cimetidine has been researched along with Thrombopenia in 31 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In October 1994, thrombocytopenia gradually progressed, and we halted the administration of cimetidine to ranitidine." | 7.69 | [Hemolytic anemia and thrombocytopenia induced by cimetidine: recurrence with ranitidine administration]. ( Kura, T; Mogi, Y; Niitsu, Y; Takimoto, R, 1997) |
| "We report the case of a patient with peptic ulcer disease who developed cimetidine-induced thrombocytopenia." | 7.68 | Cimetidine and ranitidine may not cross-react to cause thrombocytopenia. ( Seror, D; Shalev, O, 1991) |
| "A rare case of thrombocytopenia associated with ranitidine is described." | 7.67 | Thrombocytopenia associated with hypersensitivity to ranitidine: possible cross-reactivity with cimetidine. ( Gafter, U; Komlos, L; Levi, J; Livni, E; Zevin, D, 1989) |
| "Combined use of cimetidine and phenytoin among 1512 neurosurgical patients has led to severe thrombocytopenia in 4 patients." | 7.67 | Severe thrombocytopenia due to combined cimetidine and phenytoin therapy. ( Chan, KH; Mann, KS; Yue, CP, 1987) |
| "A 67-year-old man developed a sudden onset of severe isolated thrombocytopenia (platelet count, 1000/mm3) after 10 days of phenytoin administration as a prophylactic measure prior to craniotomy." | 7.67 | Severe thrombocytopenia associated with phenytoin and cimetidine therapy. ( Brown, FD; Lichtor, T; Wong, YY, 1985) |
| "A case of thrombocytopenia associated with cimetidine administration in a 65-year-old white female with recurrent adenocarcinoma is reported." | 7.66 | Cimetidine-associated thrombocytopenia. ( Delaney, JP; Mann, HJ; Miller, JB; Schneider, JR, 1983) |
| "This report described a case of cimetidine-induced thrombocytopenia documented by accidental rechallenge." | 7.66 | Cimetidine-induced thrombocytopenia. ( Glotzbach, RE, 1982) |
| " In October 1994, thrombocytopenia gradually progressed, and we halted the administration of cimetidine to ranitidine." | 3.69 | [Hemolytic anemia and thrombocytopenia induced by cimetidine: recurrence with ranitidine administration]. ( Kura, T; Mogi, Y; Niitsu, Y; Takimoto, R, 1997) |
| "We report the case of a patient with peptic ulcer disease who developed cimetidine-induced thrombocytopenia." | 3.68 | Cimetidine and ranitidine may not cross-react to cause thrombocytopenia. ( Seror, D; Shalev, O, 1991) |
| "A rare case of thrombocytopenia associated with ranitidine is described." | 3.67 | Thrombocytopenia associated with hypersensitivity to ranitidine: possible cross-reactivity with cimetidine. ( Gafter, U; Komlos, L; Levi, J; Livni, E; Zevin, D, 1989) |
| "Combined use of cimetidine and phenytoin among 1512 neurosurgical patients has led to severe thrombocytopenia in 4 patients." | 3.67 | Severe thrombocytopenia due to combined cimetidine and phenytoin therapy. ( Chan, KH; Mann, KS; Yue, CP, 1987) |
| "A 67-year-old man developed a sudden onset of severe isolated thrombocytopenia (platelet count, 1000/mm3) after 10 days of phenytoin administration as a prophylactic measure prior to craniotomy." | 3.67 | Severe thrombocytopenia associated with phenytoin and cimetidine therapy. ( Brown, FD; Lichtor, T; Wong, YY, 1985) |
| "A case of thrombocytopenia associated with cimetidine administration in a 65-year-old white female with recurrent adenocarcinoma is reported." | 3.66 | Cimetidine-associated thrombocytopenia. ( Delaney, JP; Mann, HJ; Miller, JB; Schneider, JR, 1983) |
| "This report described a case of cimetidine-induced thrombocytopenia documented by accidental rechallenge." | 3.66 | Cimetidine-induced thrombocytopenia. ( Glotzbach, RE, 1982) |
| "A 67-year-old man with a bleeding ulcer developed fever, thrombocytopenia, and neutropenia with eosinophilia coincidental to receiving 3600 mg of cimetidine." | 3.66 | Cimetidine and hematologic suppression: things are not always as they appear. ( Castell, DO; Gerhardt, DC; Pasquale, DN; Richter, JE, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (70.97) | 18.7374 |
| 1990's | 8 (25.81) | 18.2507 |
| 2000's | 1 (3.23) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mann, HJ | 1 |
| Schneider, JR | 1 |
| Miller, JB | 1 |
| Delaney, JP | 1 |
| Reddy, J | 1 |
| Bailey, RR | 1 |
| Isaacs, AJ | 1 |
| Collen, MJ | 1 |
| Glotzbach, RE | 1 |
| Mar, DD | 1 |
| Brandstetter, RD | 1 |
| Miskovitz, PF | 1 |
| Fotino, M | 1 |
| Chandrasekhara, KL | 1 |
| Iyer, SK | 1 |
| Macchia, RJ | 1 |
| Denis, J | 1 |
| Thierman-Duffaud, D | 1 |
| Opolon, P | 1 |
| Levy, VG | 1 |
| Selker, HP | 1 |
| Rosenbloom, BE | 1 |
| Weinstein, IM | 1 |
| Yates, VM | 1 |
| Kerr, RE | 1 |
| Richter, JE | 1 |
| Gerhardt, DC | 1 |
| Pasquale, DN | 1 |
| Castell, DO | 1 |
| Gurzó, M | 1 |
| Varga, G | 1 |
| Dobos, K | 1 |
| Náfrádi, J | 1 |
| Petri, A | 1 |
| Arbiser, JL | 1 |
| Goldstein, AM | 1 |
| Gordon, D | 1 |
| Hatton, J | 1 |
| Lu, WY | 1 |
| Rhoney, DH | 1 |
| Tibbs, PA | 1 |
| Dempsey, RJ | 1 |
| Young, B | 1 |
| Takimoto, R | 1 |
| Mogi, Y | 1 |
| Kura, T | 1 |
| Niitsu, Y | 1 |
| Gentilini, G | 1 |
| Curtis, BR | 1 |
| Aster, RH | 1 |
| Wade, EE | 1 |
| Rebuck, JA | 1 |
| Healey, MA | 1 |
| Rogers, FB | 1 |
| James, C | 1 |
| Prout, BJ | 1 |
| Idvall, J | 1 |
| McDaniel, JL | 1 |
| Stein, JJ | 1 |
| Rate, R | 1 |
| Bonnell, M | 1 |
| Chervenak, C | 1 |
| Pavinich, G | 1 |
| Raya Sánchez, JM | 1 |
| Jorge Hernández, JA | 1 |
| Santolaria Fernández, FJ | 1 |
| Hernández Nieto, L | 1 |
| Shalev, O | 1 |
| Seror, D | 1 |
| Bourghol, A | 1 |
| Rindone, JP | 1 |
| Gafter, U | 1 |
| Zevin, D | 1 |
| Komlos, L | 1 |
| Livni, E | 1 |
| Levi, J | 1 |
| Harats, N | 1 |
| Oren, R | 1 |
| Heyman, A | 1 |
| Naparstek, Y | 1 |
| Habel, A | 1 |
| Murray, N | 1 |
| Yue, CP | 1 |
| Mann, KS | 1 |
| Chan, KH | 1 |
| Ogawa, T | 1 |
| Tanaka, M | 1 |
| Araki, N | 1 |
| Yogo, H | 1 |
| Naito, K | 1 |
| Yamada, I | 1 |
| Wong, YY | 1 |
| Lichtor, T | 1 |
| Brown, FD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit[NCT00633035] | Phase 4 | 60 participants (Actual) | Interventional | 2007-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cimetidine and Thrombopenia
| Article | Year |
|---|---|
H(2) antagonist-induced thrombocytopenia: is this a real phenomenon?
Topics: Cimetidine; Critical Care; Famotidine; Histamine H2 Antagonists; Humans; Peptic Ulcer; Ranitidine; R | 2002 |
30 other studies available for cimetidine and Thrombopenia
| Article | Year |
|---|---|
Cimetidine-associated thrombocytopenia.
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Platelet Count; Thrombocytopenia; Time Factors | 1983 |
Cimetidine and thrombocytopenia.
Topics: Cimetidine; Female; Graft Rejection; Guanidines; Humans; Kidney Transplantation; Middle Aged; Thromb | 1980 |
Cimetidine and thrombocytopenia.
Topics: Adult; Cimetidine; Guanidines; Humans; Male; Platelet Count; Sarcoidosis; Thrombocytopenia | 1980 |
Cimetidine-associated thrombocytopenia and leukopenia.
Topics: Cimetidine; Guanidines; Humans; Leukopenia; Male; Middle Aged; Thrombocytopenia | 1980 |
Cimetidine-induced thrombocytopenia.
Topics: Blood Platelets; Cimetidine; Guanidines; Humans; Male; Middle Aged; Serotonin; Stomach Ulcer; Thromb | 1982 |
Cimetidine-induced, immune-mediated leukopenia and thrombocytopenia.
Topics: Agglutination Tests; Agglutinins; Cimetidine; Female; Guanidines; Humans; Leukocytes; Leukopenia; Mi | 1982 |
[Thrombocytopenia during cimetidine therapy].
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Thrombocytopenia | 1982 |
Leucopenia and thrombocytopenia with cimetidine.
Topics: Cimetidine; Female; Guanidines; Humans; Leukopenia; Middle Aged; Thrombocytopenia | 1981 |
[Thrombopenia induced by cimetidine].
Topics: Cimetidine; Guanidines; Humans; Male; Middle Aged; Thrombocytopenia | 1981 |
Cimetidine and cytopenia.
Topics: Aged; Agranulocytosis; Bone Marrow Cells; Cimetidine; Female; Guanidines; Humans; In Vitro Technique | 1981 |
Cimetidine and thrombocytopenia.
Topics: Aged; Cimetidine; Guanidines; Humans; Male; Psoriasis; Thrombocytopenia | 1980 |
Cimetidine and hematologic suppression: things are not always as they appear.
Topics: Aged; Agranulocytosis; Blood Transfusion; Cimetidine; Duodenal Ulcer; Eosinophilia; Fever; Guanidine | 1980 |
[Therapeutic possibilities in the management of gastrointestinal bleeding in thrombocytopenic patients].
Topics: Aged; Blood Coagulation Disorders; Blood Transfusion; Cimetidine; Ethamsylate; Gastrointestinal Hemo | 1994 |
Thrombocytopenia following administration of phenytoin, dexamethasone and cimetidine: a case report and a potential mechanism.
Topics: Aged; Aged, 80 and over; Cimetidine; Dexamethasone; Drug Interactions; Female; Humans; Phenytoin; Th | 1993 |
A step-wise protocol for stress ulcer prophylaxis in the neurosurgical intensive care unit.
Topics: Adult; Cimetidine; Clinical Protocols; Critical Care; Drug Therapy, Combination; Gastric Acid; Gastr | 1996 |
[Hemolytic anemia and thrombocytopenia induced by cimetidine: recurrence with ranitidine administration].
Topics: Aged; Anemia, Hemolytic; Anti-Ulcer Agents; Cimetidine; Drug Interactions; Female; Histamine H2 Anta | 1997 |
An antibody from a patient with ranitidine-induced thrombocytopenia recognizes a site on glycoprotein IX that is a favored target for drug-induced antibodies.
Topics: Aged; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Rea | 1998 |
Marrow suppression and intravenous cimetidine.
Topics: Adult; Bone Marrow; Cimetidine; Guanidines; Humans; Injections, Intravenous; Leukopenia; Male; Throm | 1978 |
Cimetidine-associated thrombocytopenia.
Topics: Aged; Blood Platelets; Cimetidine; Guanidines; Humans; Male; Middle Aged; Thrombocytopenia | 1979 |
Thrombocytopenia with cimetidine therapy.
Topics: Aged; Cimetidine; Female; Guanidines; Humans; Thrombocytopenia | 1979 |
Cimetidine and hematologic effects.
Topics: Agranulocytosis; Anemia, Hemolytic; Cimetidine; Female; Guanidines; Humans; Middle Aged; Thrombocyto | 1979 |
[Severe thrombocytopenia associated with cimetidine. A new case].
Topics: Aged; Cimetidine; Humans; Male; Thrombocytopenia | 1992 |
Cimetidine and ranitidine may not cross-react to cause thrombocytopenia.
Topics: Aged; Cimetidine; Duodenal Ulcer; Humans; Male; Peptic Ulcer Hemorrhage; Ranitidine; Thrombocytopeni | 1991 |
Cimetidine-associated thrombocytopenia.
Topics: Aged; Cimetidine; Humans; Male; Thrombocytopenia | 1990 |
Thrombocytopenia associated with hypersensitivity to ranitidine: possible cross-reactivity with cimetidine.
Topics: Cell Migration Inhibition; Cimetidine; Cross Reactions; Drug Hypersensitivity; Humans; Immunoglobuli | 1989 |
Cimetidine-induced thrombocytopenia in a cirrhotic patient.
Topics: Cimetidine; Female; Fibrosis; Humans; Middle Aged; Thrombocytopenia | 1989 |
Ranitidine in the newborn.
Topics: Cimetidine; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Ranitidine; Thrombocytopenia | 1988 |
Severe thrombocytopenia due to combined cimetidine and phenytoin therapy.
Topics: Adult; Aged; Bone Marrow Diseases; Cimetidine; Humans; Male; Phenytoin; Thrombocytopenia | 1987 |
[A case of cimetidine-induced thrombocytopenia].
Topics: Adult; Cimetidine; Humans; Male; Stomach Ulcer; Thrombocytopenia | 1986 |
Severe thrombocytopenia associated with phenytoin and cimetidine therapy.
Topics: Aged; Cimetidine; Humans; Male; Phenytoin; Thrombocytopenia | 1985 |