Page last updated: 2024-10-25

cimetidine and Stomach Neoplasms

cimetidine has been researched along with Stomach Neoplasms in 141 studies

Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.

Stomach Neoplasms: Tumors or cancer of the STOMACH.

Research Excerpts

ExcerptRelevanceReference
"The incidence of gastric cancer was investigated in the cohort of persons who used cimetidine in 1977-81."5.28Use of cimetidine and other peptic ulcer drugs in Denmark 1977-1990 with analysis of the risk of gastric cancer among cimetidine users. ( Mosbech, J; Møller, H; Nissen, A, 1992)
"Cimetidine was administered for 1 year and the histological features of the gastric mucosa were studied to determine if cimetidine induced greater than normal proliferative or metaplastic changes or atypia."5.27The effect of cimetidine on chronic gastric ulcers in rats. ( Deane, SA; Grierson, JM, 1988)
" We divided gastric cancer and the colorectal cancer patients, who performed chemotherapy, into two groups of cimetidine administrated group and a non-administration group, and reviewed whether cimetidine inhibited an expression of E-selectin on vascular endothelial cells by measuring E-selectin in plasma."5.11[An interesting change of E-selectin in cimetidine administration during anticancer drug use]. ( Imaeda, Y; Kawase, J; Kobayashi, K; Matsumoto, S; Umemoto, S, 2005)
"There is little information on the natural history of refractory gastric ulcer, defined as non-healing on cimetidine > or = 1 g daily given for at least 3 months."5.08The management of refractory gastric ulcer using H2-receptor antagonists. ( Bardhan, KD; Beresford, J; Raju, GS; Royston, C, 1996)
"The value of cimetidine in treatment of duodenal ulcer and the Zollinger-Ellison syndrome appears to be well established."4.76A consideration of the adverse effects of cimetidine. ( McGuigan, JE, 1981)
"The effects of combined administration of cimetidine and tetragastrin on gastric acid secretion, the labeling index of the gastric mucosa, and the incidence of gastric adenocarcinomas induced by N-methyl-N'-nitro-N-nitrosoguanidine were investigated in inbred Wistar rats."3.67Effect of cimetidine on inhibition by tetragastrin of carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats. ( Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M; Yamamoto, R; Yamamura, H, 1988)
"Cimetidine is thought to inhibit suppressor T-lymphocyte function and preliminary evidence from a randomized trial indicated that it might prolong survival for patients with operable and inoperable gastric cancer."2.69Prospective, double-blind, placebo-controlled randomized trial of cimetidine in gastric cancer. British Stomach Cancer Group. ( Burton, A; Dunn, JA; Fielding, JW; Hallissey, MT; Kerr, DJ; Langman, MJ; Whiting, JL, 1999)
"Cimetidine 50 mg/kg was injected intravenously into 12 patients immediately prior to IPHP."2.67Metabolic changes in cimetidine treatment for scald injury on the peritoneo-serosal surface in far-advanced gastric cancer patients treated by intraperitoneal hyperthermic perfusion. ( Fujimoto, S; Kiuchi, S; Kobayashi, K; Kokubun, M; Konno, C; Shrestha, RD; Takahashi, M, 1993)
" Immediately after operation (or the decision not to operate) 181 patients were subdivided at random to treatment with a placebo or cimetidine in a dosage of 400 mg twice daily for two years or until death."2.66[Cimetidine treatment of stomach cancer]. ( Bülow, S; Damm, P; Fischerman, K; Hesselfeldt, P; Hjortrup, A; Knigge, UP; Pedersen, IK; Pedersen, VM; Siemssen, OJ; Tønnesen, H, 1989)
"Cimetidine has been shown to have anti-metastatic activity and improves the survival of patients with colorectal cancer."1.37Cimetidine inhibits the adhesion of gastric cancer cells expressing high levels of sialyl Lewis x in human vascular endothelial cells by blocking E-selectin expression. ( Jiang, CG; Li, F; Li, JB; Li, YS; Liu, FR, 2011)
"The exposure of gastric cancer cells to cimetidine resulted in growth inhibition and the induction of apoptosis in a dose-dependent manner."1.36Cimetidine induces apoptosis in gastric cancer cells in vitro and inhibits tumor growth in vivo. ( Jiang, CG; Li, JB; Liu, FR; Xu, HM; Yu, M, 2010)
"Human gastric cancer cells of the line SGC-790 were cultured."1.33[Effects of cimetidine on the biological behaviors of human gastric cancer cells]. ( Gao, J; Jiang, CG; Liu, FR; Wu, T; Xu, HM, 2006)
"Giant gastric ulcer is uncommon."1.30Giant gastric ulcer: its natural history and outcome in the H2RA era. ( Bardhan, KD; Beresford, J; Raju, GS; Royston, C, 1999)
"Subjects with gastric cancer showed significantly higher levels of suppressor lymphocyte activity than normal controls."1.29Comparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients. ( Hahm, KB; Kang, JK; Kim, WH; Lee, SI; Park, IS, 1995)
"The risk of gastric cancer after vagotomy for benign gastric and duodenal disease was examined in a population based cohort of 7198 patients operated on during 1971-79 and followed up until 1988."1.29Gastric cancer risk after vagotomy. ( Ekbom, A; Lundegårdh, G; McLaughlin, JK; Nyrén, O, 1994)
"The incidence of gastric cancer was investigated in the cohort of persons who used cimetidine in 1977-81."1.28Use of cimetidine and other peptic ulcer drugs in Denmark 1977-1990 with analysis of the risk of gastric cancer among cimetidine users. ( Mosbech, J; Møller, H; Nissen, A, 1992)
" Most of the early excess in mortality was attributable to cimetidine being given in the late stages of many diseases, often to counter adverse gastric effects of other drugs."1.28Postmarketing surveillance of the safety of cimetidine: 10 year mortality report. ( Colin-Jones, DG; Langman, MJ; Lawson, DH; Logan, RF; Paterson, KR; Vessey, MP, 1992)
"Only six patients presented with early gastric cancers."1.28Post-cimetidine surveillance for up to ten years: incidence of carcinoma of the stomach and oesophagus. ( Colin-Jones, DG; Langman, MJ; Lawson, DH; Logan, RF; Paterson, KR; Vessey, MP, 1991)
"Five of 99 cases of gastric cancer were exposed to cimetidine at least two years before diagnosis, whereas nine of 365 controls (selected from among users of the Group Health Cooperative pharmacy, matched on age, sex, and first year of pharmacy use) were similarly exposed."1.28Cimetidine use and gastric cancer. ( Feld, AD; Jick, H; Jick, SS; Schumacher, MC, 1990)
"An excess risk for gastric cancer was observed, with a relative risk of about 10 in the first year after beginning use of the drug, which decreased thereafter."1.28Cancer occurrence in a cohort of patients treated with cimetidine. ( Klefter, R; Lindvig, K; Mosbech, J; Møller Jensen, O; Møller, H, 1989)
" So far as can be assessed, however, none of these drug-disease associations represented adverse effects of cimetidine treatment; on the contrary, they resulted from cimetidine being used, knowingly or unknowingly, for treating the symptoms of various diseases or for alleviating adverse effects of other agents such as corticosteroids, non-steroidal anti-inflammatory drugs, and radiotherapy."1.27Postmarketing surveillance of the safety of cimetidine: 12 month mortality report. ( Colin-Jones, DG; Langman, MJ; Lawson, DH; Vessey, MP, 1983)
"Fundic argyrophil carcinoid tumors developed in the course of a 5-year continuous treatment with high dosages of H2-antagonists in a well-documented case of Zollinger-Ellison syndrome with primary hyperparathyroidism, high basal acid output, and serum gastrin."1.27Development of gastric argyrophil carcinoid tumors in a case of Zollinger-Ellison syndrome with primary hyperparathyroidism during long-term antisecretory treatment. ( Bonfils, S; Bonnefond, A; Labeille, D; Lehy, T; Mignon, M; Ruszniewski, P, 1987)
"Cimetidine was administered for 1 year and the histological features of the gastric mucosa were studied to determine if cimetidine induced greater than normal proliferative or metaplastic changes or atypia."1.27The effect of cimetidine on chronic gastric ulcers in rats. ( Deane, SA; Grierson, JM, 1988)
"A case of gastric cancer occurring seven years after a highly selective vagotomy is described."1.27Gastric cancer following highly selective vagotomy. ( Houghton, PW; Leaper, DJ, 1987)
"There have been recent findings of gastric cancer in patients treated with cimetidine but too soon after treatment for that drug to have had a pathogenetic role."1.27The risk of gastric dysplasia in medical long-term treatment of peptic ulcer disease. ( Cardin, F; Di Mario, F; Farinati, F, 1985)
"Seventy-four cases of gastric cancer were identified in those taking cimetidine, but 23 of these were diagnosed before the use of the drug and 29 others with advanced malignancy had received cimetidine within the previous six months only."1.26Cimetidine and gastric cancer: preliminary report from post-marketing surveillance study. ( Colin-Jones, DG; Langman, MJ; Lawson, DH; Vessey, MP, 1982)
"Cimetidine has now been on the market for over three years and appears to be safe and effective."1.26Cimetidine: clinical uses and possible side effects. ( Babb, RR, 1980)
"Cimetidine is a histamine H2-antagonist."1.26No evidence of carcinogenicity of N-nitrosocimetidine in rats. ( Eisenbrand, G; Habs, H; Habs, M; Schmähl, D, 1982)
"The frequency of stomach cancer could not be related to occupational exposure."1.26[Carcinogenesis of gastric cancer with special reference to etiological aspects (author's transl)]. ( Schmähl, D, 1981)

Research

Studies (141)

TimeframeStudies, this research(%)All Research%
pre-1990108 (76.60)18.7374
1990's25 (17.73)18.2507
2000's6 (4.26)29.6817
2010's2 (1.42)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Zan, G1
Zappulli, V1
Cavicchioli, L1
Di Martino, L1
Ros, E1
Conforto, G1
Castagnaro, M1
Jiang, CG3
Liu, FR3
Yu, M1
Li, JB2
Xu, HM2
Li, YS1
Li, F1
Lin, CY1
Bai, DJ1
Yuan, HY1
Wang, K1
Yang, GL1
Hu, MB1
Wu, ZQ1
Li, Y1
Kawase, J1
Kobayashi, K3
Imaeda, Y1
Umemoto, S1
Matsumoto, S1
Wu, T1
Gao, J1
Uedo, N1
Takeuchi, Y1
Yamada, T1
Ishihara, R1
Ogiyama, H1
Yamamoto, S2
Kato, M1
Tatsumi, K1
Masuda, E1
Tamai, C1
Higashino, K1
Iishi, H3
Tatsuta, M3
Hawker, PC1
Muscroft, TJ2
Keighley, MR2
Stoddard, CJ1
Smith, JA1
Johnson, AG2
Clémençon, GH1
Youngs, DJ1
Burdon, DW1
Weisburger, JH1
Arabehety, AR1
Brimblecombe, R1
Scotcher, S1
Sikora, K1
Freedman, L1
Reed, PI2
Haines, K1
Walters, CL4
Smith, SL1
House, FR1
Brimblecomble, RW1
Demling, L1
Thomas, JM1
Misiewicz, G1
Archambault, A1
Levine, JB1
Streett, CS2
Cimprich, RE1
Robertson, JL2
Raptopoulou-Gigi, M1
Boura, P1
Valcanos, N1
Goulis, G1
Wormsley, KG1
Mirvish, SS1
Duan, ZB1
Ware, J1
Baxter, J1
Colin-Jones, DG4
Langman, MJ8
Lawson, DH4
Vessey, MP4
Brühlmann, W1
von Büren, U1
Zollikofer, C1
Müller-Lissner, S1
Blum, A1
Porter, JB1
Janeway, CM1
Hunter, JR1
Perera, DR2
Stergachis, A1
Jick, H3
Dreghorn, CR1
Moffat, LE1
Sulochana, G3
Balakrishnan, K1
Padmanabhan, L3
Rama, KV1
Panchanathan, TB1
Bartsch, H1
Ohshima, H1
Muñoz, N1
Crespi, M1
Cassale, V1
Ramazotti, V1
Lambert, R1
Minaire, Y1
Forichon, J1
Edge, D1
Eastwood, GL1
Quimby, GF1
Rodrigo Rodríguez, M1
González San Martín, P1
Alonso Antón, P1
de Portugal Alvarez, J1
Kalavathy, R1
Lijinsky, W1
Reuber, MD1
Freston, JW1
Downing, R1
Black, J1
Poleski, MH1
Rodríguez, S1
Moreno Otero, R1
Mearin Manrique, F1
Pajares García, JM1
Babb, RR1
McGuigan, JE1
Soulé, JC1
Delchier, JC1
Morin, T1
Bader, JP1
Michowicz, A1
Grzegorczyk, K1
Sadagopan, T1
Lewis, JH1
Woods, M1
von Günter Lambrecht, B1
Bendall, MJ1
Sainsbury, R1
Graham, JR1
Habs, M1
Eisenbrand, G1
Habs, H1
Schmähl, D2
Bartholomew, BA1
Hill, MJ2
Hudson, MJ1
Ruddell, WS2
Taylor, TV3
Lee, D2
Howatson, AG2
Anderson, J2
Macleod, IB2
Piper, DW1
Henry, DA1
Festen, HP1
Kennedy, T1
Green, WE1
Kjaergaard, J1
Stadil, F1
Wulff, HR1
Knigge, U2
Dejgård, A1
Christiansen, PM1
Crean, GP2
Morson, BC1
Leslie, GB2
Roe, FJ3
Arima, N3
Kinoshita, Y2
Nakamura, A3
Yamashita, Y3
Chiba, T3
Hahm, KB1
Kim, WH1
Lee, SI1
Kang, JK1
Park, IS1
Wen, QS1
Zhang, GZ1
Kong, XT1
Lundegårdh, G1
Ekbom, A1
McLaughlin, JK1
Nyrén, O1
Watson, SA1
Wilkinson, LJ1
Robertson, JF1
Hardcastle, JD2
Fujimoto, S2
Takahashi, M2
Kokubun, M2
Shrestha, RD2
Kiuchi, S2
Konno, C2
Gold, JE1
Malamud, SC1
LaRosa, F1
Osband, ME1
Overgaard, H1
Timshel, S1
Raju, GS2
Bardhan, KD2
Royston, C2
Beresford, J2
Walker, AM1
Jick, SS2
Edwardes, MD1
Baltzan, M1
Shapiro, S1
Porta, M1
Hortemo, GS1
Maartmann-Moe, H1
Rökke, O1
Viste, A1
Dunn, JA1
Whiting, JL1
Burton, A1
Hallissey, MT1
Fielding, JW1
Kerr, DJ1
La Vecchia, C1
Tavani, A1
Taylor, RH1
Menzies-Gow, N1
Lovell, D1
La Brooy, SJ1
Misiewicz, JJ1
Elder, JB2
Ganguli, PC2
Gillespie, IE2
Cassell, PG1
Guslandi, M1
Mullen, PW1
Buck, JP1
Murgatroyd, RE1
Boylston, AW1
Baron, JH1
Feurle, GE1
Welch, CE1
Malt, RA1
Saegesser, F1
Elliott, J1
de las Casas Alonso, P1
González Hermoso, F1
García Santos, J1
Marrero García, N1
Martín Herrera, A1
Núñez Díaz, V1
Rodríguez Torres, J1
Soler Arocha, A1
Borchgrevink, CE1
Vennerøod, AM1
Keel, HJ1
Lämmli, J1
Arnot, RS1
Møller, H2
Nissen, A1
Mosbech, J2
Logan, RF2
Paterson, KR2
Nakata, H2
Morishita, T1
Fujita, T1
Ohta, M1
Isobe, Y1
Nagai, H1
Muramatsu, M1
Aihara, H1
Otomo, S1
Schumacher, MC1
Feld, AD1
Klimczak, J1
Mignon, M1
Lehy, T1
Bonnefond, A1
Ruszniewski, P1
Labeille, D1
Bonfils, S1
Lindvig, K1
Klefter, R1
Møller Jensen, O1
Tønnesen, H2
Knigge, UP1
Bülow, S2
Damm, P2
Fischerman, K2
Hesselfeldt, P2
Hjortrup, A2
Pedersen, IK2
Pedersen, VM2
Siemssen, OJ2
Stockbruegger, RW1
Emami, S2
Gespach, C2
Bodéré, H1
Morris, DL1
Ubhi, CS1
Ansell, ID1
Wiernik, PH1
Schwartz, EL1
Strauman, JJ1
Dutcher, JP1
Lipton, RB1
Paietta, E1
Amland, PF1
Svane, S1
Crissman, JW1
Kurosu, Y1
Tanaka, N1
Furusho, Y1
Morita, K1
Baba, M2
Mikuni, T1
Taniguchi, H2
Boom, SJ1
Blower, AL1
McMahon, RF1
Lawler, W1
Yamamura, H1
Yamamoto, R1
Loffeld, RJ1
Loffeld, BC1
Arends, JW1
Flendrig, JA1
van Spreeuwel, JP1
Deane, SA1
Grierson, JM1
Mikulin, T1
Varas Lorenzo, MJ1
Strauchen, JA1
Moran, C1
Goldsmith, M1
Greenberg, M1
Stockley, I1
Kiff, ES1
Houghton, PW1
Leaper, DJ1
Cheret, AM1
Laboisse, CL1
Roumagnac, I1
Augeron, C1
Lewin, MJ1
Di Mario, F1
Farinati, F1
Cardin, F1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Impact of Second-look Endoscopy After Endoscopic Submucosal Dissection of Gastric Neoplasm[NCT02005809]Phase 3268 participants (Anticipated)Interventional2013-03-31Recruiting
Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534]29 participants (Actual)Observational2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for cimetidine and Stomach Neoplasms

ArticleYear
[Conservative therapy of peptic ulcer].
    Schweizerische medizinische Wochenschrift, 1980, Oct-11, Volume: 110, Issue:41

    Topics: Antacids; Benzodiazepinones; Carbenoxolone; Cimetidine; Gastric Acid; Gastroscopy; Histamine H2 Anta

1980
[Adverse effects of H2 blockaders].
    Acta gastroenterologica Latinoamericana, 1980, Volume: 10, Issue:4

    Topics: Breast Diseases; Cimetidine; Duodenal Ulcer; Gastric Acid; Guanidines; Heart Rate; Histamine H2 Anta

1980
Histamine H2-receptor antagonists in the short- and long-term treatment of duodenal ulcer.
    Clinics in gastroenterology, 1984, Volume: 13, Issue:2

    Topics: Alcohol Drinking; Androgen Antagonists; Anti-Ulcer Agents; Bone Marrow; Cimetidine; Clinical Trials

1984
Pharmacologic options for the control of peptic ulcer disease.
    Advances in internal medicine, 1984, Volume: 30

    Topics: Antacids; Anti-Ulcer Agents; Benzimidazoles; Bismuth; Carbenoxolone; Cimetidine; Duodenal Ulcer; His

1984
Long-term treatment of duodenal ulcer.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Jun-23, Volume: 65, Issue:25

    Topics: Cimetidine; Costs and Cost Analysis; Duodenal Ulcer; Humans; Postoperative Complications; Ranitidine

1984
The etiology of gastric cancer. Intragastric nitrosamide formation and other theories.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:3

    Topics: Animals; Cimetidine; Diet; Dietary Carbohydrates; Gastric Mucosa; Humans; Japan; Life Style; Nitrate

1983
[Adverse reactions to cimetidine].
    Zhonghua nei ke za zhi, 1984, Volume: 23, Issue:8

    Topics: Blood; Breast; Central Nervous System; Cimetidine; Drug Interactions; Humans; Immunity; Kidney; Live

1984
Cimetidine: II. Adverse reactions and patterns of use.
    Annals of internal medicine, 1982, Volume: 97, Issue:5

    Topics: Cardiovascular Diseases; Central Nervous System Diseases; Chemical and Drug Induced Liver Injury; Ci

1982
A consideration of the adverse effects of cimetidine.
    Gastroenterology, 1981, Volume: 80, Issue:1

    Topics: Agranulocytosis; Animals; Bone Marrow; Central Nervous System; Chemical and Drug Induced Liver Injur

1981
[Maintenance cimetidine treatment in duodenal ulcer disease. Second part: Side-effects and indications (author's transl)].
    Gastroenterologie clinique et biologique, 1980, Volume: 4, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; Cimetidine; Confusion; Dogs;

1980
[Undesirable effects of the use of cimetidine].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1981, Oct-01, Volume: 34, Issue:19

    Topics: Aged; Carcinogens; Cerebrovascular Disorders; Cimetidine; Female; Gastritis; Guanidines; Humans; Mal

1981
A review of epidemiological studies on cancer in relation to the use of anti-ulcer drugs.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2002, Volume: 11, Issue:2

    Topics: Case-Control Studies; Cimetidine; Clinical Trials as Topic; Female; Histamine H2 Antagonists; Humans

2002
[Gastrointestinal hormones. Current knowledge].
    Medizinische Klinik, 1979, Feb-02, Volume: 74, Issue:5

    Topics: Bombesin; Cholecystokinin; Cimetidine; Epidermal Growth Factor; Gastric Inhibitory Polypeptide; Gast

1979
Abdominal surgery (first of three parts).
    The New England journal of medicine, 1979, Mar-22, Volume: 300, Issue:12

    Topics: Abdomen; Aged; Appendicitis; Cimetidine; Crohn Disease; Duodenal Ulcer; Gastrectomy; Gastroesophagea

1979

Trials

14 trials available for cimetidine and Stomach Neoplasms

ArticleYear
Perioperative cimetidine administration promotes peripheral blood lymphocytes and tumor infiltrating lymphocytes in patients with gastrointestinal cancer: Results of a randomized controlled clinical trial.
    World journal of gastroenterology, 2004, Volume: 10, Issue:1

    Topics: Adjuvants, Immunologic; Adult; Aged; B-Lymphocytes; Cimetidine; Colorectal Neoplasms; Female; Humans

2004
[An interesting change of E-selectin in cimetidine administration during anticancer drug use].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:11

    Topics: Cimetidine; Colorectal Neoplasms; E-Selectin; Endothelial Cells; Humans; Neoplastic Cells, Circulati

2005
Effect of a proton pump inhibitor or an H2-receptor antagonist on prevention of bleeding from ulcer after endoscopic submucosal dissection of early gastric cancer: a prospective randomized controlled trial.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Cimetidi

2007
Cimetidine is unlikely to increase formation of intragastric N-nitroso-compounds in patients taking a normal diet.
    Lancet (London, England), 1981, Feb-21, Volume: 1, Issue:8217

    Topics: Bacteria; Cimetidine; Fasting; Gastric Mucosa; Guanidines; Humans; Hydrogen-Ion Concentration; Male;

1981
Histamine H2-receptor antagonists in the short- and long-term treatment of duodenal ulcer.
    Clinics in gastroenterology, 1984, Volume: 13, Issue:2

    Topics: Alcohol Drinking; Androgen Antagonists; Anti-Ulcer Agents; Bone Marrow; Cimetidine; Clinical Trials

1984
[Gastric secretory inhibitors improve the visibility of gastric mucosal detail in barium studies of the stomach: a controlled clinical trial (author's transl)].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1981, Volume: 134, Issue:6

    Topics: Benzodiazepinones; Cimetidine; Depression, Chemical; Gastric Emptying; Gastric Juice; Guanidines; Hu

1981
[Modulation effect of cimetidine on the production of IL-2 and interferon-gamma in patients with gastric cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1994, Volume: 16, Issue:4

    Topics: Adjuvants, Immunologic; Adult; Aged; Cimetidine; Female; Humans; Interferon-gamma; Interleukin-2; Le

1994
Metabolic changes in cimetidine treatment for scald injury on the peritoneo-serosal surface in far-advanced gastric cancer patients treated by intraperitoneal hyperthermic perfusion.
    Surgery today, 1993, Volume: 23, Issue:5

    Topics: Blood Pressure; Burns; Chemotherapy, Cancer, Regional Perfusion; Cimetidine; Combined Modality Thera

1993
The management of refractory gastric ulcer using H2-receptor antagonists.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:3

    Topics: Adult; Anti-Ulcer Agents; Cimetidine; Drug Resistance; Female; Gastric Mucosa; Gastroscopy; Histamin

1996
Confounding by indication?
    Epidemiology (Cambridge, Mass.), 1997, Volume: 8, Issue:1

    Topics: Cimetidine; Confounding Factors, Epidemiologic; Histamine H2 Antagonists; Humans; Ranitidine; Stomac

1997
Prospective, double-blind, placebo-controlled randomized trial of cimetidine in gastric cancer. British Stomach Cancer Group.
    British journal of cancer, 1999, Volume: 81, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Cimetidine; Double-Blind Method; Female; Histamine H2 Antagonists; H

1999
[Cimetidine treatment of stomach cancer].
    Ugeskrift for laeger, 1989, Jun-12, Volume: 151, Issue:24

    Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle

1989
Bacterial overgrowth as a consequence of reduced gastric acidity.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 111

    Topics: Achlorhydria; Aged; Anemia, Pernicious; Bacteria; Benzodiazepinones; Cimetidine; Clinical Trials as

1985
Effect of cimetidine on survival after gastric cancer.
    Lancet (London, England), 1988, Oct-29, Volume: 2, Issue:8618

    Topics: Actuarial Analysis; Adult; Aged; Aged, 80 and over; Cimetidine; Clinical Trials as Topic; Denmark; D

1988

Other Studies

114 other studies available for cimetidine and Stomach Neoplasms

ArticleYear
Gastric B-cell lymphoma with Mott cell differentiation in a dog.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2009, Volume: 21, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Cell Differentiation; Cimetidine; Dog Diseases; Dogs; Euthanasia; Gastro

2009
Cimetidine induces apoptosis in gastric cancer cells in vitro and inhibits tumor growth in vivo.
    Oncology reports, 2010, Volume: 23, Issue:3

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Proliferation; Cimetidine; Do

2010
Cimetidine inhibits the adhesion of gastric cancer cells expressing high levels of sialyl Lewis x in human vascular endothelial cells by blocking E-selectin expression.
    International journal of molecular medicine, 2011, Volume: 27, Issue:4

    Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cimetidine; E-Selectin; Endothelial Ce

2011
[Effects of cimetidine on the biological behaviors of human gastric cancer cells].
    Zhonghua yi xue za zhi, 2006, Jul-11, Volume: 86, Issue:26

    Topics: Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cimetidine; Extracellular Matrix; Hu

2006
Gastric cancer after cimetidine in patient with two negative pre-treatment biopsies.
    Lancet (London, England), 1980, Mar-29, Volume: 1, Issue:8170

    Topics: Aged; Bacteria; Cimetidine; Female; Guanidines; Humans; Nitrosamines; Stomach; Stomach Neoplasms; St

1980
Cimetidine, delay in diagnosis, and carcinoma of the stomach.
    Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187

    Topics: Age Factors; Aged; Cimetidine; Guanidines; Humans; Male; Middle Aged; Peptic Ulcer; Stomach Neoplasm

1980
Cimetidine, nitroso compounds, and gastric cancer.
    Lancet (London, England), 1981, Jun-13, Volume: 1, Issue:8233

    Topics: Cimetidine; Guanidines; Humans; Nitroso Compounds; Stomach Neoplasms

1981
Cimetidine, nitrosation, and carcinogenicity.
    Lancet (London, England), 1981, Sep-26, Volume: 2, Issue:8248

    Topics: Animals; Cimetidine; Dogs; Guanidines; Humans; Hydrogen-Ion Concentration; Nitroso Compounds; Rats;

1981
Gastric cancer and cimetidine: does delay in diagnosis matter?
    Lancet (London, England), 1981, Sep-19, Volume: 2, Issue:8247

    Topics: Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Prognosis; Stomach Neoplasms; Time

1981
Cimetidine, nitrosation, and cancer.
    Lancet (London, England), 1981, Oct-31, Volume: 2, Issue:8253

    Topics: Adenocarcinoma; Cimetidine; Duodenal Ulcer; Guanidines; Humans; Male; Middle Aged; Nitroso Compounds

1981
Cimetidine, nitrosation, and carcinogenicity.
    Lancet (London, England), 1981, Dec-05, Volume: 2, Issue:8258

    Topics: Cimetidine; Guanidines; Humans; Hydrogen-Ion Concentration; Nitroso Compounds; Stomach Neoplasms

1981
Cimetidine, nitrosation, and carcinogenicity.
    Lancet (London, England), 1982, Feb-13, Volume: 1, Issue:8268

    Topics: Cimetidine; Guanidines; Humans; Hydrogen-Ion Concentration; Nitrites; Nitroso Compounds; Stomach Neo

1982
[Changes in therapy of duodenal ulcers. The European Gastro-Club 1983 discusses new pathophysiologic and epidemiologic data referring to drug and surgical therapy].
    Fortschritte der Medizin, 1983, Dec-15, Volume: 101, Issue:47-48

    Topics: Amino Acids; Benzimidazoles; Carbenoxolone; Cimetidine; Duodenal Ulcer; Gastric Acid; Histamine; His

1983
[H2 receptor antagonists: clinical use].
    L'union medicale du Canada, 1984, Volume: 113, Issue:12

    Topics: Cimetidine; Duodenal Ulcer; Histamine H1 Antagonists; Humans; Ranitidine; Stomach Neoplasms; Stomach

1984
Pathologic findings in the stomachs of rats treated with the H2-receptor antagonist tiotidine.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 101

    Topics: Animals; Atrophy; Cimetidine; Female; Histamine H2 Antagonists; Male; Parietal Cells, Gastric; Pylor

1984
Lymphocyte subpopulations in gastric disease; effect of histamine and cimetidine on immunoregulatory T cell subsets.
    Journal of immunopharmacology, 1984, Volume: 6, Issue:3

    Topics: Cimetidine; Duodenal Ulcer; Gastritis; Histamine; Humans; In Vitro Techniques; Middle Aged; Stomach

1984
Cimetidine and gastric cancer.
    British medical journal (Clinical research ed.), 1983, Jan-08, Volume: 286, Issue:6359

    Topics: Cimetidine; Guanidines; Humans; Stomach Neoplasms

1983
Postmarketing surveillance of the safety of cimetidine: 12 month mortality report.
    British medical journal (Clinical research ed.), 1983, May-28, Volume: 286, Issue:6379

    Topics: Aged; Alcohol Drinking; Cimetidine; Colonic Neoplasms; England; Esophageal Neoplasms; Evaluation Stu

1983
Absence of a causal association between cimetidine and gastric cancer.
    Gastroenterology, 1984, Volume: 87, Issue:4

    Topics: Cimetidine; Epidemiologic Methods; Female; Humans; Male; Middle Aged; Stomach Neoplasms

1984
Changing patterns of gastric surgery in a district general hospital.
    Health bulletin, 1984, Volume: 42, Issue:5

    Topics: Adenocarcinoma; Cimetidine; Female; Hospitals, District; Humans; Male; Peptic Ulcer; Peptic Ulcer Pe

1984
Immunoglobulins in gastric aspirate before & after oral cimetidine in certain gastric lesions in acid secretors.
    The Indian journal of medical research, 1984, Volume: 80

    Topics: Cimetidine; Duodenal Ulcer; Gastric Acidity Determination; Gastric Juice; Humans; Hydrogen-Ion Conce

1984
In-vivo nitrosation, precancerous lesions and cancers of the gastrointestinal tract. On-going studies and preliminary results.
    IARC scientific publications, 1984, Issue:57

    Topics: Anemia, Pernicious; Cimetidine; Gastrectomy; Gastritis, Atrophic; Humans; Nitrosamines; Nitroso Comp

1984
Endoscopy and gastric ulceration before cimetidine.
    The New Zealand medical journal, 1984, Aug-22, Volume: 97, Issue:762

    Topics: Biopsy; Cimetidine; Gastroscopy; Humans; Stomach Neoplasms; Stomach Ulcer

1984
Effect of chronic cimetidine ingestion on fundic and antral epithelial proliferation in the rat.
    Digestive diseases and sciences, 1983, Volume: 28, Issue:1

    Topics: Animals; Cimetidine; Epithelium; Gastric Fundus; Guanidines; Pyloric Antrum; Rats; Rats, Inbred Lew;

1983
Cimetidine and gastric cancer: a reappraisal.
    Drug and therapeutics bulletin, 1983, Aug-26, Volume: 21, Issue:17

    Topics: Cimetidine; Humans; Stomach Neoplasms

1983
[Cimetidine and gastric cancer].
    Medicina clinica, 1983, Sep-24, Volume: 81, Issue:8

    Topics: Adenocarcinoma; Cimetidine; False Negative Reactions; Humans; Lymphoma; Stomach Neoplasms

1983
Protein & aminoacid concentrations in the gastric aspirate in the diagnosis of gastric carcinoma.
    The Indian journal of medical research, 1983, Volume: 78 Suppl

    Topics: Amino Acids; Carcinoma; Cimetidine; Gastric Juice; Humans; Proteins; Stomach Neoplasms

1983
Comparison of nitrosocimetidine with nitrosomethylnitroguanidine in chronic feeding tests in rats.
    Cancer research, 1984, Volume: 44, Issue:2

    Topics: Animals; Cimetidine; Drinking; Female; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred F344; S

1984
Does cimetidine cause gastric cancer?
    British medical journal (Clinical research ed.), 1981, May-09, Volume: 282, Issue:6275

    Topics: Aged; Cimetidine; Guanidines; Humans; Male; Stomach Neoplasms

1981
Does cimetidine cause gastric cancer?
    British medical journal (Clinical research ed.), 1981, Apr-11, Volume: 282, Issue:6271

    Topics: Anemia, Pernicious; Cimetidine; Gastric Acid; Guanidines; Humans; Stomach Neoplasms

1981
Cimetidine and gastric cancer: preliminary report from post-marketing surveillance study.
    British medical journal (Clinical research ed.), 1982, Nov-06, Volume: 285, Issue:6351

    Topics: Adult; Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Product Surveillance, Postma

1982
Cimetidine and gastric carcinoma.
    Annals of internal medicine, 1983, Volume: 98, Issue:5 Pt 1

    Topics: Cimetidine; Duodenal Ulcer; Guanidines; Humans; Recurrence; Stomach Neoplasms

1983
[Cimetidine and stomach cancer: deceptive response and diagnostic delay].
    Medicina clinica, 1983, Mar-12, Volume: 80, Issue:8

    Topics: Adenocarcinoma; Aged; Cimetidine; False Negative Reactions; Female; Guanidines; Humans; Male; Middle

1983
Cimetidine: clinical uses and possible side effects.
    Postgraduate medicine, 1980, Volume: 68, Issue:6

    Topics: Cimetidine; Confusion; Esophagitis, Peptic; Gastrointestinal Hemorrhage; Guanidines; Humans; Male; N

1980
beta-Glucuronidase in gastric aspirate after oral cimetidine in the diagnosis of carcinoma of the stomach.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Feb-26, Volume: 119, Issue:1-2

    Topics: Administration, Oral; Cimetidine; Duodenal Ulcer; Gastric Juice; Glucuronidase; Guanidines; Humans;

1982
Gastric carcinoma in patients with unoperated duodenal ulcer disease.
    The American journal of gastroenterology, 1982, Volume: 77, Issue:6

    Topics: Adenocarcinoma; Cimetidine; Duodenal Ulcer; Female; Humans; Intestinal Polyps; Male; Middle Aged; Pr

1982
[Stomach cancer from cimetidine?].
    Medizinische Monatsschrift fur Pharmazeuten, 1982, Volume: 5, Issue:7

    Topics: Cimetidine; Guanidines; Humans; Stomach Neoplasms

1982
Gastric ulcer healing by cimetidine in non-Hodgkin's lymphoma of the stomach.
    Postgraduate medical journal, 1982, Volume: 58, Issue:680

    Topics: Aged; Cimetidine; Guanidines; Humans; Lymphoma; Male; Stomach Neoplasms; Stomach Ulcer

1982
Gastric pseudolymphoma developing from chronic gastric ulcer: endoscopic diagnosis and the effect of cimetidine.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:11

    Topics: Cimetidine; Endoscopy; Humans; Lymphoma; Male; Middle Aged; Stomach Neoplasms; Stomach Ulcer

1982
No evidence of carcinogenicity of N-nitrosocimetidine in rats.
    Hepato-gastroenterology, 1982, Volume: 29, Issue:6

    Topics: Animals; Cimetidine; Female; Follow-Up Studies; Guanidines; Male; Methylnitronitrosoguanidine; Neopl

1982
Gastric bacteria, nitrate, nitrite and nitrosamines in patients with pernicious anaemia and in patients treated with cimetidine.
    IARC scientific publications, 1980, Issue:31

    Topics: Anemia, Pernicious; Animals; Animals, Newborn; Cimetidine; Gastric Juice; Guanidines; Humans; Hydrog

1980
Gastric cancer and cimetidine.
    Journal of the Royal College of Surgeons of Edinburgh, 1981, Volume: 26, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Peptic Ulcer

1981
Cimetidine and cancer.
    The Medical journal of Australia, 1981, Apr-04, Volume: 1, Issue:7

    Topics: Cimetidine; Guanidines; Humans; Peptic Ulcer; Stomach Neoplasms

1981
Adverse effects of anti-ulcer drugs.
    Drugs, 1981, Volume: 21, Issue:6

    Topics: Antacids; Anti-Ulcer Agents; Carbenoxolone; Carcinogens; Cimetidine; Drug Interactions; Endocrine Gl

1981
[Carcinogenesis of gastric cancer with special reference to etiological aspects (author's transl)].
    Zentralblatt fur Chirurgie, 1981, Volume: 106, Issue:15

    Topics: Age Factors; Cimetidine; Environmental Exposure; Food Additives; Gastrectomy; Humans; Hydrogen-Ion C

1981
[Cimetidine and stomach carcinoma].
    Nederlands tijdschrift voor geneeskunde, 1981, Nov-21, Volume: 125, Issue:47

    Topics: Cimetidine; Gastric Acid; Guanidines; Humans; Nitroso Compounds; Stomach Neoplasms

1981
Stomal and recurrent ulceration: medical or surgical management?
    American journal of surgery, 1980, Volume: 139, Issue:1

    Topics: Cimetidine; Gastrectomy; Guanidines; Humans; Peptic Ulcer; Postoperative Complications; Recurrence;

1980
[Cimetidine (Tagamet) and cancer of the stomach].
    Ugeskrift for laeger, 1980, Aug-04, Volume: 142, Issue:32

    Topics: Cimetidine; Guanidines; Humans; Stomach Neoplasms; Stomach Ulcer

1980
[Cancer of the stomach - and cimetidine].
    Ugeskrift for laeger, 1980, Aug-04, Volume: 142, Issue:32

    Topics: Adenocarcinoma; Aged; Biopsy; Cimetidine; Diagnosis, Differential; Female; Guanidines; Humans; Male;

1980
Cimetidine: further evidence of noncarcinogenicity in dogs.
    The New England journal of medicine, 1981, Mar-12, Volume: 304, Issue:11

    Topics: Animals; Cimetidine; Dogs; Gastric Mucosa; Guanidines; Stomach Neoplasms; Time Factors

1981
Homologous desensitization of histamine H2 receptors in the human gastric carcinoma cell line MKN-45.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cimetidine; Colforsin; Cyclic AMP; Dinoprostone; Dose-Respon

1993
Comparison of immunomodulative effects of the histamine-2 receptor antagonists cimetidine, ranitidine, and famotidine on peripheral blood mononuclear cells in gastric cancer patients.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:3

    Topics: Adjuvants, Immunologic; Case-Control Studies; Cimetidine; Cytotoxicity Tests, Immunologic; Famotidin

1995
Gastric cancer risk after vagotomy.
    Gut, 1994, Volume: 35, Issue:7

    Topics: Aged; Cimetidine; Cohort Studies; Duodenal Diseases; Female; Humans; Male; Medical Record Linkage; M

1994
Effect of histamine on the growth of human gastrointestinal tumours: reversal by cimetidine.
    Gut, 1993, Volume: 34, Issue:8

    Topics: Animals; Cell Division; Cimetidine; Colorectal Neoplasms; Cyclic AMP; Dose-Response Relationship, Dr

1993
Adoptive chemoimmunotherapy using ex vivo activated memory T-cells and cyclophosphamide: tumor lysis syndrome of a metastatic soft tissue sarcoma.
    American journal of hematology, 1993, Volume: 44, Issue:1

    Topics: Aged; Cimetidine; Clinical Protocols; Cyclophosphamide; Humans; Immunologic Memory; Immunotherapy, A

1993
[Late recurrence of stomach cancer in a patient treated with a H2 receptor antagonist].
    Ugeskrift for laeger, 1996, May-06, Volume: 158, Issue:19

    Topics: Adenocarcinoma; Antineoplastic Agents; Cimetidine; Histamine H2 Antagonists; Humans; Male; Middle Ag

1996
Confounding by indication.
    Epidemiology (Cambridge, Mass.), 1996, Volume: 7, Issue:4

    Topics: Cimetidine; Confounding Factors, Epidemiologic; Histamine H2 Antagonists; Humans; Incidence; Ranitid

1996
Histamine-2 receptor antagonists and gastric cancer.
    Epidemiology (Cambridge, Mass.), 1996, Volume: 7, Issue:4

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cimetidine; Female; Histamine H2 Antagonists; Humans;

1996
Confounding by indication, histamine-2 receptor antagonists, and gastric cancer.
    Epidemiology (Cambridge, Mass.), 1997, Volume: 8, Issue:3

    Topics: Cimetidine; Confounding Factors, Epidemiologic; Histamine H2 Antagonists; Humans; Stomach Neoplasms

1997
Confounding by indication and past clinical trials.
    Epidemiology (Cambridge, Mass.), 1997, Volume: 8, Issue:2

    Topics: Anti-Ulcer Agents; Cimetidine; Confounding Factors, Epidemiologic; Humans; Randomized Controlled Tri

1997
Effect of cimetidine on development of gastric cancer in rats after gastrojejunostomy.
    The European journal of surgery = Acta chirurgica, 1999, Volume: 165, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Chi-Square Distribution; Cimetidine; Disease Models, Animal; Drug S

1999
Giant gastric ulcer: its natural history and outcome in the H2RA era.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:12

    Topics: Adult; Aged; Biopsy; Cause of Death; Cimetidine; Female; Follow-Up Studies; Gastric Mucosa; Histamin

1999
Misleading response of malignant gastric ulcers to cimetidine.
    Lancet (London, England), 1978, Apr-01, Volume: 1, Issue:8066

    Topics: Adult; Cell Transformation, Neoplastic; Cimetidine; Diagnosis, Differential; Diagnostic Errors; Fema

1978
Cimetidine and malignant gastric ulcers.
    Lancet (London, England), 1978, May-20, Volume: 1, Issue:8073

    Topics: Adult; Aged; Cimetidine; Diagnosis, Differential; Female; Guanidines; Humans; Lymphoma; Male; Stomac

1978
Cimetidine and gastric cancer.
    Lancet (London, England), 1979, May-12, Volume: 1, Issue:8124

    Topics: Adenocarcinoma; Adult; Aged; Cimetidine; Female; Guanidines; Humans; Male; Middle Aged; Nitroso Comp

1979
Cimetidine and gastric cancer.
    Lancet (London, England), 1979, May-12, Volume: 1, Issue:8124

    Topics: Cimetidine; Gastrectomy; Gastric Mucosa; Guanidines; Humans; Stomach Neoplasms

1979
Cimetidine and gastric cancer.
    Lancet (London, England), 1979, May-12, Volume: 1, Issue:8124

    Topics: Cimetidine; Guanidines; Humans; Nitroso Compounds; Nitrosoguanidines; Stomach Neoplasms

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Adenocarcinoma; Adult; Aged; Cimetidine; Female; Guanidines; Humans; Male; Stomach Neo

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Carcinogens; Cimetidine; Guanidines; Humans; Nitrosamines; Stomach Neoplasms

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Carcinogens; Carcinoma in Situ; Cimetidine; Gastric Juice; Guanidines; Humans; Male; M

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-09, Volume: 1, Issue:8128

    Topics: Achlorhydria; Cimetidine; Gastric Juice; Guanidines; Humans; Nitrosamines; Stomach Neoplasms

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-30, Volume: 1, Issue:8131

    Topics: Cimetidine; Gastric Juice; Guanidines; Humans; Stomach Neoplasms

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Jun-30, Volume: 1, Issue:8131

    Topics: Cimetidine; Dyspepsia; Guanidines; Humans; Stomach Neoplasms

1979
Perforation of gastric carcinoma (at site of previous benign ulcer) after withdrawal of cimetidine.
    Lancet (London, England), 1979, Jul-07, Volume: 2, Issue:8132

    Topics: Adenocarcinoma; Cimetidine; Guanidines; Humans; Male; Middle Aged; Peptic Ulcer Perforation; Stomach

1979
Gastric cancer in patients who have taken cimetidine.
    Lancet (London, England), 1979, Aug-04, Volume: 2, Issue:8136

    Topics: Achlorhydria; Animals; Carcinogens; Cimetidine; Guanidines; Humans; In Vitro Techniques; Methylnitro

1979
Cimetidine and gastric cancer: negative studies in dogs.
    Lancet (London, England), 1979, Oct-13, Volume: 2, Issue:8146

    Topics: Animals; Carcinogens; Cimetidine; Dogs; Female; Guanidines; Male; Stomach Neoplasms; Time Factors

1979
[Abdominal surgery (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Apr-11, Volume: 67, Issue:15

    Topics: Cimetidine; Diverticulum; Gastrointestinal Diseases; Humans; Intestinal Perforation; Peptic Ulcer; S

1978
Side effects of cimetidine use coming under scrutiny.
    JAMA, 1979, Jul-06, Volume: 242, Issue:1

    Topics: Cimetidine; Guanidines; Humans; Male; Peptic Ulcer; Risk; Spermatozoa; Stomach Neoplasms; United Sta

1979
[Healing action of cimetidine in an incipient gastric cancer in its depressive variation. Apropos of a case].
    Revista espanola de las enfermedades del aparato digestivo, 1979, Volume: 56, Issue:3

    Topics: Cimetidine; Gastric Mucosa; Guanidines; Humans; Intestinal Neoplasms; Male; Middle Aged; Neoplasm Me

1979
[Adverse effects of cimetidine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979, Nov-10, Volume: 99, Issue:31

    Topics: Cimetidine; Guanidines; Humans; Stomach Neoplasms; Thrombosis

1979
[Gastroduodenal ulcer disease (author's transl)].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1978, Aug-22, Volume: 67, Issue:34

    Topics: Antacids; Biopsy; Cimetidine; Diagnosis, Differential; Diet Therapy; Gastroscopy; Humans; Peptic Ulc

1978
Drugs for peptic ulcer.
    Journal of the Royal College of Physicians of London, 1979, Volume: 13, Issue:1

    Topics: Antacids; Bismuth; Carbenoxolone; Chelating Agents; Cimetidine; Duodenal Neoplasms; Duodenal Ulcer;

1979
Cimetidine and gastric carcinoma.
    British medical journal, 1977, Oct-15, Volume: 2, Issue:6093

    Topics: Cimetidine; Guanidines; Humans; Middle Aged; Stomach Neoplasms; Stomach Ulcer

1977
Use of cimetidine and other peptic ulcer drugs in Denmark 1977-1990 with analysis of the risk of gastric cancer among cimetidine users.
    Gut, 1992, Volume: 33, Issue:9

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Cimetidine; Cohort Studies; Denmark; Female; Histamine

1992
Postmarketing surveillance of the safety of cimetidine: 10 year mortality report.
    Gut, 1992, Volume: 33, Issue:9

    Topics: Cimetidine; Duodenal Neoplasms; Esophageal Neoplasms; Female; Histamine H2 Antagonists; Humans; Live

1992
Post-cimetidine surveillance for up to ten years: incidence of carcinoma of the stomach and oesophagus.
    The Quarterly journal of medicine, 1991, Volume: 78, Issue:285

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cimetidine; Cohort Studies; Esoph

1991
Presence of histamine H2-receptors on human gastric carcinoma cell line MKN-45 and their increase by retinoic acid treatment.
    Biochemical and biophysical research communications, 1991, May-15, Volume: 176, Issue:3

    Topics: Binding, Competitive; Cell Line; Cimetidine; Cyclic AMP; Histamine; Histamine H2 Antagonists; Humans

1991
[Evidence for the presence of histamine H2 receptor on poorly differentiated human gastric cancer cell line, MKN45].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1991, Volume: 88, Issue:1

    Topics: Adenocarcinoma; Cell Line; Cimetidine; Cyclic AMP; Humans; Pyrilamine; Receptors, Histamine H2; Stom

1991
[Prevention of scald injury due to intraperitoneal hyperthermic perfusion for far-advanced gastric cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1991, Volume: 18, Issue:11

    Topics: Body Temperature; Burns; Cimetidine; Female; Histamine; Humans; Hyperthermia, Induced; Infusions, Pa

1991
Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Cimetidine; Cold Temperature; Cysteamine; Dose-Response Relationship, Drug; Duodenal Neopla

1990
Cimetidine use and gastric cancer.
    Epidemiology (Cambridge, Mass.), 1990, Volume: 1, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antacids; Case-Control Studies; Cimetidine; Esophagitis, Pe

1990
[Use of cimetidine with histamine in 4 patients with inoperable neoplasms of the upper part of the digestive tract].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1985, Oct-15, Volume: 38, Issue:20

    Topics: Adenocarcinoma; Aged; Carcinoma; Cimetidine; Drug Therapy, Combination; Esophageal Neoplasms; Histam

1985
Development of gastric argyrophil carcinoid tumors in a case of Zollinger-Ellison syndrome with primary hyperparathyroidism during long-term antisecretory treatment.
    Cancer, 1987, Jun-01, Volume: 59, Issue:11

    Topics: Carcinoid Tumor; Cell Division; Cimetidine; Female; Gastrectomy; Humans; Hyperparathyroidism; Middle

1987
Cancer occurrence in a cohort of patients treated with cimetidine.
    Gut, 1989, Volume: 30, Issue:11

    Topics: Cimetidine; Cohort Studies; Denmark; Female; Humans; Male; Neoplasms; Peptic Ulcer; Risk Factors; St

1989
Antisecretory drugs and gastric cancer.
    British medical journal (Clinical research ed.), 1985, Jun-22, Volume: 290, Issue:6485

    Topics: Aged; Cimetidine; Gastric Acid; Histamine H2 Antagonists; Humans; Middle Aged; Nitroso Compounds; Py

1985
Selective disappearance of histamine H2-receptor activity in the human gastric cancer cell line HGT-1 after short-term or chronic treatment by histamine or its H2-antagonists.
    Agents and actions, 1985, Volume: 16, Issue:3-4

    Topics: Cell Line; Cimetidine; Histamine; Histamine H2 Antagonists; Humans; Pyrimidinones; Receptors, Histam

1985
Pharmacology of histamine H2 receptor antagonists in the human gastric cancer cell line HGT-1. Structure-activity relationship of isocytosine-furan and imidazole derivatives related to cimetidine.
    Biochemical pharmacology, 1986, Jun-01, Volume: 35, Issue:11

    Topics: Cell Line; Cimetidine; Cyclic AMP; Histamine; Histamine H2 Antagonists; Humans; Kinetics; Pyrimidino

1986
Bile acids and gastric acid.
    Lancet (London, England), 1986, Aug-09, Volume: 2, Issue:8502

    Topics: Animals; Bile Acids and Salts; Cimetidine; Gastrectomy; Gastric Acid; Postoperative Complications; R

1986
Phase I clinical and pharmacokinetic study of taxol.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkaloids; Alopecia; Cimetidine; Dexamethasone; Diph

1987
[H2 receptor antagonist treatment and stomach cancer].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1987, Apr-30, Volume: 107, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Cimetidine; Female; Histamine H2 Antagonists; Humans; Male; Stomach Neo

1987
Morphologic stomach findings in rats and mice treated with the H2 receptor antagonists, ICI 125,211 and ICI 162,846.
    Toxicologic pathology, 1988, Volume: 16, Issue:2

    Topics: Animals; Carcinogens; Cimetidine; Female; Histamine H2 Antagonists; Male; Mice; Mice, Inbred Strains

1988
Cimetidine-mediated augmentation of lymphocyte responses to phytohemagglutinin in gastric cancer patients.
    Japanese journal of clinical oncology, 1989, Volume: 19, Issue:1

    Topics: Adult; Aged; Cimetidine; Dose-Response Relationship, Immunologic; Female; Humans; Lymphocyte Activat

1989
Effects of propranolol and cimetidine on cysteamine inhibition of gastric carcinogenesis induced in Wistar rats by N-methyl-N'-nitro-N-nitrosoguanidine.
    International journal of cancer, 1989, Mar-15, Volume: 43, Issue:3

    Topics: Adenocarcinoma; Animals; Cimetidine; Cysteamine; Gastric Acid; Gastric Mucosa; Gastrins; Male; Methy

1989
Healing of a malignant gastric ulcer with cimetidine.
    Journal of the Royal College of Surgeons of Edinburgh, 1988, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Aged; Cimetidine; Humans; Male; Stomach Neoplasms; Stomach Ulcer; Wound Healing

1988
Effect of cimetidine on inhibition by tetragastrin of carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
    Cancer research, 1988, Mar-15, Volume: 48, Issue:6

    Topics: Adenocarcinoma; Animals; Cimetidine; DNA; Gastric Acid; Gastric Mucosa; Gastrins; Hyperplasia; Male;

1988
Fungal colonization of gastric ulcers.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Female; Gastric Mucosa; Humans; Male; Middle

1988
The effect of cimetidine on chronic gastric ulcers in rats.
    The Australian and New Zealand journal of surgery, 1988, Volume: 58, Issue:2

    Topics: Adenocarcinoma; Animals; Cimetidine; Female; Male; Rats; Rats, Inbred Strains; Stomach Neoplasms; St

1988
Gastric cancer--delay in diagnosis and its causes.
    European journal of cancer & clinical oncology, 1987, Volume: 23, Issue:11

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antacids; Cimetidine; Family Practice; Female; Hospital

1987
[Gastric cancer and cimetidine].
    Revista espanola de las enfermedades del aparato digestivo, 1987, Volume: 72, Issue:4 Pt 2

    Topics: Aged; Cimetidine; Humans; Male; Middle Aged; Stomach Neoplasms; Stomach Ulcer

1987
Spontaneous regression of gastric lymphoma.
    Cancer, 1987, Oct-15, Volume: 60, Issue:8

    Topics: Aged; Aged, 80 and over; Cimetidine; Diagnosis, Differential; Humans; Lymphoma; Male; Metoclopramide

1987
Gastric carcinoma arising during five years treatment with cimetidine for duodenal ulceration.
    The British journal of clinical practice, 1987, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Cimetidine; Duodenal Ulcer; Humans; Male; Middle Aged; Stomach Neoplasms

1987
Gastric cancer following highly selective vagotomy.
    Postgraduate medical journal, 1987, Volume: 63, Issue:735

    Topics: Adenocarcinoma; Cimetidine; Humans; Male; Middle Aged; Stomach Neoplasms; Stomach Ulcer; Vagotomy, P

1987
Highly histamine-responsive clones from the human gastric adenocarcinoma cell line HGT-1.
    Agents and actions, 1986, Volume: 17, Issue:5-6

    Topics: Adenocarcinoma; Adenylyl Cyclases; Cell Line; Cimetidine; Clone Cells; Diphenhydramine; Guanylyl Imi

1986
The risk of gastric dysplasia in medical long-term treatment of peptic ulcer disease.
    Scandinavian journal of gastroenterology. Supplement, 1985, Volume: 111

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Female; Humans; Male; Middle Aged; Pe

1985