cimetidine has been researched along with Stomatitis, Aphthous in 13 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Stomatitis, Aphthous: A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study showed that both drug regimens are significantly effective in preventing febrile attacks in PFAPA syndrome, and the presence of a MEFV gene mutation might not be the only significant risk factor for a response to colchicine." | 9.51 | Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations. ( Asna Ashari, K; Mousavi T, M; Raeeskarami, SR; Sadeghi, P; Vahedi, M; Ziaee, V, 2022) |
| "Cimetidine, as an immunomodulating agent, appears to be beneficial in the in-depth treatment of (P)FAPA syndrome." | 7.70 | [(P)FAPA syndrome: value of cimetidine]. ( Ansoborlo, S; Carrère, A; Guillard, JM; Perel, Y; Pillet, P, 2000) |
| "This study showed that both drug regimens are significantly effective in preventing febrile attacks in PFAPA syndrome, and the presence of a MEFV gene mutation might not be the only significant risk factor for a response to colchicine." | 5.51 | Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations. ( Asna Ashari, K; Mousavi T, M; Raeeskarami, SR; Sadeghi, P; Vahedi, M; Ziaee, V, 2022) |
| "The use of antibiotics and cimetidine in PFAPA syndrome are ineffective." | 4.86 | PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment. ( Athanasopoulos, I; Houlakis, M; Koudoumnakis, E; Parpounas, K; Peridis, S; Pilgrim, G, 2010) |
| "Cimetidine, as an immunomodulating agent, appears to be beneficial in the in-depth treatment of (P)FAPA syndrome." | 3.70 | [(P)FAPA syndrome: value of cimetidine]. ( Ansoborlo, S; Carrère, A; Guillard, JM; Perel, Y; Pillet, P, 2000) |
| "Cimetidine therapy was associated with the resolution of the fevers in 7/26 (27%) patients; tonsillectomy was associated with the resolution of the fevers in 11/11 (100%) patients." | 2.46 | A clinical review of 105 patients with PFAPA (a periodic fever syndrome). ( Feder, HM; Salazar, JC, 2010) |
| "PFAPA or Marshall's syndrome is characterized by abrupt onset of periodic episodes of high fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis, often associated with headache and / or abdominal or joint pain." | 2.44 | Oral aphthous-like lesions, PFAPA syndrome: a review. ( Buonaiuto, C; Cirillo, N; Femiano, F; Gombos, F; Lanza, A, 2008) |
| "Pharyngitis is the most frequent symptom associated with fever." | 1.72 | Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome: Clinical characteristics and treatment outcomes - a single center study in Japan. ( Kawano, Y; Ohnishi, T; Sato, S; Suganuma, E; Uejima, Y, 2022) |
| " If an underlying problem requires long-term immunosuppressive medication, it is wiser to choose cimetidine rather than increasing the steroid dosage to resolve atypical PFAPA." | 1.30 | PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis). ( Chen, LC; Huang, JL; Lee, KF; Lee, WI; Lin, SJ; Yang, MH; Yeh, KW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Raeeskarami, SR | 1 |
| Sadeghi, P | 1 |
| Vahedi, M | 1 |
| Asna Ashari, K | 1 |
| Mousavi T, M | 1 |
| Ziaee, V | 1 |
| Ohnishi, T | 1 |
| Sato, S | 1 |
| Uejima, Y | 1 |
| Kawano, Y | 1 |
| Suganuma, E | 1 |
| Amarilyo, G | 1 |
| Rothman, D | 1 |
| Manthiram, K | 1 |
| Edwards, KM | 1 |
| Li, SC | 1 |
| Marshall, GS | 1 |
| Yildirim-Toruner, C | 1 |
| Haines, K | 1 |
| Ferguson, PJ | 1 |
| Lionetti, G | 1 |
| Cherian, J | 1 |
| Zhao, Y | 1 |
| DeLaMora, P | 1 |
| Syverson, G | 1 |
| Nativ, S | 1 |
| Twilt, M | 1 |
| Michelow, IC | 1 |
| Stepanovskiy, Y | 1 |
| Thatayatikom, A | 1 |
| Harel, L | 1 |
| Akoghlanian, S | 1 |
| Tucker, L | 1 |
| Marques, MC | 1 |
| Srinivasalu, H | 1 |
| Propst, EJ | 1 |
| Licameli, GR | 1 |
| Dedeoglu, F | 1 |
| Lapidus, S | 1 |
| Kutsuna, S | 1 |
| Ohmagari, N | 1 |
| Tanizaki, R | 1 |
| Hagino, N | 1 |
| Nishikomori, R | 1 |
| Ujiie, M | 1 |
| Takeshita, N | 1 |
| Hayakawa, K | 1 |
| Kato, Y | 1 |
| Kanagawa, S | 1 |
| Feder, HM | 2 |
| Salazar, JC | 1 |
| Bharti, B | 1 |
| Bharti, S | 1 |
| Peridis, S | 1 |
| Pilgrim, G | 1 |
| Koudoumnakis, E | 1 |
| Athanasopoulos, I | 1 |
| Houlakis, M | 1 |
| Parpounas, K | 1 |
| Pinto, A | 1 |
| Lindemeyer, RG | 1 |
| Sollecito, TP | 1 |
| Kolokotronis, A | 1 |
| Markopoulos, A | 1 |
| Voutas, S | 1 |
| Mataftsi, A | 1 |
| Ikonomidis, P | 1 |
| Antoniades, D | 1 |
| Schorderet, DF | 1 |
| Femiano, F | 1 |
| Lanza, A | 1 |
| Buonaiuto, C | 1 |
| Gombos, F | 1 |
| Cirillo, N | 1 |
| Pillet, P | 1 |
| Ansoborlo, S | 1 |
| Carrère, A | 1 |
| Perel, Y | 1 |
| Guillard, JM | 1 |
| Lee, WI | 1 |
| Yang, MH | 1 |
| Lee, KF | 1 |
| Chen, LC | 1 |
| Lin, SJ | 1 |
| Yeh, KW | 1 |
| Huang, JL | 1 |
4 reviews available for cimetidine and Stomatitis, Aphthous
| Article | Year |
|---|---|
A clinical review of 105 patients with PFAPA (a periodic fever syndrome).
Topics: Child, Preschool; Cimetidine; Female; Fever; Histamine H2 Antagonists; Humans; Lymphadenitis; Male; | 2010 |
PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment.
Topics: Adenoidectomy; Anti-Bacterial Agents; Child; Cimetidine; Fever; Glucocorticoids; Histamine H2 Antago | 2010 |
The PFAPA syndrome in oral medicine: differential diagnosis and treatment.
Topics: Analgesics; Anti-Inflammatory Agents; Child; Child, Preschool; Cimetidine; Diagnosis, Differential; | 2006 |
Oral aphthous-like lesions, PFAPA syndrome: a review.
Topics: Child; Cimetidine; Cytokines; Diagnosis, Differential; Fever; Histamine H2 Antagonists; Humans; Lymp | 2008 |
1 trial available for cimetidine and Stomatitis, Aphthous
| Article | Year |
|---|---|
Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations.
Topics: Child; Cimetidine; Colchicine; Fever; Humans; Lymphadenitis; Lymphadenopathy; Mutation; Pharyngitis; | 2022 |
8 other studies available for cimetidine and Stomatitis, Aphthous
| Article | Year |
|---|---|
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome: Clinical characteristics and treatment outcomes - a single center study in Japan.
Topics: Child; Cimetidine; Colchicine; Female; Fever; Humans; Infant, Newborn; Japan; Lymphadenitis; Lymphad | 2022 |
Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group.
Topics: Adrenal Cortex Hormones; Advisory Committees; Antipyretics; Child; Child, Preschool; Cimetidine; Col | 2020 |
The first case of adult-onset PFAPA syndrome in Japan.
Topics: Adult; Cimetidine; Cytoskeletal Proteins; Female; Fever; Glucocorticoids; Heterozygote; Humans; Japa | 2016 |
Randomized trial of adenotonsillectomy versus expectant treatment in PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome: is the impasse over?
Topics: Administration, Oral; Child; Cimetidine; Fever of Unknown Origin; Follow-Up Studies; Glucocorticoids | 2010 |
Conjunctivitis as a sign of PFAPA syndrome.
Topics: Abdominal Pain; Child; Cimetidine; Conjunctivitis; Fever; Histamine H2 Antagonists; Humans; Lymphade | 2007 |
[(P)FAPA syndrome: value of cimetidine].
Topics: Child; Child, Preschool; Cimetidine; Enzyme Inhibitors; Female; Fever; Humans; Infant; Lymphadenitis | 2000 |
PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis).
Topics: Azathioprine; Child; Cimetidine; Fever; Humans; Immunosuppressive Agents; Infant; Lymphadenitis; Mal | 1999 |
Cimetidine treatment for periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis.
Topics: Adolescent; Child; Child, Preschool; Cimetidine; Fever; Humans; Lymphadenitis; Male; Periodicity; Ph | 1992 |