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cimetidine and Substance Withdrawal Syndrome

cimetidine has been researched along with Substance Withdrawal Syndrome in 9 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine was without effect on wet-dog shakes, burrowing, and body weight loss."1.29The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice. ( el Kadi, AO; Sharif, SI, 1996)
"Our review of published material, manufacturer's files, and submissions to the United States Food and Drug Administration indicates that cimetidine is safe for short term use (up to 8 weeks)."1.26Safety of cimetidine. ( Kruss, DM; Littman, A, 1978)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
el Kadi, AO1
Sharif, SI1
Rampello, L1
Raffaele, R1
Nicoletti, G1
Le Pira, F1
Vecchio, I1
Malaguarnera, M1
Drago, F1
Hoste, P1
Ingels, J1
Elewaut, A1
Barbier, F1
Goodwin, JS1
Ahmad, S1
McColl, KE1
Kruss, DM1
Littman, A1
Yamaji, Y1
Omata, T1
Abe, T1
Yoshida, A1
Ueki, S1
Aita, H1
Morita, H1
Chaki, K1
Segawa, Y1
Kurimoto, T1
McMahon, T1

Reviews

1 review available for cimetidine and Substance Withdrawal Syndrome

ArticleYear
Side effects of cimetidine.
    Southern medical journal, 1979, Volume: 72, Issue:5

    Topics: Acute Disease; Aged; Agranulocytosis; Burns; Central Nervous System; Cimetidine; Female; Glucose; Gu

1979

Trials

1 trial available for cimetidine and Substance Withdrawal Syndrome

ArticleYear
Neurobehavioral syndrome induced by H2-receptor blocker withdrawal: possible role of prolactin.
    Clinical neuropharmacology, 1997, Volume: 20, Issue:1

    Topics: Adult; Anorexia; Antiemetics; Cimetidine; Domperidone; Female; Histamine H2 Antagonists; Humans; Mal

1997

Other Studies

7 other studies available for cimetidine and Substance Withdrawal Syndrome

ArticleYear
The role of histaminergic-noradrenergic axis in naloxone-induced withdrawal symptoms in mice.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpheniramine; Cimetidine; Dose-Response Relationship, Drug; Histamine

1996
Duodenal perforation after cimetidine.
    Lancet (London, England), 1978, Mar-25, Volume: 1, Issue:8065

    Topics: Adolescent; Cimetidine; Duodenal Ulcer; Guanidines; Humans; Male; Peptic Ulcer Hemorrhage; Peptic Ul

1978
Cimetidine and delayed hypersensitivity.
    Lancet (London, England), 1978, Apr-29, Volume: 1, Issue:8070

    Topics: Cimetidine; Duodenal Ulcer; Guanidines; Humans; Hypersensitivity, Delayed; Substance Withdrawal Synd

1978
Cimetidine and duodenal ulcer.
    British medical journal, 1979, Mar-17, Volume: 1, Issue:6165

    Topics: Adult; Cimetidine; Duodenal Ulcer; Female; Guanidines; Humans; Substance Withdrawal Syndrome

1979
Safety of cimetidine.
    Gastroenterology, 1978, Volume: 74, Issue:2 Pt 2

    Topics: Aspartate Aminotransferases; Cimetidine; Creatinine; Drug Interactions; Guanidines; Humans; Liver; R

1978
Effects of successive doses of nizatidine, cimetidine and ranitidine on serum gastrin level and gastric acid secretion.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:9

    Topics: Animals; Cimetidine; Gastric Acid; Gastrins; Male; Nizatidine; Pylorus; Ranitidine; Rats; Rats, Inbr

1991
Dyskinesia associated with amoxapine withdrawal and use of carbamazepine and antihistamines.
    Psychosomatics, 1986, Volume: 27, Issue:2

    Topics: Amoxapine; Carbamazepine; Cimetidine; Dibenzoxazepines; Diphenhydramine; Drug Therapy, Combination;

1986