cimetidine has been researched along with Sore Throat in 14 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study showed that both drug regimens are significantly effective in preventing febrile attacks in PFAPA syndrome, and the presence of a MEFV gene mutation might not be the only significant risk factor for a response to colchicine." | 9.51 | Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations. ( Asna Ashari, K; Mousavi T, M; Raeeskarami, SR; Sadeghi, P; Vahedi, M; Ziaee, V, 2022) |
| "Cimetidine, as an immunomodulating agent, appears to be beneficial in the in-depth treatment of (P)FAPA syndrome." | 7.70 | [(P)FAPA syndrome: value of cimetidine]. ( Ansoborlo, S; Carrère, A; Guillard, JM; Perel, Y; Pillet, P, 2000) |
| "This study showed that both drug regimens are significantly effective in preventing febrile attacks in PFAPA syndrome, and the presence of a MEFV gene mutation might not be the only significant risk factor for a response to colchicine." | 5.51 | Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations. ( Asna Ashari, K; Mousavi T, M; Raeeskarami, SR; Sadeghi, P; Vahedi, M; Ziaee, V, 2022) |
| "The use of antibiotics and cimetidine in PFAPA syndrome are ineffective." | 4.86 | PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment. ( Athanasopoulos, I; Houlakis, M; Koudoumnakis, E; Parpounas, K; Peridis, S; Pilgrim, G, 2010) |
| "Cimetidine, as an immunomodulating agent, appears to be beneficial in the in-depth treatment of (P)FAPA syndrome." | 3.70 | [(P)FAPA syndrome: value of cimetidine]. ( Ansoborlo, S; Carrère, A; Guillard, JM; Perel, Y; Pillet, P, 2000) |
| "Cimetidine therapy was associated with the resolution of the fevers in 7/26 (27%) patients; tonsillectomy was associated with the resolution of the fevers in 11/11 (100%) patients." | 2.46 | A clinical review of 105 patients with PFAPA (a periodic fever syndrome). ( Feder, HM; Salazar, JC, 2010) |
| "PFAPA or Marshall's syndrome is characterized by abrupt onset of periodic episodes of high fever accompanied by aphthous stomatitis, pharyngitis and cervical adenitis, often associated with headache and / or abdominal or joint pain." | 2.44 | Oral aphthous-like lesions, PFAPA syndrome: a review. ( Buonaiuto, C; Cirillo, N; Femiano, F; Gombos, F; Lanza, A, 2008) |
| "Pharyngitis is the most frequent symptom associated with fever." | 1.72 | Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome: Clinical characteristics and treatment outcomes - a single center study in Japan. ( Kawano, Y; Ohnishi, T; Sato, S; Suganuma, E; Uejima, Y, 2022) |
| " If an underlying problem requires long-term immunosuppressive medication, it is wiser to choose cimetidine rather than increasing the steroid dosage to resolve atypical PFAPA." | 1.30 | PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis). ( Chen, LC; Huang, JL; Lee, KF; Lee, WI; Lin, SJ; Yang, MH; Yeh, KW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Raeeskarami, SR | 1 |
| Sadeghi, P | 1 |
| Vahedi, M | 1 |
| Asna Ashari, K | 1 |
| Mousavi T, M | 1 |
| Ziaee, V | 1 |
| Ohnishi, T | 1 |
| Sato, S | 1 |
| Uejima, Y | 1 |
| Kawano, Y | 1 |
| Suganuma, E | 1 |
| Amarilyo, G | 1 |
| Rothman, D | 1 |
| Manthiram, K | 1 |
| Edwards, KM | 1 |
| Li, SC | 1 |
| Marshall, GS | 1 |
| Yildirim-Toruner, C | 1 |
| Haines, K | 1 |
| Ferguson, PJ | 1 |
| Lionetti, G | 1 |
| Cherian, J | 1 |
| Zhao, Y | 1 |
| DeLaMora, P | 1 |
| Syverson, G | 1 |
| Nativ, S | 1 |
| Twilt, M | 1 |
| Michelow, IC | 1 |
| Stepanovskiy, Y | 1 |
| Thatayatikom, A | 1 |
| Harel, L | 1 |
| Akoghlanian, S | 1 |
| Tucker, L | 1 |
| Marques, MC | 1 |
| Srinivasalu, H | 1 |
| Propst, EJ | 1 |
| Licameli, GR | 1 |
| Dedeoglu, F | 1 |
| Lapidus, S | 1 |
| Kutsuna, S | 1 |
| Ohmagari, N | 1 |
| Tanizaki, R | 1 |
| Hagino, N | 1 |
| Nishikomori, R | 1 |
| Ujiie, M | 1 |
| Takeshita, N | 1 |
| Hayakawa, K | 1 |
| Kato, Y | 1 |
| Kanagawa, S | 1 |
| Feder, HM | 2 |
| Salazar, JC | 1 |
| Bharti, B | 1 |
| Bharti, S | 1 |
| Peridis, S | 1 |
| Pilgrim, G | 1 |
| Koudoumnakis, E | 1 |
| Athanasopoulos, I | 1 |
| Houlakis, M | 1 |
| Parpounas, K | 1 |
| Pinto, A | 1 |
| Lindemeyer, RG | 1 |
| Sollecito, TP | 1 |
| Kolokotronis, A | 1 |
| Markopoulos, A | 1 |
| Voutas, S | 1 |
| Mataftsi, A | 1 |
| Ikonomidis, P | 1 |
| Antoniades, D | 1 |
| Schorderet, DF | 1 |
| Femiano, F | 1 |
| Lanza, A | 1 |
| Buonaiuto, C | 1 |
| Gombos, F | 1 |
| Cirillo, N | 1 |
| Pillet, P | 1 |
| Ansoborlo, S | 1 |
| Carrère, A | 1 |
| Perel, Y | 1 |
| Guillard, JM | 1 |
| Lee, WI | 1 |
| Yang, MH | 1 |
| Lee, KF | 1 |
| Chen, LC | 1 |
| Lin, SJ | 1 |
| Yeh, KW | 1 |
| Huang, JL | 1 |
| Kibblewhite, DJ | 1 |
| Morrison, MD | 1 |
4 reviews available for cimetidine and Sore Throat
| Article | Year |
|---|---|
A clinical review of 105 patients with PFAPA (a periodic fever syndrome).
Topics: Child, Preschool; Cimetidine; Female; Fever; Histamine H2 Antagonists; Humans; Lymphadenitis; Male; | 2010 |
PFAPA syndrome in children: A meta-analysis on surgical versus medical treatment.
Topics: Adenoidectomy; Anti-Bacterial Agents; Child; Cimetidine; Fever; Glucocorticoids; Histamine H2 Antago | 2010 |
The PFAPA syndrome in oral medicine: differential diagnosis and treatment.
Topics: Analgesics; Anti-Inflammatory Agents; Child; Child, Preschool; Cimetidine; Diagnosis, Differential; | 2006 |
Oral aphthous-like lesions, PFAPA syndrome: a review.
Topics: Child; Cimetidine; Cytokines; Diagnosis, Differential; Fever; Histamine H2 Antagonists; Humans; Lymp | 2008 |
2 trials available for cimetidine and Sore Throat
| Article | Year |
|---|---|
Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations.
Topics: Child; Cimetidine; Colchicine; Fever; Humans; Lymphadenitis; Lymphadenopathy; Mutation; Pharyngitis; | 2022 |
A double-blind controlled study of the efficacy of cimetidine in the treatment of the cervical symptoms of gastroesophageal reflux.
Topics: Cimetidine; Double-Blind Method; Gastroesophageal Reflux; Humans; Incidence; Pharyngitis; Randomized | 1990 |
8 other studies available for cimetidine and Sore Throat
| Article | Year |
|---|---|
Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome: Clinical characteristics and treatment outcomes - a single center study in Japan.
Topics: Child; Cimetidine; Colchicine; Female; Fever; Humans; Infant, Newborn; Japan; Lymphadenitis; Lymphad | 2022 |
Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group.
Topics: Adrenal Cortex Hormones; Advisory Committees; Antipyretics; Child; Child, Preschool; Cimetidine; Col | 2020 |
The first case of adult-onset PFAPA syndrome in Japan.
Topics: Adult; Cimetidine; Cytoskeletal Proteins; Female; Fever; Glucocorticoids; Heterozygote; Humans; Japa | 2016 |
Randomized trial of adenotonsillectomy versus expectant treatment in PFAPA (periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis) syndrome: is the impasse over?
Topics: Administration, Oral; Child; Cimetidine; Fever of Unknown Origin; Follow-Up Studies; Glucocorticoids | 2010 |
Conjunctivitis as a sign of PFAPA syndrome.
Topics: Abdominal Pain; Child; Cimetidine; Conjunctivitis; Fever; Histamine H2 Antagonists; Humans; Lymphade | 2007 |
[(P)FAPA syndrome: value of cimetidine].
Topics: Child; Child, Preschool; Cimetidine; Enzyme Inhibitors; Female; Fever; Humans; Infant; Lymphadenitis | 2000 |
PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis).
Topics: Azathioprine; Child; Cimetidine; Fever; Humans; Immunosuppressive Agents; Infant; Lymphadenitis; Mal | 1999 |
Cimetidine treatment for periodic fever associated with aphthous stomatitis, pharyngitis and cervical adenitis.
Topics: Adolescent; Child; Child, Preschool; Cimetidine; Fever; Humans; Lymphadenitis; Male; Periodicity; Ph | 1992 |