia, F; Morra, L; Ponassi, GA, 1992) |
| "Cimetidine treatment caused no changes in serum calcium, phosphorus, or iPTH or in urinary cAMP (expressed as nanomoles per g creatinine)." | 1.26 | Cimetidine treatment of azotemic secondary hyperparathyroidism. ( Heath, H; Johnson, WJ; Robinson, MF, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cunningham, J | 1 |
| Segre, G | 1 |
| Slatopolsky, E | 1 |
| Robinson, MF | 1 |
| Johnson, WJ | 1 |
| Heath, H | 1 |
| Zazgornik, J | 1 |
| Dudczak, R | 1 |
| Fuhrmann, M | 1 |
| Marosi, L | 1 |
| Minar, E | 1 |
| Balcke, P | 1 |
| Rudnick, MR | 1 |
| Bastl, CP | 1 |
| Elfenbein, IB | 1 |
| Sirota, RA | 1 |
| Yudis, M | 1 |
| Narins, RG | 1 |
| Kovarik, J | 1 |
| Graf, H | 1 |
| Woloszczuk, W | 1 |
| Stummvoll, HK | 1 |
| Sebert, JL | 2 |
| Decourcelles, PH | 2 |
| Morinière, P | 3 |
| Calmette, C | 1 |
| Gueris, J | 2 |
| Makdassi, R | 3 |
| Khassouf, J | 2 |
| Andrejak, M | 3 |
| Fournier, A | 3 |
| Jacob, AI | 3 |
| Gavellas, G | 2 |
| Canterbury, JM | 2 |
| Lambert, PW | 2 |
| Bourgoignie, JJ | 3 |
| de Fremont, JF | 2 |
| Fiore, CE | 1 |
| Malatino, LS | 1 |
| Tamburino, C | 1 |
| Lunetta, M | 1 |
| Heynen, G | 1 |
| Decourcelle, PH | 1 |
| Coevoet, B | 1 |
| Kassouf, J | 1 |
| Roussel, A | 1 |
| Gheerbrand, JD | 1 |
| Lanier, D | 1 |
| Canterbury, J | 1 |
| Zappacosta, AR | 1 |
| Hauss, D | 1 |
| Morra, L | 1 |
| Moccia, F | 1 |
| Gurreri, G | 1 |
| Ponassi, GA | 1 |
| Casti, P | 1 |
| Mela, S | 1 |
1 trial available for cimetidine and Uremia
| Article | Year |
|---|---|
Acute effect of cimetidine and pirenzepine on plasma parathyroid hormone and calcitonin in haemodialyzed patients.
Topics: Adult; Aged; Benzodiazepinones; Calcitonin; Cimetidine; Electrolytes; Female; Humans; Male; Middle A | 1983 |
13 other studies available for cimetidine and Uremia
| Article | Year |
|---|---|
Histamine H2 receptor blockade in patients with hyperparathyroidism.
Topics: Cimetidine; Humans; Hyperparathyroidism; Hyperparathyroidism, Secondary; Parathyroid Hormone; Raniti | 1984 |
Cimetidine treatment of azotemic secondary hyperparathyroidism.
Topics: Adult; Cimetidine; Creatinine; Cyclic AMP; Female; Guanidines; Humans; Hyperparathyroidism, Secondar | 1982 |
Cimetidine-induced acute renal failure.
Topics: Acute Kidney Injury; Aged; Cimetidine; Guanidines; Humans; Male; Middle Aged; Nephritis, Interstitia | 1982 |
Cimetidine in secondary hyperparathyroidism.
Topics: Cimetidine; Guanidines; Humans; Hyperparathyroidism, Secondary; Uremia | 1982 |
Cimetidine and circulating calciotropic hormone levels in uremic patients: evidence for a suppressive effect on calcitonin secretion.
Topics: Adult; Aged; Calcitonin; Cimetidine; Drug Evaluation; Female; Guanidines; Humans; Hypoparathyroidism | 1982 |
Phosphate homeostasis in cimetidine treated uremic dogs.
Topics: Animals; Calcium; Cimetidine; Dogs; Female; Guanidines; Homeostasis; Parathyroid Hormone; Phosphates | 1982 |
Effects of oral cimetidine on parathyroid hormone and calcitonin plasma levels in uremic patients.
Topics: Administration, Oral; Adult; Aged; Calcitonin; Cimetidine; Female; Guanidines; Humans; Male; Middle | 1982 |
Reversal of secondary hyperparathyroidism by cimetidine in chronically uremic dogs.
Topics: Animals; Calcium; Cimetidine; Dogs; Female; Guanidines; Homeostasis; Hyperparathyroidism, Secondary; | 1981 |
Cimetidine-induced PTH variations in uraemic patients evaluated with the aid of antisera against the terminal carboxyl and amino groups of the hormone molecule.
Topics: Adult; Alkaline Phosphatase; Animals; Cimetidine; Guanidines; Humans; Kidney Failure, Chronic; Middl | 1981 |
Blockers of beta and H2 receptors and secondary hyperparathyroidism in uraemia.
Topics: Adult; Aged; Atenolol; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism, Secondary; Male; | 1981 |
Reduction by cimetidine of serum parathyroid hormone levels in uremic patients.
Topics: Adult; Aged; Calcium; Cimetidine; Female; Guanidines; Humans; Hyperparathyroidism, Secondary; Male; | 1980 |
Cimetidine doesn't help pruritus of uremia.
Topics: Cimetidine; Guanidines; Humans; Pruritus; Uremia | 1979 |
Effect of cimetidine on peripheral blood lymphocytes from chronic uremic patients: improvement of burst-promoting activity.
Topics: Adult; Aged; Cells, Cultured; Cimetidine; Colony-Forming Units Assay; Erythroid Precursor Cells; Fem | 1992 |